Hsub017774.1
Basic Information
- Insect
- Harpagoxenus sublaevis
- Gene Symbol
- -
- Assembly
- GCA_030770355.1
- Location
- JASTWR010000154.1:102613-110273[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 6e-13 4.1e-09 37.3 0.3 10 69 280 337 275 342 0.85
Sequence Information
- Coding Sequence
- ATGGACGTCGCGAACGTGAATGGCGGGAACGCCGCGGTACCGCGCGACGATTCTAACCTCGAaagtggcggcggcggcggtggtgctAGTGGTGATACGGCGGTCGTATCAATGGTGGAGACGCAGAACTCGAGCGACAAGGCACAACTGACGGCAGGCGGTAATGCGGACGCGCAGGAGGTTAACGGCGAGCTGAGAGGCACGCCCAGGAAACACGGCACGTCGCTCCCCCGCAGGAGGCTTAGACAGTTCAAGGCCAACTCCATGGGCACGATGGAGATCGACACGGCGGATGCGCCTGGGACGAGGGGACGCAAGCGCAAGCTCTCAGAGTACGAAGACGCCAGCTCCGAGGACTCCGAGGAGTTCAACGGCTTCGACTCCCAAGGACTCGAACTCCAACCAGGCAGTCACGTTCTGAGCAAACTCATTGCTGAAGCAGAAATAGCAGAAGCACAAGTCACAAAACGCGTGAAATATTCAACGAGGTCTTTCGACGCTAGAGAAAGAATAGATGACAATCAAGATTTTGATCACATGAGAACGTACGTTTACGAAACGGATAGTTTCGAGCATTTGGATAtgacaaatattaaaaaagaaaaagagtcCGATAAATCGGAAACAGATTCTATTGATATACCAAATAGCATAGATTCCGAAGTCGAGCCAAACAAAATTGATATAACTTCCATTAGATCGGCAAATTCATCGTCGGCGGCGAGTAGTCCCTCGGCAACATCGCAAAAATCAAAAGGTAGCCTCATTTCTGGCGGCGCAAGTCCAGGGGGGAAGCATAAAACTCCTGTTGATATGTCAAACCCTTTATACAAAGAGCCATTTAAATATGGGTGGAAGCGAGAATTAGTATTTAGAGCTAGTCATGACTCTTCCTTCAAAAAAATGGCTGACATATATTACTACACACCAAAGGGGAAAAAGGTCAGGAGTTTTAGAGAAGTTGCAGAATCTCTTAATTCAAAGGAGCTGAGTATGGATAATTTCACATTCTTTAAAGAACCTATTGGGCTTAATGATCCAGAAAAGGAGATTATTCGAGATGCTAAAAGATCACGAGGTGGATCTATGGGTGGATCttcaataaagaaatataatagaaaatctGTAGCAATAAAAAAGACAGTACAGGAACCTGTAACCAAAAAATCAGAACCTGCAACGAGAAAATCGTTAAATGAACCTAGTACTTCAAAAAAGCAGCCGGTACAAGAACCTCCTACTGCTGCACCTGCATCTGCACCTGCAGAAGCTTCAAAATTTGTCCCTGCGTCTGTGTCAGCACCTACAAAGGCAGCTAAATCGGCAAAAGCATCTCCAGCATATAAAAGAACAACAACAAAGAAAACTCCTCAAATAACAGAAATAAAATCACCAGCCGAAGAAAACGAAATGCTCCCACCTCAGCGGAGTACAGCAAATACGAGAAGAGGTCAACCACCCGTTGAGAAGGTTATACCAGTCAAAACCAAAAGATTGTTAACGCGTCCCAAAGTTCAAGAACCATGCAGCATAAGATGTTCGACAAGTATGGGATTAATACCAAGTTTACAATGTCGAGTTTGTCTCTGTTTATATCATCCTGAATGTGTCGACGGCATGGAATTTACAGGCAATGATGAATATGTTTGCAAGAATTGTCAACCGGATACTAAAGAATCTCACATGCCAAACAATCCGTCTTTAACACCACCTCCGTTGATTCCAATTAGTATGTTAGGTGCACAAAATGCGAAATCAAGACATCAGACTAATTCATCTCCACCGAAATTGCAAAGAATTCCAAAGTCCGAGGGTGCGGAAGCGCAAATAAGAAATTCTTCCAAAACTACCAAAATACCATCTTCAGTATCAAATTTGCCCTCAACTGTGGATAAAAAGGAAAGTACTTGGTTTCCTCAGACGGAGAATGAATTTCTACAAAGTCACGATGGCACTATGCCGAAACCGGCTCAAAATATCGCTGTAATGGGCGGCAAAAGATACATTGTAGTACCAAAAAATAACGCAATGGCAGTTCAACCGGCTATAACAGTAAAACCAGATAAAATTGGCGATAAACCGCCAATGCTTCAAGACGGTTTACTTACCGACATTTCGAATACTACAGATAATTCTGTAGCAAACTTATGTGCACCTCCACCTTTAAATACTGATTTACCTGAAAAAATAGATGTTACACctgataaagaaattttaaaagatacgATTCATCAGACGGATTTTACATCTATTACTACTGAAATGGCTGAAACATTTATGTATGATAATAAAGATAAGGATAGCAACAATACTACTAAAGGAGATCCTGTTGAAGATAATCCTATTGAAAATACATCAGAAAACGAATCTTTTACTGCCAATATAGATTATGTCtcagaaagagaaaaaacagaTACAAGTTGTAAGTCACCTGAAAGTAAATCTGCATGTATATCAGTACATTCGGCAAATATTACAAATACTCTTGAAGCAAGTGTAGAAACTGAAGCAATTAAAATAGATCAGCAACAATCATTACCAAGTAAAGTGGGTAcagtaaaaaaaatgaaaaatagcaaGAGGAAGCAAAATCAACAGGAATTAGAGCAACAGCAAAATTTCATGAACTCAGTTTGCGCCGGTTATCATGCCCTGCTGCGTATTTTCCAATATCTTAAAGTCCAAGAATTATTGCGAGCCGCGCGAGTTTGTAAAATGTGGCGTGATCTCGCTGCACATCCATCTCTATGGAAGACTGTACGAATGAAGAACAGTCAAGTAACTGACTGGGATGGTTTGGCGGATACGTTGCAAAGACGTGGCACGCAGCATCTAGATCTCAGGAAAATGCTGGTTGCTGGCGAGTCCGACAACATCTGGAGGAAATTTCTGACTGTCATACCACGAGTGACCAGTCTCGTAAAGCTTGAACTATGCAGATGTCCCGTTATGGTCGTGGAAGAAGTTATTAAGAGTTGCCCACAGTTGGAGGTATTCAGTGCAATGTCGATCAAGTGCGACTCTCTCACATTAGAGTCGATCGGGAACTTGAGTCGATGTCAAGAACTCAGACTCAAAGCAATAACAGGAATGTCATTACAACAAGATCTTACGCCTTTACAGGACTTAAAGCACTTGACACAGTTGAGTTTAACATCGGTTAAAGAACTTGGGAAGAAAAAAATTGACGTTATACAAGCGTTGACAAACTTGGAGACGTTAGAATTGGGCGAATGCTCCGATTTTCCTGACAAGTTTGGAACTACCGTTTTAATCAACTTAAATAAATTGGAACGTCTTAGACTTGAAAAAGGTCAAGGATCTTGTTGTACATTTGATATCCTCGAAGGTGTATCAAAGTTGGAGAACTTGAGTCAGATGGAATTGGTTAATTTTGATGTGAAGAATGGCTTTGACAAATGTCTTGCTAATTGCAAAAACATCAAAAGGTTATTGATCATACCGACTTATATATCACAATCGGCGACATCCAATAACATGGTGCTCGGAGGTGTCACAGAATTGTCAGACAATTTGACGCATTTCATATGGGGCGTTACGCTCGAGTTACTCAGGGTCACAGAACTGTTCGTTGATCAGTGCAACCTCATGAGTAAACAGGTTACTGGGGATTCTATACCAGTTTTAAAACCTGTTCCCTGCTTAAGATTAATCGAGGATGTTGAGGATGAGAACGAGAACCAAAAAGgTGACGACAAGCAACAGCCTCATCTAACAAGCCCGCAAGTCGACATTTTACCGTTGCCACAATTGCAAAAGCTTCTTTTAACCGCGTTGCCCAAGACACGAGTTAAGATCTTAAAAATCCCTTTTCACGCCACGTGGCGGCAGAGCATTTCCGATACCACTACGCAGTAG
- Protein Sequence
- MDVANVNGGNAAVPRDDSNLESGGGGGGASGDTAVVSMVETQNSSDKAQLTAGGNADAQEVNGELRGTPRKHGTSLPRRRLRQFKANSMGTMEIDTADAPGTRGRKRKLSEYEDASSEDSEEFNGFDSQGLELQPGSHVLSKLIAEAEIAEAQVTKRVKYSTRSFDARERIDDNQDFDHMRTYVYETDSFEHLDMTNIKKEKESDKSETDSIDIPNSIDSEVEPNKIDITSIRSANSSSAASSPSATSQKSKGSLISGGASPGGKHKTPVDMSNPLYKEPFKYGWKRELVFRASHDSSFKKMADIYYYTPKGKKVRSFREVAESLNSKELSMDNFTFFKEPIGLNDPEKEIIRDAKRSRGGSMGGSSIKKYNRKSVAIKKTVQEPVTKKSEPATRKSLNEPSTSKKQPVQEPPTAAPASAPAEASKFVPASVSAPTKAAKSAKASPAYKRTTTKKTPQITEIKSPAEENEMLPPQRSTANTRRGQPPVEKVIPVKTKRLLTRPKVQEPCSIRCSTSMGLIPSLQCRVCLCLYHPECVDGMEFTGNDEYVCKNCQPDTKESHMPNNPSLTPPPLIPISMLGAQNAKSRHQTNSSPPKLQRIPKSEGAEAQIRNSSKTTKIPSSVSNLPSTVDKKESTWFPQTENEFLQSHDGTMPKPAQNIAVMGGKRYIVVPKNNAMAVQPAITVKPDKIGDKPPMLQDGLLTDISNTTDNSVANLCAPPPLNTDLPEKIDVTPDKEILKDTIHQTDFTSITTEMAETFMYDNKDKDSNNTTKGDPVEDNPIENTSENESFTANIDYVSEREKTDTSCKSPESKSACISVHSANITNTLEASVETEAIKIDQQQSLPSKVGTVKKMKNSKRKQNQQELEQQQNFMNSVCAGYHALLRIFQYLKVQELLRAARVCKMWRDLAAHPSLWKTVRMKNSQVTDWDGLADTLQRRGTQHLDLRKMLVAGESDNIWRKFLTVIPRVTSLVKLELCRCPVMVVEEVIKSCPQLEVFSAMSIKCDSLTLESIGNLSRCQELRLKAITGMSLQQDLTPLQDLKHLTQLSLTSVKELGKKKIDVIQALTNLETLELGECSDFPDKFGTTVLINLNKLERLRLEKGQGSCCTFDILEGVSKLENLSQMELVNFDVKNGFDKCLANCKNIKRLLIIPTYISQSATSNNMVLGGVTELSDNLTHFIWGVTLELLRVTELFVDQCNLMSKQVTGDSIPVLKPVPCLRLIEDVEDENENQKGDDKQQPHLTSPQVDILPLPQLQKLLLTALPKTRVKILKIPFHATWRQSISDTTTQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01523359;
- 90% Identity
- iTF_00885109; iTF_01407284; iTF_01405697; iTF_01408218; iTF_01409115;
- 80% Identity
- -