Mrus005455.1
Basic Information
- Insect
- Machimus rusticus
- Gene Symbol
- -
- Assembly
- GCA_951509405.1
- Location
- OX608049.1:37742564-37746900[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 3.3 6.1e+02 2.4 1.9 2 20 191 209 190 213 0.91 2 19 0.00089 0.17 13.6 2.9 2 19 256 273 255 276 0.93 3 19 0.54 1e+02 4.9 4.5 3 23 288 308 286 308 0.85 4 19 0.00015 0.027 16.1 0.2 3 23 317 338 316 338 0.95 5 19 9.1e-05 0.017 16.8 0.3 1 23 344 366 344 366 0.96 6 19 0.018 3.4 9.5 0.8 1 23 372 395 372 395 0.95 7 19 0.00012 0.023 16.4 2.9 1 23 400 422 400 422 0.98 8 19 1.4 2.6e+02 3.6 0.8 2 23 432 453 431 453 0.93 9 19 0.0027 0.5 12.1 0.5 1 23 470 492 470 492 0.96 10 19 0.02 3.7 9.4 1.8 1 23 497 519 497 519 0.97 11 19 0.14 27 6.7 2.0 1 23 535 560 535 560 0.96 12 19 0.00012 0.022 16.4 0.3 2 23 567 589 566 589 0.95 13 19 0.0015 0.27 13.0 0.5 1 23 594 617 594 617 0.97 14 19 0.0053 0.98 11.2 0.6 1 23 622 645 622 645 0.93 15 19 2.4e-05 0.0044 18.6 0.4 1 23 648 671 648 671 0.97 16 19 0.73 1.4e+02 4.5 3.9 1 23 677 700 677 700 0.89 17 19 0.019 3.6 9.4 0.3 1 23 706 728 706 728 0.98 18 19 1.6e-07 3e-05 25.4 1.8 1 23 734 756 734 756 0.99 19 19 0.0024 0.45 12.3 0.1 1 23 762 787 762 787 0.98
Sequence Information
- Coding Sequence
- atgccacCGCCGAAAAAGCGTGGTCGTCCTCCAAAGGCAAAATCGACAAAGTGCGTTAGTTGCGCCGTCGATATGAAGCAGCCCTACCAACTCATATTCGATGAAAGTGGTGTTGAGCTAGAACTGCAGAAATTGCTTTCCACTTGCTTTGGGATGCGTGTTGTGAAGGATAAAAAGCAAATTCAGGCTCTCTGCGAGGATTGCCTTAATCGTCTAATTGATGTCTTCGATGTTATGCAAAAGAAAAACCAGGAAGAGCCTGGGCCGTCTACGAAGACCCCAGAACTTCCACAAATAAAagatgaatttgaaaattttgacctcgaaaatgaagaaatttatgaGGTCATTGAAGAGCCGGaaataattaatgttaaaGATTCAGATCTAACTGAGTTTGAAGAAGAAACACAAGCAGCCAACAATCCTATTGAGGGTAATGAAAATGATCCTGGAGGATTTGAAAGTATTGATTACTTAGAAGATTTCGACGACGAGATCGATATTAGGGAATATAAAATCGGAATCCTACAAAATACTCTTTCTTGCTTAATACTTCCTGAAAGTATTCAATGTCGGTTATGTTCTGAAAGTTTCGAAAAACACGCTGATGTACTAAGTCACACCGAATGCACACATTGTGTCGAGGATTTTGCCTATCCTTGTATAATTGACGAAAATTGTGAACCACAAAAATCAACGATGGACCTTTCGTTGCACTTAGTTTTCAAGCATTACGACTTGGAAAAaTTAACGATCTACACTCAATGCCCTGAATGTGATAAAAGATTCAACAACTTTTCGCTTTACAACAAACATTCATGCTATGTTGGTGGAAAAATTTCACGAAGTGCAACTGATTGCGTAAATTGTGGTAAATCGTTCAAGTCGAATAAGAGATATCGCTTCCACCACAATTTTCATCAAGAAAAAAGACGTCcaaaagcttgttttattTGCGATAAGTCGTTTAGAGATGAAGATGAATTTTACGAGCATATTATGTATCAGCATGAGAAAAACCTTGGGTTCGTTTGTTTAAgTTGTGACATGTCATTcactaatgaagaaaatttaaaaaaccatgAAAGTATACATAAAGTTGAACGGCAGTATAACTGTAAGCTGTGTAGCAAATCTTACCTCTATAATCAGCTTTTAAAGGATCATATGGTATCAGCTCATGGAACAAATCCTTTCAAATGCCACATTTgtgataaatatttgattaagaAAACACTTCTGAACAAACACATTTTATCGCATTCTGTACCACAAGCAACTGAAGTGTTGACTTGCAGTTGTTGCGggataatttttgaaaaatctgaGGAATCTGAGGATCACATGAATAAGCACAATGAAAGCGATGAAGCAACCGTTATAAccgaagaaattgaaattgcatATTGCTGTGAATATTGCGAGCTTGCTTTTAATTCTATCGACAATATGATCGCCCACCGAGAGCTTCACGACAAAAAGACATATTTCTGTGACTTATGTCCTCTAAACTACAGcgagtataaaaaattaaaaacgcatAAACTGACTCATTTTAATTATGTGGACAAAAGATACACTTTCCCGGTTATTAGACACTATGTTTGCGATTTTCCgGACTGCACGATGAGTTATTTGCAATGGACTAGTCTTCGATCACATAAAAGGCACAAACATTGTCATCAGAAGAGTGTTCAATGCCCCAAATGTTCTGAAGCATTCACGGATATgcaacaatataaaaaacacaTGGAAAATGTCCACAAAAGCACTGCTTTTAAATgccaattttgcaataaagaCTATGGCAACAACATGGCTTTAGCGGTTCACATTTCGAGGCGGCATAACGcaaGTCGTTTTCAGTGCGATTTATGTGAGCAAAGCTATTCGACGAAGGCTGTTTTGGACAAgcataaaacaaatattcacAGCAGCTTCCCATGCACGATTTGCggaaaagtattaaaaaacttaaagaatttCCAGGTCCATAATCGAATGGTTCACGAAAAGGAGAAAAGGTATTTTTGCAAGTATTGCAACAAAGGCTACTTCAATAACTGCGATAAAATGGAACACGAATCATCGgtgcatgaaaaagttaaaaaatatgtttgcgACTTGTGTCCGTATTCAGCAGTGTATAAAGAATGTTTAGTGGTTCACAAAAGAGCGCACCGAAATGAAACGCCTTATAAATGCGAGCTCTGCAACAAAGGCTTTCGGCGAAATTATGCTCTACGCGTTCATATGAAGCGGCATTACAACACCAAGGAttttacttGCCCCTACGAGGACTGTGGGGCTTCCTATGCAAATCagggaattttaaattaccacATAAAAACGAAGCATGGCGAAGATGCTAATAAAGAACCAAAAGCGAAGCGGAAGCGATTGGCTGGGGATGGTTTTCATCGTCCGCGGTATGAAGAATCTGCGGAATTTTTTGttgacgacgacgacggttTGGACGATGGTGTTATTGGGGAACCGAGCACTCAAGCGTTCGaagaagatgatgaaataATCCCCAATGATAATATTGACTATATTGAAAAGGATGTCGAGTCTGGTACAGGCGTTCCTGTACAGAAAATTGAATCAGATCACAATTATATTGTGGAAGAAGTATTCGAAGTTGTTATGCaagatatataa
- Protein Sequence
- MPPPKKRGRPPKAKSTKCVSCAVDMKQPYQLIFDESGVELELQKLLSTCFGMRVVKDKKQIQALCEDCLNRLIDVFDVMQKKNQEEPGPSTKTPELPQIKDEFENFDLENEEIYEVIEEPEIINVKDSDLTEFEEETQAANNPIEGNENDPGGFESIDYLEDFDDEIDIREYKIGILQNTLSCLILPESIQCRLCSESFEKHADVLSHTECTHCVEDFAYPCIIDENCEPQKSTMDLSLHLVFKHYDLEKLTIYTQCPECDKRFNNFSLYNKHSCYVGGKISRSATDCVNCGKSFKSNKRYRFHHNFHQEKRRPKACFICDKSFRDEDEFYEHIMYQHEKNLGFVCLSCDMSFTNEENLKNHESIHKVERQYNCKLCSKSYLYNQLLKDHMVSAHGTNPFKCHICDKYLIKKTLLNKHILSHSVPQATEVLTCSCCGIIFEKSEESEDHMNKHNESDEATVITEEIEIAYCCEYCELAFNSIDNMIAHRELHDKKTYFCDLCPLNYSEYKKLKTHKLTHFNYVDKRYTFPVIRHYVCDFPDCTMSYLQWTSLRSHKRHKHCHQKSVQCPKCSEAFTDMQQYKKHMENVHKSTAFKCQFCNKDYGNNMALAVHISRRHNASRFQCDLCEQSYSTKAVLDKHKTNIHSSFPCTICGKVLKNLKNFQVHNRMVHEKEKRYFCKYCNKGYFNNCDKMEHESSVHEKVKKYVCDLCPYSAVYKECLVVHKRAHRNETPYKCELCNKGFRRNYALRVHMKRHYNTKDFTCPYEDCGASYANQGILNYHIKTKHGEDANKEPKAKRKRLAGDGFHRPRYEESAEFFVDDDDGLDDGVIGEPSTQAFEEDDEIIPNDNIDYIEKDVESGTGVPVQKIESDHNYIVEEVFEVVMQDI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00717985; iTF_00628589; iTF_01461371; iTF_00936755;
- 90% Identity
- iTF_00717985;
- 80% Identity
- -