Basic Information

Insect: Drosophila bakoue
Gene Symbol: ush_1
Assembly: GCA_008044335.1
Location: VNJL01015590.1:50294-55138[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0062 0.74 11.0 0.0 1 20 250 269 250 271 0.90

2 9 0.0003 0.036 15.1 0.7 1 23 327 349 327 349 0.98

3 9 0.1 12 7.2 2.4 2 21 394 413 394 414 0.92

4 9 0.046 5.5 8.3 2.9 2 21 783 802 782 803 0.93

5 9 0.0085 1 10.6 0.0 3 21 856 874 854 875 0.91

6 9 0.0056 0.67 11.1 0.0 2 23 944 965 943 965 0.98

7 9 0.0025 0.3 12.2 1.2 1 23 971 993 971 993 0.99

8 9 0.00065 0.078 14.1 0.8 1 23 1047 1070 1047 1070 0.96

9 9 0.39 46 5.4 0.5 2 20 1180 1198 1179 1200 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0062	0.74	11.0	0.0	1	20	250	269	250	271	0.90
2	9	0.0003	0.036	15.1	0.7	1	23	327	349	327	349	0.98
3	9	0.1	12	7.2	2.4	2	21	394	413	394	414	0.92
4	9	0.046	5.5	8.3	2.9	2	21	783	802	782	803	0.93
5	9	0.0085	1	10.6	0.0	3	21	856	874	854	875	0.91
6	9	0.0056	0.67	11.1	0.0	2	23	944	965	943	965	0.98
7	9	0.0025	0.3	12.2	1.2	1	23	971	993	971	993	0.99
8	9	0.00065	0.078	14.1	0.8	1	23	1047	1070	1047	1070	0.96
9	9	0.39	46	5.4	0.5	2	20	1180	1198	1179	1200	0.91

