Basic Information

Insect: Hemithea aestivaria
Gene Symbol: SGF1
Assembly: GCA_947507615.1
Location: OX382344.1:5369753-5370784[-]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.2e-40 2.6e-37 127.4 0.0 2 88 110 195 109 195 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.2e-40	2.6e-37	127.4	0.0	2	88	110	195	109	195	0.98

Sequence Information

Coding Sequence: ATGATCTCGCAGAAGCTCTCGTACGGCGACGTGCCGACGTCCGCGTCGCTGTCTTCGCTGTCGCCGGGCCTCGCGCCGCCGTACGTCAACGGCATGGGGTGCATGCCGGCGCAGCCCTACCCGAACCTGTACTCCAACAACATGGTGGCCGGCGGCTCGTGCATGGGCTCGCCCGGCGTCGGCTACTCGCCGCCCAGCACCATGGCGTCCTGCATGGGCGGCGGCGGCTACGGAGCCCTGCCGCGCGACCAGGAGGCCGCCTCGCCCACCTCGGCGCTCCAGCGCGCGCGCAACGACAAGACCTACCGCCGCTCCTACACGCACGCGAAGCCTCCCTACTCGTACATCTCGCTGATCACGATGGCCATCCAGAACAACCCGTCGCGCATGCTCACACTCTCCGAGATCTACCAGTTCATCATGGACCTGTTCCCGTTCTACAGACAGAACCAGCAGCGGTGGCAGAACTCGATCCGACACTCGCTCTCGTTCAACGACTGCTTCGTGAAGGTGCCGCGCACCCCCGACAAGCCCGGCAAGGGATCGTTCTGGACTCTGCACCCGGACAGCGGGAACATGTTCGAGAACGGGTGCTTCCTGCGGAGACAGAAGCGGTTCAAGGACGAGAAGAAGGAGACGATGCGGCAGGCGCAGAAGGCGCAGCACGGGCACGGGCACCACGGCGGGCACGACAAGCGCGAGCACGCGCACGAGAAGGGCGGCGGCGGCGCGGGCGAGGAGAAGGAGATGCGAGACGAGTTGCTCGCGCAGCTGCACGCGGCGCCCGAGCTGTGCCTGCCCGAGCACACGCCGCTGGCGCTCGAGCACTACGCGCAGCTGAAGCAGGAGCCGCCGGGGTACGCGCCCGCGCAGCACCCCTTCAGCATCACGCGGCTGCTGCCCGGCGCCGACACCAAGGCCGACCTCAAGATGTACGACGTCAACTACGGGTACGGCCACTCGCCGGCGGACAACTACTACCAGTCGCCGCTGTACCACCACCACCACGCGCACGCGCAGCCTCCCTTGTGA
Protein Sequence: MISQKLSYGDVPTSASLSSLSPGLAPPYVNGMGCMPAQPYPNLYSNNMVAGGSCMGSPGVGYSPPSTMASCMGGGGYGALPRDQEAASPTSALQRARNDKTYRRSYTHAKPPYSYISLITMAIQNNPSRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKVPRTPDKPGKGSFWTLHPDSGNMFENGCFLRRQKRFKDEKKETMRQAQKAQHGHGHHGGHDKREHAHEKGGGGAGEEKEMRDELLAQLHAAPELCLPEHTPLALEHYAQLKQEPPGYAPAQHPFSITRLLPGADTKADLKMYDVNYGYGHSPADNYYQSPLYHHHHAHAQPPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00818169;
90% Identity: iTF_00790052; iTF_00250270; iTF_00355937; iTF_00926401; iTF_01134594; iTF_00462181; iTF_00342022; iTF_01135563; iTF_00325178; iTF_00021148; iTF_00323300; iTF_00858356; iTF_00699908; iTF_01083108; iTF_00430428; iTF_00164132; iTF_01178214; iTF_01140041; iTF_01205513; iTF_01202282; iTF_00405739; iTF_01204683; iTF_01203853; iTF_01147919; iTF_01203055; iTF_00934546; iTF_00878678; iTF_00403576; iTF_01217304; iTF_01247896; iTF_00288667; iTF_01206364; iTF_00933534; iTF_00744415; iTF_01161124; iTF_01362308; iTF_00072058; iTF_00017987; iTF_00383428; iTF_00449929; iTF_00049708; iTF_01342028; iTF_01361389; iTF_01362902; iTF_01424855; iTF_00017152; iTF_01545572; iTF_01542768; iTF_01544691; iTF_01546454; iTF_01543712; iTF_01560941; iTF_00806502; iTF_00967857; iTF_00698986; iTF_00705795; iTF_00801610; iTF_01091503; iTF_00204939; iTF_00780075; iTF_00775073; iTF_00781634; iTF_01062562; iTF_