Basic Information

Insect: Drosophila tristis
Gene Symbol: -
Assembly: GCA_018150885.1
Location: JAECWT010000189.1:622984-627401[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 7.2e-05 0.0048 17.0 0.1 1 23 160 183 160 183 0.96

2 13 0.0015 0.1 12.9 3.1 2 23 232 254 228 254 0.90

3 13 0.0066 0.44 10.9 0.8 1 23 343 366 343 366 0.93

4 13 0.29 19 5.7 5.4 2 23 415 437 414 438 0.95

5 13 0.0012 0.082 13.2 0.6 1 23 501 524 501 524 0.88

6 13 0.0006 0.04 14.1 3.3 2 23 575 597 575 597 0.96

7 13 0.00048 0.032 14.4 0.0 1 23 682 705 682 705 0.95

8 13 0.0006 0.04 14.1 0.2 1 23 766 789 766 789 0.93

9 13 0.001 0.067 13.4 2.2 2 23 839 861 838 861 0.97

10 13 0.0029 0.19 12.0 3.8 1 23 954 976 954 977 0.94

11 13 0.046 3.1 8.2 1.5 1 21 1029 1049 1029 1050 0.95

12 13 0.34 23 5.5 0.0 2 23 1091 1115 1090 1115 0.81

13 13 0.94 63 4.1 0.6 1 23 1132 1156 1132 1156 0.73

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	7.2e-05	0.0048	17.0	0.1	1	23	160	183	160	183	0.96
2	13	0.0015	0.1	12.9	3.1	2	23	232	254	228	254	0.90
3	13	0.0066	0.44	10.9	0.8	1	23	343	366	343	366	0.93
4	13	0.29	19	5.7	5.4	2	23	415	437	414	438	0.95
5	13	0.0012	0.082	13.2	0.6	1	23	501	524	501	524	0.88
6	13	0.0006	0.04	14.1	3.3	2	23	575	597	575	597	0.96
7	13	0.00048	0.032	14.4	0.0	1	23	682	705	682	705	0.95
8	13	0.0006	0.04	14.1	0.2	1	23	766	789	766	789	0.93
9	13	0.001	0.067	13.4	2.2	2	23	839	861	838	861	0.97
10	13	0.0029	0.19	12.0	3.8	1	23	954	976	954	977	0.94
11	13	0.046	3.1	8.2	1.5	1	21	1029	1049	1029	1050	0.95
12	13	0.34	23	5.5	0.0	2	23	1091	1115	1090	1115	0.81
13	13	0.94	63	4.1	0.6	1	23	1132	1156	1132	1156	0.73

