Basic Information

Insect: Drosophila ambigua
Gene Symbol: -
Assembly: GCA_018150905.1
Location: JAECWS010000100.1:8333933-8337853[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 7.2e-05 0.0048 17.0 0.1 1 23 161 184 161 184 0.96

2 13 0.0015 0.1 12.9 3.1 2 23 233 255 229 255 0.90

3 13 0.0066 0.44 10.9 0.8 1 23 344 367 344 367 0.93

4 13 0.2 14 6.2 5.4 2 23 416 438 415 439 0.95

5 13 0.0012 0.082 13.2 0.6 1 23 502 525 502 525 0.88

6 13 0.0006 0.041 14.1 3.3 2 23 576 598 576 598 0.96

7 13 0.00048 0.033 14.4 0.0 1 23 683 706 683 706 0.95

8 13 0.0006 0.041 14.1 0.2 1 23 767 790 767 790 0.93

9 13 0.001 0.068 13.4 2.2 2 23 840 862 839 862 0.97

10 13 0.0028 0.19 12.0 3.8 1 23 955 977 955 978 0.94

11 13 0.046 3.1 8.2 1.5 1 21 1030 1050 1030 1051 0.95

12 13 0.31 21 5.6 0.1 2 23 1092 1116 1091 1116 0.76

13 13 0.94 63 4.1 0.6 1 23 1133 1157 1133 1157 0.73

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	7.2e-05	0.0048	17.0	0.1	1	23	161	184	161	184	0.96
2	13	0.0015	0.1	12.9	3.1	2	23	233	255	229	255	0.90
3	13	0.0066	0.44	10.9	0.8	1	23	344	367	344	367	0.93
4	13	0.2	14	6.2	5.4	2	23	416	438	415	439	0.95
5	13	0.0012	0.082	13.2	0.6	1	23	502	525	502	525	0.88
6	13	0.0006	0.041	14.1	3.3	2	23	576	598	576	598	0.96
7	13	0.00048	0.033	14.4	0.0	1	23	683	706	683	706	0.95
8	13	0.0006	0.041	14.1	0.2	1	23	767	790	767	790	0.93
9	13	0.001	0.068	13.4	2.2	2	23	840	862	839	862	0.97
10	13	0.0028	0.19	12.0	3.8	1	23	955	977	955	978	0.94
11	13	0.046	3.1	8.2	1.5	1	21	1030	1050	1030	1051	0.95
12	13	0.31	21	5.6	0.1	2	23	1092	1116	1091	1116	0.76
13	13	0.94	63	4.1	0.6	1	23	1133	1157	1133	1157	0.73

