zf-LITAF-like
- Domain
- zf-LITAF-like domain
- Group
- Zinc-Coordinating Group
- PFAM
- PF10601
- Desciption
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Rederence
-
- Novel protein domains and repeats in Drosophila melanogaster: insights into structure, function, and evolution. Ponting CP, Mott R, Bork P, Copley RR. Genome Res. 11, 1996-2008, (2001).
- Molecular cloning and characterization of a putative lipopolysaccharide-induced TNF-alpha factor (LITAF) gene homologue from Zhikong scallop Chlamys farreri. Yu Y, Qiu L, Song L, Zhao J, Ni D, Zhang Y, Xu W. Fish Shellfish Immunol. 23, 419-29, (2007).
- Structural classification of zinc fingers: survey and summary. Krishna SS, Majumdar I, Grishin NV. Nucleic Acids Res. 31, 532-50, (2003).
Statistic of Transcription Factors
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Transcription Factor Table
| Gene ID | Insect | Gene Name | Gene Symbol |
|---|---|---|---|
| iTF_00000856 | Abrostola tripartita | Atri015163.1 | - |
| iTF_00000857 | Abrostola tripartita | Atri020245.1 | Litaf |
| iTF_00000858 | Abrostola tripartita | Atri015164.1 | - |
| iTF_00000859 | Abrostola tripartita | Atri021958.1 | litaf |
| iTF_00000860 | Abrostola tripartita | Atri021957.1 | - |
| iTF_00000855 | Abrostola tripartita | Atri003711.1 | - |
| iTF_00000861 | Abrostola tripartita | Atri004870.1 | - |