Basic Information

Insect: Lasioglossum leucozonium
Gene Symbol: -
Assembly: GCA_028454225.1
Location: CM052205.1:9525411-9532240[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.9e-14 8.8e-11 41.3 0.2 10 69 256 313 250 318 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.9e-14	8.8e-11	41.3	0.2	10	69	256	313	250	318	0.88

Sequence Information

Coding Sequence: ATGGACGGGGCCAACGTGAATGGCGGGAACGGCGACGAGGCGCGCGAGAATCCTAACCTAGAAATCGCTGAAATGCCGGAGCTAGAGGAGACGCAAATTAAAATGGATATATCCATGAAAATGGAATGTCAGGAAGTGAACGGCGACCTCAAAGCATCGCCGAAGAAGAGTCCGACACCAGCCGTTAGAAGAAAATTACGGAAATTTAAAGCCAATTCGACTAGTACTATAGAAAGTGATACAAGTACAAAAGGACGCAAGCGGAAGCTTTCGGAAACCGATGATGTTAGTTCCGAGGAGTCTACGGAATTCAATGGATTCGATACCCAGGGAGATAACGAAATGGAACCAGGAAGTCACATTTTGAGAAAATTGATTGCTGAAGCTGAGATGGCGGAAGCTCAATTGGCAAAACGGTTTAAATATAGTGTAAAGAAAAATTTTGATGGAAGGTATGATGAAGACTCGGATGACAATAGGATGCATAGTTATGATTCGTTACATATATTAGATATAGATAAAATAAAAAAGGAAAAAGAATCTGATAAATCTGAAACAGATTCAATTGGTTTACCAAATACTTTGGAGTCTGAAACAGATACACGAAGAACAGAAGATACATCAACCAAGTCAACAAATTCATCTGCTGCTAGTAGTCCTGCTAGAACTCCACGATCTAAAGGTCGTACGGCTCGTGCAGCCAGTCCGGGAAGTACAGCAAAACAAAAAATGATTGTTGATATGTCGAACCCTGCATTCAAGGAACCTTTTAAATATGGTTGGAAACGAGAATTAGTGTTTAGAGCAAGTACAGATGTAAATCTTAAAAGAATGGCTGATATATATTATTATACACCAAAGGGAAAGAAAGTGAGAAGTTTTAGGGAAGTTGCAGAATTTCTTAATACAAAAGAGTTAACTGTTGATAATTTTACGTTCTTCAAAGAACCAATTGGTATCGAAGATCCTACCAAGGAAATTATTCGGGATGCGAAAAGAATGAGAGGATCTATGGGAACAACCCCACCCAGGAAAAGCTTTCCACATAAGAAAAATACACCTGGTAGAAGAGCTGCAGAACCACCGCCTACTACTCCTGTATCTGTACCTACAAAATCTGCTAAATCACCAAAAACTCCATCTACTGGATTTAAAGTCAAAGGGCCTGGAAAGAGAACTCCTCAAATAACAGAAATAAAATTATCGGAAGAAAGTGAGATGCTTCCACCTCAAAGAACCACAAGCACAAGAAGGAGTCAGCCGATAGTAGAAAAACCTCTACCTCCAAAGCCTAAAAGACAACTAACGCCCAAAGTTCAAGAACCATGCAGTATAAGATGCTCAACGAGTATGGGATTGATACCAAGCTTACAATGTAGCGTGTGTCTCTGTTTATATCATCCTGAATGTGTTGGTGGTATGGAATTTGCTGGAAGTGACGATTACGTTTGCAAGAACTGTCAGCAAGATACTAGTGAATCTCAACAATCTCAAACAAATGCGTCTATGACACCTCCTCCATTAATACCGATTAGTATGCTAGGCACACAAGGTGCAAAAACAAAGTATCAAGCAAACTCAACTCCTCCAAAATTACAAAGAATTCCAAAATCTGATAGTACAGATTCACAGTCTCGGAATGCTACTAAAGTTTCGAAAGCGCATCCTTCGGCATCGTATTCCCCATCAAATTCCGAGAAAAAAGAGAGCAGTTGGTATTCTCAAGCAGAAAATGAATTTTTGCAAAGTCACGATGGAACTGTACCAAAACCAGCTCAAAATATCGCATTGATGGGTGGCAAAAAGTACATTGTTGTGCCAAAAAATAATGCTATGGCTGTCCAGCCAGCTATAACAGTGAAACCTGATAAAATTGGTGATAAGCCTCCGATACTTCAGGATGGCAAGGATGTCGATAAGTCAAGTGACAGAAATATGTCCAAAGATATTACACATACGGAAATTACTGCATGCTCTGTGGAGGAACAAAGAGAAGAAACGTGCAATAACAGCAATGAGATAGATACAGTAACTGTTAATAGATCAGAAAACGATAGATCTAATGCAAAAATGGAACTAACAGAACGAGCCGAGAAATCAGTTGCAAGTAACAAATCACTTGAGAGGACGACGTTAGTAAATAATTCAAACACGACTAGTACAAATAACGATAAAGTCGATTCACGACAGTCAATCACAAGTAGTTTGGGTACTATTAAAATAAGTAGCAAAATCAAGCAAACTCAACAGGAAACAGAAGAAGAAGAAGAAGAACATCCGCAACAACAACAACACCACCACCAACAGCATCACCAACAACCACAACATTTTATGGATTCAGTCTGTGCTGGATATCATGCCTTGCTACGTATATTCCAATACCTTAAAGTTCAAGAATTGCTTCGAGCGGCTAGGGTGTGCAACATGTGGAGGGACTTGGCCGCACATCCTTCTTTATGGAAAACTGTGAGAATGAAAAATAGTCAGGTTACGGACTGGGATGGTTTAGCGGATACGTTACAAAGGCGTGGTACTCAACACTTAGATCTCCGAAAAATGCTTGTGGCGGGTGAATGTGATGACATTTGGAAAAAGTTCTTGATAGTCATACCACGTGTCACTAGTCTTGTCAAGCTAGAGTTGTGCAGATGCCCTGTAATGGTCGTGGAAGAAGTTATAAGCAGTTGTCCTCAGCTAGAGGTATTGAGTGCAATGTCAATAAAATGCGATACCTTGAATTTGGAATCGGTTGGAAACCTGAAACGCTGTCAAGAATTGAGGCTGAAAGCAATAAGCGGAATGTCTCTGCAAGTAGATCTCACGCCTTTACAAGAATTAACGCATTTATCGCAACTTAGTTTAACATCCGTTAAGGAACTTGGAAAGAAGAGGATCGACGTCATACAAAATTTAGCAAATTTGGAGACACTGGAATTAGGAGAATGTTCTGATTTTCCAGACAAATTTGGTACTACCGTTTTGATAAAACTGCAGAAATTAGAGCGCTTAAGGCTCGAAAAAGGTCAAGGCTCGTGTTGCACATTTGATATTTTGGAGGGTTTGTCGAAACTGCAAAATTTAATGCAAATGGAGTTGGTCAATTTCGATGTGAAAAATGGCTTCGACAAATATCTTGCAAATTGTAAAAATATTAAGAGGCTGTTAATTATACCAACTTACATATCCCAGTCAGCAACGTCTAACAACATGGTGCTTGGCGGTGTTACCGAATTGTCGAGTAATTTGACACACTTTGTTTGGGGCGTTACACTTGAGTTACTTAGGGTTACAGAATTATTTGTCGATCAATGTAATTTAATGAACAACCAAGTCACTGGTGACTCGATACCAATTCTCAAGCCAGTACCTTGTTTAAAATTAATCAAAGATGTTGAAGATGAAAATGACAATCAAAAAGATGATGATAAACAACCAAACTTAACAAATCCTCAAGTGGATATATTACCGTTGCCTCAACTTCAAAAACTGTTACTAACGGCATTGCCCAGGACACGTGTTAAAATCTTAAAGATTCCTTTCCATGCGACGTGGCGGCAAAGCATTTCAGATACTGCTACACAATAG
Protein Sequence: MDGANVNGGNGDEARENPNLEIAEMPELEETQIKMDISMKMECQEVNGDLKASPKKSPTPAVRRKLRKFKANSTSTIESDTSTKGRKRKLSETDDVSSEESTEFNGFDTQGDNEMEPGSHILRKLIAEAEMAEAQLAKRFKYSVKKNFDGRYDEDSDDNRMHSYDSLHILDIDKIKKEKESDKSETDSIGLPNTLESETDTRRTEDTSTKSTNSSAASSPARTPRSKGRTARAASPGSTAKQKMIVDMSNPAFKEPFKYGWKRELVFRASTDVNLKRMADIYYYTPKGKKVRSFREVAEFLNTKELTVDNFTFFKEPIGIEDPTKEIIRDAKRMRGSMGTTPPRKSFPHKKNTPGRRAAEPPPTTPVSVPTKSAKSPKTPSTGFKVKGPGKRTPQITEIKLSEESEMLPPQRTTSTRRSQPIVEKPLPPKPKRQLTPKVQEPCSIRCSTSMGLIPSLQCSVCLCLYHPECVGGMEFAGSDDYVCKNCQQDTSESQQSQTNASMTPPPLIPISMLGTQGAKTKYQANSTPPKLQRIPKSDSTDSQSRNATKVSKAHPSASYSPSNSEKKESSWYSQAENEFLQSHDGTVPKPAQNIALMGGKKYIVVPKNNAMAVQPAITVKPDKIGDKPPILQDGKDVDKSSDRNMSKDITHTEITACSVEEQREETCNNSNEIDTVTVNRSENDRSNAKMELTERAEKSVASNKSLERTTLVNNSNTTSTNNDKVDSRQSITSSLGTIKISSKIKQTQQETEEEEEEHPQQQQHHHQQHHQQPQHFMDSVCAGYHALLRIFQYLKVQELLRAARVCNMWRDLAAHPSLWKTVRMKNSQVTDWDGLADTLQRRGTQHLDLRKMLVAGECDDIWKKFLIVIPRVTSLVKLELCRCPVMVVEEVISSCPQLEVLSAMSIKCDTLNLESVGNLKRCQELRLKAISGMSLQVDLTPLQELTHLSQLSLTSVKELGKKRIDVIQNLANLETLELGECSDFPDKFGTTVLIKLQKLERLRLEKGQGSCCTFDILEGLSKLQNLMQMELVNFDVKNGFDKYLANCKNIKRLLIIPTYISQSATSNNMVLGGVTELSSNLTHFVWGVTLELLRVTELFVDQCNLMNNQVTGDSIPILKPVPCLKLIKDVEDENDNQKDDDKQPNLTNPQVDILPLPQLQKLLLTALPRTRVKILKIPFHATWRQSISDTATQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00866703;
90% Identity: iTF_00763229;
80% Identity: -