Gpyl020081.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Glyphodes pyloalis
Gene Symbol
Lztr1
Assembly
GCA_037074685.1
Location
JAYKKO010000021.1:2322134-2339005[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 1.2e-16 5.6e-14 53.2 0.0 4 109 364 500 361 501 0.86
2 3 2.5e-17 1.2e-14 55.4 0.0 8 97 598 687 595 702 0.86
3 3 2.1 9.8e+02 0.9 0.0 77 105 701 729 690 733 0.79

Sequence Information

Coding Sequence
ATGCAAAATATAGCGAAAATGATAACAGAACAACTTAGAAATCCAAATGAGCTGGATATTAGTTTACGAATGGAGTTCGGCCCTTTCGAAACAGTGCACAAGTGGAAACGCATGTCCGAGTGTTACGAGTTCGTAGGAGCCAGACGGAGCAAACATACTGCAGTGGCATACAAGGACGCAATCTATGTATTTGGTGGAGATAATGGGAAATCTATGCTTAATGATCTCATACGATTTGACATCAGGGAAAAGTCCTGGACAAAAACTGGGTGCATGGGGGTGCCTCCAGCCCCTCGCTATCACCACTCTGCTGTAGTGCATAGATCATCCATGTTTGTGTTTGGTGGTTACACTGGTGACATTCTGGCTAACTCGAATCTGACCAACAAGAATGATCTGTTTGAGTACAAGTTCCAGAACGCACAGTGGGTGCAATGGAAATTCACTGGACAAGAACCAGTGCCAAGATCCGCTCACGGGGCGGCAGTCTATGATGACAAACTGTGGATATTCGCCGGCTACGACGGCAACGCTCGCCTGAACGATATGTGGACTATCAACTTGATGGGTGAGAACCACCAATGGGAGAAGGTGGAGCAGAAGGGCCAGTGTCCACCGACGTGCTGCAACTTCCCGGTGGCTGTGGCGCGAGGGAAGATGTTCGTCTTCAGCGGGCAGAGCGGTGCTAAGATCACCAATGCGCTGTTCCAGTTTGACTTCGAGACTCATACATGGAGCCGCGTGTGCACGGAGCACCTGCTGCGCTGCGCAGGCCCGGCGCCGGCGCGCCGCTACGGACACGCCATGCTGGCGCACGGACGACACCTCTACGTGTTCGGCGGAGCCGCCGACAACACGCTGCCCAGCGACCTGCACTGCTACGAGCTCGACACGCAGATGTGGTCAGTGGTCCAGCCAGCTCCTGACTCGCAAATACCGTCTGGCCGTCTGTTCCATGCGGGCGCGGTGGTGGGTGATGCGATGTATATCTTCGGAGGAACAGTGGACAACAACGTGCGCAGCGGGGAACTCTTCAGATTCCAGTTATCTAACTACCCGCGCTGCACCCTACACGATGACTTCGGCCGGATACTGAAGTCGCAACAGTTCTGCGACATAACATTACTCGTTGGCCCGGAGAAGGTTGCCGTCAAAGCTCACCAGGCCATGCTCGCGGCCAGGTCTCAGTACCTTAGGGCCAAGATAAAGGAGGCACGTGAAGAGTTGTTAAAACGCATAGCATCGGGCGAGCAGGCCGCTTCGGAATTTTACTCTTACAAAGCAGAGCCAGCTCTCACTGTGCACCTACCAGAAGCGACGCCCGAAGCCTTCAACATGGTTCTTAATTACATTTACACAGACAGGATCGATCCTACTGAGAAAGATGAGGACCCAGCATCACCTGCAACCATCCTATTAGTGATGGAGGTGCTACGTCTCGCGCTGCGGCTCAGCATTCCTCGGCTCCGTGGTCTGTGTGCGCGGTTCCTTCGCGccaacttgtgttacagcaacgTGCTGCCTGCGTTGCATGCCGCTCATCACGCCAACCTGAGCTGCATCAAAGAGTATTGCTTGAGATTCGTAGTGAAAGATTACAACTTCACGCCGATCGTGATGTCGGCTGAGTTCGAGGAGATGGAGCAGAGTCTGATGGTGGAGGTTATACGCCGCCGGCAGCAGCCGCCGTGCAAGCAGCCCGCCACCGCGCACCACGACTGCGATGAAGAGATCCTTGGAACAACTCTAGAGCAAGACATGAGTGTGTTCGCGAGCGGCGGCGCAGGCGGCGGCGAGCTGAGCGACGTGCGCCTGCGCGTCGGCGCCGCCACCAGACCCGCGCACCGCTCCGTGCtggccgcccgcgccgcctacTTCGAGGCCATGTTCCGCTCCTTCTCGCCGCAGGACAACATCGTCAACATTCAAATCTGCGACACAGTACCTTCGGAGGAGGCGTTCGATTCTCTATTGAGGTACATCTACTACGGCGATACCAACATGCCGACAGAAGATTCTCTTTACCTATTCCAAGCACCCATTTATTATGGGTTCACCAACAACCGTCTCCAAGTATTCTGCAAGCACAATCTACAGAGTAACGTGTCTCCAGAGAACGTACTGGCTATCCTTCAGGCCGCTGACCGCATGCGCGCCGCTGATATCAAGGAGTATGCTCTCAAGATGATCGTTCATCAGTTCGGCCTGGTCGCCCGCCAAGACGCGATCAAGAACTTAGCTCAGCCGCTCTTAGTGGACATAATATGGGCGGTGGCGGAGTCCCCGCAGTTCGACACGCCGCTGCAGAGGTCGCTGCCGTCCTCCGCCTCGCAGGACACGCTCGCCGACGACCCCGACTACCGCCACAGGCAACCCAAGTAG
Protein Sequence
