Lhir010486.1
Basic Information
- Insect
- Lycia hirtaria
- Gene Symbol
- iec1
- Assembly
- GCA_947563715.1
- Location
- OX387376.1:4022987-4031430[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 9.5 7.6e+02 1.6 1.2 3 22 454 473 453 476 0.90 2 12 0.087 7 8.0 0.7 2 22 498 518 497 521 0.89 3 12 0.024 1.9 9.7 6.1 1 23 535 558 535 558 0.97 4 12 0.022 1.8 9.8 1.4 3 22 565 584 563 587 0.88 5 12 0.024 1.9 9.7 0.0 2 21 638 657 637 658 0.95 6 12 5e-06 0.0004 21.3 1.0 1 23 716 737 716 737 0.98 7 12 2.4e-05 0.002 19.1 1.1 1 23 743 766 743 766 0.97 8 12 0.047 3.8 8.8 2.0 2 21 787 806 787 807 0.94 9 12 0.086 6.9 8.0 0.3 1 23 819 843 819 843 0.95 10 12 0.012 0.97 10.7 6.4 1 21 851 871 851 873 0.95 11 12 0.0033 0.26 12.4 3.0 1 21 879 899 879 904 0.93 12 12 0.0012 0.097 13.8 2.0 1 23 910 933 910 933 0.95
Sequence Information
- Coding Sequence
- ATGCTGTCCCCTCGTGAAGATGATGATGATGATACCCATCTATGCATCAAATGTAACACTACCATTGTCGGCTTGGACAACTACGTCAAGCATAGGAAGGAGCGATGTGGAAAAACCAAGGCCAATGAAAACAAATCTGATCTTCCGCCCATAGACTCACTAGACCCTGCATACAGCTTAGGAGCCGATGTTTTCTTTCAATCTTTGGAGCTGCAGAGCAGCGTCAAGAAAACATCACTATCTAGACTAACTCCTCCTATACCCATCTCAAAACCCAACATAGACAGAAAGAGCTCTTTAGCCATTGCATCGACATCACGAGATATCCCTCGGATGAGTCCTCTTGAAAGCAATCTAAGAGGAGAAGACTGGATAGGGGGTCATTCACTCAGGATAAGTGGAAATGTAGACAATCAAACGAAACTTATAAACGCTGTAGCCAGCATCAGTGGTGCAGCTAAAAAGGAAACGAGCTCATCTTATACAATAAATTATAATGATTTCAAAGCTGCTGAAGATGAAAGCGATGAATCTGAAGTTTCAGACGATGACGATGATGAAGAACACGCCACAGGCGGAAAATGGAAGCCACCATCAAGTTATACAGGAGGGAAATGGCGGCCTGATTATCCAGAACATGAATGGGATGATCAGGAACATACACCGACGTGGAGAACTCTCTTGCCTGAAGTAGAACGTGAAGAAGACTATGACGCTCCACCACCAGGTCACACAAAAGGTAAATGGGTTCCAGGAGCGAATGAAAAAACTCAAATAATGCAAACAACTATACAGACAAAAGGGTCAGTCCAATATTGGTGTGGTCCTTGCAACAGAAGATTGGGCTCTCGAGCTATTTACGATAAACATTTAAGATCAAGTTTGCATTTGAAGAAAGTGCTGCCAGAGCATGAATTGGAATTTTCTGGACACCTAGAGCCGATGAAAATGAGTGAAAAGCGCACTACGAGACCTTCAAAATTTGTAAATGACGGCGTCTATTCTCAAATTGAAAGAAAGAAACGGCAGAAGAAAGATGTTACACTCAATACCAAAACGGAAACTAAGAAGAGAAAACGGAGGGCTACTTTCGTTCACTGCGCTGGCTGTAATTCTCGAGTCCGAGAGTATTTAATGGGAAAGCATCTTATATCTCATTACCACTTCCGAAAAGCAGCAGGAGTTACAAGTTCTATATATCAACAACTTATTCTAGACAATATTGAGGCTATCGTTCACCAGTCTCCATTTCAATGCAGTCCTTGCAAATTTTACACCAACTTGCTTCCAAATTTCATGCACCACTGGTACTCAGATGAGCATGAATGGAAGGTAGCATTTATTGAAGGAAATTTCTGGTGTTCCTTTTGTAAATTTGAATGTGGATCTTCTCAAGAAATGCTACAACACATGTCAAGTCCAGACCACGGAGAAGTTGTAGCTGTCATAAACAGATCGATGCCTATTATCATTCGAAAGAAAACTGTTTTAAAATGTGAGACGTGCTCTGGAATTTTTCGATATAATATAGAATTAAAAAAGCACAGTCAGAAAACTGGACATCCATTGGCATACACGGCAACAGACACTTATCAGGAGCTACACAAGTGTCAGCACTGTAAATCCAAGTTCAAGACGTCGCTGACCCTTGCAGCGCATTTAAAGTCAAGGCACAAACACAAAACTCATCTATGCCTGGTTTGTTCCAAGACCTTCGACTCTTCAGAAGAAGCCAAGCGCCATCGTCAGTCATCTGAGCATAGAATCAATCGGAAGGAAATGCTGATGAAACAGGGTGTAATAACAAAGGATCTAAGGAAAAAATGTCCTTATTGCCCTGGCGATGTAATGTTAAAAAATGTTTTGGTTCTCAAGGATCACATTAAGACAATTCATCCAGATGTTAAGAAAACGTGCCCAAAATGTGGTATGGAGTTTATACTCTCGCAAGAAGTAACCAGCCATATCAGAGCCAAAGCGTGCAAATTTAAACAGACCCTACGCTCTTTAGAATCCTACTGGAACTGCAGTCAATGTCTCTTCACAACTGACTCTCAAGCCGAGTGTTTCTTCCATGAAGTATTGCATGATCCTCCACAAACGGAAATAAAAAAAATTGGAGACAATGAAAAAGTAATACAGAAGTATACGTGTCCATTATGCCCGAAGAGTTTCAGGAAGGCTTCGTTGAGGCAGCATTTGAGACAGCACACGTTTGAAAGGCCGTTTATTTGTTCCATCTGCAAAGCTAACTTCACTCGGCAGACCAGTCTGACAAATCACGTGAGGAAAGACCATGGAGATGGTTCGCAAAAGGTGCCCAATCCGACAAATGCTTTAGCAGAGATTGAACGACGGAGCTGTGAAAAATGTTTGCAAGGTTTTCCTAACAAGAGTATGCTGTCACACCACATCTGCAATGCTGATGCTAACAGCGACAGTGCTCCGTGTGTCCACAAGTGTCTTATTGAACAGTGTGGTTTTGTAGCAGCGAGCGCTGTCCAGCTTTTTAAACATGTAAAAAGTCACGGAACTATTGTTGGACAACGCCACAAATGTCCGCAGTGCCCCTTTCAAACCAACCAAGCCAGTCATTTAAAGAGGCACTTGCGATGCCATAAGGGAGACAAACCGTACTCGTGCCCATATTGTCATTTCACTTGTGGAAGTCTTGAAAATCTTCGGAAACATGTGCTTCGAAGCGGCCGCCACAAGGACTTGTTCCTGTACCAGTGCAAACATTGTGAATATAAAACTAACATGGCTTCAGAGTTGCGGAAGCATTTAGTCAGCGACCACAGCGACCTATACAACGTGAAAACTGCTTCTGAAGCCGCCAAAATACATTTGATGAAAATCTCAGATTAG
- Protein Sequence
- MLSPREDDDDDTHLCIKCNTTIVGLDNYVKHRKERCGKTKANENKSDLPPIDSLDPAYSLGADVFFQSLELQSSVKKTSLSRLTPPIPISKPNIDRKSSLAIASTSRDIPRMSPLESNLRGEDWIGGHSLRISGNVDNQTKLINAVASISGAAKKETSSSYTINYNDFKAAEDESDESEVSDDDDDEEHATGGKWKPPSSYTGGKWRPDYPEHEWDDQEHTPTWRTLLPEVEREEDYDAPPPGHTKGKWVPGANEKTQIMQTTIQTKGSVQYWCGPCNRRLGSRAIYDKHLRSSLHLKKVLPEHELEFSGHLEPMKMSEKRTTRPSKFVNDGVYSQIERKKRQKKDVTLNTKTETKKRKRRATFVHCAGCNSRVREYLMGKHLISHYHFRKAAGVTSSIYQQLILDNIEAIVHQSPFQCSPCKFYTNLLPNFMHHWYSDEHEWKVAFIEGNFWCSFCKFECGSSQEMLQHMSSPDHGEVVAVINRSMPIIIRKKTVLKCETCSGIFRYNIELKKHSQKTGHPLAYTATDTYQELHKCQHCKSKFKTSLTLAAHLKSRHKHKTHLCLVCSKTFDSSEEAKRHRQSSEHRINRKEMLMKQGVITKDLRKKCPYCPGDVMLKNVLVLKDHIKTIHPDVKKTCPKCGMEFILSQEVTSHIRAKACKFKQTLRSLESYWNCSQCLFTTDSQAECFFHEVLHDPPQTEIKKIGDNEKVIQKYTCPLCPKSFRKASLRQHLRQHTFERPFICSICKANFTRQTSLTNHVRKDHGDGSQKVPNPTNALAEIERRSCEKCLQGFPNKSMLSHHICNADANSDSAPCVHKCLIEQCGFVAASAVQLFKHVKSHGTIVGQRHKCPQCPFQTNQASHLKRHLRCHKGDKPYSCPYCHFTCGSLENLRKHVLRSGRHKDLFLYQCKHCEYKTNMASELRKHLVSDHSDLYNVKTASEAAKIHLMKISD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00143496; iTF_00207433; iTF_00045002; iTF_01172875; iTF_00206589; iTF_00667005; iTF_00818758; iTF_00390922; iTF_00056140; iTF_00827502; iTF_00033380; iTF_00826319; iTF_00635893; iTF_00936181; iTF_00634999;
- 90% Identity
- -
- 80% Identity
- -