Dvii005986.1
Basic Information
- Insect
- Drosophila virilis
- Gene Symbol
- ftz-f1
- Assembly
- GCA_007989325.2
- Location
- CM017606.2:20186197-20233105[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.022 1.6e+02 1.1 7.7 42 93 34 86 12 227 0.63 2 4 0.083 5.8e+02 -0.7 11.3 32 91 325 382 282 405 0.61 3 4 2.4e-19 1.7e-15 57.0 0.5 1 79 560 637 560 658 0.75 4 4 4.2e-72 2.9e-68 230.8 1.1 157 408 776 1020 745 1022 0.91
Sequence Information
- Coding Sequence
- ATGGATACCTTTAATGTACCTTTGCTGgccgagagcagcagcagcagcagcattgccaATTATgcggccagcaacaacaacgatagcaacaatcatcatcatcaacagcatcagcatcagaatcatcatcatcaccagcacctgcaacagcaacagcaacaacaacaacaacaacaacaacagcagctgcagcagcagcagcatcagcagccagtgttgccacatCATCATAAGGATCAGATGCTCGCCGCGGGCAGCACACCAATGTTGCCATTCATTAACTATGCCCAGCTGCAAAAGGACGCGCTGcccaattccaattccaatccGCCCATTGAGAACTTTAGTTCCTTGCAGGCCATCGACAACAGTCAATTGGATGGCGCCGTCTCCTTGAGCGGACTCTGTGAGCGCATCTTTGCCAGTCCCAATCCGCATAGTAATagcaatcacaacaacaacaacaacaacaatgtggaTGTTAAAGGGTCAGCGCCATCTAGCGGCGGCAACGGGCCGCTTATACTAGAATCCGTCTCCATGTCATCATTTGCCAATATTCTGTTCAACAACaatcgcagcaacaacaacaacaacaacaacagcagccagaaCACGGGCAGCGTCGAGACCTTGAGCAGCATCGAtccgctgttgctgcagaaGACCAGCTCGGTGGAGTATCATCAGCTGAAGCCGTTGGAGAACGGAGCCGGCGCCGGAACAACGGCGGCCGTGGTGAGCACATCCGGTTTTCTCGGCTCCACAACGGCCCAGCTGCTGGACTTCGAGGTggtgcccagcagcagcgacaaggATGCGATTGTGGCTGGCAACAATGGGCTGGCTGatacaacaactgcaactgcaacagcaacagcaactgcaacagcaacagcaacagctgcaacatcaACAAGCACTGCCAATCGAAGATCGCTGCACAGCATCGAGGAGCTGGCGGCAAGTTCCTGTGCTGCCgccaaaaccaacaacaatacaacacaacaacaacaacaacagcagcagcaacagcagcaacaacagcagcagcagcagcagcagcaacagcaacatcttcAACAGCAGACGGGCAATCTGAGCGGCTCCAACATAAGCTCCGAGGATGAGTCCATGTCGGAGGATGAATTTGGTCTAGAGATTGACGATCAAGGGGGGTATCAGGAAACGAACTCATCTCATTCACAGCAAAGCGGCAATGGAGCTGGCAACGCGGCGGCTGGCAACTCTGGCCAGCTGCTgaacggcagcagcggcgctgCGGGCAACGGTTatatgctgctgccgccgggcGCTGGCGGCGCCTCGGCTGCGCATATGTCCGGCAGCGTGGGCGGCAGCGGTGCGTCGGGCGGTGCGGGCGGCGCTGGTGGGGGTCATCATGGCGGCACGAGCGCCAGCTCTGGCGGCGGCGAGGCCATCGACTTTAAGCATCTGTTCGAAGAGCTGTGCCCCGTCTGCGGCGACAAGGTGAGCGGCTATCATTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTTCAAAACAAAAAGGTCTACACTTGCGTTGCGGAGCGCTCCTGCCACATCGATAAGACGCAGCGCAAACGTTGTCCCTATTGTCGATTCCAAAAGTGCCTGGAGGTGGGCATGAAACTAGAAGCGGTTCGAGCGGATCGCATGCGCGGCGGTCGGAACAAATTTGGACCCATGTACAAGCGGGATCGGGCGCGCAAGCTGCAGGTGATGCGTCAGCGGCAACTGGCGCTGCAGGCGCTGCGCAGTTCGATAGGCACGGACATAAAGCCGACGCCGCTGTCGCCGGGCTATCAGCAAGCATATccaaatatgaatattaagcAAGAAATTCAAATACCTCAGGTATCCTCACTCACGCAATCGCCGGACTCGTCGCCCAGCCCCATTGCGATCGCCTTGGGCCAGGTGAATGCAGGCGCGGGCGGTGTGATAGCCACGCCCCTGAATGCTGGCAATTTGagcggcggcaacggcaacggcggcagCTCTTCGCtgggcaatggcaacaacaacaccaacaacaacagcacaggcagcggcagcggcatcggCGGCGGGGGCGGGGGCAGTGGAGGAGGCAACAacgccggcggcggcagcggcagcggcggcggcggcggcggaggtgGCAGCAACAATCTCGCCGACGGCCTGCAACGCAACGGAAAcagtggcaacagcaacagcaacagcagttgcCACGAAACCGGACCTGGATCTCTGCAGAACACAGCCGAATCGAAATTGTGCTTTGATTCGGGCACACATCCATCGAGCACAGCCGATGCGCTCATCGAGCCACTGAGGGTCTCGCCGATGATACGTGAGTTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAGCTCTTTGCGCTGCTGCAGAAGCAGACGTACAACCAGGTGGAAGTGGATCTCTTTGAGCTAATGTGCAAAGTGCTGGATCAGAATCTGTTCTCGCAAGTGGACTGGGCACGAAACACTGTCTTCTTTAAGGACTTAAAGGTGGACGATCAGATGAAGCTGCTTCAGCACTCGTGGTCGGACATGCTTGTGCTGGATCATCTGCATCATCGCATACACAACGGCCTGCCGGACGAGACGCAGCTGAATAACGGTCAGGTCTTCAACCTGATGAGCCTCGGCCTGTTGGGTGTGCCACAGCTGGGCGACTACTTTAACGAGTTGCAAAATAAGCTGCAGGACCTGAAGTTCGATATGGGCGACTATGTGTGCATGAAATTCCTAATACTTTTAAATCCAGATGTGCGTGGAATCGTGAACAAAAAGACCGTCGTGGAGGGTCACGAGAATGTGCAGGCTGCGCTGCTGGATTATACACTGACGTGTTATCCCTCGGTTAATGACAAATTCAGGAGGCTGTTGAACATACTACCGGAAATTCACGCCATGGCCGCGCGGGGCGAGGAGCACCTGTACTCAAAGCACTGTGCCGGCAGTGCGCCCACGCAGACGCTGCTAATGGAGATGCTGCATGCCAAGCGGAAAGTGTAA
- Protein Sequence
- MDTFNVPLLAESSSSSSIANYAASNNNDSNNHHHQQHQHQNHHHHQHLQQQQQQQQQQQQQQLQQQQHQQPVLPHHHKDQMLAAGSTPMLPFINYAQLQKDALPNSNSNPPIENFSSLQAIDNSQLDGAVSLSGLCERIFASPNPHSNSNHNNNNNNNVDVKGSAPSSGGNGPLILESVSMSSFANILFNNNRSNNNNNNNSSQNTGSVETLSSIDPLLLQKTSSVEYHQLKPLENGAGAGTTAAVVSTSGFLGSTTAQLLDFEVVPSSSDKDAIVAGNNGLADTTTATATATATATATATAATSTSTANRRSLHSIEELAASSCAAAKTNNNTTQQQQQQQQQQQQQQQQQQQQQQQHLQQQTGNLSGSNISSEDESMSEDEFGLEIDDQGGYQETNSSHSQQSGNGAGNAAAGNSGQLLNGSSGAAGNGYMLLPPGAGGASAAHMSGSVGGSGASGGAGGAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNAGAGGVIATPLNAGNLSGGNGNGGSSSLGNGNNNTNNNSTGSGSGIGGGGGGSGGGNNAGGGSGSGGGGGGGGSNNLADGLQRNGNSGNSNSNSSCHETGPGSLQNTAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVVEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00519951;
- 90% Identity
- iTF_00563202;
- 80% Identity
- -