Dnov008503.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila novamexicana
Gene Symbol
ftz-f1
Assembly
GCA_003285875.3
Location
NW:2086345-2130422[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 2 1.3e+04 -5.5 13.2 64 104 30 70 10 112 0.50
2 5 2 1.3e+04 -13.1 18.3 165 207 298 341 121 354 0.63
3 5 2 1.3e+04 -9.4 16.9 41 87 325 369 274 396 0.50
4 5 2.3e-19 1.5e-15 57.1 0.5 1 79 554 631 554 652 0.75
5 5 4.1e-72 2.6e-68 230.8 1.1 157 408 763 1007 732 1009 0.91

Sequence Information

Coding Sequence
ATGGATACCTTTAATGTACCTTTGCTGgccgagagcagcagcagcagcattgccaaCTATgcggccagcaacaacaacgatagcaacaatcatcatcatcagcatcagcatcaccatcatcatcaccagcacctgcaacagcaacaacaacaacagcagcagcagcagcagcagcaacagcatcagccaGTGTTGCCACATCATCATAAGGATCAGATGCTCGCCGCGGGCAGCACACCAATGTTGCCATTCATTAACTATGCCCAGCTGCAGAAGGACGCGCTGCCCAACTCCAATTCCAATCCGCCCGTTGAGAGCTTTAGCTCATTGCAGGCCATCGACAACAGCCAATTGGATGGCGCCGTCTCCTTGAGCGGACTCTGCGAGCGCATCTTTGCCAGTCCCAATCCGCACAGTAATagcaatcacaacaacaacaacaacaatgtggaTGGCAAAGGGTCAGCGCCATCTAGCGGCGGCAACGGGCCGCTTATACTAGAATCCGTCTCCATGTCATCATTTGCCAACATTCTGTTCAACAACaatcgcagcaacaacaacagcgacagcaaccaGAACACGGCCAGCGTCGAGACACTCAGCAGCATCgatccgctgctgctgcagaagaCCAGCTCGGTCGAGTATCATCAGCTGAAGCCGTTGGAGaacggagccggagccggagcaaCGGCGGCCGTGGTGAGCACATCCGGTTTTCTCGGCTCCACAACGGCCCAGCTGCTGGACTTCGAGGTggtgcccagcagcagcgacaaggATGCGGTTGTGGCTGCCAACAACGGCCTGGCTGacacaacaactgcaactgcaacagcaacagcagcagcaactgcaactgcaacagctgcaacatcaACAAGCACTGCCAATCGAAGATCGCTGCACAGCATCGAGGAGCTGGCGGCTAGTTCCTGTGCTGCCgccaaaaccaacaacaatagcagcaacaatgcaacacaacaacaacaacaacagcagcagcaacaacaacagcaacagcaacatcttcaacaacaacaacaacaacagcaacagacgGGCAATCTCAGCGGCTCCAACATAAGCTCCGAGGATGAGTCTATGTCGGAGGATGAATTTGGCCTAGAGATTGACGATCAAGGGGGGTATCAGGAAACGAACTCATCTCATTCGCAGCAAAGCGGCAATGGAGCTGGCAACGCGGCGGCTGGCAACTCTGGCCAGCTGCTgaacggcggcagcggcgctgCGGGCAACGGTTatatgctgctgccgccgggcGCTGGCGGCGCCTCGGTTGCGCACATGTCCGGCAGCGTGGGCGGCAGCGGTGCGTCGGGCGGCGCTGGCGGTGCGAACGGCGCTGGTGGGGGGCATCATGGCGGGACGAGCGCCAGCTCTGGCGGCGGCGAGGCCATCGACTTTAAGCACCTGTTCGAGGAGCTGTGCCCCGTCTGCGGCGACAAGGTGAGCGGCTATCATTACGGCCTGCTCACGTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTTCAGAACAAAAAGGTCTACACTTGCGTTGCGGAGCGCTCCTGCCACATCGATAAGACGCAGCGCAAACGTTGTCCATATTGTCGATTCCAAAAGTGCCTGGAGGTGGGCATGAAACTAGAAGCGGTTCGAGCGGATCGCATGCGCGGCGGTCGGAACAAGTTTGGACCCATGTACAAGCGGGATCGGGCGCGCAAGCTGCAGGTGATGCGTCAGCGGCAACTGGCGCTGCAGGCGCTGCGCAGTTCGATAGGCACGGACATAAAGCCGACGCCGCTGTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcAGGAAATTCAAATACCTCAGGTATCCTCACTCACGCAATCGCCGGACTCGTCGCCCAGCCCCATTGCGATCGCCTTGGGCCAGGTGAATGCAGGCGCGGGCGGTGTGATAGCCACGCCCCTGAATGCTGGCAATTTGAGCGGCGGCAACGGGAACGGCGGCAGCTCCTCGCtgggcaatggcaacaacaacaccaacaacaacagcacaggcagcggcagcggcggcggcggcggcagtggAGGAGGCAACaacgccggcggcggcggcggcggaggtgGAGGTGGCAGCAACAATCTCGCCGACGGCCTGCAACGCAACGGAAAcagtggcaacagcaacagcaacagcagttgcCACGAAACCGGACCTGGATCTCTGCAGAACACAGCCGAATCGAAATTGTGCTTTGATTCTGGCACACATCCATCGAGCACAGCCGATGCGCTCATCGAGCCACTGAGGGTCTCGCCGATGATACGTGAGTTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAGCTCTTTGCGCTGCTGCAGAAGCAGACGTACAACCAGGTGGAAGTGGATCTCTTTGAGTTAATGTGCAAAGTGCTGGATCAGAATCTGTTCTCGCAAGTGGACTGGGCAAGAAACACCGTCTTCTTTAAGGACCTCAAGGTGGACGATCAGATGAAGCTGCTTCAGCACTCGTGGTCGGACATGCTCGTGCTGGATCATCTGCATCATCGCATACACAACGGCCTGCCGGACGAGACGCAGCTGAATAACGGGCAGGTCTTCAACCTGATGAGCCTCGGCCTGTTGGGTGTGCCACAGCTGGGCGACTACTTCAACGAGTTGCAAAATAAGCTGCAGGACCTGAAGTTCGATATGGGCGACTATGTGTGCATGAAATTCCTAATACTTTTAAATCCAGATGTGCGTGGAATCGTGAACAAGAAGACCGTCGTGGAGGGTCACGAGAATGTGCAGGCTGCGCTGCTGGATTATACACTGACGTGTTATCCCTCGGTTAATGACAAATTCAGGAGGCTTTTGAACATACTACCGGAAATTCACGCCATGGCCGCACGGGGCGAGGAGCACCTGTACTCAAAGCACTGTGCCGGCAGTGCGCCCACGCAGACGCTGCTTATGGAGATGCTGCATGCCAAGCGGAAAGTGTAA
Protein Sequence
MDTFNVPLLAESSSSSIANYAASNNNDSNNHHHQHQHHHHHHQHLQQQQQQQQQQQQQQQHQPVLPHHHKDQMLAAGSTPMLPFINYAQLQKDALPNSNSNPPVESFSSLQAIDNSQLDGAVSLSGLCERIFASPNPHSNSNHNNNNNNVDGKGSAPSSGGNGPLILESVSMSSFANILFNNNRSNNNSDSNQNTASVETLSSIDPLLLQKTSSVEYHQLKPLENGAGAGATAAVVSTSGFLGSTTAQLLDFEVVPSSSDKDAVVAANNGLADTTTATATATAAATATATAATSTSTANRRSLHSIEELAASSCAAAKTNNNSSNNATQQQQQQQQQQQQQQQHLQQQQQQQQQTGNLSGSNISSEDESMSEDEFGLEIDDQGGYQETNSSHSQQSGNGAGNAAAGNSGQLLNGGSGAAGNGYMLLPPGAGGASVAHMSGSVGGSGASGGAGGANGAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNAGAGGVIATPLNAGNLSGGNGNGGSSSLGNGNNNTNNNSTGSGSGGGGGSGGGNNAGGGGGGGGGGSNNLADGLQRNGNSGNSNSNSSCHETGPGSLQNTAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVVEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00519951;
90% Identity
iTF_00616932;
80% Identity
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