Basic Information

Insect: Drosophila obscura
Gene Symbol: -
Assembly: GCA_018151105.1
Location: NW:11512020-11516735[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.5e-05 0.0046 17.0 0.1 1 23 159 182 159 182 0.96

2 14 0.0016 0.097 12.9 3.1 2 23 231 253 227 253 0.90

3 14 0.0069 0.42 10.9 0.8 1 23 342 365 342 365 0.93

4 14 0.3 18 5.7 5.4 2 23 414 436 413 437 0.95

5 14 0.0013 0.078 13.2 0.6 1 23 500 523 500 523 0.88

6 14 6.7 4.1e+02 1.5 0.1 2 14 542 554 541 566 0.83

7 14 0.00063 0.038 14.1 3.3 2 23 574 596 574 596 0.96

8 14 0.0005 0.031 14.4 0.0 1 23 681 704 681 704 0.95

9 14 0.00063 0.039 14.1 0.2 1 23 765 788 765 788 0.93

10 14 0.0011 0.064 13.4 2.2 2 23 838 860 837 860 0.97

11 14 0.003 0.18 12.0 3.8 1 23 951 973 951 974 0.94

12 14 0.048 2.9 8.2 1.5 1 21 1026 1046 1026 1047 0.95

13 14 0.36 22 5.5 0.0 2 23 1088 1112 1087 1112 0.81

14 14 0.98 60 4.1 0.6 1 23 1129 1153 1129 1153 0.73

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.5e-05	0.0046	17.0	0.1	1	23	159	182	159	182	0.96
2	14	0.0016	0.097	12.9	3.1	2	23	231	253	227	253	0.90
3	14	0.0069	0.42	10.9	0.8	1	23	342	365	342	365	0.93
4	14	0.3	18	5.7	5.4	2	23	414	436	413	437	0.95
5	14	0.0013	0.078	13.2	0.6	1	23	500	523	500	523	0.88
6	14	6.7	4.1e+02	1.5	0.1	2	14	542	554	541	566	0.83
7	14	0.00063	0.038	14.1	3.3	2	23	574	596	574	596	0.96
8	14	0.0005	0.031	14.4	0.0	1	23	681	704	681	704	0.95
9	14	0.00063	0.039	14.1	0.2	1	23	765	788	765	788	0.93
10	14	0.0011	0.064	13.4	2.2	2	23	838	860	837	860	0.97
11	14	0.003	0.18	12.0	3.8	1	23	951	973	951	974	0.94
12	14	0.048	2.9	8.2	1.5	1	21	1026	1046	1026	1047	0.95
13	14	0.36	22	5.5	0.0	2	23	1088	1112	1087	1112	0.81
14	14	0.98	60	4.1	0.6	1	23	1129	1153	1129	1153	0.73

