Basic Information

Insect: Helleia helle
Gene Symbol: lrrfip2
Assembly: GCA_963853865.1
Location: OY971424.1:2046654-2076307[-]

Transcription Factor Domain

TF Family: LRRFIP
Domain: LRRFIP domain
PFAM: PF09738
TF Group: Unclassified Structure
Description: LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 1.4e-75 4.6e-71 240.5 21.9 1 269 190 463 190 481 0.89

2 2 1 3.3e+04 -7.4 14.8 1 44 482 525 482 551 0.68

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	1.4e-75	4.6e-71	240.5	21.9	1	269	190	463	190	481	0.89
2	2	1	3.3e+04	-7.4	14.8	1	44	482	525	482	551	0.68

Sequence Information

Coding Sequence: ATGGTGCGGCTTGGACTGGCGATGGTGGTGGGGGTGGCGCCGGCGATCGTGTCCTGGTGGAGAGGCCAGGCCACGCCGCCGCTCATACAGAGCCCCTGTCTGGAGAAGCCCAAGTTTTGGCCCCAACGGTCGCCGTCGATATCGGATTGTTTGGAGAGCAGTGATGAAGATTCTGCTCGTTCTGTCGTGTGCCACGTGCGGCCGAAACCAAATTCTATAGGTGATGCACAATTGGTGACGACTGACGAGATGGGCAATCGTTCGGAGCTCGCCACACCCGACAACAGCGACGAAGAGAGCGGGGACGCCTTCACCGATGGGGACTTTGGTGATTCTGATGACCAGACGATAATCGAGCGCAGCCCTGAACCTAAATCATCAATACCAGTCAATGAAACTATCAACGGATTCGTGGAAGCCGTCGAAGAGGTACAACTTGTGAATGGCCACTCTTCTGAGAAACTCAATGACGAATCATCTGCGAGGAACGAGGATGTTGACGGACGCAGGGACTCTCACGGCTCCACCAGCTCGATAGTCGGAATACTCGGGGATCAACAGAATCACGCTGAGCAGAGGCTCGCGGCGAGGAGGGCGGCGCGGGCGGAGGCGCGCGAGATACGCATGCGAGAGCTGGAGCGGCAGCAGCGGGAACAAGAGGACCATGCAGACAAGGCCTACGACATGTATGCAGAGACAGTGGGAAGACGCGCCGGCGGTCGGCTAGCAGCTCTAAGCCCCGCCGCCCTGCACTCGCCGCGCCGCAGCTCGGAGGACTCCGACGATGTGCTCAGTGTAAAGGATCTTAGGCACGAACTGAAGGAAGTAGAGGAGAAGTTCCGGAAGGCGATGATCCTGAACGCGCAGTTGGACAATGACAAGGCGGCGCTTGGCTACCAGCTCGAGCTGCTCAAGGACCGGATAGAGGAACTGCAGGAGGAGTTTGCACAGTTACAGAGGGAGCACCGGGAGAAATGCTCTAGTCACGAGCGTCTGAAGCGCGAGCACGCGACGCTCGAGCGGGAGGTGACGCTGGCGCGGGACGCCGTGCGGGCGCGGGACTCCGCCGCCGCCGCTGCGGGCTTCGCCTTCGTAGACGCCGCCTCGGTGGGCGGGGGTGAGGGAGAGGGGCAAGGGGACATGATCGCGGGGGCGGCGGGCGAAGCACACGGCAGCGTGCCGCCGCTGGCGCTCGTTTCGCATCAGTCCGAGCGGTTGCTCAACGACGCGGGGGAGGGGTCGCTAGATGTACGGTTGCAAAACCTGGTGAGCTCGAAGCAGGCGCTGGAGGGGGAGGTGCGCAAGTTGAAGCTGCAGCTGAACGACGAGCGCGCCGCGCGGCAAAATGGCGTCGCCTCACACCACGACCGCGACCACGAGAGCGAGCTGGAGAGCCTGCGCAAGGCGGTGGCGGAGGCGAAAGGGCGCGCGGCGCGGGCGGAGGCAGAGGCGGCGCTGCAGGCGGCGGCGGTGGCGCGGCTCGAGGCGCAGGTGGGACGCCTGCGCGCGCGACACGACCAGCAGGACGAGCACGAGGAGTTGCTTAAGCAGGAGCGCCGTCGTCTGCAGAGGGAGGCGAGAGAGGCCCTCAACAGAGTGGAAGAACTGGAGACAGAGAATAGCCACCTGACAAAGCGGTTGGACAAGTTGAAGAATGCCAAGTCAGCGCTGCTCAAAGATCTGTGA
Protein Sequence: MVRLGLAMVVGVAPAIVSWWRGQATPPLIQSPCLEKPKFWPQRSPSISDCLESSDEDSARSVVCHVRPKPNSIGDAQLVTTDEMGNRSELATPDNSDEESGDAFTDGDFGDSDDQTIIERSPEPKSSIPVNETINGFVEAVEEVQLVNGHSSEKLNDESSARNEDVDGRRDSHGSTSSIVGILGDQQNHAEQRLAARRAARAEAREIRMRELERQQREQEDHADKAYDMYAETVGRRAGGRLAALSPAALHSPRRSSEDSDDVLSVKDLRHELKEVEEKFRKAMILNAQLDNDKAALGYQLELLKDRIEELQEEFAQLQREHREKCSSHERLKREHATLEREVTLARDAVRARDSAAAAAGFAFVDAASVGGGEGEGQGDMIAGAAGEAHGSVPPLALVSHQSERLLNDAGEGSLDVRLQNLVSSKQALEGEVRKLKLQLNDERAARQNGVASHHDRDHESELESLRKAVAEAKGRAARAEAEAALQAAAVARLEAQVGRLRARHDQQDEHEELLKQERRRLQREAREALNRVEELETENSHLTKRLDKLKNAKSALLKDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00687891;
90% Identity: iTF_00925734;
80% Identity: -