Basic Information

Insect: Hemistola chrysoprasaria
Gene Symbol: slp2
Assembly: GCA_947063395.1
Location: OX346716.1:16296591-16297538[+]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.9e-42 3.7e-39 133.4 0.1 1 87 71 156 71 157 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.9e-42	3.7e-39	133.4	0.1	1	87	71	156	71	157	0.97

Sequence Information

Coding Sequence: ATGGTGAAGTTTGAAGGAGATTTCAGTATTAATTCAATACTGATGAACCACGCGACTTCCAAGCCCCCGCCGTCACCGTCGCCCTCGTCGACGGGCGCCTCGCCCTCCGAGGCCGACCTCAGCGACTCCGAGCTCGACGTCACCGGCACGGAGCCCGTCGACTGCACCAAACCGAAGGACGACGACGAACAAAAGAAGGACAAGAAACACGAAAAGCCCGCCTACAGCTATAACGCTCTCATCATGATGGCGATTCGCAACAGCCCCGAAAAAAGATTGACTCTCAACGGAATCTACGAGTACATCATGACAAACTTCCCGTACTACAGGGAGAACAGGCAGGGCTGGCAGAACTCCATCCGCCACAACCTGAGCTTGAACAAGTGCTTTGTGAAAGTGCCGCGACACTACGACGACCCGGGGAAGGGTAACTACTGGATGTTGGACGCGTCGGCCGAGGACGTGTTCATCGGCGGCACGACGGGCAAGCTGCGCCGGCGCTCCGCTCTCAACGGCCGCTCGCGCCTCGCCTGCTTCAAGCGGCCTCTGTTCCCCGGCGCGCCGCTGCTGCCCGGCGGCTCCTACCCGCCCGCCACGTACTCTCAACTGGTCGGCCTCTACTCTCAGCTGCTGTATCAGAGGTACGCGCCGATGCAAATGAAGACCCACCCGGTAGCACCGAGTGCGGTGCACCCCGCATTCCGAGGAGCCGAATCTATGCCGTATGGAAGCTTGCCGTATTCGACCGGTATGTACGAGCGGCTGCCGTCGGGTGCCTTCCTGGGTCAGGCACCGATGCTGCAGACGTCCCCTCTGATGCCGCCCTCTCCGCCGATGATGCACTCGCCTCCTACCTCCGGTGCGTCGAGCCCCGAGCTGCCCTCGCCGTCTCATCACCCGCTCTCCCCACACATCTACAAGCCCGTCACGGTTCTCACACGGCAGTGA
Protein Sequence: MVKFEGDFSINSILMNHATSKPPPSPSPSSTGASPSEADLSDSELDVTGTEPVDCTKPKDDDEQKKDKKHEKPAYSYNALIMMAIRNSPEKRLTLNGIYEYIMTNFPYYRENRQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDASAEDVFIGGTTGKLRRRSALNGRSRLACFKRPLFPGAPLLPGGSYPPATYSQLVGLYSQLLYQRYAPMQMKTHPVAPSAVHPAFRGAESMPYGSLPYSTGMYERLPSGAFLGQAPMLQTSPLMPPSPPMMHSPPTSGASSPELPSPSHHPLSPHIYKPVTVLTRQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00791004; iTF_00323297; iTF_00806498; iTF_01124407; iTF_01125251; iTF_01340955; iTF_01161122; iTF_01334562; iTF_00421156; iTF_00419590; iTF_00418777; iTF_00420352; iTF_00674116; iTF_00447972; iTF_01154823; iTF_01158520; iTF_01156092; iTF_00736427; iTF_01337580; iTF_00204179; iTF_01090494; iTF_01500910; iTF_01336632; iTF_00177884; iTF_00844124; iTF_01153661; iTF_01157473; iTF_01333536; iTF_01129862; iTF_00382375; iTF_00726089; iTF_00172535; iTF_01246631; iTF_00745431; iTF_00425178; iTF_00830970; iTF_00697131; iTF_00701762; iTF_00699905; iTF_00698983; iTF_00700809; iTF_00702697; iTF_00696305; iTF_00704757; iTF_00698076; iTF_00703743; iTF_00705792; iTF_00895724; iTF_01312045; iTF_00642150; iTF_01317085; iTF_00113936; iTF_00113143; iTF_01316126; iTF_00112318; iTF_01451277; iTF_00301904; iTF_00300973; iTF_00072530; iTF_00150290; iTF_01016373; iTF_00875958; iTF_00875107; iTF_00874258; iTF_00035447; iTF_00284