Basic Information

Insect: Euphydryas editha
Gene Symbol: Foxd3
Assembly: GCA_036937285.1
Location: JAUPFZ010000016.1:15262986-15263867[+]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 6.1e-41 1.2e-37 129.2 0.0 2 87 89 173 88 174 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	6.1e-41	1.2e-37	129.2	0.0	2	87	89	173	88	174	0.97

Sequence Information

Coding Sequence: ATGGAAGACTGCGACTTGAGTCAGTACCGCGACATGATCATCGAGGGTGACTTACCGCTCGACttgcgcccgccgccgcgcctcTACCTGCCGCACTACCTGCGCGACGACCGCGAGGAGTATCAGGACGAGCCCTATGTCTCCGTAGACGAGGACGCGCCGCCGCCGTCGAGCGATTCCGAGAGATACGATGCGTCGAGTCCGAGCGAATCGAAACCCAGCTCACCGAAAAAACCAAAGCAGAAGTCTTCCTCGCAACTCATCAAGCCGCCCTACTCTTATATTGCACTAATAACGATGGCCATCCTTCAATCGCCGCACAAGAAGCTGACGCTGAGCGGGATCTGTGAGTTTATTATGACAAGATTTCCATATTATCGCGAAAAGTTTCCCGCTTGGCAAAATTCGATTCGCCACAATTTAAGTCTTAACGACTGCTTTATAAAAATTCCCCGTGAGCCCGGTAATCCAGGGAAAGGTAATTACTGGACGCTCGACCCGTTGGCGGAGGATATGTTCGATAACGGAAGTTTTTTGCGCCGTCGGAAGAGGTACAAGCGGCCCGCGCCGTCGTTGCAGCACGCTCACGCGGTGGTAGCGATGCTCGCCAGGGAAGCCTACGCACCTCTTTTGCCTCTACCGTGCTATTTGCCACCGTCGCCGTTGTTGACGctgccgcgcccgccgccggcGGCGCTGCGGCCGGTCGCTCTGCCGCCGCGCGTCGCGGAGACGACGGAGACTAGAGTCAAGAGATCCAGGAACGGTTTCTCAATCGAGTCCATAATCGGATCACAGGAGAGTCAAGTGTCGGAGCCGAGGCGAAGTGCCTTCTCGCCCCTGCACCAGGGCGCCGGCCCGCCGGAGGACTGGGCGAGATGA
Protein Sequence: MEDCDLSQYRDMIIEGDLPLDLRPPPRLYLPHYLRDDREEYQDEPYVSVDEDAPPPSSDSERYDASSPSESKPSSPKKPKQKSSSQLIKPPYSYIALITMAILQSPHKKLTLSGICEFIMTRFPYYREKFPAWQNSIRHNLSLNDCFIKIPREPGNPGKGNYWTLDPLAEDMFDNGSFLRRRKRYKRPAPSLQHAHAVVAMLAREAYAPLLPLPCYLPPSPLLTLPRPPPAALRPVALPPRVAETTETRVKRSRNGFSIESIIGSQESQVSEPRRSAFSPLHQGAGPPEDWAR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00715617; iTF_00790050; iTF_00677347; iTF_00787428; iTF_00323299; iTF_01020996; iTF_01491685; iTF_01501895; iTF_01285353; iTF_00171566; iTF_00636079; iTF_01312047; iTF_00869428; iTF_01221301; iTF_01402549; iTF_01424853; iTF_00000123; iTF_01151869; iTF_00000990; iTF_01360415; iTF_01487519; iTF_01090496; iTF_00642151; iTF_00780073; iTF_00776586; iTF_00775072; iTF_00621032; iTF_00449928; iTF_00889000; iTF_00932225; iTF_00280939; iTF_00282075; iTF_00967855; iTF_00994179; iTF_01154824; iTF_01158522; iTF_01156093; iTF_01153662; iTF_00197932; iTF_01542765; iTF_01545569; iTF_01560938; iTF_01544688; iTF_01546451; iTF_01543709; iTF_00821584; iTF_01027106; iTF_00859268; iTF_00637285; iTF_01028069; iTF_00374982; iTF_00822694; iTF_01526824; iTF_01246633; iTF_01358697; iTF_01525737; iTF_00049707; iTF_00441291; iTF_00726091; iTF_01342027; iTF_00908621; iTF_00924397; iTF_01119086; iTF_01192430; iTF_01230318; iTF_01118063; iTF_01569071; iTF_00794128; iTF_00111409; iTF_01116978; iTF_01538546; iTF_00858355; iTF_00373716; iTF_00823732; iTF_00123157; iTF_00404502; iTF_01439702; iTF_00888023; iTF_00931031; iTF_00341144; iTF_00708984; iTF_00072057; iTF_01025785; iTF_01197529; iTF_00063386; iTF_01435866; iTF_00448827; iTF_00667163; iTF_01440795; iTF_01030940; iTF_01489948; iTF_00425181; iTF_00830973