Bbet004702.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Biston betularia
Gene Symbol
iec1
Assembly
GCA_905404145.1
Location
FR989866.1:16042470-16052367[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0067 0.54 11.4 0.6 2 22 497 517 496 520 0.89
2 10 0.0024 0.19 12.8 4.8 1 23 534 557 534 557 0.97
3 10 0.022 1.7 9.8 1.4 3 22 564 583 562 586 0.88
4 10 0.023 1.8 9.7 0.0 2 21 637 656 636 657 0.95
5 10 1.5e-06 0.00012 23.0 0.8 1 23 715 736 715 736 0.98
6 10 2.3e-05 0.0019 19.2 0.8 1 23 742 765 742 765 0.97
7 10 0.37 29 6.0 0.2 2 23 815 838 814 838 0.95
8 10 0.075 6 8.1 7.6 1 21 847 867 847 869 0.94
9 10 0.002 0.16 13.1 1.8 1 21 875 895 875 900 0.92
10 10 0.015 1.2 10.3 3.1 1 23 906 929 906 929 0.92

Sequence Information

Coding Sequence
ATGTTGTCACCTCGTGAAGATGATGATGATGACACACATCTATGCATCAAGTGCAATACTACCATCATTGGGTTAGATAACTACGTCAAGCACAGAAAAGAACGTTGTGCAAAACCCAAAACCAACGAAAACAAACCTGATCTTCCCCCTATCGAATCTCTAGACCCAGCCTACAGCTTGGGAGCTGATGTATTCTTCCAATCTTTAGAATTACAAAGTAGTGTTAAAAAGACCTCTTTGTCTAGACTAACACCTCCCATAGCTATTTCAAAACCAAGCATAGATAGAAAAAGCTCCTTAGCCATTGTTTCAACGTCACGGGATATCCCGCGGATGAGTCCTCTCGAAACTAATCTGAGAGGAGAAGACTGGATAGGAGGCCACACGCTCAGAATAAGTGGCAATGAAGATAATCAAACTAAGCTCATAAATGCCGTGGCTAGCATCAGTGGCGCAGCAAAAAAGGAAACTAGCTCTTCTTACACAATAAACTATAACGATTTCAAAGGCGATGAGGAAAGCGACGAATCTGACGTTTCTGATGAAGATGACGAAGAAGATCATCCTTCAGGGGGGAAATGGAAACCACCTTCAAACTACACCGGAGGTAAATGGCGGCCAGATTTTCCAGAACATGAGTGGGATGACCAGGAACACACAACAACGTGGAAATCTCTCCTACCTGAAGTCGACCGAGACGAAGATTATGATGCTCCACCACCAGGACATACTAAAGGTAAATGGGTCCCAGGGGCAAATGAAAAAACTCAAATAATGCAGACTACCATACAGACAAAGGGATCAGTTCAATACTGGTGCGGACCATGCAACAGACGACTTGGCTCTAGAGCTATTTACGACAAACATCTAAGATCAAGCTTACATTTGAAGAAAGTCTTACCAGAACATGAACTGGAGTTTTCTGGACATTTGGAGCCAATGAAAATAAGTGGAAAGCGTACGACGAGACCTTCCAAATTTGTAAACGACGGTTTATATTCTCAGTTTCATAGAAAAAAGAGACAAACAAGAGAAGTTAAGTTAAACATTAAAATTGAAACTAAGAAAAGAAAACGGAGAGCTACTTTCGTACATTGCGTGGGCTGTAATTCTCGTGTGCGCGAATATTTAATGGGAAAGCATCTGATATCTCATTACCACTTTAGAAAGGCAGCAGGAGTGACAAGTTCCGTGTATCAACAGCTTATTCTCGACAACATTGAGGCGATCGTCCATCAGTCTCCTTTCCAATGTAGTCCATGTAAGTTTTACACCAACTTGTTGCCAAACTTTATGCATCACTGGTACTCCGACGAACATGAATGGAAAGTGGCATTCATCGAAGGAAACTTTTGGTGTTCGTTCTGCAAATTTGAATGTGGATCTTCCCAAGAAATGCTACAACACATGTCCAGTTCCGACCATGGTGAAGTAGTTGCAGTTATAAATAGATCGATGCCAATCATCATTAGAAAGAAAACTGTACTGAAATGTGAAACTTGCTCTGAAATCTTTCGATATAATATAGAGTTAAAGAAGCACAGTCAGAGCACTGGACATCCTTTAGCGTACACGGCGACGGACACTTACCAAGAGCTTCACAAGTGCCAGCACTGTAACGCTAAGTTTAAGACTTCATTGACTCTTGCAGCTCATTTGAAGTCTAAACACAAACATAAGACTCACCTATGCCTGGTCTGTTCAAAGACTTTTGACTCTTCAGAAGAGGCCAAACGCCATCGCCAGTCGTCTGAGCACAGGGTTAATCGTAAGGAGATGTTGATGAAGCAAGGAGTTATCACAAAGGATCTAAGAAAGAAATGCCCATATTGTCCAGGCGATGTCACACTAAAGAATATTTTGGTTTTAAAGGACCACATCAGAGCATGCCATCCTGATGTAAAGAAAACGTGTCCAAAATGTGGTATGGAGTTCATACTTTCACAAGAAGTGACCAGTCACATAAGAGCGAAAGCCTGTAAGTTTCAAGAGCCGAGCCGTTCCTCCAACTTCTACTGGAACTGTAGCCAATGTCTCTTCACCACCAACTCCCAAGCGGAGTGCTTCTTCCACGAAGTTTTACACGACCCTCCACACACCGAAATCAAGAAAATTGGCGACGTAGAAAAAGCAGTTCAGAAATACACCTGTCCCATTTGTCCAAAGAGCTTTAGAAAGGCTTCGTTGAGACAGCATTTGAGGCAGCATACGTTCGAAAGGCCGTTCGTTTGCTCCATCTGCAAAGCTAATTTCACAAGACAGACCAGCCTGACGAATCATGTGAGGAATGATCACGGGGATGGTGCACAGAAGATGCCCAAAGCTCCAGCTGCAGGAGCAGAAGAATGGAGCTGCGATAAATGCTTGCAAGTTTTTGCTAGCAAAAGTATAAAATGTCGCCACACCTGTGGAGCTACTGACGCCAAGGTTACGAGTGTTCTGAAATGTAATGTGGAAGAATGTTCCTTCGTGGCACCCAGCGCTGATCGTCTTTCTAAACACTTAAAAAAACATGGAATCATTATTGAACACCAACGCCACAAATGTCCACAGTGTGCTTTTCGAACCAAACAGTCCAGTCATTTGAAAAGGCACTTACAGTGCCACAAAGGAAATAAACCCTACGCCTGTCCGCATTGTGATTTCACCTGTGGAAGTCTTGAAAATCTTAGAAAACATGTTCTAAGAAGTGGTCGTCATAAGGACGTATTTTTATATCTCTGCAAACATTGTGATCACAAAACTAACATGGCATCGGAGTTGCGAAAACATTTGGTCAGCGATCACAGCTGCGAATATAACGTGAAAACTGCAGCGGAGGCCGCCAAAACGCATTTGATGAATATGCCCCTGAATGTTGATGAATAA
Protein Sequence
MLSPREDDDDDTHLCIKCNTTIIGLDNYVKHRKERCAKPKTNENKPDLPPIESLDPAYSLGADVFFQSLELQSSVKKTSLSRLTPPIAISKPSIDRKSSLAIVSTSRDIPRMSPLETNLRGEDWIGGHTLRISGNEDNQTKLINAVASISGAAKKETSSSYTINYNDFKGDEESDESDVSDEDDEEDHPSGGKWKPPSNYTGGKWRPDFPEHEWDDQEHTTTWKSLLPEVDRDEDYDAPPPGHTKGKWVPGANEKTQIMQTTIQTKGSVQYWCGPCNRRLGSRAIYDKHLRSSLHLKKVLPEHELEFSGHLEPMKISGKRTTRPSKFVNDGLYSQFHRKKRQTREVKLNIKIETKKRKRRATFVHCVGCNSRVREYLMGKHLISHYHFRKAAGVTSSVYQQLILDNIEAIVHQSPFQCSPCKFYTNLLPNFMHHWYSDEHEWKVAFIEGNFWCSFCKFECGSSQEMLQHMSSSDHGEVVAVINRSMPIIIRKKTVLKCETCSEIFRYNIELKKHSQSTGHPLAYTATDTYQELHKCQHCNAKFKTSLTLAAHLKSKHKHKTHLCLVCSKTFDSSEEAKRHRQSSEHRVNRKEMLMKQGVITKDLRKKCPYCPGDVTLKNILVLKDHIRACHPDVKKTCPKCGMEFILSQEVTSHIRAKACKFQEPSRSSNFYWNCSQCLFTTNSQAECFFHEVLHDPPHTEIKKIGDVEKAVQKYTCPICPKSFRKASLRQHLRQHTFERPFVCSICKANFTRQTSLTNHVRNDHGDGAQKMPKAPAAGAEEWSCDKCLQVFASKSIKCRHTCGATDAKVTSVLKCNVEECSFVAPSADRLSKHLKKHGIIIEHQRHKCPQCAFRTKQSSHLKRHLQCHKGNKPYACPHCDFTCGSLENLRKHVLRSGRHKDVFLYLCKHCDHKTNMASELRKHLVSDHSCEYNVKTAAEAAKTHLMNMPLNVDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00927058;
90% Identity
iTF_00207433;
80% Identity
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