Basic Information

Gene Symbol
ham
Assembly
GCA_028829205.1
Location
JAPOND010000079.1:573635-602389[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.12 9.9 7.5 0.0 2 23 295 317 295 317 0.93
2 9 0.00064 0.055 14.6 1.5 1 23 324 347 324 347 0.93
3 9 2.1e-08 1.8e-06 28.7 0.1 1 23 353 376 353 376 0.96
4 9 1.8e-06 0.00016 22.7 1.7 1 23 382 404 382 404 0.95
5 9 4.5e-05 0.0039 18.3 5.0 1 23 410 432 410 432 0.99
6 9 0.0012 0.099 13.8 0.9 3 21 441 459 441 460 0.96
7 9 1.5e-08 1.3e-06 29.2 0.7 1 23 862 884 862 884 0.98
8 9 5.6e-07 4.8e-05 24.3 1.7 1 23 890 913 890 913 0.97
9 9 4.1e-05 0.0035 18.4 4.4 1 23 919 941 919 941 0.98

Sequence Information

Coding Sequence
ATGAGAGAGAGGGGTGCGGTACAAAGACAAGGGGTGTGTGAGGGGGTGTGGGGTGAGGAGGGGGTGGGGGGCGCGTCCCGGGCGAGGGTATGTCGGGATTCTAGGGATGAGCTCTCTCCTCTCGTTACTCTGAGACCGTTCGTCGCGGCCGTCGCACATCCGCAGACGACTCTATCGCGCTCTATCACACCGGCTGACAGCCAAGGGTCCGGAAGTCCTCCACCAAGTCCAACCGATTCAGGAACATCAGAATCAGCGCCCACCCTAGTCCACATCAAGCAAGAAAACATGGCGCCAGGAACAGACATGAAGGAATATTACAGTGCTTTGGACTTTGGTCTCCAAGAATCCTATCTTTCAAACTACGACTACAGCCAAAAATATTTCGCCAGAACTCTTGATCTCCCGAACGACAGGTTCCTGGACCAGACCAAGACTGCTGAGGATGACAGTGATTTTTTGGCTGATTTGGAGAAGTCAGAATTAAATTTACCAAGAGaattgaaagttttaaaatctGGTGGAATCGTCGCCAGAACTAACATTCCTGCTGGAACTAAATATGGACCTTTCAATGGCAAGTGGGAGgtttttgGCAAGAACGGAGTGCGGTCTTGGCTGGATGGAACCACAGAGAAGTCCAATTGGTTTAAGCTGGTTCGCTGCAGCACCTCACCGGATGAAGTCAACCTACAACATGAGAAGTTTGCAGGACAGATCTGGTACAAGGTAACGCGCGAAGTCAGCTCGGGGCAGGAGTTACTGGTGGCTCCCTGGACGTCGCTGCCGCTCCAGGACTCTCTCACAGCTACTGgtAGAGAGAGTGCCACCAGTCACTCTCATCCCCAGCAAGAAGAAGAAGATAGAGAGGACACGAAGCCGCGTTGCTTCTTCTGCGAGGAGCCCTTTCCTAATATAGATGCACTTGATCGCCACTTGATCCAAGCGCATGCACAGCCAGCATCAGCATATCACTGCGAATACTGCAACAGAGCATATAGCTATCGTGCGCTCCTGTTGAGGCATCGAGCTTTAAGCCATACTGATATTAAGAAATATCCCTGCGAGAATTGCCCCAAGGTATTTACCGATCCTTCCAACCTTCAGCGCCACATCCGCGCTCAGCACGTCGGCGCGCGCAGCCACGCTTGCCCCGAGTGTGGTAAAACCTTCGCGACGAGCTCGGGACTCAAGCAGCACACGCATATCCACTCCAGCGTCAAGCCTTTCCAGTGCGAAGTTTGCTTCAAGGCGTACACCCAGTTTTCGAATTTGTGTCGACACAAACGAATGCACATTGCTTGCAAAACTTTGTCTGGGTGTAGGAAATGCGGACAATCTTTTTCCACTTACGCATCTCTTGCTAAGCACAAGAGATTTTGTGAAACCGCTACCACTCCAAGCGTCAATCTTCGAGGTCAGATTGGACAAAGCTTACAACAGATACCACCGCTACCTAACACTATGAATAATCCAAACAATACCAATCCATTCCCCATGTATAGGGGACCAGCACTTCCGTTACCATACAATACGTTCGCACATTACCCAGCTTTTATCTCTGCAGCTGCAGCCGCTGCTTGCCCACCAGATTTTTTAAGCCCTCTTCTTTTCAACGTACAAGGCGCGAGATTGGCTATGGAACATGACTTGGCACTTAATGCTAGTTTAATGGCAAAACAACAACAAGAAGGAAGAAGGTCGGTTAAAAGAGAGACAGAGAGCATAGATAGTTCCACTTCTGTAGAATTATTGAATAAAGGAAAAGATATCGTTTGTGATGATAAAGAAATGGATGTAGATAGAGTTACACCAAAACCTCAGAATCATTACGTTAAACAATCACCACCGTCGGCTGAAGAGGCTACGTCAAAACAACGTCCATCGCCAGTAATGCCAATGTCAACTTCGGTAGGTCCCTTTGATTTTTCAAGAAATGAAATAAAGCATAACTCGATATATGATTTTCCGATGAAGGtaaataataacgaaaaaatCGAAAATAAGTCAGTATCACCCCAGCCCAAAGATTTGACAAAGAACATCACTGATGATATTGATAAACAATCTAGATATTCTAACATGGAGGAAGATAAACCAAAAGAACATAATGACCAACCACTTGATTTATCGGTTTCCCGAAAACCACGTGAGAAGGAATCAGACTTTGAAAATGATGATAAGTCTTTCCGTAATTCTTCAATCAAATCCTATTCGCCACCCGAAAGTCCAATTGATAGAGAAAACAAGACTCCTGAAAATGAGACAACGGATGTTGATGTAGAGGCTGTTGAACCAAAACGAGAAGAATCCCCTGTTTCAATGATATCTCCTCCTTTAGCGTTTCCAATGGCCGTTCATGCTCAGCACAACAACAGTCTTATGAACGCAATGTACCCGCCACGTTTTTCAAGATTTCACTCAGCTTCAGACTCTATACTGAATTCACAACACTCACCCTATGTTCCTAGCCCGTTTAATTTTTTATCGCCACTTCTGGGAACTGATGGCCCTGAAAGGCAGTCAAGTGCTTACGCCAAATTTCGTGAACTGAGCGCTGGTACTGGTAAACTAAGAGATCGTTACGCTTGCAAATTTTGTGGAAAAGTATTTCCACGTAGTGCTAACTTGACACGACATCTTCGCACACACACCGGCGAACAGCCCTACAAGTGCAAGTACTGCGAGCGCTCATTCTCCATATCGTCTAATTTACAGCGGCATGTAAGAAATATTCACAACAAGGAACGGCCGTTTAGGTGTCAGTTATGCGACAGGTGTTTCGGGCAGCAAACTAATTTAGATCGGCATTTGAAGAAACACGAAGCTGAAGGTGGAGATTCACCGAGTTCTGGGGATACCGAACATGACGCGTGTTTTGATGACATTCGTTCCTTTATGGGCAAGGTGACATGCTCTCCCAGCGAGTGCTCTCCTTCTACTAACTCGCCGCACTCCTCTCATCACGCACACCCTCCGCATCGTCCTTCTGCTCTTTCTATCTCCACCTAG
Protein Sequence
MRERGAVQRQGVCEGVWGEEGVGGASRARVCRDSRDELSPLVTLRPFVAAVAHPQTTLSRSITPADSQGSGSPPPSPTDSGTSESAPTLVHIKQENMAPGTDMKEYYSALDFGLQESYLSNYDYSQKYFARTLDLPNDRFLDQTKTAEDDSDFLADLEKSELNLPRELKVLKSGGIVARTNIPAGTKYGPFNGKWEVFGKNGVRSWLDGTTEKSNWFKLVRCSTSPDEVNLQHEKFAGQIWYKVTREVSSGQELLVAPWTSLPLQDSLTATGRESATSHSHPQQEEEDREDTKPRCFFCEEPFPNIDALDRHLIQAHAQPASAYHCEYCNRAYSYRALLLRHRALSHTDIKKYPCENCPKVFTDPSNLQRHIRAQHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHIACKTLSGCRKCGQSFSTYASLAKHKRFCETATTPSVNLRGQIGQSLQQIPPLPNTMNNPNNTNPFPMYRGPALPLPYNTFAHYPAFISAAAAAACPPDFLSPLLFNVQGARLAMEHDLALNASLMAKQQQEGRRSVKRETESIDSSTSVELLNKGKDIVCDDKEMDVDRVTPKPQNHYVKQSPPSAEEATSKQRPSPVMPMSTSVGPFDFSRNEIKHNSIYDFPMKVNNNEKIENKSVSPQPKDLTKNITDDIDKQSRYSNMEEDKPKEHNDQPLDLSVSRKPREKESDFENDDKSFRNSSIKSYSPPESPIDRENKTPENETTDVDVEAVEPKREESPVSMISPPLAFPMAVHAQHNNSLMNAMYPPRFSRFHSASDSILNSQHSPYVPSPFNFLSPLLGTDGPERQSSAYAKFRELSAGTGKLRDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFRCQLCDRCFGQQTNLDRHLKKHEAEGGDSPSSGDTEHDACFDDIRSFMGKVTCSPSECSPSTNSPHSSHHAHPPHRPSALSIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2