Sequence Information

Coding Sequence: ATGTGTTCGCTGCCACGAGATGTCGAATTTCTGGCGAACCGAGGAGATGCAGAGCCGCTTATCCTGCCCGACCATCTCCATGCCACATGTGTGTGCCATCTCCGCGTCCagagccagtgccagtgccaggcCGCCATAATCTCGGCCAGCATCGCCGTTGATTCCAAAGATTTGACCACTCAAGAGATGGGCagcgaggagaaggagcagcagcagctggaggatcAACTGGATGACGACTCCAGGGATCTCCAAGagaccaataataataacaataacaacaataataataacgaagATGAAGACGACGATGACCGGGACGATGATGTGTTCGAGCAGCCAGAAGAGACTAATACCGGGCCTGAGCAGGACTTGGGCGAAACCGATCCGCGGCAGGAGCAGATTGAGGACGAACTGCCGGTCAACAGTCCCAGCACTCCGCCCAGGAGCAGCCCCTCCTCGCCGCAACTGATACCCAAGCTGGAGCAGCCTTCCACGCCGCCATCCGAGGCCGAGCCCTCGCCCTGTCCCTCGCCTTGCCTCacgcccaccaccaccacgcccAAGCTGCCCAAGTTGCGGCTCAATGCGCTCCTGGCCTCCGATCCCGCCCTCAAGCCCGATGCCAAGGAGCTGACTCTCCCAGAGCCACGTCTGCTGGCCCCTCCGCCGCTGTCCATTAAGCCGGAGGCGCCGCCATCGCAGGCAGAGAGCCTGGGAGCGGAGCCGCTGATGAAGCCAGCCCGATTCATGTGCCTGCCCTGCGGCATCGCCTTCAGTTCGCCCTCCACGCTGGAGGCCCACCAAGCCTACTATTGCTCTCATAGGAATAAGGATGCGGACGAGGATCAGGCGGGCAGTGACAAGTCGGTAGCTGGCGGAGGTTCTGCCGCCGGAGGAGGTGGTGCTGCAGGATCGGGAGGTGGAGCAGGATCCTCGTCGGAACCACCGGCCAAGATGGCCAGGACGGGCAAGCAGTACGCCTGCTCGCAGTGCTCCTACAGTGCGGACAAGAAGGTGTCCCTCAACCGGCACATGCGGATGCACCAGACCTCTCCGGCGACGCCCACCCTGGTCAGCCTGCCCAATCTCATCCAGAACGGCATAGCACCGCCGCCGGGCGTCGTCGTCGCGCCCAGCTCGCTGGAGGAGGCCTCTAGTCAAcagcagaCGGATCGCTACTGCAGCCACTGTGATATCCGCTTCAACAACATCAAGACGTACCGGGCGCACAAGCAGCACTACTGCAGCTCCCGGCGGCCGGACGGCCAGCTCACGCCCAAGCCGGACACATCtcctggcggcggtggcggcgtgGGACCAGGcccagcctcctcctcctccgcatcTGGCGGAGTCCCAGCCCCCCTGTCAGCGGTTCCCGGCAAGCTGAGTCCACAGGCCAGCAGGAACAACAAGACGCCAACGCCCGCCATGGTCGCCCTGGGGCATgccgcagcggctgcagcggcggcagcagcagcggctgcctCTCTCCAGGCGCCACCtcatccgccgccgcccttcCTCGCACTGCCCACGCATCCGATCATCATTGTGCCCTGCTCGCTGATACGGGCTGCCAGCTTCATTCCGGGTCCACTGCCCACTCCCAACTCGGGAATTGTGAATCCGGAGAACACCTGCTTCACCGTGGACAATGGAACGATCAAGCCACTGGCCACCGCCTTGCTGGGCACCGCCCTGGAGCCAGAGCGACCCTCGGCACCCTCGTCCGCAGCCGAGGTGCCAGAGCCCAAGAGCAGTCCCCCCGAACCCAAGCGCAAGGAGGCGGGCGGAAGTCGAGAGTCTGCGCCCTTGGATCTCTCGCTGCGTCGTTCGCCGATCTCTTTGAACTCGCTGAGCCTGCGGCAGCGACACCTGCGCTCTGCTCTTCTGGATGTGGAGGAGGCGCTCCTGGGCAGCGTAGGCAAAGATATTGCGGAAGCCTCGGCCGGCGGAAGCGTGACTCCCGAACAGATCGTGTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCGCCCAAGCGACGAACCATCAGTCCCCGGAGCTCTGGAGCCGGCAGCAATGCTTCCATGTCGCCACCTGGCCTGAGTGTGGTGCCCAGCCTGCTGGACATGCGCTCCATGCTGCCAGCGGACTTTGGCTTGTCCGAATCGCTGCTGGCCAAGACCAACCCGGAGTTGGCGCTcaagctggcggcggcggcagctgcagccgctgcgGTGGCCGGAGGAGGTGCTTCCCAGGCGCAGGCTAGTGTGGGGAATCCTGGAGGAAGTGCCGCAACGACTGGTGCCCCTCAGCAGCCTCAGATCTACGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAACATTGTCTTCTGCAAATATGAGAATTACCTGGCGCACAAGCAGCATTACTGCTCCGCCCGAAACCAAGAGGGTTCCGCCGAAGGGGATGCCAAGTCAGCCGTCTCACCAGGAGCCGGGGGAGCCGGAGGATCCAGCGTCGGGGGAGGATCAGAACCGGCCACATCGGTGGAAACCACACCAGTGGCGTACCAGCAACTCATCTGCGCCGCCTGCGGCATCAAGTACACCTCCCTGGACAACCTGCGAGCCCACCAGAACTACTATTGTCCCAAGGGAGGAGCCACTGCCGGAGGAACGCCCACCGATCCGGTGAAGGAGAAGTGTGGCAAGTGCAAGACCCTGCATGAACTGGGCCTCCCTTGTCCAGCGCCACTCACAAGTGTCCTCGCGGCACCCACAGCCAactccggctcctcctcctcctcgaactCCTCCTCGCTGTCCGCCGCCTCCAATAGCCTGAACAAATGTCCCGTTTGCGGCGTAGTGAGCCCCACGGCAGCGCTGGCCAAGAAGCACATGGAGATGCATGGCACCGTGAAGGCCTATCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGAGGGGGATGCGCACCCACATACGCACCCATTTCGACAAGAAGACGACCAGCGAGGTGAACGAGGAGCACTACATGACCTGCATCttccaggaggaggaggagcagcagggtCAATGTCGTGCCATCAGCCAGGAGCTGAGTCAGTCGGCAGTCCCGCAGGACTCAGCCATGGATCATCCGCCGCAGTTGTTCAACTGCGATTACTGCAACTACGCCTCCACCTACAAGGGCAATGTGCTGCGTCACATGAAGCTGCTGCATCCGCACGTGGCCCTGATCAGTTCGCCCTCGATTTCGCCGGAGAGCAGGGACCAGGACCCTGTAATTTTGAACTCCACAGCCAGCAACCAGCACTCTGAGGGCTCCAATGGCGAGGCAGCAGCGAGCTTCAACATCAAGTCCGAGCCCTTGGATCCACCCTCGTCCACGCTGAGCCTGGTGCAGGAGAACAACAATTCGTCTCCCGTACCAACCCTGACGCCGCACATCAAGGCCGAGCCCATGGACATAGACAGCCTGACGGTGGCCTCACCTTTGGGcgccgctgcagccgccgctgctgtGGCCGCCGCCGAGGTGATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTATGTGAAGACCTACCTGGCCCACAAGCAGTTCTACTGCAAGAACAAGCCCCATCGCCCGGAGGCCAGTGATAGTCCCAGTCCGAACCTGGGAATGGGGAGCCTGGGCAGTGGCATCGGTgtggccggcggcggcgggcagcAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MCSLPRDVEFLANRGDAEPLILPDHLHATCVCHLRVQSQCQCQAAIISASIAVDSKDLTTQEMGSEEKEQQQLEDQLDDDSRDLQETNNNNNNNNNNNEDEDDDDRDDDVFEQPEETNTGPEQDLGETDPRQEQIEDELPVNSPSTPPRSSPSSPQLIPKLEQPSTPPSEAEPSPCPSPCLTPTTTTPKLPKLRLNALLASDPALKPDAKELTLPEPRLLAPPPLSIKPEAPPSQAESLGAEPLMKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEDQAGSDKSVAGGGSAAGGGGAAGSGGGAGSSSEPPAKMARTGKQYACSQCSYSADKKVSLNRHMRMHQTSPATPTLVSLPNLIQNGIAPPPGVVVAPSSLEEASSQQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPDGQLTPKPDTSPGGGGGVGPGPASSSSASGGVPAPLSAVPGKLSPQASRNNKTPTPAMVALGHAAAAAAAAAAAAASLQAPPHPPPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPENTCFTVDNGTIKPLATALLGTALEPERPSAPSSAAEVPEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISLNSLSLRQRHLRSALLDVEEALLGSVGKDIAEASAGGSVTPEQIVCAPSLPSSPSMSPSPKRRTISPRSSGAGSNASMSPPGLSVVPSLLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAAVAGGGASQAQASVGNPGGSAATTGAPQQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEGSAEGDAKSAVSPGAGGAGGSSVGGGSEPATSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGATAGGTPTDPVKEKCGKCKTLHELGLPCPAPLTSVLAAPTANSGSSSSSNSSSLSAASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTTSEVNEEHYMTCIFQEEEEQQGQCRAISQELSQSAVPQDSAMDHPPQLFNCDYCNYASTYKGNVLRHMKLLHPHVALISSPSISPESRDQDPVILNSTASNQHSEGSNGEAAASFNIKSEPLDPPSSTLSLVQENNNSSPVPTLTPHIKAEPMDIDSLTVASPLGAAAAAAAVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPHRPEASDSPSPNLGMGSLGSGIGVAGGGGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00594089;
90% Identity: iTF_00617860;
80% Identity: -