Hfas005325.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hylaea fasciaria
Gene Symbol
SGF1
Assembly
GCA_905147375.1
Location
LR990210.1:3678848-3679888[-]

Transcription Factor Domain

TF Family
Fork_head
Domain
Fork_head domain
PFAM
PF00250
TF Group
Helix-turn-helix
Description
The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.8e-40 1.9e-37 127.4 0.0 2 88 112 197 111 197 0.98

Sequence Information

Coding Sequence
ATGATCTCGCAGAAGCTGTCGTACGGCGACGTGCCGACGTCCGCGTCGCTGTCCTCGCTGTCGCCGGGCCTCGCGCCGCCCTACGTCAACGGCATGGGCTGCATGCCGGCGCAGCCCTACCCGAACCTGTACTCCAACAACATGGTGGCCGGCGGCTCCTGCATGGGCTCCCCGGGCGTGGGCTACTCGCCGCCCAGCACCATGGCGTCCTGCATGGGCGGCGGCGCCGGCGTCTACGGGAGCCTGCCGCGCGACCAGGAGGCCGCTTCGCCCACCTCGGCGTTGCAACGAGCGCGTAACGACAAGACCTACCGCCGCTCCTACACGCACGCGAAGCCACCGTACTCCTACATCTCGCTCATCACGATGGCCATCCAGAACAATCCGTCGCGCATGCTCACGCTGTCTGAGATCTACCAGTTCATCATGGACCTGTTCCCGTTCTACCGGCAGAACCAGCAGCGGTGGCAGAATTCGATCCGACACTCGCTGTCGTTCAACGACTGTTTCGTGAAAGTGCCGCGCACGCCCGACAAGCCGGGGAAGGGGTCGTTCTGGACGCTGCACCCGGACAGCGGGAACATGTTCGAGAACGGCTGCTTCCTGCGGCGGCAGAAGCGGTTCAAAGATGAGAAGAAGGAAACGATCAGACAAGCGCAGAAGGCGCAGCACGGGCACGGTCACCACGGCGGCGGGCACGACAAGCGGGAGCACGCGCACGAGAAAGGCGGCGGTGGTGCGCCCGAGGAGAAAGAGATGAGAGACGAGCTCCTCGCTCAGCTGCACGCGGCGCCCGAGCTGTGCCTGCCCGAGCACACGCCGCTGGCGCTGGAGCACTACGCGCAGCTGAAGCAGGAGCCGCCAGGGTACGCGCCCGCGCAGCATCCCTTCAGCATCACACGCCTGCTGCCCGGCGCCGACACCAAGGCGGACCTCAAAATGTACGACGTCAACTACGGGTACGGCCACTCGCCAGCGGAGAACTACTACCAGTCGCCGCTGTACCACCATCACCACGCGCACGCGCAGCCGCCCTTGTGA
Protein Sequence
MISQKLSYGDVPTSASLSSLSPGLAPPYVNGMGCMPAQPYPNLYSNNMVAGGSCMGSPGVGYSPPSTMASCMGGGAGVYGSLPRDQEAASPTSALQRARNDKTYRRSYTHAKPPYSYISLITMAIQNNPSRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKVPRTPDKPGKGSFWTLHPDSGNMFENGCFLRRQKRFKDEKKETIRQAQKAQHGHGHHGGGHDKREHAHEKGGGGAPEEKEMRDELLAQLHAAPELCLPEHTPLALEHYAQLKQEPPGYAPAQHPFSITRLLPGADTKADLKMYDVNYGYGHSPAENYYQSPLYHHHHAHAQPPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00055211; iTF_01172139; iTF_01443641; iTF_01090498; iTF_01401090; iTF_01027108; iTF_01025787; iTF_01222292; iTF_00317923; iTF_00686147; iTF_00737282; iTF_01099687; iTF_01171273; iTF_00361421; iTF_00662896; iTF_00810806; iTF_00119418; iTF_00632571; iTF_01335739; iTF_00638461; iTF_01509391; iTF_00705795; iTF_00698986; iTF_00700811; iTF_01083108; iTF_00715619; iTF_00699908; iTF_01182480; iTF_00661089; iTF_01170378; iTF_01219594; iTF_00376912; iTF_00856412; iTF_01428861; iTF_00790052; iTF_00791009; iTF_01161124; iTF_01333540; iTF_01331238; iTF_01081394; iTF_00006101; iTF_01545572; iTF_01542768; iTF_01544691; iTF_01546454; iTF_01543712; iTF_00355937; iTF_00431941; iTF_00318694; iTF_00806502; iTF_01020998; iTF_00447976; iTF_00034516; iTF_00035451; iTF_00204939; iTF_00382379; iTF_01334565; iTF_00044268; iTF_00205871; iTF_00142904; iTF_00926401; iTF_00826633; iTF_00825393; iTF_00206805; iTF_00162316; iTF_01041548; iTF_00634125; iTF_00635204; iTF_00666317; iTF_01560941; iTF_00207671; iTF_00208640; iTF_01016376; iTF_00697134; iTF_01529006; iTF_00266994; iTF_01528089; iTF_00662044; iTF_01119087; iTF_01118064; iTF_00111410; iTF_01116979; iTF_00418780; iTF_01230319; iTF_01451280; iTF_01452148; iTF_01453088; iTF_00284337; iTF_00951601; iTF_00850402; iTF_00851526; iTF_00973529; iTF_00155122; iTF_01134594; iTF_00462181; iTF_00342022; iTF_01135563; iTF_00325178; iTF_00021148; iTF_00156063; iTF_01367506; iTF_00276083; iTF_00666323; iTF_00666324; iTF_00299958; iTF_00771683; iTF_00648918; iTF_01209014; iTF_01506977; iTF_00124973; iTF_00704759; iTF_00667164; iTF_00905921; iTF_01076193; iTF_00871106; iTF_01360418; iTF_01487522; iTF_00783235; iTF_00147108; iTF_01166404; iTF_00637286; iTF_00787430; iTF_00907687; iTF_01491687; iTF_00374984; iTF_00007817; iTF_00038505; iTF_00120297; iTF_00186953; iTF_00889001; iTF_01526825; iTF_00412330; iTF_01092874; iTF_00784203; iTF_00809867; iTF_01246635; iTF_00071212; iTF_00124044; iTF_01525740; iTF_00726093; iTF_00326894; iTF_00736430; iTF_00908622; iTF_00924398; iTF_00036431; iTF_01192431; iTF_01259887; iTF_00037584; iTF_00274256; iTF_00636080; iTF_00794129; iTF_00785010; iTF_00821586; iTF_00122163; iTF_00176915; iTF_00906867; iTF_00121204; iTF_01093845; iTF_01339765; iTF_00123158; iTF_00150294; iTF_00373718; iTF_00404503; iTF_00869431; iTF_01221303; iTF_01338295; iTF_00237274; iTF_00745434; iTF_00172539; iTF_00185947; iTF_00363835; iTF_00622619; iTF_00757947; iTF_00448828; iTF_00411229; iTF_00425182; iTF_00830974; iTF_00185119; iTF_01151871; iTF_01332352; iTF_01316129; iTF_01312048; iTF_00113146; iTF_00112320; iTF_01317088; iTF_00235682; iTF_00427906; iTF_00236458; iTF_00428811; iTF_01489950; iTF_00468002; iTF_00467267; iTF_00723779; iTF_00971042; iTF_00166755; iTF_01082246; iTF_00970216; iTF_00887229; iTF_01062562; iTF_01532836; iTF_01063557; iTF_00711622; iTF_00042439; iTF_01534603; iTF_00446924; iTF_01533742; iTF_00039601; iTF_00300977; iTF_01084945; iTF_00041587; iTF_00928467; iTF_00444917; iTF_00685239; iTF_01061689; iTF_00040602; iTF_01064442; iTF_01084058; iTF_00043291; iTF_01531772; iTF_00445917; iTF_00932227; iTF_00824516; iTF_00994180; iTF_01362308; iTF_00677349; iTF_01416581; iTF_01073414; iTF_00621830; iTF_01506150; iTF_01507876; iTF_00984839; iTF_00674120; iTF_00449929; iTF_01285354; iTF_01358698; iTF_00859269; iTF_00273420; iTF_00290476; iTF_00702700; iTF_00703745; iTF_00913420; iTF_00006893; iTF_00390189; iTF_00441293; iTF_00772685; iTF_00149185; iTF_00148294; iTF_00680331; iTF_00171567; iTF_00895727; iTF_00818960; iTF_01145872; iTF_01179312; iTF_01180135; iTF_01207920; iTF_01245744; iTF_01425776; iTF_00967857; iTF_01429745; iTF_00027570; iTF_01438706; iTF_01437776; iTF_00301908; iTF_00858356; iTF_00695287; iTF_01424855; iTF_00049708; iTF_01439703; iTF_00795512; iTF_00072058; iTF_00017987; iTF_00383428; iTF_01342028; iTF_01361389; iTF_01362902; iTF_00000125; iTF_00000991; iTF_00017152; iTF_00341146; iTF_00345626; iTF_01124410; iTF_01125254; iTF_01173082; iTF_00761435; iTF_00819867; iTF_01436827; iTF_00063388; iTF_00282076; iTF_00280940; iTF_01502780; iTF_01503657; iTF_00947709; iTF_00026654; iTF_00250270; iTF_00033631; iTF_00032716; iTF_01010176; iTF_00683135; iTF_00681473;
90% Identity
iTF_00791009;
80% Identity
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