Basic Information

Gene Symbol
-
Assembly
GCA_902655005.1
Location
LR737395.1:3791990-3792653[+]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 1.4 2.6e+03 -1.3 0.1 58 66 7 15 3 18 0.71
2 4 0.05 96 3.3 0.5 30 39 50 59 30 67 0.50
3 4 1.6e-16 3.1e-13 49.7 1.4 7 70 87 150 82 150 0.97
4 4 2.3 4.4e+03 -2.0 0.1 54 60 155 161 152 162 0.81

Sequence Information

Coding Sequence
ATGGCATCAGCTataggaaaatgtaaaatatgtggGGAGCAATTAAGTTACGAACCTGACGATATTACCGCTTTCGGAAAACATCTAATTGAAAAACATAACGAGCAGATAACACATTTCCAATTTACAGGAAATGGCGCTCCTGAAATATGTGCATGTGGATGCGCCTGTGGATGCAACTGCAATCTGAATAAAAGAATCTCCAGAAAGGGCTATAAAACTACAGTTGAAACTTGGAAGCAAGGTGTGGTTTCTCAGGAATGTCCAAACTGTGGATTAACTGGGCTTCctttaataagaaaacaaaggaATAAAGTTTCTAGAAATTCTTTTGGTACACTTTGTTTAGTGGGCTGTTGGCCGCTTTGCTTCTTACCTTTCCTCCTGGGAGGCTCAGATACGATGTATCTCTTTTGTCAAGAGTGTGGTTATTTCCTGGGTACCTACGATAGAAAAACAGGCCGGATACATCATTCGTGTCCTATTGATTCCACTGAGTATGGAgctaaaatttgtaaatgtaaagaTGAAGGCTTctag
Protein Sequence
MASAIGKCKICGEQLSYEPDDITAFGKHLIEKHNEQITHFQFTGNGAPEICACGCACGCNCNLNKRISRKGYKTTVETWKQGVVSQECPNCGLTGLPLIRKQRNKVSRNSFGTLCLVGCWPLCFLPFLLGGSDTMYLFCQECGYFLGTYDRKTGRIHHSCPIDSTEYGAKICKCKDEGF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00626745;
90% Identity
iTF_00626745;
80% Identity
-