Ebru027349.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eurytoma brunniventris
Gene Symbol
Rfx2
Assembly
GCA_900475205.1
Location
UXGB01001805.1:15185-21357[-]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 3.7e-37 5.4e-33 114.1 0.0 3 78 273 348 271 349 0.97
2 2 1.6 2.4e+04 -3.3 0.0 39 62 497 520 492 523 0.63

Sequence Information

Coding Sequence
ATGACTACGACAGGAGCCCAGTACGCTCTCGCAGCATCCACCGGGGCTGGCAATGGCGGGGGCAACTCCATAGTGGGGGATGAAAAGCCAAGCGTCGTCGTTGTTACTACTTCTAATTCCAATGGAAATGGAAGCGTTGCCCAGTCACAGTCAGGACGGGGTCAGCAGTTAATCACTGTAGTTACAAGTGATCCTTCTAGCCCTAATAGTCTGCAACCTATTCAGTTGCTAGTTCAAGACTCACTGGATGCAACTGCAGATTCGTCAAATGGTTCATCTGGTACACAAGCACATGTAACAGCACAAGTAGTTGTAAACACAACACATTCTGGTCAGCACACTCTAGTGGACTCAGACGCTGCATCAACTTCAGCCGGTACAATTGTCAGTGGATCACCTCACTACATTACAGTTAcagGCACCAGTGATTCACCATCATACGCATCCCTCACAACGGCTGTAGttccTGGTGACGCTGACGCCGTGGGGTCGGAATCAGTTACGCATCCCACCTACGTCCAGTATGTCGAAGGCGATGGATCCACGTATATACCGACAAATGGACAGATgaCATATCCTGTATACGCGGTTGGCGAGGCGGGAACGATGTACACTCCCGCCTCCAACCAGTATTACACTTCAACTACCACACCCGTGACTTACGCTcagGTCACGGGTTCGAGCACAACAACGGGTCAGCTTTTGGCACAGGGTAATGGAACGTACCTGATCCAGCAGAGCGTCGTGGAGAGCGATCCGACGACGCACGCCCTGTTATcagccgccgcagccgcccgCGCCAGTCCCCAGACCGAGAACGCCGTGCAATGGCTGTTGGAAAATTACGAGACAGCTGACGGAGTGTCGCTTCCAAGATCGACGTTGTATAACCATTACCTGCGCCACTGTTCCGATAGCAAATTAGACCCTGTAAATGCGGCTAGTTTTGGGAAACTCATTAGATCTGTATTTTTGGGCTTACGCACAAGACGTCTTGGAACTCGAGGTAATTCAAAGTACCACTACTACGGCATCCGAGTGAAACCGAGTTCACCGCTGGTGATGCTGAACGAGGACGGCACGTCGCGGCAGCAGACCTCGTCGGCGGCGGTAGCGGCAGCCAACGCGCAGGCGAACAAGCGCGTCAAGTTCGTGAGCCAGAAGCAGTCGGAGGCGGCGTACGAGACGAGCGCGCAGTCGGCCAACAGCGCTAACCTGGCGGCGAACACGGCCTCGCCGCCGCAGTACCACCAGTACCTGGGCGAGGCGAGCTGCGCGATACCCGAGTTCCCGGAGATCGCCGTCGGGCCCTCGCTGCCCGACGACTGCACCCTCGAGGACATCGACACCTTCCGCAGCATCTACCGCGAGCACTGCGAGGCCTTCCTCGACGCCGTCCTCAACTTCGAGTTCGCCACCGTGGAGAGCCTCTGGCGGGAGTTCTGGCGGAGCCAGGACAACAACAACGGCGACGAGTGCGAGGAGGAGAAGTACCTGTCCAAGACTAAGCTCTACCAGATGTGCAAGTGCGTCGAGGTTCAGGAATTCATCCGACGGGTCGACTACACGTTTTATCAGAATCTCGTTGAGGTCCTCATGCCTGACGTACTCAGGCCTATACCGAgtCCTCTGACACAATCCATTAGGAATTTTGCTAAAGGTTTAGAATCTTGGTTAACTTCTGCTATGCACGACTGCCCCGAAGAAATGATGCAAATCAAATTGACAGCAGTATCCGCGTTCGCTCAAACTCTTAGACGGTACACATCATTGAATCACTTAGCTCAAGCAGCCAGAGCAGTGCTTCAAAATAATAGTCAAATTAATCAAATGTTGGCAGATTTAAACCGAGTTGACTTTCATAATGTACAGGAGCAGGCTTCCTGGGTTTGTCAGTGTGATTACTCAGTGGTACAGCGCTTGGAGGCAGATTTCAAAGTGACTCTGCAACAGCAAAACTCGCTTGAACAATGGGCTGTGTGGTTGAAGGGTGTCGTGACCCAAGTTCTCCAGCCTTACGAGGGCAAGCCTACTTTTGCCAAAGCAGCACGACAGTTCCTGCTCAAGTGGTCTTTTTACAGTTCGATGGTCATAAGGGATTTAACCTTGAGAAGTGCCGCTAGTTTTGGATCGTTTCATCTCATCCGTTTACTTTACGACGAATACATGTTTTACTTGATTGAGCATCAAGTAGCACTTTCCACGGGCACCACACCAATAGCCGTCATGGGagataAAACGCAGACTTGTTCAATGATAAATGTTTTTGGATCTAATGgagaTCTATCAAACATATGCCCAACAAAACGCGTGAAACTGAGCTAA
Protein Sequence
MTTTGAQYALAASTGAGNGGGNSIVGDEKPSVVVVTTSNSNGNGSVAQSQSGRGQQLITVVTSDPSSPNSLQPIQLLVQDSLDATADSSNGSSGTQAHVTAQVVVNTTHSGQHTLVDSDAASTSAGTIVSGSPHYITVTGTSDSPSYASLTTAVVPGDADAVGSESVTHPTYVQYVEGDGSTYIPTNGQMTYPVYAVGEAGTMYTPASNQYYTSTTTPVTYAQVTGSSTTTGQLLAQGNGTYLIQQSVVESDPTTHALLSAAAAARASPQTENAVQWLLENYETADGVSLPRSTLYNHYLRHCSDSKLDPVNAASFGKLIRSVFLGLRTRRLGTRGNSKYHYYGIRVKPSSPLVMLNEDGTSRQQTSSAAVAAANAQANKRVKFVSQKQSEAAYETSAQSANSANLAANTASPPQYHQYLGEASCAIPEFPEIAVGPSLPDDCTLEDIDTFRSIYREHCEAFLDAVLNFEFATVESLWREFWRSQDNNNGDECEEEKYLSKTKLYQMCKCVEVQEFIRRVDYTFYQNLVEVLMPDVLRPIPSPLTQSIRNFAKGLESWLTSAMHDCPEEMMQIKLTAVSAFAQTLRRYTSLNHLAQAARAVLQNNSQINQMLADLNRVDFHNVQEQASWVCQCDYSVVQRLEADFKVTLQQQNSLEQWAVWLKGVVTQVLQPYEGKPTFAKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLIEHQVALSTGTTPIAVMGDKTQTCSMINVFGSNGDLSNICPTKRVKLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00254817;
90% Identity
iTF_01523777;
80% Identity
-