Basic Information

Gene Symbol
-
Assembly
GCA_029619255.2
Location
JAROYC020000007.1:33162955-33163617[+]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 1 6.9e+03 -1.3 0.1 58 66 7 15 3 18 0.73
2 4 0.028 2e+02 3.6 0.5 34 42 50 59 30 78 0.59
3 4 1.5e-16 1e-12 49.4 1.7 7 70 86 149 81 149 0.97
4 4 1.6 1.1e+04 -2.0 0.1 54 60 154 160 151 161 0.81

Sequence Information

Coding Sequence
ATGGCATCAGCTATAGGAAGATGTAAAATATGTGGGGAGCAACTAAGTTACGAACCCGACGATATTACCGCTTTCGGAAAACATCTAATTGAAAAACATAACGAGCAAATAACACACTTCCAATTTACAGGAAATGGCGCTCCTGAAATATGTGCATGTGGATGCGCCTGTGGTTGCAATTgcaatactaaaaaaatttccaaaaaagccTATAAAACTACAGTTGAATCTTGGAAGCAAGGTGTCGTTTCGCAGGAATGCCCGAACTGTGGATTGACTGGACTTCCTTTAATAAGAAAGCAAAGGAATAAAGTTTCTAAAAATTCTTTTGGCACACTTTGTTTAGTAGGCTGTTGGCCGCTTTGTTTCTTACCTTTCCTCTTGGGAGGCTCAGATACGATGTATCTCTTTTGTCAAGAGTGTGGTTATTTCCTCGGTACCTATGACAGAAAAACAGGTCGGATACACCATTCATGTCCCATTGATTCAACTGAGTATGGAGctaaaatttgtaaatgtaaagATGATGGCTTCtag
Protein Sequence
MASAIGRCKICGEQLSYEPDDITAFGKHLIEKHNEQITHFQFTGNGAPEICACGCACGCNCNTKKISKKAYKTTVESWKQGVVSQECPNCGLTGLPLIRKQRNKVSKNSFGTLCLVGCWPLCFLPFLLGGSDTMYLFCQECGYFLGTYDRKTGRIHHSCPIDSTEYGAKICKCKDDGF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
iTF_00956717;
80% Identity
-