00420355; iTF_00777251; iTF_01532836; iTF_01063557; iTF_00711622; iTF_00011751; iTF_00042439; iTF_00421159; iTF_00012744; iTF_00421160; iTF_00419593; iTF_00621033; iTF_00778601; iTF_00959978; iTF_00776587; iTF_01534603; iTF_00446924; iTF_00194989; iTF_00709998; iTF_01533742; iTF_00953328; iTF_01220464; iTF_00039601; iTF_00300977; iTF_00720017; iTF_00780849; iTF_01084945; iTF_00774322; iTF_01181714; iTF_00041587; iTF_00782451; iTF_00928467; iTF_00958515; iTF_01302099; iTF_00301908; iTF_00444917; iTF_00072534; iTF_00651542; iTF_00959222; iTF_00685239; iTF_00775863; iTF_00777815; iTF_00144376; iTF_01061689; iTF_00040602; iTF_00640090; iTF_01064442; iTF_01084058; iTF_00043291; iTF_00146203; iTF_01531772; iTF_00445917; iTF_00457056; iTF_00457824; iTF_00779328; iTF_00706753; iTF_01501896; iTF_00157010; iTF_00823734; iTF_01197531; iTF_01316129; iTF_01386529; iTF_01385515; iTF_01388276; iTF_01340959; iTF_01387423; iTF_00468002; iTF_00467267; iTF_00723779; iTF_00722850; iTF_00247852; iTF_00246994; iTF_00159639; iTF_01279074; iTF_00075268; iTF_00076262; iTF_00074288; iTF_01282033; iTF_01281116; iTF_00771683; iTF_00850402; iTF_00851526; iTF_00951601; iTF_00299958; iTF_00973529; iTF_00932227; iTF_00677349; iTF_00896582; iTF_01034342; iTF_00461364; iTF_00673302; iTF_01033530; iTF_00842459; iTF_01073414; iTF_00621830; iTF_01506150; iTF_01507876; iTF_00674120; iTF_00822696; iTF_00832712; iTF_00186953; iTF_00687721; iTF_00960745; iTF_01285354; iTF_01358698; iTF_00859269; iTF_01547338; iTF_00428811; iTF_00427906; iTF_00273420; iTF_00290476; iTF_00827788; iTF_00213229; iTF_01359526; iTF_00236458; iTF_00212236; iTF_01152854; iTF_00025085; iTF_00287869; iTF_00441293; iTF_00796333; iTF_01075181; iTF_00843310; iTF_00985806; iTF_01506977; iTF_00824516; iTF_00984839; iTF_00695287; iTF_01029966; iTF_00171567; iTF_01230319; iTF_00808912; iTF_00818960; iTF_01179312; iTF_01180135; iTF_01312048; iTF_00113146; iTF_00112320; iTF_01317088; iTF_01425776; iTF_01437776; iTF_00786577; iTF_00925543; iTF_01078001; iTF_01429745; iTF_01438706; iTF_00077299; iTF_01569075; iTF_01018389; iTF_01017549; iTF_00150294; iTF_01439703; iTF_00406520; iTF_00407374; iTF_00795512; iTF_00931032; iTF_01079704; iTF_01078885; iTF_01145112; iTF_00708985; iTF_01443641; iTF_00341146; iTF_00345626; iTF_00358330; iTF_00357231; iTF_01124410; iTF_01125254; iTF_01173082; iTF_00751835; iTF_00819867; iTF_01025787; iTF_01029025; iTF_01027108; iTF_01028070; iTF_00888024; iTF_01030941; iTF_01151035; iTF_00063388; iTF_00282076; iTF_00280940; iTF_00418780; iTF_00667164; iTF_00905921; iTF_01076193; iTF_01360418; iTF_01487522; iTF_00783235; iTF_00147108; iTF_01166404; iTF_00834437; iTF_00637286; iTF_00787430; iTF_00907687; iTF_01491687; iTF_00374984; iTF_00007817; iTF