Basic Information

Insect: Drosophila vulcana
Gene Symbol: ush
Assembly: GCA_008042555.1
Location: VNJP01008750.1:30276-35297[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.005 0.68 11.1 0.0 1 20 171 190 171 192 0.90

2 9 0.00024 0.033 15.2 0.7 1 23 248 270 248 270 0.98

3 9 0.083 11 7.3 2.4 2 21 316 335 316 336 0.92

4 9 0.037 5.1 8.4 2.9 2 21 710 729 709 730 0.93

5 9 0.0069 0.94 10.7 0.0 3 21 785 803 783 804 0.91

6 9 0.0045 0.61 11.2 0.0 2 23 871 892 870 892 0.98

7 9 0.0021 0.28 12.3 1.2 1 23 898 920 898 920 0.99

8 9 0.00053 0.072 14.2 0.8 1 23 973 996 973 996 0.96

9 9 0.31 42 5.5 0.5 2 20 1105 1123 1104 1125 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.005	0.68	11.1	0.0	1	20	171	190	171	192	0.90
2	9	0.00024	0.033	15.2	0.7	1	23	248	270	248	270	0.98
3	9	0.083	11	7.3	2.4	2	21	316	335	316	336	0.92
4	9	0.037	5.1	8.4	2.9	2	21	710	729	709	730	0.93
5	9	0.0069	0.94	10.7	0.0	3	21	785	803	783	804	0.91
6	9	0.0045	0.61	11.2	0.0	2	23	871	892	870	892	0.98
7	9	0.0021	0.28	12.3	1.2	1	23	898	920	898	920	0.99
8	9	0.00053	0.072	14.2	0.8	1	23	973	996	973	996	0.96
9	9	0.31	42	5.5	0.5	2	20	1105	1123	1104	1125	0.91

