Basic Information

Insect: Drosophila kikkawai
Gene Symbol: ush
Assembly: GCA_018152535.1
Location: NW:27622047-27705756[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0063 0.38 11.0 0.0 1 20 225 244 225 246 0.90

2 9 0.00031 0.018 15.2 0.7 1 23 304 326 304 326 0.98

3 9 0.1 6.2 7.2 2.4 2 21 370 389 370 390 0.92

4 9 0.047 2.8 8.3 2.9 2 21 765 784 764 785 0.93

5 9 0.0087 0.52 10.6 0.0 3 21 838 856 836 857 0.91

6 9 0.0057 0.34 11.2 0.0 2 23 925 946 924 946 0.98

7 9 0.0026 0.15 12.3 1.2 1 23 952 974 952 974 0.99

8 9 0.00067 0.04 14.1 0.8 1 23 1026 1049 1026 1049 0.96

9 9 0.39 23 5.4 0.5 2 20 1159 1177 1158 1179 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0063	0.38	11.0	0.0	1	20	225	244	225	246	0.90
2	9	0.00031	0.018	15.2	0.7	1	23	304	326	304	326	0.98
3	9	0.1	6.2	7.2	2.4	2	21	370	389	370	390	0.92
4	9	0.047	2.8	8.3	2.9	2	21	765	784	764	785	0.93
5	9	0.0087	0.52	10.6	0.0	3	21	838	856	836	857	0.91
6	9	0.0057	0.34	11.2	0.0	2	23	925	946	924	946	0.98
7	9	0.0026	0.15	12.3	1.2	1	23	952	974	952	974	0.99
8	9	0.00067	0.04	14.1	0.8	1	23	1026	1049	1026	1049	0.96
9	9	0.39	23	5.4	0.5	2	20	1159	1177	1158	1179	0.91

