Esil009242.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ecliptopera silaceata
Gene Symbol
prg
Assembly
GCA_932527285.1
Location
CAKOBM010000045.1:2109933-2111763[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.36 21 6.1 0.7 2 19 179 196 178 201 0.82
2 10 0.0013 0.079 13.7 0.5 1 23 207 230 207 230 0.96
3 10 1.2e-05 0.00073 20.1 3.5 1 23 236 258 236 258 0.96
4 10 4.2e-07 2.5e-05 24.7 4.9 1 23 264 286 264 286 0.99
5 10 5.7e-05 0.0034 18.0 0.0 1 23 292 314 292 314 0.97
6 10 0.00039 0.023 15.4 1.1 1 23 320 342 320 342 0.96
7 10 7.6e-05 0.0045 17.6 1.0 2 23 434 456 433 456 0.95
8 10 0.00028 0.017 15.8 1.5 1 20 462 481 462 484 0.94
9 10 1.7e-05 0.001 19.7 3.1 1 23 490 512 490 512 0.97
10 10 0.0016 0.095 13.5 0.0 3 23 521 541 519 541 0.92

Sequence Information

Coding Sequence
ATGGAAGATTCCTACATCATTGCGAATTTCCACGCGCTATGTCGGCTATGCCTGAACAAAAGTGCGCTCTCGGTGTCGATTTACGGGGCTGCGCCCGATGACGAGGCTAACGTATCGCTAACCTCCAAAATCGCCGAATGCTGTGAACTCCAGATTGATCCTAATGATGGACTGCCAGGAAGAATATGCTACAAATGCTTACTGAAAGTAGACAAATGTTCAAAGTTTAAAATACAATGCATACAGAATGAGAACAGGTTGAGACAAATTACCAATCGTGTCAATGATCTTGATAACTCAAACTCCTCCGAACTTAGTAATTATAACTACAATAACTCTCATGATCAACAGAAACCAAAGCCTGAAGACTATATTGTTGAAGACAGTGTTGTGATGGTGGTAGATCCGAGCCTTGACTATGACTCATCTGAAGAGTCTGAAAGTGTGGAGCAAGTAGAACCAGAGGTCAACAACGAAAGAGACAACAACCCGGAACAAGAAACAAATACAGAATCTTTCTTTAAAAATGTCTCCATGTGTCAATACTGTGATCAAGCTTTTGTGTCTCCAGAGAAATGCAAGGAACATGAAGTTGCATACCATGACCCAAATTTGCCATACAAATGTGTGGAATGTAGCTTAGTATTTGCAGAAAGATCTCAGTTTGTACAACACACTAAACAAGTACATGGCAATGATAAGCCGTATCACTGTCCCGAGTGTGAAAAATGCTTTGGACGCCGCTCAGATTTACGAAAACATTCTATTGTACACACAGGCATTAGACCTTATCAGTGCCATTACTGTTTGAAAAGTTTCTCTCGCAACACAAACTTGAGTAAACATCTTCGAATTCATGCTGGACATAAGCCACATGTGTGTCCACTGTGCCCGAGGAGTTTTGTAGCCAAAGGAGACTTGGCGCGCCATGTACTCATTCACTCTGGTATGAAGCCTTACAGATGTCGAAAGTGCCCTCTCACGTTTGGTCGACGAGATAAGCTCATCAAGCATGAGGTTAAGCATGGCCCTATAACTCCAGAACATAACACATATTATGAGCATAATCAAGATATGCAAGACATGGTTGTCAATGTAAACCCCTTTAGCAACCTAATGACATCTCCTAATCAGAACAATGCTGATGGATCTCAGACAGACTATGACTTACCCAGAGTCCCTGACCACATTTCTGGTGAAAGTAGTTTCAGCAGAGTACAGAAAAATCCTTCTACATCTAAACAACAAAACTCGCCACCAAAAAAGCAGACACTTGCTAAGAATAGACCTAAGAATATAAAATGCCATCAGTGTCCAAAGAGATTTTCATCTTTAGATGCCTACAAGACGCATGTTTCTATAGCTCATATTGGGTCTAGAGTATTTCAATGCAAAGTTTGCTTTAAGAAGTTTGCACGGAAAAGGGAGTTAGATCGTCACACACCCATCCATTCTGGAATGAAGCCGTTCTCTTGCAGTCAGTGTGATAAGAAATTCACTCGGAAAGACAAGCTTGACAAGCATGAGCAGAGTCATGAATGTTTGGTTGTGAATATGCCTTGTATAGAATGTGGTGCCACATTTGAAAAGAAAGCAGATTTAGTTGCCCACATTAAATCTCATTTCACTGACAATTTTGATGATAAAATCTCACAAATTAAGAAAGAAGATGAACCTGAGTTTCAGCTTGATGAAAATTTTTATGATTTAGAAACTTGA
Protein Sequence
MEDSYIIANFHALCRLCLNKSALSVSIYGAAPDDEANVSLTSKIAECCELQIDPNDGLPGRICYKCLLKVDKCSKFKIQCIQNENRLRQITNRVNDLDNSNSSELSNYNYNNSHDQQKPKPEDYIVEDSVVMVVDPSLDYDSSEESESVEQVEPEVNNERDNNPEQETNTESFFKNVSMCQYCDQAFVSPEKCKEHEVAYHDPNLPYKCVECSLVFAERSQFVQHTKQVHGNDKPYHCPECEKCFGRRSDLRKHSIVHTGIRPYQCHYCLKSFSRNTNLSKHLRIHAGHKPHVCPLCPRSFVAKGDLARHVLIHSGMKPYRCRKCPLTFGRRDKLIKHEVKHGPITPEHNTYYEHNQDMQDMVVNVNPFSNLMTSPNQNNADGSQTDYDLPRVPDHISGESSFSRVQKNPSTSKQQNSPPKKQTLAKNRPKNIKCHQCPKRFSSLDAYKTHVSIAHIGSRVFQCKVCFKKFARKRELDRHTPIHSGMKPFSCSQCDKKFTRKDKLDKHEQSHECLVVNMPCIECGATFEKKADLVAHIKSHFTDNFDDKISQIKKEDEPEFQLDENFYDLET