Basic Information

Insect: Drosophila hydei
Gene Symbol: ftz-f1
Assembly: GCA_003285905.2
Location: NW:15527650-15566652[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.54 3.5e+03 -3.4 0.8 64 97 27 60 14 92 0.55

2 5 2 1.3e+04 -11.4 16.9 65 200 174 333 141 345 0.43

3 5 2 1.3e+04 -6.6 10.6 35 83 298 346 263 374 0.51

4 5 1.4e-19 9.2e-16 57.8 0.1 1 80 536 614 536 663 0.78

5 5 2e-72 1.3e-68 231.8 0.7 154 408 734 981 704 983 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.54	3.5e+03	-3.4	0.8	64	97	27	60	14	92	0.55
2	5	2	1.3e+04	-11.4	16.9	65	200	174	333	141	345	0.43
3	5	2	1.3e+04	-6.6	10.6	35	83	298	346	263	374	0.51
4	5	1.4e-19	9.2e-16	57.8	0.1	1	80	536	614	536	663	0.78
5	5	2e-72	1.3e-68	231.8	0.7	154	408	734	981	704	983	0.92

Sequence Information

Coding Sequence: ATGGAAAATTTTAATGTACCTTTGCTGGCCGagagcagcaccagcagttTCGTTAACAATGCAGCCAGCGGCAATAACGATAGCAACAACCAACATCACCAGCatctgcaacaacagcaacaattactTCCTCATCATCACAAGGATCAAATGTTAGCCGCTGGCAGCACTTTTTTGCCCTTTATCAACTATACGCAGCTGCAGAAGAACACTCAGTCCAATTCTGATTCCAATCCGCCGGTGGAAAACTTTAGCTCATTGCACGCCATCGACGGCAACCAATTGGATGTTGCTGTCTCTTTGGGAGGACTATGCGATCGCATATTTCCCAGTCCCAATCCGcacagcaccaacaacaacaaccacgtCGATGTTAAATTGTCAGCGCCATCTGGCGGTAACAGTGGGCCAGTCATATTAGAATCAGTCACAATGTCATCATTTGCCAATATACTGTTCAACAAccgcaataataataacaacaataataataccaacaatagtaataataatagcaacaataataataataacaacaacaaccagcttACGGCTAGCATCGAAACGCTCAATAGCATTGACCCACTGCTACTCCAAAAGTCAAACTCAGTGGAGTATCATCAGCTAAAGCCATTGAAGAACGGAGCAGTCTCAACGCCGGTTGTGAGCACATCTGGATTTTTAAACTCCACAACAGCACAGCTGTTAGACTTTGAGGTGGTTCCGAACAATAACAATAGAGATGCGATAGTCGCAGGCAGCAATGGATTGGccgacacaacaacaacaacaacaacaacggcagcagcagcaacatcagcatgTACAGTCAATCGAAGATCGCTGCATAGCATTGAGGAGCTGGCGGCCAGTTCCTGCGCCGCAACTAATGTCAACACCACAACCATTATAACACAGGTGGAACAGCAAAAGGAGCAACACAAAGAAcatcaacaccaacagcaacatcatcagcaccatcaacaacaacagcagcaacatcaagcAGGAAATCTCAGTGGATCCAACATTAGCTCCGACGATGAGTCCATCTCAGAGGATGAATTTGGTCTTGAGATCGATGATCAGGGAGGCTATCAGGAAACCAACTCGTCACATTCGCAGCAAAGCGGCAACGGCGCTGGTGTAGCATCTGCTAACTCTGGCCAGCTACTAAAcggtggcagcaacagctctgcCGGCAACGGTTATATGTTGCTGCCACCAGGTGGCGCTTCAGCTGCTCACATGTCCGGCAATGTGGCTGGCAGCGGAGCAGCTGGTGGAGCGGGCAATGTCGCGTCGGCTGGAGTTGTTGGCGGTGGTCACCATAGTGGAACAAGCGCCACCTCTGGCGGTGGCGAAGCCATCGACTTCAAGCACTTGTTCGAGGAGCTGTGCCCTGTTTGTGGGGATAAGGTGAGCGGCTACCACTACGGCCTGCTCACCTGTGAATCCTGCAAGGGCTTCTTCAAGCGGACCGTTCAGAACAAAAAGGTCTACACATGCGTTGCGGAACGCTCCTGCCACATTGATAAAACGCAGCGCAAACGTTGTCCATATTGCCGATTCCAAAAGTGCCTCGAAGTGGGCATGAAACTTGAGGCGGTTCGAGCAGATCGTATGCGTGGAGGCCGTAACAAATTTGGACCCATGTACAAAAGGGATCGGGCGCGCAAGCTGCAGGTGATGCGACAGCGGCAGCTTGCCCTGCAGGCGCTGCGGAGTTCTATAGGTTCAGATATAAAGCCAACACCTCTCTCGCCTGGCTATCAGCAAGCATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGGTATCCTCACTTACGCAATCGCCGGATTCGTCACCCAGCcccattgccattgctttGGGTCAGGTGAATGCTGGCGCTGGCGGTGTGATAGCCACCCCCCTGAATGTTGGCAATTTAAGTGGCGGCAGCTCGCTAGGCAATGGGAGCAGcaacaccaccaacaacaacagcacaggAAGCAGTGGTGGCGGCGGGGGTAGTGGGGGTGGAAATAACGCTGGCGGGGGAAGCggtgccaacaacagcaataacattCCCGATGGCCTGCAACGTAACGGAAACAgtggcaatagcaacagcaacagcagctgccatgaAACCGGGAATGGATCTCTGCAGAACACAGCTGACTCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGGAGACGCGGTCATTGAGCCACTGAGgGTCTCGCCGATGATACGAGAGTTTGTGCAATCGATCGATGATCGGGAATGGCAGACTCAGCTTTTTGCGCTGCTGCAGAAGCAGACCTATAACCAAGTTGAAGTTGATCTCTTTGAGCTAATGTGCAAAGTGCTGGATCAAAATCTGTTCTCACAAGTGGATTGGGCAAGAAACACTGTCTTTTTTAAGGATTTAAAGGTGGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCGGACATGCTTGTGTTGGATCATCTGCATCATCGTATACACAACGGTTTGCCGGATGAGACGCAGCTGAATAACGGGCAGGTGTTTAACCTAATGAGCCTTGGCCTATTGGGAGTGCCACAGTTGGGAGACTACTTTAACGAGTTGCAAAATAAGCTGCAGGACCTGAAGTTCGATATGGGAGACTATGTGTGCATGAAATTCCTAATACTTTTAAATCCAGATGTACGTGGAATAGTGAACAAAAAGACCGTTGTGGAGGGACACGAGAATGTTCAGGCAGCTTTGCTGGATTATACACTTACATGTTACCCCTCAGTAAATGACAAATTTAGGAGGCTTTTGAATATACTACCGGAAATTCACGCCATGGCCGCTCGCGGCGAAGAACATCTATACTCAAAGCATTGTGCTGGCAGTGCACCCACGCAGACGCTGCTCATGGAGATGCTGCATGCTAAACGAAAGGTGTGA
Protein Sequence: MENFNVPLLAESSTSSFVNNAASGNNDSNNQHHQHLQQQQQLLPHHHKDQMLAAGSTFLPFINYTQLQKNTQSNSDSNPPVENFSSLHAIDGNQLDVAVSLGGLCDRIFPSPNPHSTNNNNHVDVKLSAPSGGNSGPVILESVTMSSFANILFNNRNNNNNNNNTNNSNNNSNNNNNNNNNQLTASIETLNSIDPLLLQKSNSVEYHQLKPLKNGAVSTPVVSTSGFLNSTTAQLLDFEVVPNNNNRDAIVAGSNGLADTTTTTTTTAAAATSACTVNRRSLHSIEELAASSCAATNVNTTTIITQVEQQKEQHKEHQHQQQHHQHHQQQQQQHQAGNLSGSNISSDDESISEDEFGLEIDDQGGYQETNSSHSQQSGNGAGVASANSGQLLNGGSNSSAGNGYMLLPPGGASAAHMSGNVAGSGAAGGAGNVASAGVVGGGHHSGTSATSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGSDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNAGAGGVIATPLNVGNLSGGSSLGNGSSNTTNNNSTGSSGGGGGSGGGNNAGGGSGANNSNNIPDGLQRNGNSGNSNSNSSCHETGNGSLQNTADSKLCFDSGTHPSSTGDAVIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVVEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519971; iTF_00563202; iTF_00616932;
90% Identity: iTF_00519971;
80% Identity: iTF_00519971;