; iTF_01340957; iTF_01010174; iTF_01029023; iTF_00235680; iTF_00706752; iTF_00709997; iTF_01507874; iTF_01078883; iTF_01561827; iTF_01034340; iTF_01506148; iTF_00421157; iTF_00419591; iTF_00687719; iTF_00255624; iTF_00801608; iTF_00959976; iTF_01017547; iTF_00357229; iTF_01193421; iTF_00958513; iTF_00256659; iTF_00959220; iTF_00461365; iTF_01079702; iTF_01033528; iTF_00842457; iTF_00418778; iTF_01080539; iTF_00744414; iTF_01506975; iTF_01091502; iTF_00874260; iTF_00875109; iTF_00875960; iTF_00114747; iTF_01337581; iTF_01451278; iTF_01452146; iTF_01453086; iTF_00180257; iTF_01115521; iTF_01129863; iTF_01495591; iTF_00957770; iTF_01494127; iTF_00249523; iTF_01176019; iTF_01494869; iTF_01496373; iTF_01141462; iTF_00840129; iTF_00112322; iTF_00699906; iTF_00698984; iTF_00700810; iTF_00702698; iTF_00704758; iTF_00783234; iTF_00785009; iTF_00785822; iTF_00806499; iTF_01161123; iTF_01148644; iTF_01145868; iTF_01144365; iTF_01147917; iTF_01140750; iTF_01145110; iTF_00844126; iTF_01171270; iTF_00832711; iTF_00428808; iTF_00818957; iTF_01429743; iTF_00819864; iTF_00427904; iTF_01547337; iTF_00204938; iTF_00290474; iTF_00405738; iTF_00194987; iTF_00985803; iTF_00984837; iTF_00022604; iTF_01142221; iTF_01509389; iTF_00376910; iTF_00696307; iTF_00705793; iTF_00698078; iTF_00909555; iTF_00686145; iTF_01219592; iTF_01529004; iTF_00266993; iTF_01528087; iTF_00119416; iTF_01335737; iTF_00662042; iTF_00638459; iTF_01428859; iTF_00661088; iTF_00737280; iTF_00204180; iTF_01018388; iTF_00113144; iTF_00236457; iTF_00113938; iTF_00818168; iTF_01071448; iTF_00288666; iTF_00925540; iTF_00786575; iTF_00835355; iTF_00836326; iTF_00837275; iTF_00834435; iTF_01317086; iTF_00017151; iTF_00017986; iTF_00791007; iTF_01332351; iTF_00197184; iTF_00703744; iTF_01076192; iTF_01264207; iTF_00275056; iTF_01403251; iTF_00177886; iTF_00649833; iTF_00390187; iTF_01178213; iTF_00055209; iTF_01172137; iTF_00124971; iTF_00648916; iTF_00926400; iTF_00361420; iTF_00810803; iTF_00345623; iTF_00856411; iTF_00934544; iTF_00164130; iTF_00403575; iTF_01217303; iTF_01247895; iTF_00933532; iTF_01500912; iTF_01222290; iTF_00651540; iTF_00185945; iTF_00326892; iTF_00185117; iTF_00468000; iTF_00723777; iTF_00467266; iTF_00161363; iTF_00162313; iTF_01016374; iTF_01336633; iTF_01151034; iTF_00722849; iTF_00212233; iTF_00247850; iTF_00213227; iTF_00246992; iTF_00159637; iTF_00457054; iTF_00457822; iTF_01463969; iTF_00008707; iTF_00635203; iTF_00634124; iTF_00250268; iTF_00896580; iTF_01331236; iTF_01359525; iTF_00409094; iTF_01099686; iTF_01170375; iTF_01182477; iTF_00662894; iTF_00826631; iTF_00166754; iTF_00044267; iTF_01437774; iTF_00352847; iTF_00825392; iTF_01438705; iTF_00142903; iTF_00960743; iTF_00412328; iTF_00778600; iTF_00666314; iTF_00954218; iTF_00032715; iTF_00913419; iTF_01075180; iTF_00736429; iTF_00895725; iTF_00205870; iTF_00206804; iTF_01245742; iTF_01425774; iTF_00682177; iTF_01083105; iTF_01279073; iTF_00