Basic Information

Insect: Megachile lagopoda
Gene Symbol: -
Assembly: GCA_036983795.1
Location: CM072786.1:9489863-9493249[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 2.8e-05 0.0033 18.4 0.8 1 23 100 123 100 123 0.94

2 12 0.01 1.2 10.3 4.6 2 23 251 273 251 273 0.91

3 12 0.0003 0.034 15.2 1.5 2 23 317 339 316 339 0.95

4 12 5.6 6.5e+02 1.7 7.6 3 23 424 445 423 445 0.95

5 12 1 1.2e+02 4.1 2.2 1 23 494 517 494 517 0.93

6 12 0.0012 0.13 13.3 0.4 2 23 567 589 566 589 0.94

7 12 0.00011 0.013 16.5 0.1 3 23 612 633 610 633 0.93

8 12 0.0073 0.85 10.8 3.6 2 23 675 697 674 697 0.96

9 12 0.099 11 7.2 4.2 3 23 712 733 710 733 0.92

10 12 0.00025 0.029 15.4 0.1 2 23 777 799 777 799 0.94

11 12 0.12 14 6.9 1.7 1 23 878 900 878 900 0.98

12 12 0.00046 0.053 14.6 0.6 2 23 914 936 913 936 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	2.8e-05	0.0033	18.4	0.8	1	23	100	123	100	123	0.94
2	12	0.01	1.2	10.3	4.6	2	23	251	273	251	273	0.91
3	12	0.0003	0.034	15.2	1.5	2	23	317	339	316	339	0.95
4	12	5.6	6.5e+02	1.7	7.6	3	23	424	445	423	445	0.95
5	12	1	1.2e+02	4.1	2.2	1	23	494	517	494	517	0.93
6	12	0.0012	0.13	13.3	0.4	2	23	567	589	566	589	0.94
7	12	0.00011	0.013	16.5	0.1	3	23	612	633	610	633	0.93
8	12	0.0073	0.85	10.8	3.6	2	23	675	697	674	697	0.96
9	12	0.099	11	7.2	4.2	3	23	712	733	710	733	0.92
10	12	0.00025	0.029	15.4	0.1	2	23	777	799	777	799	0.94
11	12	0.12	14	6.9	1.7	1	23	878	900	878	900	0.98
12	12	0.00046	0.053	14.6	0.6	2	23	914	936	913	936	0.93