333; iTF_00034513; iTF_00819863; iTF_00851522; iTF_01028066; iTF_00907683; iTF_00374980; iTF_00038501; iTF_00120294; iTF_00449926; iTF_01526822; iTF_00809863; iTF_01092871; iTF_01342024; iTF_01525736; iTF_00124041; iTF_01361385; iTF_01029962; iTF_00036427; iTF_00071211; iTF_00171563; iTF_00037580; iTF_00274252; iTF_00808908; iTF_01192428; iTF_01230316; iTF_01259884; iTF_01264204; iTF_00111406; iTF_00906863; iTF_00122160; iTF_01094704; iTF_01538544; iTF_00121201; iTF_00299954; iTF_00373714; iTF_01093842; iTF_01362898; iTF_00123155; iTF_01439699; iTF_00888020; iTF_00973525; iTF_00072055; iTF_00237271; iTF_00363831; iTF_00622615; iTF_01025783; iTF_00448824; iTF_00757944; iTF_01440792; iTF_00000121; iTF_01030937; iTF_01362297; iTF_00000988; iTF_00905917; iTF_01029022; iTF_00771679; iTF_01027104; iTF_00957768; iTF_00364720; iTF_00021144; iTF_00008706; iTF_00009811; iTF_01463967; iTF_00677346; iTF_01435865; iTF_00011747; iTF_00637283; iTF_01331235; iTF_01491683; iTF_01099684; iTF_00662892; iTF_00119414; iTF_01501892; iTF_00826629; iTF_00832709; iTF_00888997; iTF_00931028; iTF_00932223; iTF_01135559; iTF_00162312; iTF_00280936; iTF_01172136; iTF_00204937; iTF_00441289; iTF_00157006; iTF_01360414; iTF_00446921; iTF_00444913; iTF_00445914; iTF_00985801; iTF_00984834; iTF_00695283; iTF_00457820; iTF_00457821; iTF_00124970; iTF_00326890; iTF_00772682; iTF_00462178; iTF_00148291; iTF_00409093; iTF_00659269; iTF_00410086; iTF_00412327; iTF_00680328; iTF_00660115; iTF_00658164; iTF_00289431; iTF_00411225; iTF_00654041; iTF_01133529; iTF_00655899; iTF_00149182; iTF_01072254; iTF_00871103; iTF_00908618; iTF_01075178; iTF_01564363; iTF_01425772; iTF_00636077; iTF_01245741; iTF_00275054; iTF_00821582; iTF_00825390; iTF_00858353; iTF_01403249; iTF_00161362; iTF_00909554; iTF_01209010; iTF_01207916; iTF_00404499; iTF_00404498; iTF_00823731; iTF_00869427; iTF_01221299; iTF_01424851; iTF_00042435; iTF_00039597; iTF_00041583; iTF_00040598; iTF_00043287; iTF_00147104; iTF_01338292; iTF_01339762; iTF_00818165; iTF_00055207; iTF_00708982; iTF_00341143; iTF_01197527; iTF_00822692; iTF_01332349; iTF_01436823; iTF_01416577; iTF_01251555; iTF_00006889; iTF_01415627; iTF_00761431; iTF_01083104; iTF_00282073; iTF_00647803; iTF_01151867; iTF_01010173; iTF_00063385; iTF_01387421; iTF_01385513; iTF_01388273; iTF_00706750; iTF_00850398; iTF_01134590; iTF_01487518; iTF_01115520; iTF_01495590; iTF_01494126; iTF_01496369; iTF_00922706; iTF_01494868; iTF_01166400; iTF_00146200; iTF_00278919; iTF_01531768; iTF_01534599; iTF_01063553; iTF_00711618; iTF_01533739; iTF_00928463; iTF_00685235; iTF_01061685; iTF_01064438; iTF_01062558; iTF_