Ccan016546.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cenopis cana
Gene Symbol
-
Assembly
GCA_951800055.1
Location
OX637479.1:15219412-15221427[+]

Transcription Factor Domain

TF Family
HMGA
Domain
HMGA domain
PFAM
AnimalTFDB
TF Group
Unclassified Structure
Description
This entry represents the HMGA family, whose members contain DNA-binding domains, also known as AT hooks due to their ability to interact with the narrow minor groove of AT-rich DNA sequences. They play an important role in chromatin organisation [1]. The high mobility group (HMG) proteins are the most abundant and ubiquitous nonhistone chromosomal proteins. They bind to DNA and to nucleosomes and are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. They can be grouped into three families: HMGB (HMG 1/2), HMGN (HMG 14/17) and HMGA (HMG I/Y). The characteristic domains are: AT-hook for the HMGA family, the HMG Box for the HMGB family, and the nucleosome-binding domain (NBD) for the members of the HMGN family [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0064 2.6e+02 2.5 3.2 11 16 13 18 11 19 0.82
2 4 0.094 3.8e+03 -1.2 2.1 12 15 33 36 32 37 0.93
3 4 4e-10 1.6e-05 25.5 2.2 4 21 53 70 51 71 0.87
4 4 0.12 5e+03 -1.6 4.6 10 15 83 88 82 89 0.84

Sequence Information

Coding Sequence
atgtcTGATGATGGTTCAACTGTTGTAGAGAAGAAGGGCCGTGGCAGACCTAAAGCCAATGGAACACAAGCTGAGGCCAAAGCAGATACAAAGAAAAGAGGTAGACCGCCAGCGGCTACAAAAGCTAAAGAGTCAACCAAGTCCTCTGATGATGAGCAGGCGCCGGTAGCGAAACGAGGGCGCGGCAGGCCCAAGGGATCTAAGAAAAAGGCAGCTCCCAAAGCCAAgGGTGGCAGTGGCGAGGGCAGAGCGCGAGGTCGGCCGCGCAAGGatgcgccgccgccgcggaaAGACGCCGCCTCCACCGAGGAGGAGCAGGACGACGAGGATGAGGATGAAGGCTCCGACCAGTAA
Protein Sequence
MSDDGSTVVEKKGRGRPKANGTQAEAKADTKKRGRPPAATKAKESTKSSDDEQAPVAKRGRGRPKGSKKKAAPKAKGGSGEGRARGRPRKDAPPPRKDAASTEEEQDDEDEDEGSDQ