770914; iTF_00824514; iTF_00075267; iTF_00462179; iTF_00621827; iTF_01020035; iTF_01416579; iTF_00148292; iTF_00318692; iTF_01073412; iTF_01251556; iTF_01334564; iTF_00011749; iTF_00076261; iTF_01125253; iTF_00659270; iTF_00674118; iTF_01180134; iTF_00012743; iTF_00186951; iTF_00410087; iTF_00447975; iTF_00007816; iTF_01205512; iTF_01503656; iTF_00680329; iTF_01135561; iTF_01202281; iTF_01204681; iTF_00382378; iTF_01204682; iTF_01385514; iTF_00006891; iTF_00772683; iTF_01203852; iTF_01415628; iTF_01564365; iTF_00074286; iTF_01179310; iTF_01203054; iTF_00284335; iTF_00953327; iTF_01220463; iTF_01282031; iTF_00027568; iTF_00155120; iTF_00720016; iTF_00077297; iTF_01081393; iTF_00364722; iTF_01302098; iTF_01388274; iTF_00034515; iTF_00006100; iTF_00673300; iTF_01152852; iTF_00072533; iTF_00878677; iTF_00207670; iTF_00325176; iTF_00358328; iTF_00761432; iTF_01436824; iTF_00640089; iTF_01124409; iTF_01173081; iTF_01463065; iTF_00021146; iTF_00035450; iTF_00146202; iTF_00430426; iTF_00751834; iTF_01133530; iTF_01206363; iTF_01279995; iTF_01281115; iTF_01502779; iTF_00025084; iTF_00026652; iTF_00287868; iTF_00156061; iTF_00647805; iTF_00208638; iTF_00353886; iTF_00683134; iTF_01387422; iTF_00149183; iTF_00681471; iTF_00871104; iTF_01134592; iTF_01386528; iTF_01401088; iTF_00276080; iTF_00317921; iTF_00774320; iTF_00782450; iTF_00775861; iTF_00777814; iTF_00779327; iTF_00781632; iTF_00780848; iTF_01181712; iTF_01367505; iTF_00150292; iTF_00660116; iTF_00658165; iTF_00655900; iTF_01209012; iTF_01207918; iTF_00009813; iTF_00342020; iTF_00656950; iTF_00795510; iTF_01082244; iTF_00144375; iTF_01333537; iTF_00420354; iTF_00289432; iTF_00632569; iTF_00654042; iTF_00411227; iTF_00947707; iTF_00431938; iTF_00277180; iTF_00777245; iTF_00033630; iTF_00355935; iTF_00354895; iTF_01072255; iTF_00971040; iTF_00970214; iTF_00347324; iTF_01377278; iTF_01166402; iTF_00157008; iTF_01339764; iTF_00771681; iTF_01062561; iTF_00147106; iTF_00383427; iTF_01139459; iTF_01532835; iTF_01063556; iTF_00711621; iTF_00851525; iTF_00042438; iTF_00907686; iTF_00038504; iTF_00120296; iTF_01092873; iTF_01534601; iTF_00809866; iTF_01361386; iTF_00124043; iTF_00273419; iTF_00408203; iTF_00446923; iTF_00827787; iTF_00843308; iTF_01029964; iTF_00036429; iTF_00407373; iTF_01533741; iTF_00274254; iTF_00808910; iTF_01077998; iTF_01259886; iTF_00037583; iTF_01084943; iTF_00039600; iTF_00300976; iTF_00951600; iTF_00041585; iTF_00122161; iTF_00906865; iTF_00176914; iTF_00928466; iTF_01094706; iTF_00121203; iTF_00301907; iTF_00444915; iTF_01362899; iTF_00685236; iTF_01093844; iTF_00299957; iTF_00406518; iTF_01338294; iTF_01061687; iTF_01084055; iTF_01443639; iTF_00040600; iTF_00973528; iTF_00237273; iTF_00363833; iTF_00745433; iTF_00942617; iTF_01064441; iTF_00043290; iTF_00172538; iTF_00622618; iTF_00757946; iTF_01531770; iTF_00445916; iTF_00850399; iTF_00905919; iTF_01316127;
90% Identity: iTF_00621032;
80% Identity: -