Sequence Information

Coding Sequence: ATGGAAGGAATGGACCTTTGGACATCCATGTTCTCGGCAGACTTTGAGGAGGGCGAGGAGGAGATCGAGCATTATGCGAATGAAAACGGCCTGGACAGCAATCCTGCCGGCGACGGTGATGACATTCTGCCCgaggatgatgataatgatgcgGAAGACgttgaggaggaggaggaggagccaacTGGCCGGGGTAATGGAAAGACAAAAGAGCCCGATTTAGATGATGATGCCATATTTGATTTCGATCTGGAGCCGATTGTAAGTATTGGCGAGCCACAGCCCCCTCCACTGCTGGCGCCTACTGGTCCAGTTGGCTCACCAGTGCGTCCCATGCTTCGCCACTCAATGCAGGCCAGGCAGGGCCGGCCTAAGGAGGTGTGTCTGACGGGAGGGCTCACGCGGCCCACCACCTCGCAGATCAATGCAACCGATGCGAACGGGATTCCCATAAACTATGAGCTGGGCGTCATCTATATCTGCCCCGCATGCGGAGCAGAATTCCGGCAGCAGGATCTCTGGAAACGGCACATGAACCAAATGCACCAGTTCAACACGCGGCGTGGCCTTAACTTCATGGCCATGGACAAGCTCTATCATCGGTGCCTGGAGTGTAACAAGCGCATCGCCATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACCCACTTGCCGTTTAGGTGCACCAAGTGCTACATCTGCAAGCGGGAGTACAAATACAGACAAGACCTGATGGTTCACCTGAGGATGGTCCATTGCGACGAAGTGGTGGCCATGATGCGGGAGGGCTTCAACTTGGCGGGACGCAAGACGCGGGTACGGGAGCCGCGCACAGAGCAAATGCAGCGCATGGATCCGTTCCCAGAGAAGGACAATGAGCAAAACGATCTTCTCGAGCCGGAGACTGAGACTATGCCACCCATGCTGGAGGAGGAAGCTCCGCAGAGGCGTCGGAAAAAGCGCTACCAAGGAGGTCCCTCTGGCGACGGAGGTGCGGATCTTTGCGAGGATTACATCCACTACATGTGCCCCGATTGCGGCACTGAGTGCGACACCCACGCCCAGTGGAGTCAACACATTGAATTTGTCCACGACTACGTCAGCCGCAGGGGTCTCAACTTCATCAGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTCATCCCCAACACCATTAAGACGCTGCGGGCCCACAAGTTCACGCATCTGCCGCAGCCCGAGTGGCTGCGCTGCAAGCTGTGCTATAAGGGCTACACGGAACACCACGAGCTGGTCAGTCATCTGCTGAAGCAACACCACCTAGAGTCGCTCATGCCAGAGGAGTCGCCGGATCCATCACCCGTCAAAAGGACAGATGGTGGAGGCGACGACTGGGAGGACAATGTAAACGGCAGCGTCCTCGATGACGTTTCGCCGCACTTTGAGGATGTACCCCGACGGGGAGGACGCATCGGGAGCGATGACATGTACGAGCCACACATCGACTACCTATGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCATGTGGTGCAGGTGCATGGCATGAACGATGTGACAAAGCTCAACTTTGCGATAATCAACGATCGCCAGCTGAAGTGCACGGAGTGCTCCAAAATCATAACGAACGCCTACGGCATACAGAATGCCCAGCAGCACAGGATCACGCACCTTCCATTCAAGGCATACGCCAGGTGTCGCAAGTGCCACAAGTCTTACACAGATCGCAAGGGTCTGGTCAAGCATCTGGCCACCTACCATCGTGTGGGCTACGTTCCgcacaaaaatttcaaaatggCCGGACGAGGAGCCCGGCTGTTTGTGTCGCCCAAGCAGCAGCGCAAACAGATTGTGACCCTGGGAAAAGAGACTTACGAGATAATCTTCCTTGATGAAGAGCAGACGCACTCAAGTGTCGACGAGGAGAACGACTTTGGAGAGCAGATGCAGATGGCGGATGAGGAGGACTTGCCCACTGTCAGTACCGACTTGCCGCCGCCCAATCCGAATCGCTACAAGTGCGTTGAGTGCGGAACATTATTCCCCACTCAAGTGGCTCTCAAGTTGCACATCAGTGAGGCACATACACATGCGTTGCGGGATCCCCCTCAGTACGGGGGATCGAAGAAGTTGGACAAATCCCAGGGCAAAGAGGAGGCATCCAAGAAGAGGAGATTAGGAGcgggatcagcagcagcattaatACCATCACCATCAGCGGCCACAAGTAGCCCATCGCCGGGCACGGTAGAGCAGAACTACATATTCCTGTGCCCCTCGTGCGGCGAGGAGTACAAGACACAGTTCGAGTGGCGCCGTCACATCAACGAGGCCCACAACTTCGACAAACGGCAGTATCTGAATATGCGGCAGCTGGACAAGTACCGCTACCAGTGCACCCAGTGCAACGACATTGTGTGCAACTCCAAGTTGAAGGGCCTGCAGGACCACCATTTTCGGCATCTGCCCTTCCGCCTGTACCTCAAGTGCCTCGTGTGCGGCACCTGCTATAACCACAAGCCCAACATAGCCGCCCATCTGAGGACGCGGCACAACATCTACGAGCGCGAAACGCCATGGCGGGAGCTGCAAACCAAGCCCCAGTACTCGTATGTTCAGTCCAAGGAGAAAGACAGGGGTACGGTCGCCAAAAGCAGGCCACAATCACCCTCGCCCGCAGTTGTCGCCTCTTCCTCCGGCTCCAGCGCCAGCAGTCGCCCGCTCTGGCCGCAGTCCGAGAAGCGTCCCACTCGGCCGGCCGGACTTAACACCCTGGAGGACAGCATCTCATACCACAATGCGGTGGACATGGACTTCATCACCTACTACTGCCCCAAGTGCAACAAGAATTTCGACTCTCATGCCTTCTGGCGCAAGCACATCGTGGAGCATCACAACTTCAACAGTCGCGAGGGCCTAAACTTCCGGCAGATCGACATCCACCACTACTTGTGCCTGGAGTGCTACAAGCGTGTCACCGTCACTCATACCAAGGGCGCCATCGGGCAGCTCCAGTCGCACAAGTTCCGCCACCTGCCGTACCGCTCCTTCAAGTGTCTCACCTGCAACGGAGAGTTTGTCCGCAAGCAGATGTTCTTCAAGCATCTTAATCGGGACACCAATCGGTGCGACAACAAGCCCAGCGCCGAAAAGGTGTTTGATGACGAGGATCAGGAAACGGGTGGCGTTGCCTCCGCCGAAGATGAAGACGTAGAAGCATCAGCCTATCGGCTAATGTGCCCCCAGTGCGGCGACGACTTCACCACCAGCAGCCAGGCGGCATGGCGCAACCACCTTAACGTTGCCCACGGCCTGGGCAAGCAGCCTCTGCATATTCGGAAGGTGGGCGAGGGGCTCTACCGCTGCTACGACTGCGACGAGGAGTTGGCTACGAAGAGCAAGGGTGtcctgcagcagcaccgcTTCAAGCATATGCCCCATGCAGCCTACATTCATTGCCAACTTTGCGAGAGCGGGGCGGATGAGAAGGCGGCTGAAGTGCACAGCATGCAGGAGTTACATCATCACATCCGCGAGCACCATCCTGCCGTGGAAGAGAGTGACGAGAGGCTGCAGAAGGTGCGCCAACTCATAGACGAGGAGGGGACCGACGAGGACAGTGAGACACCAGCAAACAGCGACAATGGATCTGGCTCGACGGCAAACAATGGTCCGTATATGCCGCTACCGCCGCATTTActggatgaggatgatgatttGGATTTTGAGGATCAATATCTGCTGGGATAG
Protein Sequence: MEGMDLWTSMFSADFEEGEEEIEHYANENGLDSNPAGDGDDILPEDDDNDAEDVEEEEEEPTGRGNGKTKEPDLDDDAIFDFDLEPIVSIGEPQPPPLLAPTGPVGSPVRPMLRHSMQARQGRPKEVCLTGGLTRPTTSQINATDANGIPINYELGVIYICPACGAEFRQQDLWKRHMNQMHQFNTRRGLNFMAMDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGFNLAGRKTRVREPRTEQMQRMDPFPEKDNEQNDLLEPETETMPPMLEEEAPQRRRKKRYQGGPSGDGGADLCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFISVDMQMQCLECKKIVIPNTIKTLRAHKFTHLPQPEWLRCKLCYKGYTEHHELVSHLLKQHHLESLMPEESPDPSPVKRTDGGGDDWEDNVNGSVLDDVSPHFEDVPRRGGRIGSDDMYEPHIDYLCPQCGKEFIEKKHWRTHVVQVHGMNDVTKLNFAIINDRQLKCTECSKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGYVPHKNFKMAGRGARLFVSPKQQRKQIVTLGKETYEIIFLDEEQTHSSVDEENDFGEQMQMADEEDLPTVSTDLPPPNPNRYKCVECGTLFPTQVALKLHISEAHTHALRDPPQYGGSKKLDKSQGKEEASKKRRLGAGSAAALIPSPSAATSSPSPGTVEQNYIFLCPSCGEEYKTQFEWRRHINEAHNFDKRQYLNMRQLDKYRYQCTQCNDIVCNSKLKGLQDHHFRHLPFRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERETPWRELQTKPQYSYVQSKEKDRGTVAKSRPQSPSPAVVASSSGSSASSRPLWPQSEKRPTRPAGLNTLEDSISYHNAVDMDFITYYCPKCNKNFDSHAFWRKHIVEHHNFNSREGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPSAEKVFDDEDQETGGVASAEDEDVEASAYRLMCPQCGDDFTTSSQAAWRNHLNVAHGLGKQPLHIRKVGEGLYRCYDCDEELATKSKGVLQQHRFKHMPHAAYIHCQLCESGADEKAAEVHSMQELHHHIREHHPAVEESDERLQKVRQLIDEEGTDEDSETPANSDNGSGSTANNGPYMPLPPHLLDEDDDLDFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603660;
90% Identity: iTF_00611634;
80% Identity: -