Sequence Information

Coding Sequence: ATGTGTTCGCTGCCACGAGATGTCGAATTTCTGGCGAACCGAGAGGAGATGCAAAGCCGCTTATCCAGCCCGACCATCTCCATGCCACATCCAGAAGAGACTAATAATACCGGGCCTGAGCAGGACTTGGGCGAAACCAATCCGCGGCAGGAGGAGATTGAGGATGAACTGCCACCGGTCAACAGTCCCAGCACTCCGCCCAGAAGCAGCCCCTCCTCGCCGCAACTGATACCCAAGCTGGAGCAGCCCTCGACGCCGCCATCTGAGGCCGAACCCTCGCCCTGTCCCTCACCTTGTCTCACGCCCACCACCATTTCCACCACGCCCAAGCTGCCCAAGCTGCGTCTTAATGCGCTCCTGGCCTCCGATCCCGCCCTCAAGCCCGATGCCAAGGAGCTGACTCTCCCAGAGCCACGTTTGCTGGCCCCTCCGCCGCTGTCCATTAAGCCGGAGGCGCTGCCCTCGCAGGCCGAGGGCCTGGGAGCGGAGCCGCTGATGAAGCCGGCCCGATTCATGTGCCTGCCCTGCGGCATCGCCTTCAGTTCGCCCTCCACGCTGGAGGCCCACCAAGCCTACTATTGCTCTCATAGGAATAAGGATGCGGACGAGGATCAGGCGGGCGGTGACAAGTCGGTAGCTGGCGGAGGTACTGccgccggaggaggaggtggtgcaGCAGGATCGGGAGGAGCAGGATCCTCGTCGGAACCACCGGCCAAAATGGCCAGGACGGGCAAGCAGTACGCCTGCTCGCAGTGCTCCTACAGTGCGGACAAGAAGGTATCCCTCAACCGGCACATGCGGATGCACCAGACCTCCCCGGCGACGCCCACCCTGGTCAGCCTGCCCAATCTCATCCAGAACGGCATACCACCGCCGCCGGGCGTCGTCCAAGTCGCGCCCAGCTCGCTGGAGGAGGCCTCTAGTCAACAGCAGACGGATCGCTACTGCAGCCACTGTGATATCCGCTTCAACAACATCAAGACGTACCGGGCGCACAAGCAACACTACTGCAGCTCCCGACGACCGGATGGCCAGCTCACCCCCAAGCCGGACACAtctcctggcggcggcggtggtggtggtggcgtcgGACCAGGCCCAGCATCCTCCTCTTCGGCATCTGGTGGAGTTCCAGTCCCGCTGTCAGCGGCTCCCGGCAAGCTGAGTCCACAGCAGGCCACAGGAAGGAACAACACGCCAACGCCCGCCATGGTCGCCCTGGGGCATGCCgcagcggctgcggcggcagcggcagcagcagcggctgcctCTCTCCAGGCGCCACCTCACCCGCCGCCGCCCTTCCTGGCACTGCCCACGCATCCCATCATTATTGTGCCCTGCTCGCTGATACGGGCGGCCAGCTTCATTCCGGGACCACTgCCCACTCCCAACTCGGGAATTGTGAATCCGGAGAACACCTGCTTCACCGTGGACAATGGCACAATCAAGCCACTGGCCACCGCCTTGCTGGGTACCGCCCTGGAGCCAGAGCGACCATCGGCACCGTCCTCGGCCGCCGAGGTGCCAGAGCCCAAGAGCAGTCCCCCCGAACCCAAGCGCAAGGAGGCAAGCGGAAGTCGAGAGTCCGCGCCCTTGGATCTCTCGCTGCGTCGTTCGCCGATCTCTCTGAATTCGCTGAGCCTGCGGCAGCGACACCTGCGCTCTGCTCTCCTGGATGTGGAGGAGGCGCTCCTGGGCAGCGTGGGCAAAGACATTGCGGAAGCCTCGGCCGGCGGAAGCGTGACACCCGAGCAGATCGTGTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCGCCCAAGCGACGAACCATCAGTCCCAGGAGCTCCGGAGCCGGCAGCAATGCTTCCATGTCGCCACCTGGTCTGAGTGTGGTGCCCAGCCTGCTGGACATGCGCTCCATGCTGCCAGCGGACTTTGGCTTGTCCGAATCGCTGCTGGCCAAGACCAATCCGGAGCTGGCACTcaagctggcggcggcggcagctgcagcggctgcggTGGCCGGAGGAGGGGCTTCCCAGGCGCAGGCTAGTGTGGGGAATCCTGGAGGAAGTGGAGGTACTACAGGAGGCCCACAGCAACCGCAGATCTACGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAATATTGTTTTCTGCAAGTATGAGAATTATCTGGCGCACAAGCAGCATTACTGCTCCGCCAGAAACCAGGAGGGTTCCGCCGAAGGCGATGCCAAGTCAGCTGTTTCACCAGGAGCCGGGGGAGGGGGAGGGGGAGGATCCAGCAGCGGAGGAGGATCAGAGCCCGCCACATCGGTGGAAACCACACCTGTGGCATACCAGCAACTCATCTGCGCCGCCTGCGGCATCAAGTACACCTCCCTGGACAACCTGCGAGCCCACCAGAATTACTATTGTCCCAAGGGAGGAGCCACAGCTGGAGGAACGGCCACAGATCCGGTGAAGGAGAAGTGTGGCAAGTGCAAGACCCTGCATGAACTGGGTCTCCCTTGTCCAGCACCACTCACAAGTGTCCTCGCGGCACCCACAGCCAACTCTGGCTCCTCCTCGAACTCCTCCTCGCTGGCCGCCGCCTCCAATAGCTTGAACAAGTGTCCAGTTTGCGGCGTGGTTAGTCCCACGGCCGCGCTGGCCAAGAAGCACATGGAGATGCATGGCACCGTGAAGGCCTATCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGAGAGGGATGCGCACCCACATACGCACCCATTTCGACAAGAAGACGACCAGCGAGGTGAACGAGGAGCACTACATGACCTGCATCttccaggaggaggaggagcagggtcAGGGCCGTGTAATCAGCCAGGAGCTGAGTCAGTCGGCAGTCTCGCAGGACTCGGCCATGGATCATCCGCCGCAGTTGTTCAACTGCGATTACTGCAACTACGCCTCCACCTACAAGGGAAATGTGCTGCGCCACATGAAGCTGCTGCACCCGCACGTGGCCCTGATCAGTTCCCCTTCGATTTCGCCGGAGAGCAGGGATCAGGATCCTGTGATCTTGAACTCCACAGCCAGCAACCAGCACTCTGAGGGCTCCAATGGCGAGGCAGCGAGCTTCCACATCAAGTCGGAGCCCTTGGATCCACCCTCGTCCACGTTGAGCCTGGTGCAGGAGAACAACAACTCGTCTCCCATACCAACTCTGACGCCGCACATCAAGGCCGAGCCCATGGACATAGACAGCCTGACGGTGGCCTCACCTTTGggcgccgctgccgccgctgctgctgtggccgCCGCCGAGGTGATGAAGAAATACTGCTCCACCTGCGACATATCCTTCAACTATGTGAAGACCTACCTGGCCCACAAGCAGTTCTACTGCAAGAACAAGCCCCATCGGCCGGAGGCGAGTGATAGTCCCAGTCCGAACCTGGGATTGGGGGGCATGGGCAGTGGCATCGGTgtggccggcggcggcggccagcagAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MCSLPRDVEFLANREEMQSRLSSPTISMPHPEETNNTGPEQDLGETNPRQEEIEDELPPVNSPSTPPRSSPSSPQLIPKLEQPSTPPSEAEPSPCPSPCLTPTTISTTPKLPKLRLNALLASDPALKPDAKELTLPEPRLLAPPPLSIKPEALPSQAEGLGAEPLMKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEDQAGGDKSVAGGGTAAGGGGGAAGSGGAGSSSEPPAKMARTGKQYACSQCSYSADKKVSLNRHMRMHQTSPATPTLVSLPNLIQNGIPPPPGVVQVAPSSLEEASSQQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPDGQLTPKPDTSPGGGGGGGGVGPGPASSSSASGGVPVPLSAAPGKLSPQQATGRNNTPTPAMVALGHAAAAAAAAAAAAAASLQAPPHPPPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPENTCFTVDNGTIKPLATALLGTALEPERPSAPSSAAEVPEPKSSPPEPKRKEASGSRESAPLDLSLRRSPISLNSLSLRQRHLRSALLDVEEALLGSVGKDIAEASAGGSVTPEQIVCAPSLPSSPSMSPSPKRRTISPRSSGAGSNASMSPPGLSVVPSLLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAAVAGGGASQAQASVGNPGGSGGTTGGPQQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEGSAEGDAKSAVSPGAGGGGGGGSSSGGGSEPATSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGATAGGTATDPVKEKCGKCKTLHELGLPCPAPLTSVLAAPTANSGSSSNSSSLAAASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTTSEVNEEHYMTCIFQEEEEQGQGRVISQELSQSAVSQDSAMDHPPQLFNCDYCNYASTYKGNVLRHMKLLHPHVALISSPSISPESRDQDPVILNSTASNQHSEGSNGEAASFHIKSEPLDPPSSTLSLVQENNNSSPIPTLTPHIKAEPMDIDSLTVASPLGAAAAAAAVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPHRPEASDSPSPNLGLGGMGSGIGVAGGGGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00594089;
90% Identity: iTF_00613057; iTF_00594788; iTF_00594786; iTF_00594089; iTF_00527596; iTF_00613748; iTF_00485409; iTF_00488922; iTF_00541334; iTF_00524674; iTF_00478272; iTF_00492505; iTF_00562041; iTF_00489631; iTF_00490336;
80% Identity: -