Sequence Information

Coding Sequence: ATGGAAGGAATGGACCTTTGGACATCCATGTTCTCGGCAGACTTCGAGGAGGGCGAGGAGGAGATCGAGCAATATGCAAATGAAAACGGCGTGGACAGCAATCCTGCCGGCGACGGGGATGACATTCTGCCCGAGGATGATGAAAATGATGCGGAAGACGCTGCGGAAGAGGAGGAGGAGGAGGCAACTGGCCGTGGCAATGGCAAAACAAAAGAGCCCGATTTAGATGATGATGATGCCATATTTGATTTCGATCTGGAGCCGATTGTAAGTATTGGCGAGCCACAGCCCCCTCCAGTGCTGGCGCCTACTGGTCCACTTGGCTCACCTGTGCGTCCCATGCTTCGCCACTCACTGCCCGCCAGGCAGGGCCGGCCTAAGGAGGTGTGTCCGACGGGAGGGCTCACGCGGCCCACCACCTCGCAGATCAATGCAACCGATGCGAACGGGATCCCCATCAACTATGAGCTGGGCGTCATCTACATCTGCCCCGCATGCGGAGCAGAATTCCGGCAGCAGGATCTCTGGAAGCGCCACATGAACCAAATGCACCAGTTCAACACGCGGCGTGGCCTTAACTTCATGGCCATGGACAAGCTCTATCATCGGTGCCTGGAGTGCAACAAGCGCATCGCCATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACCCACTTGCCGTTCAGGTGCACCAAATGCTACATCTGCAAGCGGGAGTACAAATACAGACAAGACCTGATGGTTCACCTGAGGATGGTCCATTGCGACGAAGTGGTGGCCATGATGCGGGAGGGCTTCAACTTGGCGGGACGCAAGACGCGGGTGCGGGAGCCGCGCACAGAGCAAATGCAGCGCAAGGATCCGTTCCCAGAGGAGGACAGTGAGCAGAACGATGTTCTCGAGCCGGAGACTGAGACCATGCCACCCATGCTGGAGGAGGAAGCTCCGCAGAGGCGCCGGAAAAAGCGCTACCAAGGAGGTCCCTCTGGCGACGGAGGGGCGGATCTTTGCGAGGATTACATCCACTACATGTGCCCCGATTGCGGCACTGAGTGCGACACCCACGCCCAGTGGAGTCAGCACATTGAATTTGTCCACGACTACGTCAGCCGCAGGGGTCTCAACTTCATCAGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTCATCCCCAACACCATTAAGACGCTGCGGGCCCACAAGTTCACGCATCTGCCGCAGCCCGAGTGGCTGCGCTGCAAGCTGTGCTACAAGGGCTACACGGAACACCACGAGCTGGTCAACCATCTGCTGAAGCAACACCACCTGGAGACGCTGATGCCAGAGGAGTCGCCGGATCCATCGCCCGTCAAAAGGACAGATGGCGGAGGCGACGACTGGGAGGACAATGTAAACGGCAGCGTCTTCGATGACGTTTCGCCGCACTTTGAGGATGTACCCCGACGGGGAGGGCGCATCGGAAGCGATGACATGTACGAGCCACACATCGACTACCTGTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCATGTGGTGCAGGTGCACGGCATGAACGATGTGACAAAGCTCAACTTTGCGGTAATCAACGATCGCCAGCTGAAGTGCACGGAGTGCGCCAAAATCATAACGAACGCCTACGGCATACAGAATGCCCAGCAGCACAGGATCACGCACCTTCCATTCAAGGCATACGCCCGGTGTCGCAAGTGCCACAAGTCCTACACAGATCGCAAGGGTCTGGTCAAGCACCTGGCCACCTACCATCGTGTGGGCTACGTTCCGCACAAAAATTTCAGAATGGCCGGACGAGGAGCCCGGCTGTTGGGGGCGCCCAAGCAGCAGCGCAAGCAGATTGTGACCCTGGGAAAAGAGACCTACGAGATAATCTTCCTCGATGAAGAGCAGACGCACTCGAGTGTCGACGAGGAGAACGACTTTGGCGAGCAGATGCAGATGGCGGACGAGGAGGATCTGCCCACTGTCAGTACCGACTTGCCGCCGCCCAATCCGAATCGCTACAAGTGCGTAGAATGCGGAACATTGTTCCCCACGCAAGTGGCTCTCAAGTTGCACATCAGTGAGGCACATACACATGCGTTGCGGGATCCGCCTCAGTACGGGGGATCGAAGAAGTTGGACCCATCCCAGGGCAAAGAGGAGGCATCCAAGAAGAGGAGATTGGGAGCGGGACCAGCAGCAGCGTTAATACCAGCAGCAGCAGCGGCCACAAGTAGCCCATCGGCGGGCACGGTAGAGCAGAACTACATATTCCTGTGCCCCTCGTGCGGCGAGGAGTACAAGACACAGTTCGAGTGGCGCCGTCACATCAACGAGGCGCACAACTTCGACAAACGGCAGTATCTGAATATGCGGCAGCTGGACAAGTACCGCTACCAGTGCACCCAGTGCAACGACGTTGTGTGCAACTCCAAGCTGAAGGGCCTGCAGGACCACCATTTCCGACATCTGCCCTTCCGCCTGTACCTCAAGTGCCTCGTGTGCGGCACCTGCTACAACCACAAGCCCAACATTGCCGCCCATCTGCGGACGCGGCACAACATCTACGAGCGGGAAACGCCATGGCGGGAGCTGCAAACCAAGCCCCAGTACTCGTATGTTCAGTCCAAGGAGAAGGACAGGGGTACGGTCGCCAAGAGCAGGCCACAATCACCCTCACCCGCAGTTGTCGCCTCGTCCTCAGGCTCCAGCGCCAGCGCTAGCAGTCGCCCGCTCTGGCCGCAGTCCGAGAAGCGTCCCACTCGGCCGGCCGGACTCAACACGCTGGAGGACAGCATCTCATACCACAATGCGGTGGACATGGACTTCATCACCTACTACTGCCCCAAGTGCAACAAGAATTTCGACTCTCATGCCTTCTGGCGCAAGCACATCGTGGAGCACCACAACTTCAACAGTCGCGAGGGCCTAAACTTCCGGCAGATTGACATGCACCACTACTTGTGCCTGGAGTGCTACAAGCGTGTCACCGTCACACACACCAAGGGCGCCATCGGGCAGCTGCAGTCGCACAAGTTCCGCCACCTGCCGTACCGCTCCTTCAAGTGTCTCACCTGCAACGGAGAGTTTGTGCGCAAGCAGATGTTCTTCAAGCATCTTAATCGGGACACCAATCGGTGCGACAACAAGCCCAGCGCCGAAAAGGTGTTTGATGACGAGGAGCAGGAAACGGGTGGCGTGGCCTCCGCAGAAGATGAAGACGCAGAAGCATCAGCCTATCGGCTAATGTGCCCCCAGTGCGGCGACGAATTCACCACCAGCAGCCAGGCGGCATGGCGCAACCACCTTAACGTCTCCCACGGCCTGGGCAAGCAGCCTCTGCATATTCGGAAGGTGGGCGAGGGCCTCTACCGCTGCTACGACTGCGACGAGGAGCTGGCGACGAAGAGCAAGGGTGTCCTGCAGCAGCACCGCTTCAAGCACATGCCCCATGCCGCCTACATTCTTTGCCAACTTTGCGCGAGCGGGACGGATGAGAAGGCGGCTGAAGTGCACAGCATGCAGGAGCTGCATCATCACATCCGCGAGCACCATCCTGCAGTGGAGGAGAGCGACGAGAGGCTGCAGAAGGTGCGCCAACTCATAGACGAGGAGGGGACCGACGAGGACAGTGAGACACCAGCCACCAGCGACAATGGATCTGGCTCGACGGCGAACAATGGTCCGTACATGCCGCTACCGCCGCATTTACTGGACGAGGATGATGATTTGGATTTTGAGGATCAATATCTGCTGGGTTAG
Protein Sequence: MEGMDLWTSMFSADFEEGEEEIEQYANENGVDSNPAGDGDDILPEDDENDAEDAAEEEEEEATGRGNGKTKEPDLDDDDAIFDFDLEPIVSIGEPQPPPVLAPTGPLGSPVRPMLRHSLPARQGRPKEVCPTGGLTRPTTSQINATDANGIPINYELGVIYICPACGAEFRQQDLWKRHMNQMHQFNTRRGLNFMAMDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGFNLAGRKTRVREPRTEQMQRKDPFPEEDSEQNDVLEPETETMPPMLEEEAPQRRRKKRYQGGPSGDGGADLCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFISVDMQMQCLECKKIVIPNTIKTLRAHKFTHLPQPEWLRCKLCYKGYTEHHELVNHLLKQHHLETLMPEESPDPSPVKRTDGGGDDWEDNVNGSVFDDVSPHFEDVPRRGGRIGSDDMYEPHIDYLCPQCGKEFIEKKHWRTHVVQVHGMNDVTKLNFAVINDRQLKCTECAKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGYVPHKNFRMAGRGARLLGAPKQQRKQIVTLGKETYEIIFLDEEQTHSSVDEENDFGEQMQMADEEDLPTVSTDLPPPNPNRYKCVECGTLFPTQVALKLHISEAHTHALRDPPQYGGSKKLDPSQGKEEASKKRRLGAGPAAALIPAAAAATSSPSAGTVEQNYIFLCPSCGEEYKTQFEWRRHINEAHNFDKRQYLNMRQLDKYRYQCTQCNDVVCNSKLKGLQDHHFRHLPFRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERETPWRELQTKPQYSYVQSKEKDRGTVAKSRPQSPSPAVVASSSGSSASASSRPLWPQSEKRPTRPAGLNTLEDSISYHNAVDMDFITYYCPKCNKNFDSHAFWRKHIVEHHNFNSREGLNFRQIDMHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPSAEKVFDDEEQETGGVASAEDEDAEASAYRLMCPQCGDEFTTSSQAAWRNHLNVSHGLGKQPLHIRKVGEGLYRCYDCDEELATKSKGVLQQHRFKHMPHAAYILCQLCASGTDEKAAEVHSMQELHHHIREHHPAVEESDERLQKVRQLIDEEGTDEDSETPATSDNGSGSTANNGPYMPLPPHLLDEDDDLDFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603660;
90% Identity: iTF_00611634;
80% Identity: -