_00038505; iTF_00120297; iTF_00889001; iTF_01526825; iTF_01092874; iTF_00784203; iTF_00809867; iTF_01246635; iTF_00071212; iTF_00124044; iTF_01525740; iTF_00726093; iTF_00326894; iTF_00736430; iTF_00908622; iTF_00924398; iTF_00036431; iTF_01192431; iTF_01259887; iTF_00037584; iTF_00274256; iTF_00636080; iTF_00794129; iTF_00785010; iTF_00821586; iTF_00122163; iTF_00176915; iTF_00906867; iTF_00121204; iTF_01093845; iTF_01339765; iTF_00123158; iTF_00373718; iTF_00404503; iTF_00869431; iTF_01221303; iTF_01338295; iTF_00237274; iTF_00745434; iTF_00172539; iTF_00185947; iTF_00363835; iTF_00622619; iTF_00757947; iTF_00448828; iTF_00425182; iTF_00830974; iTF_00837278; iTF_00185119; iTF_01151871; iTF_01332352; iTF_01279996; iTF_01440796; iTF_01502780; iTF_01503657; iTF_00347325; iTF_00408206; iTF_00364723; iTF_01071449; iTF_00942618; iTF_00835357; iTF_00836328; iTF_00947709; iTF_00431941; iTF_01080541; iTF_01435869; iTF_00026654; iTF_00027570; iTF_01489950; iTF_00235682; iTF_00000991; iTF_00000125; iTF_00277183; iTF_00647807; iTF_00353888; iTF_00352849; iTF_00785824; iTF_01010176; iTF_01172139; iTF_00317923; iTF_00702700; iTF_00703745; iTF_00954220; iTF_00634125; iTF_00635204; iTF_00697134; iTF_00895727; iTF_01193423; iTF_01182480; iTF_00661089; iTF_01170378; iTF_01219594; iTF_01529006; iTF_01509391; iTF_00376912; iTF_00266994; iTF_00909557; iTF_01528089; iTF_00662044; iTF_00856412; iTF_01428861; iTF_01207920; iTF_00124973; iTF_01451280; iTF_01452148; iTF_01453088; iTF_00825393; iTF_00826633; iTF_00044268; iTF_00205871; iTF_00142904; iTF_00354898; iTF_00648918; iTF_00649835; iTF_00874262; iTF_00875110; iTF_00875962; iTF_01138774; iTF_00197185; iTF_00971042; iTF_00166755; iTF_00770915; iTF_01139460; iTF_01082246; iTF_01148647; iTF_00970216; iTF_01149386; iTF_01144366; iTF_01140751; iTF_01142223; iTF_01142930; iTF_01141465; iTF_01147227; iTF_00114749; iTF_00180258; iTF_00249525; iTF_01402550; iTF_00686147; iTF_00737282; iTF_01099687; iTF_01171273; iTF_00361421; iTF_00662896; iTF_00810806; iTF_00119418; iTF_00632571; iTF_01335739; iTF_00638461; iTF_01115523; iTF_00994180; iTF_01416581; iTF_01495592; iTF_01494129; iTF_01496374; iTF_01494871; iTF_01129865; iTF_01154827; iTF_00840130; iTF_00255625; iTF_00642153; iTF_00922708; iTF_00256661; iTF_00204182; iTF_01158523; iTF_01156095; iTF_00913420; iTF_00390189; iTF_00666317; iTF_01119087; iTF_01118064; iTF_00111410; iTF_01116979; iTF_01415631; iTF_00006893; iTF_00155122; iTF_00156063; iTF_00206805; iTF_01176021; iTF_00855702; iTF_00818169; iTF_00055211; iTF_01463066; iTF_00761435; iTF_01436827; iTF_01209014; iTF_00207671; iTF_00208640; iTF_00704759; iTF_00700811; iTF_00321405; iTF_00887229; iTF_00033631; iTF_00032716; iTF_00698079; iTF_00696308;
80% Identity: -