Sequence Information

Coding Sequence: ATGTCACGACGCAAACAGTCCAATCCCAAGCCGTTGAATAAAGGTGATTGTTCCGATACCACAGAAGACATGACTGTCGACAGCAGAGATTCCAAAGATTTGACCGCTCAAGAGATGGGCagcgaggagaaggagcagcagcagctggaggatCAGCTGGATGACGACTCCCGGGATCTCCAAGAGaccaacaataataacaataacaataataataataacgaagATGAAGACGAAGATGACCAGGACGACGCTGTATTTGAGCAGCCAGATGAGACTAATGCCGCGCCTGATCAGGATCTGGGCGAGACCGATCCGCGGCAGGAGGAGATTGAAGACGAACTACCCGTCAACAGTCCCAGCACTCCGCCCAGGAGCAGCCCCTCCTCGCCGCAGCTGATACCCAAGCTGGAGCAGCCTTCGACGCCGCCATCCGAGGCCGAACCCTCGCCCTGTCCCTCACCCTGTCCCACGCCCACCAGCACGCCCAAGTTGCCCAAGCTGCGTCTGAATGCGCTCCTGGCCTCCGATCCCGCCCTCAAGCCCGATGCCAAGGAGCTGACTCTACCAGAGCCTCGCCTGCTGGCACCTCCGTCGGTGTCCATAAAGCCGGAGGCGCCGCCATCGCAGGCCGAGAACCTGGGAGCGGAGCCGCTGATGAAGCCAGCCCGTTTCATGTGCCTCCCCTGCGGTATCGCCTTCAGTTCGCCCTCCACGCTGGAGGCTCACCAGGCCTACTATTGCTCTCATAGGAACAAGGAGGCGGACGAGGATCAGGCGGGCAGTGACAAGTCAGTGACGGGCGGTGGATCTGCCTCCGGAGGAGGCGGGGCCGCGGGAccgggaggaggaggaggaggaggatcctCGTCGGAACCACCGGCCAAAATGGCCAGAACGGGCAAGCAGTACGCCTGCTCGCAGTGCTCCTACAGTGCGGATAAGAAGGTGTCCCTCAACCGGCACATGCGGATGCACCAGACCTccccggccacgcccaccttGGTCAGCCTGCCCAATCTCATCCAGAACGGCATACCACCGCCGCCGGGCGTCGTGGTCGCGCCCAACTCGCTGGAGGAGGCCTCTAGTCAACAGACGGATCGCTACTGCAGCCACTGTGATATCCGCTTCAACAACATCAAGACGTACCGGGCGCACAAGCAGCACTACTGCAGCTCCCGGCGGCCGGATGGCCAGCTCACCCCCAAGCCGGACACCTCTCCTGGCggcggaggtggtggtggcgtGGGACCAGGcccatcctcctcctcctcggcatCAGGTGGAGTCCCTGGAGCCACCCTGTCAGCGGCGGCTCCTGGCAAGCTGAGTCCACAGGCCAGCAGGAACAACAAGACGCCAACGCCCGCCATGGTGGCCTTGGGCCATGccgcagcggcggcggcggcggcggcagctgcagcggcTGCCTCTCTTCAGGCGCCGCCTCACCCGCCGCCGCCCTTTCTAGCGTTGCCCACGCATCCGATCATCATTGTGCCCTGCTCGCTGATACGGGCGGCCAGCTTCATTCCGGGGCCACTGCCCACTCCCAACTCGGGAATAGTGAATCCGGAGAACACCTGCTTCACCGTGGACAATGGAACCTTCAAGCCACTGGCCACCGCCCTGCTGGGTACTGCCCTAGAGCCAGAGCGACCCTCGGCACCCTCATCTGCAGCCGAGGTGCCAGAACCCAAGAGCAGTCCTCCCGAGCCCAAGCGCAAGGAGGCGGGCGGAAGTCGAGAGTCTGCGCCCTTGGATCTCTCACTGCGCCGTTCGCCCATCTCTCTGAACTCGCTGAGCCTGCGGCAGCGACACCTGCGCTCTGCTCTCCTCGATATGGAGGAGGCGCTGCTGGGCAACGTGGGCAAAGAGATTGCAGAAACCTCGGCTGGCGGAAGCGTGACTCCCGAACAGATCGTGTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCGCCCAAGCGGCGAACCATCAGTCCCCGGAGCTCTGGAGCCGGCAGCAATGCCTCCATGTCGCCACCTGGCCTGGGTGTGGTACCCAGCCTGCTGGACATGCGCTCCATGCTGCCAGCGGACTTTGGCTTGTCCGAATCCCTGCTGGCCAAGACCAATCCGGAGTTGGCCCTCAagctggcggcggcggcagctgcggcggctgcagTGGCCGGAGGAGGAGGTCCTTCCCAGGCGCAGGCTAGTGTAGGGAATCCCGGGGGAAGTGGAGCCACTGCAGGAGCCCCCCAGCAACCGCAGATATATGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAATATCGTTTTCTGCAAATATGAGAATTACCTGGCGCACAAGCAGCATTACTGCTCCGCCAGGAACCAGGAGGGTTCCGCTGATGGCGATGCCAAGTCGGCTGTCTCGCCAGGAGCCGGCGGAGCCGGAGGTTCTAGCGTGGGAGGAGGATCAGAGCCTGCCACTTCGGTGGAAACAACACCGGTGGCGTACCAGCAACTCATCTGCGCCGCCTGCGGCATCAAATACACCTCCCTGGACAACCTGCGAGCCCACCAGAACTACTACTGTCCCAAGGGAGGAGCCACGGCTGGAGGAACGCCCTCAGATCCGGTCAAGGAGAAGTGTGGCAAGTGCAAGACCCTTCACGAACTGGGCCTCCCTTGTCCAGCGCCACTCACCAGTGTCCTGGCGGCACCCACAGCCAACTCCGGCTCCTCCTCCGCGAACTCCTCTTCGCTGGCCGCCGCCTCCAATAGCCTGAACAAGTGCCCTGTCTGTGGTGTGGTGAGTCCCACGGCGGCGCTGGCCAAGAAGCACATGGAGATGCATGGCACCGTGAAGGCCTACCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGCGGGGGATGCGCACCCACATACGCACCCATTTCGACAAGAAGACCACCAGCGAGGTGAACGAGGAGCACTTCATGACTTGCATCtttcaggaggaggaggagcagcagcagcagcagcagggtcGTGCAATCAGCCAGGAGCTAAGGGAGCAGGAGTCGGCCATGGATCATCCGCCGCAGTTGTTCAACTGCGATTACTGCAACTACGCCTCCACCTACAAGGGCAATGTGCTGCGCCACATGAAGCTGCTGCATCCGCACGTGGCCCTCATCAGTTCCCCCTCGATTTCGCCGGAGTGCAGGGATCAGGATTCAGTGATCTTGAACTCGACAGCCAGCAACCAGCACTCCGAGGGCTCCAATGGCGAGGCAGCCAGCTTCCACATCAAGTCCGAGCCCTTGGATCCACCCTCGTCCACGCTGAGCCTGGTCCAGGAGAACAACAACTCCTCTCCCGTGCCCACCCTGACGCCACACATCAAGGCCGAGCCCATGGACATTGATAGCCTGACGACGGTGGCCTCACCCTTAGGAGCCGCtgcagccgctgctgctgtggccgCCGCCGAGGTGATGAAGAAGTACTGCTCCACATGCGACATATCCTTCAACTATGTGAAGACCTACCTGGCCCACAAGCAGTTCTACTGCAAGAACAAGCCCCATCGGCCGGAGGTCAGCGATAGTCCCAGTCCGAACCTGGGAATGGGTGGTCTTAGCAGTGGCATCGGCGtagccggcggcggcggccagcAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MSRRKQSNPKPLNKGDCSDTTEDMTVDSRDSKDLTAQEMGSEEKEQQQLEDQLDDDSRDLQETNNNNNNNNNNNEDEDEDDQDDAVFEQPDETNAAPDQDLGETDPRQEEIEDELPVNSPSTPPRSSPSSPQLIPKLEQPSTPPSEAEPSPCPSPCPTPTSTPKLPKLRLNALLASDPALKPDAKELTLPEPRLLAPPSVSIKPEAPPSQAENLGAEPLMKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKEADEDQAGSDKSVTGGGSASGGGGAAGPGGGGGGGSSSEPPAKMARTGKQYACSQCSYSADKKVSLNRHMRMHQTSPATPTLVSLPNLIQNGIPPPPGVVVAPNSLEEASSQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPDGQLTPKPDTSPGGGGGGGVGPGPSSSSSASGGVPGATLSAAAPGKLSPQASRNNKTPTPAMVALGHAAAAAAAAAAAAAASLQAPPHPPPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPENTCFTVDNGTFKPLATALLGTALEPERPSAPSSAAEVPEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISLNSLSLRQRHLRSALLDMEEALLGNVGKEIAETSAGGSVTPEQIVCAPSLPSSPSMSPSPKRRTISPRSSGAGSNASMSPPGLGVVPSLLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAAVAGGGGPSQAQASVGNPGGSGATAGAPQQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEGSADGDAKSAVSPGAGGAGGSSVGGGSEPATSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGATAGGTPSDPVKEKCGKCKTLHELGLPCPAPLTSVLAAPTANSGSSSANSSSLAAASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTTSEVNEEHFMTCIFQEEEEQQQQQQGRAISQELREQESAMDHPPQLFNCDYCNYASTYKGNVLRHMKLLHPHVALISSPSISPECRDQDSVILNSTASNQHSEGSNGEAASFHIKSEPLDPPSSTLSLVQENNNSSPVPTLTPHIKAEPMDIDSLTTVASPLGAAAAAAAVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPHRPEVSDSPSPNLGMGGLSSGIGVAGGGGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00594089;
90% Identity: iTF_00617860;
80% Identity: -