Sequence Information

Coding Sequence: ATGGAAGGAATGGACCTTTGGACATCCATGTTCTCGGCAGACTTTGAGGAGGGCGAGGAGGAGATCGAGCAATATGCGAACGAAAACGGCCTGGACAGCAATCCTGTCGGCGACGGTGATGACATTCTGCCCGAGGATGATGATAATGATGCGGAAGACGCTGTGGATGAGGAGGAGGAGGAGGCAACTGGCCGTGGGAATGGAAAAACAAAAGAGCCCGATTTAGATGATGATGCCATATTTGATTTCGATCTGGAGCCGATTGTAAGTATTGGCGAGCCACAGCCCCCTCCAGTGCCGGCGCCTACTGGTCCACTTGGCTCACCTGTGCGTCCCATGCTTCGCCACTCACTGCCCGCCAGGCAGGGCCGGCCCAAGGAGGTGTGTCCGACGGGAGGGCTCACGCGGCCCACCACCTCGCAGATCAATGCAACCGATGCGAACGGGATCCCCATAAACTATGAGCTGGGCGTCATCTACATCTGCCCCGCATGCGGAGCAGAATTCCGGCAGCAGGATCTCTGGAAGCGCCACATGAACCAAATGCACCAGTTCAACACGCGGCGTGGCCTCAACTTCATGGCCATGGACAAGCTCTATCATCGGTGCCTGGAGTGCAACAAGCGCATCGCCATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACCCACTTGCCGTTTAGGTGCACCAAGTGCTACATCTGCAAGCGGGAGTACAAATACAGACAAGACCTGATGGTTCACCTGAGGATGGTCCATTGCGACGAAGTGGTGGCCATGATGCGGGAGGGCTTCAACTTGGCGGGACGCAAGACGCGGGTACGGGAGCCGCGCACAGAGCAAATGCAGCGCAAGGATCCTTTCCCAGAGGAGGACAACGAGCAAAACGATCTTCTCGAGCCGGAGACTGAGACTATGCCACCCATGCTGGAGGAGGAAGCTCCGCAGAGGCGTCGGAAAAAGCGCTACCAAGGAGGTCCCTCTGGCGACGGAGGGGCGGATCTTTGCGAGGATTACATCCACTACATGTGCCCCGATTGCGGCACTGAGTGCGACACCCACGCACAGTGGAGTCAACACATTGAATTCGTCCACGACTACGTCAGCCGCAGGGGTCTCAACTTCATCAGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTCATCCCCAACACCATTAAGACGCTGCGCGCCCACAAGTTCACGCATTTGCCGCAGCCCGAGTGGCTGCGCTGCAAGCTGTGCTATAAGGGCTACACGGAACACCACGAGCTGGTCAGCCATCTGCTGAAGCAACACCACCTGGAGACGCTGATGCCAGAGGAGTCGCCGGATCCATCACCCGTCAAAAGGACAGATGGCGGAGGCGACGACTGGGAGGACAATGTGAACGGCAGCGCCTTTGATGACGTTTCGCCGCAATTTGAGGATGTACCCCGACGGGGAGGGCGTATCGGGAGCGATGACATGTACGAGCCACACATCGACTACCTGTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCATGTGGTGCAGGTGCACGGCATGAACGATGTGACCAAGCTCAACTTTGCGATAATCAACGATCGCCAGCTGAAGTGCACGGAGTGCGCCAAAATCATAACGAACGCCTACGGCATACAGAATGCCCAGCAGCACAGGATCACGCACCTTCCATTCAAGGCGTACGCCAGGTGCCGCAAGTGCCACAAGTCCTACACAGATCGCAAGGGTCTGGTCAAGCACCTGGCCACCTACCATCGTGTAGGCTACGTTCCGCACAAAAATTTCAGAATGGCCGGACGAGGAGCCCGGCAGTTTGTGTCACCCAAGCAGCAGCGCAAACAGATTGTGACCCTGGGAAAGGAGACCTACGAGATAATCTTCCTTGATGAAGAGCAGGCGCACTCGAGTGTCGACGAGGAGAACGACTTTGGGGAGCAGATGCAGATGGCGGACGAGGAGGACGTGCCCACTGTCAGTACCGACTTGCCGCCGCCCAATCCGAATCGCTACAAGTGCGTAGAATGCGGAACCTTGTTCCCCACGCAAGTAGCTCTCAAGCTGCACATCAGCGAGGCACATACACATGCGTTGCGGGATCCCCCTCAGTACGGGGGATCGAAGAAGTTGGACACATCCCAGGGCAAAGAGGAGGCGTCCAAGAAGAGGAGATTGGGAGCGGGACCAGCAGCAGCATTAATACCCTTAGCAACAGCGGCCACAAGTAGCCCATCGGCGGGCACGGTAGAGCAGAACTACATTTTCCTGTGCCCCTCGTGCGGCGAGGAGTACAAGACACAGTTCGAGTGGCGCCGTCACATCAACGAGGCGCACAACTTCGACAAACGGCAGTATCTGAATATGCGGCAGCTGGACAAGTACCGCTACCAGTGCACCCAGTGCAACGACATTGTGTGCAACTCCAAGCTGAAGGGCCTGCAGGACCACCATTTCCGGCATCTGCCCTTCCGCCTGTACCTCAAGTGCCTCGTGTGCGGCACCTGCTACAACCACAAGCCCAACATTGCCGCCCATCTGAGGACGCGGCACAACATCTACGAGCGGGAAACGCCATGGCGGGAGCTGCAAACCAAGCCCCAGTACTCGTATGTCCAGTCCAAGGAGAAGGACAGGGGTACGGTCGCCAAGAGCAGGCCACAATCACCCCCGCCCGCAGTTGTCGCCTCGTCCTCAGGCTCCAGCGCCAGCGCCAGCAGTCGCCCGCTCTGGCCGCAGTCCGAGAAGCGTCCCACTCGGCCGGCCGGACTCAACACCCTGGAGGACAGCATCTCGTACCACAATGCGGTGGACATGGACTTCATCACCTACTACTGCCCCAAGTGCAACAAGAATTTCGACTCTCATGCCTTCTGGCGCAAGCACATCGTGGAGCATCACAACTTCAACAGTCGCGAGGGCCTAAACTTCCGCCAGATTGACATGCACCACTACTTGTGCCTGGAGTGCTACAAGCGTGTCACCGTCACTCACACCAAGGGCGCCATCGGGCAGCTCCAGTCGCACAAGTTCCGCCACCTGCCGTACCGCTCCTTCAAGTGTCTCACCTGCAACGGAGAGTTTGTGCGCAAGCAGATGTTCTTCAAGCATCTTAATCGGGACACCAATCGGTGCGACAACAAGCCCAGCGCCGAAAAGGTGTTTGATGACGAGGAGCAGGAAACGGGTGGCGTGGCCTCCGCAGAAGATGAAGACGCAGAAGCATCAGCCTATCGGCTAATGTGCCCCCAGTGCGGCGACGACTTTACCACCAGCAGCCAAGCGGCGTGGCGCAACCACCTTAACGTCGCCCACGGCCTGGGCAAGCAGCCTCTGCACATTCGGAAGGTGGGCGAGGGGCTCTACCGCTGCTACGACTGCGACGAGGAGTTGGCGACGAAGAGCAAGGGTGTCCTGCAGCAGCACCGCTTCAAGCATATGCCCCATGCCGCCTACATTCTTTGCCAACTTTGCGAGAGCGGGCCGGATGAGAAGACGGCTGAAGTGCACAGCATGCAGGAGCTGCATCAGCACATCCGCGAGCACCATCCTGCCGTGGAAGAGAGCGACGAGAGGCTGCAGAAGGTGCGCCAACTCATAGACGAGGAGGGGACCGACGAGGACAGCGAGACACCAGCCAACAGCGACAATGGAGCTGGCTCGACGGCGAACAATGGTCCGTACATGCCGCTACCGCCGCATTTACTGGACGAGGATGATGATTTGGATTTTGAGGATCAATATCTGCTGGGATAG
Protein Sequence: MEGMDLWTSMFSADFEEGEEEIEQYANENGLDSNPVGDGDDILPEDDDNDAEDAVDEEEEEATGRGNGKTKEPDLDDDAIFDFDLEPIVSIGEPQPPPVPAPTGPLGSPVRPMLRHSLPARQGRPKEVCPTGGLTRPTTSQINATDANGIPINYELGVIYICPACGAEFRQQDLWKRHMNQMHQFNTRRGLNFMAMDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGFNLAGRKTRVREPRTEQMQRKDPFPEEDNEQNDLLEPETETMPPMLEEEAPQRRRKKRYQGGPSGDGGADLCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFISVDMQMQCLECKKIVIPNTIKTLRAHKFTHLPQPEWLRCKLCYKGYTEHHELVSHLLKQHHLETLMPEESPDPSPVKRTDGGGDDWEDNVNGSAFDDVSPQFEDVPRRGGRIGSDDMYEPHIDYLCPQCGKEFIEKKHWRTHVVQVHGMNDVTKLNFAIINDRQLKCTECAKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGYVPHKNFRMAGRGARQFVSPKQQRKQIVTLGKETYEIIFLDEEQAHSSVDEENDFGEQMQMADEEDVPTVSTDLPPPNPNRYKCVECGTLFPTQVALKLHISEAHTHALRDPPQYGGSKKLDTSQGKEEASKKRRLGAGPAAALIPLATAATSSPSAGTVEQNYIFLCPSCGEEYKTQFEWRRHINEAHNFDKRQYLNMRQLDKYRYQCTQCNDIVCNSKLKGLQDHHFRHLPFRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERETPWRELQTKPQYSYVQSKEKDRGTVAKSRPQSPPPAVVASSSGSSASASSRPLWPQSEKRPTRPAGLNTLEDSISYHNAVDMDFITYYCPKCNKNFDSHAFWRKHIVEHHNFNSREGLNFRQIDMHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPSAEKVFDDEEQETGGVASAEDEDAEASAYRLMCPQCGDDFTTSSQAAWRNHLNVAHGLGKQPLHIRKVGEGLYRCYDCDEELATKSKGVLQQHRFKHMPHAAYILCQLCESGPDEKTAEVHSMQELHQHIREHHPAVEESDERLQKVRQLIDEEGTDEDSETPANSDNGAGSTANNGPYMPLPPHLLDEDDDLDFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603660;
90% Identity: iTF_00474795; iTF_00564235;
80% Identity: -