Basic Information

Insect: Drosophila bocqueti
Gene Symbol: ush
Assembly: GCA_018151655.1
Location: JAECXF010000002.1:19152623-19157474[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0057 0.43 11.1 0.0 1 20 176 195 176 197 0.90

2 9 0.00027 0.021 15.2 0.7 1 23 253 275 253 275 0.98

3 9 0.094 7.1 7.3 2.4 2 21 323 342 323 343 0.92

4 9 0.042 3.2 8.3 2.9 2 21 721 740 720 741 0.93

5 9 0.0078 0.59 10.7 0.0 3 21 794 812 792 813 0.91

6 9 0.0051 0.39 11.2 0.0 2 23 883 904 882 904 0.98

7 9 0.0023 0.18 12.3 1.2 1 23 910 932 910 932 0.99

8 9 0.0006 0.046 14.2 0.8 1 23 976 999 976 999 0.96

9 9 0.35 27 5.4 0.5 2 20 1111 1129 1110 1131 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0057	0.43	11.1	0.0	1	20	176	195	176	197	0.90
2	9	0.00027	0.021	15.2	0.7	1	23	253	275	253	275	0.98
3	9	0.094	7.1	7.3	2.4	2	21	323	342	323	343	0.92
4	9	0.042	3.2	8.3	2.9	2	21	721	740	720	741	0.93
5	9	0.0078	0.59	10.7	0.0	3	21	794	812	792	813	0.91
6	9	0.0051	0.39	11.2	0.0	2	23	883	904	882	904	0.98
7	9	0.0023	0.18	12.3	1.2	1	23	910	932	910	932	0.99
8	9	0.0006	0.046	14.2	0.8	1	23	976	999	976	999	0.96
9	9	0.35	27	5.4	0.5	2	20	1111	1129	1110	1131	0.91

