Dtro009510.1
Basic Information
- Insect
- Drosophila tropicalis
- Gene Symbol
- lrrfip2
- Assembly
- GCA_018151085.1
- Location
- JAECWH010000837.1:596471-601893[+]
Transcription Factor Domain
- TF Family
- LRRFIP
- Domain
- LRRFIP domain
- PFAM
- PF09738
- TF Group
- Unclassified Structure
- Description
- LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.2e-124 4.1e-120 400.7 26.7 1 299 102 393 102 394 0.99 2 2 0.098 1.8e+03 -2.0 3.2 135 151 428 444 397 468 0.43
Sequence Information
- Coding Sequence
- ATGGATAGTACAAGCGCCACCGGTCGACGGCGAAACAATACGCGAGTCAATGCCGAGGATAATGCTCTAGATCAAATCACAAAGGAGGCAACAATGGAAGCGATCGAGTTGGACGATCAAATAATAAATAATAAAGAAGATCGTACGACGATCATGCCACCTACACCTACCACCACAGAACCTTGTCTAATTGACGACGGCGACAGTGATGATCATGATGATGAGAAACTGTCTGGCGGCGACGACGAGAGTGAGTCCGAAGAGGAAGTGTTAGTGCAATTCTTGGGCGAGGCAAATCGCATTGCCGAAGCTCGTTTAGCAGCGCGGCGTCAAGCTCGTGCAGAGGCACGGGAAATTCGTATGCGGGAGCTAGAGCGCCAGCAGAAGGAGCAAGAACAAAATGCCGATCGCGTCTTTGACATGCAAAACACCAGCGGTGCCGGTGGAGACACAATTTCCACCCATCCTGCGCGTCTTGTGTATGGCGGTGGCCTCCTGAATGTTACCCGTGCCACAGCATCGCGTCGCAGTAGCGAGGATTCATTGGAAGATGAAAGCCGAAGTTTACGTGACATGAAACATGAGCTCAAAGACGTTGAAGAACGCTTCCGAAAAGCAATGATAACGAATGCTCAGCTAGACAATGATCGTGCCTCACAAACATACGAAGTCAAGCTACTCAAGGACAGAAGCGAAACCATGCAAGAGTCATTGGCTCAATTGCAACGCGAGTACAAGGAGAAAATGCGTGAATACAATGCATTGAAACGTAACTTGGATCGCACCACTTTGGAGCTACAACTGGTACAGGGCCAGTTGAATGAGCGCGATTCTTTGATAGCAGAACAGGGTCTTGTGATTGTAGCTATTGAGAACTCCGATGGCAGTGATGCCAAGCGGGCTCTAGTCAGTGTTGATAACGCCAATGTCTTAGCCTCCGTGCAGGGTTCGTTAGATGTAAGACTTAAAAAATTTAGCGAAGATAAACAGCTGCTTCTTGCGGAGGTACAGAAGCTCAATGAACAACTGGAAGAGTATAAAAGTGACGGCAAAATAGGCCACGGCAGTTCATCGTACGGAACATTCGGCTATGACGATGATTATGAGGCTCAGAGAGAAGCAAATAAAATAATTTCGGATTATAAGTATAAACTGCAAAAGGCTGAACAAGAAATTGCAAGTCTGCAGGCGAGCTTAGCACGTTCAGAAACTCAGGTTATACGATACAAGAGCACGGCGGAAGCAGCTGAAAAAGCGGAGGCCGAATTGAAAGTGGAGCGGCGTAAGCTCCAACGTGAGAACCGTGAAAATTTAGAGCGATTGGAAGAAGCGGAAACAGCAAATAATCATTTACTAAAACGGCTTGATAAATTAAAAAACGCAAAGAGTGCAATCCTGAAGGACTTATGA
- Protein Sequence
- MDSTSATGRRRNNTRVNAEDNALDQITKEATMEAIELDDQIINNKEDRTTIMPPTPTTTEPCLIDDGDSDDHDDEKLSGGDDESESEEEVLVQFLGEANRIAEARLAARRQARAEAREIRMRELERQQKEQEQNADRVFDMQNTSGAGGDTISTHPARLVYGGGLLNVTRATASRRSSEDSLEDESRSLRDMKHELKDVEERFRKAMITNAQLDNDRASQTYEVKLLKDRSETMQESLAQLQREYKEKMREYNALKRNLDRTTLELQLVQGQLNERDSLIAEQGLVIVAIENSDGSDAKRALVSVDNANVLASVQGSLDVRLKKFSEDKQLLLAEVQKLNEQLEEYKSDGKIGHGSSSYGTFGYDDDYEAQREANKIISDYKYKLQKAEQEIASLQASLARSETQVIRYKSTAEAAEKAEAELKVERRKLQRENRENLERLEEAETANNHLLKRLDKLKNAKSAILKDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00600311;
- 90% Identity
- iTF_00618406; iTF_00523691; iTF_00503264; iTF_00483683; iTF_00571152;
- 80% Identity
- -