01532832; iTF_00250266; iTF_00321402; iTF_00887226; iTF_00075265; iTF_00383425; iTF_00967853; iTF_01377275; iTF_00017148; iTF_00017983; iTF_00431937; iTF_00432940; iTF_00947706; iTF_00994177; iTF_00342018; iTF_00621826; iTF_00076259; iTF_00896579; iTF_01020995; iTF_01034339; iTF_00959975; iTF_00958512; iTF_00461362; iTF_00959219; iTF_00842455; iTF_01033527; iTF_01082243; iTF_01359523; iTF_00012740; iTF_01171269; iTF_00007814; iTF_01170374; iTF_01205510; iTF_01202279; iTF_01204679; iTF_01203850; iTF_01203052; iTF_00878675; iTF_00430424; iTF_01206361; iTF_01503654; iTF_01547334; iTF_00649831; iTF_00648915; iTF_00801607; iTF_00954216; iTF_01358695; iTF_00859266; iTF_00044264; iTF_00273416; iTF_00951597; iTF_00290472; iTF_00787427; iTF_00780072; iTF_00212232; iTF_00247848; iTF_00776584; iTF_00213225; iTF_00774318; iTF_00780846; iTF_01181711; iTF_00782448; iTF_00159635; iTF_00775860; iTF_00777812; iTF_00779325; iTF_00722846; iTF_00775071; iTF_00781631; iTF_00784200; iTF_01285350; iTF_00785821; iTF_00783231; iTF_00390185; iTF_00827785; iTF_01017545; iTF_00194986; iTF_00408202; iTF_00960741; iTF_00751832; iTF_01529002; iTF_00197931; iTF_00205867; iTF_00924395; iTF_01193419; iTF_00074284; iTF_00376908; iTF_00818956; iTF_01091500; iTF_01179308; iTF_01180131; iTF_01182476; iTF_01220460; iTF_00720013; iTF_00794125; iTF_00953325; iTF_01084941; iTF_01084054; iTF_01282029; iTF_01429741; iTF_00428807; iTF_00155118; iTF_00325175; iTF_00156060; iTF_00246990; iTF_00621030; iTF_00785006; iTF_00077295; iTF_00651535; iTF_01081391; iTF_01116975; iTF_01119084; iTF_01118061; iTF_01302095; iTF_01438703; iTF_01437773; iTF_00176912; iTF_00206801; iTF_00666313; iTF_01018385; iTF_00006098; iTF_00651538; iTF_00651536; iTF_00673299; iTF_01402547; iTF_00142900; iTF_00656948; iTF_00345622; iTF_00358326; iTF_00357228; iTF_00640086; iTF_01071446; iTF_01173078; iTF_01073410; iTF_00942615; iTF_01151031; iTF_01335735; iTF_01463063; iTF_00662040; iTF_00856408; iTF_00114745; iTF_00667161; iTF_00710841; iTF_01279993; iTF_01281113; iTF_01428857; iTF_01502777; iTF_00287866; iTF_00025083; iTF_01152850; iTF_00026651; iTF_00027567; iTF_00033627; iTF_00032712; iTF_00353884; iTF_00352845; iTF_00355933; iTF_00354894; iTF_00661085; iTF_00926397; iTF_00913417; iTF_00427902; iTF_00737278; iTF_00632567; iTF_00638457; iTF_00686143; iTF_00971039; iTF_00970213; iTF_01279071; iTF_01401087; iTF_00840128; iTF_00185115; iTF_00185944; iTF_01489947; iTF_00770911; iTF_00681469; iTF_00683131; iTF_00235679; iTF_00236455; iTF_00715615; iTF_00723775; iTF_00317920; iTF_00467264; iTF_00467999; iTF_00635200; iTF_00634121;
90% Identity: iTF_00791004;
80% Identity: -