Sequence Information

Coding Sequence: ATGTATTCCAAAGATTTAACCGCTCAAGAGATGGGCAGCGAGGAGAAGGAGCAGCAGCTGGAGGATCAGCTAGATGACGACTCCAGGGATCTCCAAGAGACCAATAATAATAACAACAACAACAGCAATAATAATAACGAAGATGAAGACGACGACGATGACCAGGACGACGCTGTGTTCGAGCAGCCAGAAGAGACTAGTTCCAGGCCCGAGCAGGACTTGGGCGAAACCGATCCGCGGCACGAGGAGATTGAGGACGAACTGCCCGTAAACAGTCCCAGCACTCCGCCCAGAAGCCTGCCCTCCTCGCCGCAACTGATACCCAAGCTGGAGCAGCCTTCCACGCCGCCCTCGGAGGCCGAACCCTCGCCCTGTCCCTCACCTTGTCTCACGCCCAAGCTGCCCAAGCTGCGTCTCAATGCGCTCCTGGCCTCCGATCCCGCCCTCAAGCCCGACGCCAAGGAGTTAACTCTCCCCGAGCCACAGGGAGGCCTGGGAGCGGAGCCGCTGATGAAGCCAGCCCGATTCATGTGCCTGCCCTGCGGCATCGCCTTCAGTTCGCCCTCCACGCTGGAGGCCCACCAAGCCTACTATTGCTCTCATCGGAACAAGGATGCGGACGAGGATCAGGCGGGCAGCGACAAGTCTGGCGGAGGTACTGCCGCCGGCGGAGGTGGTGGTGCCGCAGGACCAGGAGGCGGCGGAGCAGGATCCTCGTCGGAACCACCGGCCAAAATGGCCAGGACGGGCAAGCAGTACGCCTGCTCGCAGTGCTCCTACAGCGCGGACAAGAAGGTCTCCCTCAACCGGCACATGCGCATGCACCAGACCTCCCCGGCGACGCCCACCCTGGTCAGCCTGCCCAATCTCATCCAGAACGGCATTCCACCGCCGCCGGGCGTCGTCGTCGTCGGCGCGCCCAGCTCGCTGGAGGAGGCCTCTAGTCAACAGCAGCAGACGGATCGCTACTGCAGCCACTGTGATATCCGCTTCAACAACATCAAGACGTACCGGGCGCACAAGCAGCACTACTGCAGCTCCCGGCGACCGGATGGCCAGCTCACGCCCAAGCCGGACACATCTCCTGGAGGCGGTGGTGGTGGTGGTGGTGGCGTGGGACCAGGCCCAGCCTCCTCCTCCTCCGCATCTGGCGGAGGAGTCCCGGCCCCCCTGTCAGCGGCTCCCGGCAAGCTGAGTCCACAGCAGGCCACTGGCCACAGGAACAACAAGACGCCAACGCCCGCCATGGTCGCCCTGGGACATGCCGCAGCGGCGGCGGCGGCGGCGGCAGCAGCAGCGGCCGCCTCTCTCCAGGCGCCACCCCACCCGCCGCCGCCCTTCCTGGCACTGCCCACGCACCCGATCATCATTGTGCCCTGCTCGCTGATCCGGGCGGCCAGCTTCATTCCGGGACCACTGCCCACTCCCAACTCGGGAATTGTGAATCCGGAGAACACCTGCTTCACCGTGGACAATGGCACCATCAAGCCACTGGCCACCGCCCTGCTGGGCTCTGCCCTGGAGCCAGAGCGACCCTCGGCACCCTCATCGGCAGTGGCAGTCGAGGTGCCAGAGCCCAAGAGCAGTCCCCCCGAACCCAAGCGCAAGGAGGCAGGCGGAAGCCGTGAATCCGCGCCCTTGGATCTCTCGCTGCGTCGTTCGCCGATCTCCCTGAACTCGCTGAGCCTGCGGCAGCGACACCTGCGCTCCGCTCTCCTGGATGTGGAGGAGGCGCTGCTGGGCAGCGTGGGCAAAGAGATTGCGGAAGCCTCGGCCGGCGGCAGCGTGACGCCCGAACAGATCGTGTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCGCCCAAGCGACGAACCATCAGTCCCCGGAGCTCCGGCGCGGGCAGCAATGCTTCCATGTCGCCACCTGGCTTGAGTGTGGTGCCCAGCCTGCTGGACATGCGCGCCATGCTGCCAGCGGACTTTGGATTGTCCGAATCGCTGCTGGCCAAGACCAATCCGGAGCTGGCTCTCAAGCTGGCGGCAGCGGCAGCTGCAGCGGCTGCGGTGGCCGGCGGAGGAGGTGCTTCCCAGGCGCAGGCTCCGCAGGGAAGCGGAGGCGGCACTAGTGGAGCCCCACAGCAGCCGCAGATCTACGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAACATTGTCTTCTGCAAATATGAGAATTACCTGGCGCACAAGCAGCACTACTGCTCCGCCAGAAACCAGGAGGGTTCCGCCGAGGGGGATGCCAAGTCAGCTGTTTCGCCAGGAGCCGGCGGGAGCGGAGGATCCAGCGTCGGGGGTGGATCAGAGCCCGCCACATCGGTGGAAACCACACCGGTGGCGTACCAGCAACTCATCTGCGCCGCCTGCGGCATCAAGTACACCTCCCTGGACAACCTGCGAGCCCACCAGAACTACTATTGCCCGAAGGGAGGAGCCACAGCCGGGGGAACACCCAGCGATCCGGTGAAGGAGAAGTGTGGCAAGTGCAAGACGCTGCATGAGCTGGGCCTGCCTTGCCCGGCGCCACTCACCAGCGTCCTCGCGGCACCCACAGCCAACTCTGGCTCCTCCTCGAACTCCTCCTCGCTCGCCGCCGCCGCCTCCGCCTCCAATAGCCTGAACAAGTGTCCCGTTTGTGGCGTGGTGAGTCCCACGGCCGCGCTGGCCAAGAAGCACATGGAGATGCATGGCACCGTGAAGGCCTACCGCTGCAGCATCTGCCAGTACAAGGGCAACACTCTAAGGGGGATGCGCACCCACATACGCACCCATTTCGACAAGAAGACGACCAGCGAGGTGAACGAGGAGCACTACATGACCTGCATCTTCCAGGAGGAGGAGCAGGAGCAGCAGGGTCAGGGTCGTGTGATCAGCCAGGAGCTGAATCATCCGCCGCAGTTGTTCAACTGCGATTACTGCAACTACGCCTCCACCTACAAGGGCAATGTGCTGCGCCACATGAAGCTGCTGCATCCGCACGTGGCCCTCATCAGTTCCCCCTCGATTTCGCCGGAGAGCAGGGATCAGGATTCAGGGATCTTGAACTCCACGGCCAGCAACCAGCACTCTGAGGGCTCCAATGGCGAGGCAGCGAGCTTCCACATCAAGTCCGAGCCCTTGGATCCACCCTCGTCCACGCTGAGCCTGGTGCAGGAGAACAACAACTCGTCCCCCCTACCAACCCTGACGACGCCGCACATCAAGGCCGAGCCCATGGACATGGACAGCCTGACGACGGTGGCCTCCTCACCCCTGGGCGCCGCTGCAGCCGCTGCTGCCGTGGCCGCCGCCGAGGTGATGAAGAAATACTGCTCCACCTGCGACATATCCTTCAACTACGTGAAGACCTACCTGGCCCACAAGCAGTTCTACTGCAAGAACAAGCCCCATCGACCGGAGGCCAGCGATAGTCCCAGTCCGAACCTGGGAAGCATGGGCAGTGGCCTCGGTGTGGCGGCCGGCGGCGGCGGCGGCCAGCAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MYSKDLTAQEMGSEEKEQQLEDQLDDDSRDLQETNNNNNNNSNNNNEDEDDDDDQDDAVFEQPEETSSRPEQDLGETDPRHEEIEDELPVNSPSTPPRSLPSSPQLIPKLEQPSTPPSEAEPSPCPSPCLTPKLPKLRLNALLASDPALKPDAKELTLPEPQGGLGAEPLMKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEDQAGSDKSGGGTAAGGGGGAAGPGGGGAGSSSEPPAKMARTGKQYACSQCSYSADKKVSLNRHMRMHQTSPATPTLVSLPNLIQNGIPPPPGVVVVGAPSSLEEASSQQQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPDGQLTPKPDTSPGGGGGGGGGVGPGPASSSSASGGGVPAPLSAAPGKLSPQQATGHRNNKTPTPAMVALGHAAAAAAAAAAAAAASLQAPPHPPPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPENTCFTVDNGTIKPLATALLGSALEPERPSAPSSAVAVEVPEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISLNSLSLRQRHLRSALLDVEEALLGSVGKEIAEASAGGSVTPEQIVCAPSLPSSPSMSPSPKRRTISPRSSGAGSNASMSPPGLSVVPSLLDMRAMLPADFGLSESLLAKTNPELALKLAAAAAAAAAVAGGGGASQAQAPQGSGGGTSGAPQQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEGSAEGDAKSAVSPGAGGSGGSSVGGGSEPATSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGATAGGTPSDPVKEKCGKCKTLHELGLPCPAPLTSVLAAPTANSGSSSNSSSLAAAASASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTTSEVNEEHYMTCIFQEEEQEQQGQGRVISQELNHPPQLFNCDYCNYASTYKGNVLRHMKLLHPHVALISSPSISPESRDQDSGILNSTASNQHSEGSNGEAASFHIKSEPLDPPSSTLSLVQENNNSSPLPTLTTPHIKAEPMDMDSLTTVASSPLGAAAAAAAVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPHRPEASDSPSPNLGSMGSGLGVAAGGGGGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00594089;
90% Identity: iTF_00617860;
80% Identity: -