Hano012601.1
Basic Information
- Insect
- Himalopsyche anomala
- Gene Symbol
- MBD2
- Assembly
- GCA_031772345.1
- Location
- CM062834.1:21456846-21471660[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.8e-27 1.2e-23 82.7 0.1 2 73 6 72 5 75 0.94 2 2 0.0011 4.9 7.1 0.0 28 72 93 145 78 149 0.77
Sequence Information
- Coding Sequence
- ATGAGTGTTTCTAtagagaagaaaaaaacagaCTGTGCCGCCTTGCCAAAAGGATGGCAGCGAGAAGAGGTGTTGAGAAAGTCAGGATTATCCGCAGGAAAAGttgatgtatattattacaGTCCGTCCGGGAAGAAGTTCCGCAGTAAGCCGCAGCTGGCGCGCTACCTGGGGGAGAGTCTGGACTTGGCCTGCTTTGACTTTCAACAGGGCCGCCTTAATACTCTGTTGCTACGCAAAAGGAAGCCGCGCGGCACGCAATTCGATTACAGCCGAGGCGTGAGATCGGACGCTTCGCTGGTTCCCCCCATTCGGCAGACCGCATCCATTTTTAAACAGCCTGTCACCGTTCACAAGAGTCAAGAGAGCAAGGTTAAAACTGACTTCAAGCACGGTCCACAGGATAAGCCCAAGCAGCTATTCTGGGAGAAGAGACTTGAGGGTCTGAGCGCTTGCGACTCCTGGGGAGTTCTAGGAGGAGCATCGCTTCCCAGAGGTATCAAATGTATGGGACCGCACATCAATGATGCCACCACGATACAAGCTCTCGCCACAGCTCTGCATGTCACCCCGCAACCTGTCACAGGCCAAACCGGATCAAAAACGGCGATTGCTCAAAACCCCGGAGTGTTCCTGAACCCTGAGCAGCCGCTAGTGCAGGCGGTCACGGTTGCCGAAGAAGACATCAGACGGCAGGAGGAGAGAGTCAACCGGGCCAGGAGGAAATTGCAAGATGCCCTCGATTGCGGCGGAGTCGGAGTGGATCACTTCGATTCGATCGACCCAATCGAGCGCTACTCTTTCTACAATTGA
- Protein Sequence
- MSVSIEKKKTDCAALPKGWQREEVLRKSGLSAGKVDVYYYSPSGKKFRSKPQLARYLGESLDLACFDFQQGRLNTLLLRKRKPRGTQFDYSRGVRSDASLVPPIRQTASIFKQPVTVHKSQESKVKTDFKHGPQDKPKQLFWEKRLEGLSACDSWGVLGGASLPRGIKCMGPHINDATTIQALATALHVTPQPVTGQTGSKTAIAQNPGVFLNPEQPLVQAVTVAEEDIRRQEERVNRARRKLQDALDCGGVGVDHFDSIDPIERYSFYN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00023790;
- 90% Identity
- iTF_01218336;
- 80% Identity
- iTF_00800194;