MQNIAKMITEQLRNPNELDISLRMEFGPFETVHKWKRMSECYEFVGARRSKHTAVAYKDAIYVFGGDNGKSMLNDLIRFDIREKSWTKTGCMGVPPAPRYHHSAVVHRSSMFVFGGYTGDILANSNLTNKNDLFEYKFQNAQWVQWKFTGQEPVPRSAHGAAVYDDKLWIFAGYDGNARLNDMWTINLMGENHQWEKVEQKGQCPPTCCNFPVAVARGKMFVFSGQSGAKITNALFQFDFETHTWSRVCTEHLLRCAGPAPARRYGHAMLAHGRHLYVFGGAADNTLPSDLHCYELDTQMWSVVQPAPDSQIPSGRLFHAGAVVGDAMYIFGGTVDNNVRSGELFRFQLSNYPRCTLHDDFGRILKSQQFCDITLLVGPEKVAVKAHQAMLAARSQYLRAKIKEAREELLKRIASGEQAASEFYSYKAEPALTVHLPEATPEAFNMVLNYIYTDRIDPTEKDEDPASPATILLVMEVLRLALRLSIPRLRGLCARFLRANLCYSNVLPALHAAHHANLSCIKEYCLRFVVKDYNFTPIVMSAEFEEMEQSLMVEVIRRRQQPPCKQPATAHHDCDEEILGTTLEQDMSVFASGGAGGGELSDVRLRVGAATRPAHRSVLAARAAYFEAMFRSFSPQDNIVNIQICDTVPSEEAFDSLLRYIYYGDTNMPTEDSLYLFQAPIYYGFTNNRLQVFCKHNLQSNVSPENVLAILQAADRMRAADIKEYALKMIVHQFGLVARQDAIKNLAQPLLVDIIWAVAESPQFDTPLQRSLPSSASQDTLADDPDYRHRQPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00876289; iTF_00008130; iTF_00006375; iTF_01081704; iTF_00257058; iTF_00256051; iTF_00642467; iTF_00761795; iTF_01251947; iTF_01083468; iTF_01386828; iTF_01385909; iTF_01387707; iTF_01388604; iTF_01416953; iTF_00007230; iTF_01017827; iTF_01018676; iTF_00771172; iTF_01202564; iTF_00407685; iTF_00406850; iTF_00430757; iTF_00878937; iTF_00161670; iTF_01203334; iTF_01204997; iTF_01206668; iTF_01205800; iTF_00774574; iTF_00780336; iTF_00781114; iTF_00674391; iTF_00806831; iTF_00205287; iTF_01021405; iTF_00942934; iTF_00468263; iTF_00621319; iTF_00076674; iTF_00075651; iTF_00648228; iTF_00074667; iTF_01124701; iTF_00782732; iTF_00776100; iTF_00775351; iTF_00820201; iTF_00819284; iTF_00050058; iTF_00833187; iTF_00171956; iTF_00433258; iTF_00948002; iTF_00345928; iTF_00457321; iTF_00458154; iTF_00276558; iTF_00828051; iTF_00432350; iTF_00681738; iTF_00683463; iTF_00682543; iTF_00724042; iTF_00836682; iTF_00985258; iTF_01042762; iTF_01544046; iTF_01544982; iTF_01543063; iTF_01546749; iTF_01220746; iTF_01508170; iTF_01506460; iTF_01507324; iTF_00208011; iTF_00208977; iTF_01463403; iTF_00213644; iTF_00723244; iTF_00247310; iTF_00159951; iTF_00212655; iTF_00248212; iTF_00622092; iTF_00844492; iTF_00986348; iTF_01151308; iTF_00802017; iTF_01452460; iTF_00355310; iTF_00994446; iTF_01331822; iTF_00736710; iTF_01334001; iTF_01073711; iTF_01503087; iTF_00010256; iTF_01464271; iTF_00009173; iTF_00144752; iTF_00358737; iTF_01562094; iTF_00357745; iTF_00408561; iTF_00365037; iTF_01071729; iTF_00021426; iTF_01079154; iTF_01080822; iTF_01079997; iTF_01090898; iTF_01564788; iTF_01155477; iTF_01154209; iTF_00855955; iTF_01561212; iTF_01246037; iTF_01453366; iTF_01041923; iTF_01451613; iTF_00000439; iTF_00012119; iTF_01302501; iTF_00013185; iTF_00072934; iTF_00146540; iTF_00640524; iTF_00720460; iTF_01016855; iTF_01401399; iTF_00026968; iTF_00027876; iTF_00319032; iTF_00961048; iTF_01193688; iTF_01336984; iTF_01430040; iTF_01545848; iTF_00236730; iTF_00235953; iTF_00290811; iTF_01487816; iTF_00824859; iTF_00843640; iTF_00834747; iTF_00837678; iTF_00035838; iTF_00284659; iTF_00428254; iTF_00429144; iTF_00115040; iTF_01337824; iTF_01494401; iTF_01176260; iTF_00197451; iTF_01115790; iTF_01402798; iTF_01495123; iTF_01495859; iTF_01130112; iTF_00922958; iTF_01173392; iTF_00958033; iTF_00195251; iTF_00840373; iTF_00204439; iTF_01547961; iTF_00249790; iTF_00180578;
90% Identity
iTF_01155477;
80% Identity
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