Epro016307.1
Basic Information
- Insect
- Eudemis profundana
- Gene Symbol
- -
- Assembly
- GCA_947034915.1
- Location
- CAMQQJ010000140.1:1239952-1240487[+]
Transcription Factor Domain
- TF Family
- HMGA
- Domain
- HMGA domain
- PFAM
- AnimalTFDB
- TF Group
- Unclassified Structure
- Description
- This entry represents the HMGA family, whose members contain DNA-binding domains, also known as AT hooks due to their ability to interact with the narrow minor groove of AT-rich DNA sequences. They play an important role in chromatin organisation [1]. The high mobility group (HMG) proteins are the most abundant and ubiquitous nonhistone chromosomal proteins. They bind to DNA and to nucleosomes and are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. They can be grouped into three families: HMGB (HMG 1/2), HMGN (HMG 14/17) and HMGA (HMG I/Y). The characteristic domains are: AT-hook for the HMGA family, the HMG Box for the HMGB family, and the nucleosome-binding domain (NBD) for the members of the HMGN family [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.0067 3e+02 2.5 3.2 11 16 13 18 11 19 0.82 2 4 0.095 4.2e+03 -1.2 2.1 12 15 33 36 32 37 0.93 3 4 4.1e-10 1.8e-05 25.5 2.2 4 21 53 70 51 71 0.87 4 4 0.64 2.8e+04 -3.9 6.9 10 15 84 89 83 90 0.83
Sequence Information
- Coding Sequence
- ATGTCTGATGATGGTTCAACTGCTGTGGAGAAGAAGGGCCGTGGCAGACCTAAATCCAACGGAACACAGGCTGAGGCCAAAGCAGATACAAAGAAAAGAGGTAGACCGCCAGCGGCCACTAAAGCTAAGGAGTCAACAAAGTCCTCTGATGATGAACAAGCGCCGGTAGCGAAACGAGGGCGCGGCAGGCCCAAGGGATCCAAGAAAAAGGCTGCAGCTCCCAAAGCCAAGGGTGGCAGTGGTGAGGGCCGAGGGCGAGGCCGGCCGCGCAAGGACGCGCCGCCTCCTCGGAAGGATGCAGCCTCCACTGAAGAGGAGCAGGATGATGAAGATGAGGATGAAGGCTCCGACCAGTAA
- Protein Sequence
- MSDDGSTAVEKKGRGRPKSNGTQAEAKADTKKRGRPPAATKAKESTKSSDDEQAPVAKRGRGRPKGSKKKAAAPKAKGGSGEGRGRGRPRKDAPPPRKDAASTEEEQDDEDEDEGSDQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00878866;
- 90% Identity
- iTF_00289630;
- 80% Identity
- iTF_00148487;