Sequence Information

Coding Sequence: ATGGCGAACgagacgacgacgacgatatCGGAATTGACGGAATTGGACAGCGATGGATCGAGTTGCGGGGAACGGGACGTCAGGAAACGTCTCCGCGTTGACGCAGATTCGACCGGGCCGAAGAAGAGACGAAAACAGACGACCCCCGTAAGATTCTCGTCCGCGCTGATGATGAGCGGCGTGCACGAGGAGTCGAACGAGgacgaggacgaggacgaGGACAGCGAAGGTAAGCTGTCGTCGCAGTCACCAATACCGAGTCAATCGTCGATCAGGGACGAGAACCTCAATAACGAATTCCGTTGCCAGTACTGCGGTCAGTTTTTCGATAGCAAGGATACGTTGAACGTTCATCTCGATAACGAGCACGGTTCCGCGAATCAGTCGTCTCAGCAGGGTCAAAGCGGATACTCGAGTAGCGCGATTAAACAGGAACCGTCTCAACAACTGGACCAAACCGAGATTCCCGTTAATCTGCTTAGCGTGAAGAATTTCGCGATAAATTGGCTGGCTACCGGACAACACGTGCAATCGCACGTGCAAATGCAGCCGCAGAACGAGGACTCGTGGCCAACCGGTACAGCCAGTCAAATCACCTCGTTGCCCAATCACCTGCAGGTACTCTCTTCCGGTTTCCCTGGTTCCTTGACGCAGTATCTATCTCTGCCCACGTTCCCGTTAACGGACTCTGGTCCGATCGCGAGATCCTCGATAGGACCGACGCCGGTGAGAATCTTTAATCCGGACGCGTACTGCGATCTGTGCAATAAAGAGTTCTGCAACAAGTATTTCTTGAAGACGCACAAGGCGAACAAGCACGGGATCTACGCGGATTCGCCGGGACCCAGCTCGGTAGACAATAACGTCGTAACTCCCATGTATCCCGCTAACTTTTCTAACAACTTAGTCAAACTGGAACCACCCGCGACGCCACCCACACCCAGCGTACCCTGTGACCTCTGCCAGAAACGCTTCAAGAACGAGGATTCGATGCGCAAGCACAAACAGAAAATGCACACCGATCTGCCGGATCAGTCGCAGGAACCGCAGATCAATCTATCGCAAAGCGAGGAGGACACGGAAACACCGAGAAACAATTTCGCGAGCATCGAATCGTTTTTCAAACAGGAATACGGCGTGGAACAGGAGGACACGTCGTTCATGCCTGCGCCTAGACACCTATCTCCCCAGTCGATTCAACAGGCACGGGACTCCGGTTTTAACGCTGATCGGCTTCGACGTTTAGGAGTGATAAATCCGGAGGCGTTCTGCGAGATCTGCTGTAAAGAGTACTGTAACAAGTACTTCCTGCGAACGCATAAAATGAAGAGGCACGGCATCGTCGTTCAAGATAGCGAGAGGTCGCCGGGTAATCCAGGATCAGCGCCCACTTGGCATCAAGTGCAAACCAGCCCGTTAAATTTGATCGTGGCGGAGAGCGCGAGCAGCACCGAGTCGAACGAACGGCCAGGGGACGACTACGAGTGCAAACCCTGCGGAATACGATTCCAGACGATCGATCTTTATCAGACGCATTGCCGGAAGATGCACGAGAGCGAGGAGCAACGGTCGCCCAAGCAGGAGTGCGAACTCGAGACACCGACCGACCAGCCGAACGATTCCATCTCGGAGGATCTTCAAAAGTTGCAGACGATGCTGTTACAGCTGAACGGACTGAAGTCCAGCAAGCAGGGATTGTCGTGCAACGTGTGCGGAAAGGAATACGACACCAGAACCGCGTTGCACATTCACGCGACGACCGAACACGCGTCCATCCCTGAAGATCCGACCTCGCCGCAAGAGAAGTCACCGTTGACCGCGACGTCCATGTTCTGCACCCTGTGCGGGAAGGACTACGCGAGTCAGGACGCCCTCAGAAGACACATAGCGGAGGAACATCAGCCACCGATAATGAACACCCTTCCTCAACCACCCCCGACTACCTCCACCACAACCAACTCGAACGCGACGAGTCAAAGCACCTCCGAGAGGAAGGTGACGTCGATGACGCCCACGTCGAGCTACTGCGAGATATGCAACAAGGAGCTGTGCAATAAGTACTTCATGAAGACGCACATGCAGAGGATGCACGGTATCGAGATCGAGAACGGTGCTCAGATCGGTGGCGTGATATGCAACATCTGTAACAAAGAACTGTGCAGCAAGTACTTCCTGCGAGTGCACAAGCACAATACTCACGGAATAGTGGACGAGAATGCGCCCAGCTCGGTGAAACAAGAATCGCTCGAGGCCACGAACACCGACGATGCCCTGAAGCCGGAGCAACTCGGGGATTTGAGTCACAGGTACTTCACCCACTTTACGGAGGTTTGTCCGATCTGCAGCAGAAGGTTCCGCAGCATAAAGTGGCTGAAGGCACACTTGATGGGCGAGCACGGGAAAGTGGGCATCGACAAATGGCGCGAGATGGAGCAACATTATCAGACAGCGTCCAGAACAACGAACAGGACCACCAGCACGCCGAAAAATACTCAGCAGGGCTCGAACTTGAAGATACCGAACGGATTCGAGATTACGCAGCAGCTCAAGCCGGCGGACTACACCGGTTTGGGGAACCAAGTGCTGTCTAATTTGCTGGGATCATCTTCCGAGGATCAACAGCTGAAGAGCTATCGTTGTTCCTATTGTACGTTCACGACCACCGTGCTGCCGTTCCTTTTTCTTCACGAGAGATCTCACGTGCACTCCCGGGAAAATGCGGAGGGGGAGAAATCACTTCAGTGCCCGATTTGCTCGCAGAGCTTTCATCAGCCCGAGCTGTTGCACCAACATCTACTCGCGGCGCACCAGTTTCCCACGTTGTTGTCCCATTTTCCACCGCCGATGCTGAACAATTTAACACCCGACGCGGAGAAACTGAACGAGGTCAAGGAGAGGCTGGAGCTGGAATCAAAAGAGGATCGTATCGGGAACAGTCCGCAAGTCACTGCCAACAAAAGCGTCCCGGAGCCGATCAGAAATCAACGACAAGACGACACGTCGGTTCAAGTCACTCCTCAGGGTGTGTACAAGTGCGCGCAGTGTTGTTACGCCACGACCAATCTGAACAGGATCAAGAAGCACGTCAGAAAGGATCACAGGACCATCGGTGACCCCACCGACAGCGTGATAGCGGAGCTAGGTAGAACCCTGAAGGACGTTGCCAACAGACACAAGATGCCGGCTTGCTACGCGATGCCGCAGGACACGAACTCGAATCCTGACAAAACTATCATGCAACCGTTCCTGATCGAGGAACAGGACGCGATGCAAGCCGGCGAGGAGTCCGGCTCGGATAAACGATTCGCGCCGGCTTTGGTTTATTTACCGGTTAAATCGAGAATTAACAATCCCCTCACCGCATCCTTCACACTCAGCCCCGCTTGA
Protein Sequence: MANETTTTISELTELDSDGSSCGERDVRKRLRVDADSTGPKKRRKQTTPVRFSSALMMSGVHEESNEDEDEDEDSEGKLSSQSPIPSQSSIRDENLNNEFRCQYCGQFFDSKDTLNVHLDNEHGSANQSSQQGQSGYSSSAIKQEPSQQLDQTEIPVNLLSVKNFAINWLATGQHVQSHVQMQPQNEDSWPTGTASQITSLPNHLQVLSSGFPGSLTQYLSLPTFPLTDSGPIARSSIGPTPVRIFNPDAYCDLCNKEFCNKYFLKTHKANKHGIYADSPGPSSVDNNVVTPMYPANFSNNLVKLEPPATPPTPSVPCDLCQKRFKNEDSMRKHKQKMHTDLPDQSQEPQINLSQSEEDTETPRNNFASIESFFKQEYGVEQEDTSFMPAPRHLSPQSIQQARDSGFNADRLRRLGVINPEAFCEICCKEYCNKYFLRTHKMKRHGIVVQDSERSPGNPGSAPTWHQVQTSPLNLIVAESASSTESNERPGDDYECKPCGIRFQTIDLYQTHCRKMHESEEQRSPKQECELETPTDQPNDSISEDLQKLQTMLLQLNGLKSSKQGLSCNVCGKEYDTRTALHIHATTEHASIPEDPTSPQEKSPLTATSMFCTLCGKDYASQDALRRHIAEEHQPPIMNTLPQPPPTTSTTTNSNATSQSTSERKVTSMTPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVICNICNKELCSKYFLRVHKHNTHGIVDENAPSSVKQESLEATNTDDALKPEQLGDLSHRYFTHFTEVCPICSRRFRSIKWLKAHLMGEHGKVGIDKWREMEQHYQTASRTTNRTTSTPKNTQQGSNLKIPNGFEITQQLKPADYTGLGNQVLSNLLGSSSEDQQLKSYRCSYCTFTTTVLPFLFLHERSHVHSRENAEGEKSLQCPICSQSFHQPELLHQHLLAAHQFPTLLSHFPPPMLNNLTPDAEKLNEVKERLELESKEDRIGNSPQVTANKSVPEPIRNQRQDDTSVQVTPQGVYKCAQCCYATTNLNRIKKHVRKDHRTIGDPTDSVIAELGRTLKDVANRHKMPACYAMPQDTNSNPDKTIMQPFLIEEQDAMQAGEESGSDKRFAPALVYLPVKSRINNPLTASFTLSPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00224784;
90% Identity: iTF_00963435;
80% Identity: -