Lzep018148.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lasioglossum zephyrum
Gene Symbol
-
Assembly
GCA_028455615.1
Location
CM052320.1:3607553-3614463[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.2e-14 9.2e-11 41.4 0.2 9 69 255 313 249 318 0.87

Sequence Information

Coding Sequence
ATGGACGGGGCCAACGTGAATGGCGGGAACGGCGACGAGGCGCGCGAGAATCCTAACCTCGAAATCGCAGAAATGCCGGACTTACAAGAGTCGCAAATGAAAACGGATATATCCAATAAAATGGAGTGTCAGGAAGTGAACGGTGACGTTAAAGGTTCGTCGAAAAAAAGTACGACGCCGATCGCTCGAAGGAAATTACGGAAATTTAAAGCGAACTCCACTAGTACTATAGAAAGTGATACAAGTACAAAAGGACGCAAACGGAAGCTTTCAGAAACCGATGATGTTAGCTCGGAGGAGTCTACAGAGTTCAATGGATTCGATACCCAGGCAGATAACGAAATGGAACCGGGAAGTCACATTCTGAGAAAACTGATTGCTGAAGCTGAGATGGCAGAAGCTCAGTTGGCAAAACGGTTTAAATATAGTGTAAGGAAAAATTTTGATGGAAGGTACGATGAAGATTCGGATGACAATAGGATGCATAGTTACGATTCATTACATATATTAGATATAGATAAAATAAAAAAGGAAAAGGAATCTGACAAATCTGAAACAGATTCGATGGGTTTACCGAACGCTCTGGAGTCTGAAACAGACACACGAAGAACAGAAGATACATCGACCAAGTCAACAAATTCATCTGCTGCTAGTAGTCCAGCTAGAACTCCACGACCCAAAGGTCGTGGGGCTCGTGCAGCCAGTCCAGGGAGTACAGCGAAACAAAAACTGATTATTGATATGACGAACCCTGCATTCAAGGAACCATTTAAATATGGTTGGAAACGAGAGTTAGTGTTTAGAGCAAGTACCGATGTAAATCTGAAAAGAATGGCTGATATATATTATTATACACCAAAGGGAAAGAAAGTGAGAAGTTTTAGAGAAGTTGCAGAATTTCTGAATACAAAAGAGTTAACTGTTGATAATTTTACATTCTTCAAAGAACCGATCGGTATTGAAGATCCTACCAAGGAAATTATTCGAGATGCGAAAAGAATGAGAGGATCTATGGGAGCAACTCCACCTAGGAAAAGCTTTCCGCATAAGAAAAGTACACCTGGTAGAAAAGCTGCAGAACCACCGCCTACTGCTCCTGTATCTGTGCCTACAAAACCTGCTAAATCACCAAAAACTCCATCTACTGGATTTAAAGTCAAAGTGCCTGGAAAGAGAACACCTCAAATAAAAATAAAATTATCTGAAGAAAGTGAGATGCTTCCACCTCAAAGAACCACAAGCACAAGAAGGAGTCAGGCGATAGTAGAAAAACCTGTACCTCCAAAGCCTAAAAGACAACTAACGCCCAAAGTTCAAGAACCGTGCAGTATAAGATGCTCAACGAGTATGGGATTGATTCCAAGCTTACAATGTAGCGTGTGTCTCTGTTTATATCATCCTGAATGTGTTGGTGGTATGGAATTTGCGGGAAATGACGATTACGTTTGCAAGAACTGTCAGCAAGATACTAGTGAATCTCAACAATCTCAACCAAATGCGTCTATGACGCCTCCTCCATTAATACCGATTAGTATGCTAGGCACGCAAGGTGCAAAAACAAAGTACCAAGCAAACTCAACTCCTCCAAAATTACAAAGAATTCCAAAATCTGACAGTACAGATTCACAGTCTCGAAATGCTACTAAAGTTTCGAAAGCGCATCCATCGGCGTCGTATTCCCCATCGAATTCCGAGAAAAAGGAGAGCAGTTGGTATTCTCAGGCAGAAAATGAATTTTTACAAAGTCACGATGGAACCGTACCGAAACCAGCACAAAATATCGCATTGATGGGTGGCAAAAAGTACATTGTTGTGCCAAAAAATAACGCTATGGCTGTCCAGCCAGCTATAACAGTGAAACCTGATAAAATTGGTGATAAGCCTCCGATACTTCAGGATGGTTCGTTTACTGATATCTCAAACACTGCTGAAAATTCGTTAATGGGAAGGTCACATGGTCGTTCATCGACAAATTCCTCGGGCAAGGATATCGATAAGTCAAGCGACAAAAATATGTCGAAAGATATTACGCATATAGAAATGACTGCATGCTCTGTGAAGGAACAGAGAGAAGAAACATGCAATGATAGCAATAAAATAGATACAATAAATGTTAATAGATCGGAAAACGATAGATCCAATGCGAAAACAGAAGTTACAGAACGAGCCGAGAAATCAGTTGCAAGTAACAAATCACTTGAGAGGACGGCGTTAGTAAATAATTCAAACACAACTAGTACAAATAACGATAAAGTCGATTCACGACAGTCAATCACAAGTAGTTCGGGTACTATTAAAATAAGTAGCAAAATAAAGCAAACTCaacaggaaacagaagaagatgaagaagaacatcagcaacaacagcaacaacaccatcagcatcactaccaacaacatcaccaacaaccgcaacaTTTTATGGATTCGGTCTGTGCTGGATATCATGCCTTGCTACGTATATTCCAATACCTTAAAGTTCAAGAATTGCTTCGAGCGGCTAGGGTGTGCAACATGTGGAGGGACTTGGCCGCACATCCTTCTTTGTGGAAAACTGTGAGAATGAAAAATAGTCAGGTTACGGACTGGCATGGTTTAGCGGATACGTTACAAAGGCGTGGTACTCAACACTTAGATCTCCGAAAAATGCTTGTTGCGGGGGAATGCGATGACATTTGGAAAAAGTTCTTAGTAGTCATACCACGTGTCACTAGTCTCGTCAAGCTAGAGTTGTGCAGATGCCCTGTAATGGTAGTGGAAGAAGTAATAAGCAGTTGTCCTCAGTTAGAGGTATTGAGTGCAATGTCAATAAGATGCGACTCCTTGAACTTAGAATCGGTTGGAAATCTGAAACGCTGTCAAGAATTGAGGCTGAAAGCAATAAGCGGAATGTCTCTGCAAGTAGATCTCACGCCTTTACAAGAATTAACGCATTTATCGCAACTTAGTTTAACATCTGTTAAGGAACTTGGAAAGAAGAGAATCGACGTCATACAAAATCTAGCAAATTTGGAGACACTGGAATTAGGAGAATGTTCCGATTTTCCAGATAAATTTGGTACCACCGTTTTGATAAAACTGCAGAAATTAGAGCGTCTGAGGCTCGAGAAAGGCCAAGGCTCCTGTTGCACGTTCGATATTTTGGAGGGTTTGTCGAAATTGCAAAATCTAATGCAAATGGAGTTGGTCAATTTCGATGTGAAGAACGGCTTCGACAAATATCTTGCGAATTGTAAAAATATTAAGAGGCTGTTAATTATACCAACTTACATATCCCAGTCGGCAACGTCTAACAACATGGTGCTTGGCGGTGTTACCGAGTTGTCGAGTAATTTGACACACTTTGTTTGGGGTGTTACACTTGAGTTACTTAGGGTGACAGAATTATTCGTCGATCAATGTAATTTAATGAATAACCAAGTCACTGGCGACTCGATACCAATTCTCAAGCCAGTACCTTATTTGAAATTAATCAAAGATGTTGAAGATGAAAATGACAATCAAAAAGATGACGATAAACAACCAAACTTAACAAATCCTCAAGTGGATATATTGCCGTTGCCTCAACTTCAAAAACTGTTACTAACGGCATTGCCCAGGACCCGTGTTAAAATCTTAAAAATTCCTTTTCATGCGACGTGGCGGCAGAGCATTTCAGATACTGCTACGCAATAG
Protein Sequence
MDGANVNGGNGDEARENPNLEIAEMPDLQESQMKTDISNKMECQEVNGDVKGSSKKSTTPIARRKLRKFKANSTSTIESDTSTKGRKRKLSETDDVSSEESTEFNGFDTQADNEMEPGSHILRKLIAEAEMAEAQLAKRFKYSVRKNFDGRYDEDSDDNRMHSYDSLHILDIDKIKKEKESDKSETDSMGLPNALESETDTRRTEDTSTKSTNSSAASSPARTPRPKGRGARAASPGSTAKQKLIIDMTNPAFKEPFKYGWKRELVFRASTDVNLKRMADIYYYTPKGKKVRSFREVAEFLNTKELTVDNFTFFKEPIGIEDPTKEIIRDAKRMRGSMGATPPRKSFPHKKSTPGRKAAEPPPTAPVSVPTKPAKSPKTPSTGFKVKVPGKRTPQIKIKLSEESEMLPPQRTTSTRRSQAIVEKPVPPKPKRQLTPKVQEPCSIRCSTSMGLIPSLQCSVCLCLYHPECVGGMEFAGNDDYVCKNCQQDTSESQQSQPNASMTPPPLIPISMLGTQGAKTKYQANSTPPKLQRIPKSDSTDSQSRNATKVSKAHPSASYSPSNSEKKESSWYSQAENEFLQSHDGTVPKPAQNIALMGGKKYIVVPKNNAMAVQPAITVKPDKIGDKPPILQDGSFTDISNTAENSLMGRSHGRSSTNSSGKDIDKSSDKNMSKDITHIEMTACSVKEQREETCNDSNKIDTINVNRSENDRSNAKTEVTERAEKSVASNKSLERTALVNNSNTTSTNNDKVDSRQSITSSSGTIKISSKIKQTQQETEEDEEEHQQQQQQHHQHHYQQHHQQPQHFMDSVCAGYHALLRIFQYLKVQELLRAARVCNMWRDLAAHPSLWKTVRMKNSQVTDWHGLADTLQRRGTQHLDLRKMLVAGECDDIWKKFLVVIPRVTSLVKLELCRCPVMVVEEVISSCPQLEVLSAMSIRCDSLNLESVGNLKRCQELRLKAISGMSLQVDLTPLQELTHLSQLSLTSVKELGKKRIDVIQNLANLETLELGECSDFPDKFGTTVLIKLQKLERLRLEKGQGSCCTFDILEGLSKLQNLMQMELVNFDVKNGFDKYLANCKNIKRLLIIPTYISQSATSNNMVLGGVTELSSNLTHFVWGVTLELLRVTELFVDQCNLMNNQVTGDSIPILKPVPYLKLIKDVEDENDNQKDDDKQPNLTNPQVDILPLPQLQKLLLTALPRTRVKILKIPFHATWRQSISDTATQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00862564; iTF_00863271; iTF_00860392; iTF_00024619; iTF_01071023; iTF_00861876; iTF_00861141; iTF_00866009; iTF_00763229; iTF_00762552; iTF_00864638; iTF_00865320; iTF_00863954; iTF_00966030; iTF_00183948; iTF_00183286;
90% Identity
iTF_00763229;
80% Identity
-