Dtes003407.1
Basic Information
- Insect
- Drosophila testacea
- Gene Symbol
- lrrfip2
- Assembly
- GCA_035043265.1
- Location
- JAWNND010000229.1:4090660-4093558[+]
Transcription Factor Domain
- TF Family
- LRRFIP
- Domain
- LRRFIP domain
- PFAM
- PF09738
- TF Group
- Unclassified Structure
- Description
- LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 5.2e-120 1.1e-115 386.3 26.3 1 299 30 315 30 316 0.99 2 2 0.028 5.9e+02 -0.3 3.3 209 241 334 365 318 389 0.60
Sequence Information
- Coding Sequence
- ATGGATACCACAAGCACCACCGGAAGGCGGCGAAACAATTTGTGTGCTAATGCCGAGGATAATGCTCTCGACCAGATTACGAAGGAGGCCGAAGCGCGTTTAGCAGCTCGTCGTCAAGCAAGAGTTGAAGCTCGTGAGATACGTATGCGAGAGCTTGAGCGCCAACAAAAGGAACAGGAGCAAAATGCTGACCGTGCCTTTGATATGCATAATATCAGTGGCAATGATACACATCCAACACGTCTTGCCTACGGTGGTCTTATAAACTTGACGCGTGCAGGAGCTTCCCGCCGCAGTAGTGAGGATTCATTAGAGGAGGAGGGTCGCAGCTTTCGTGACGTCAAGCATGAGCTTAAAGATGTTGAGGAACGTTTCCGGAAGGCAATGATAACGAATGCACAGTTGGACAATGACCGGTCATCTCAAACTTATGAAGTCAAATTACTGAAGGATAAAAGTGAAACAATGCAAGAGGCTTTTGCCCAACTGCAGCGCGagcttaaaaacaaattgcgtGATTGCAATGCACTCAAACGCAATTTGGATCGCACAACACTTGAATTGAGCTTAGTCCAAGGCCAATTAAGCGAACGCGATACGCTTATAGCAGAACACggtcttgttattgttgccattgAGAATACGGACGGTAGTGACGCCAAAAGGGCATTAGTTAGTGTTGAAAATGCCAATATCTTAGCGACCGTTCAGGGATCGCTTGATGTAAGACTTAAAAAGTTTACAGAAGAAAAACAGCGACTTTTAAAGGAAGTACAAGTGCTGCATGAACAGTTAGATGCTTATAAAACCGAAGGCAGGGCGGGTCGCAGTAGTTCGCTGAATGGATCCTTAGGATATGACGATGATTATGATGTTCAAAGGGAAGCTAACAAGATCGTATcagattataaatataaactgcAAAAAGCCGAACAGGAAATCGCTAATCTACAAGCGAGTTTATCACGTTCGGAATCGCAAGTAATTCGATATAAAAGCACGGCGGAAGCAGCGGAAAAAGTAGAGGCAGAATTGAAAGTGGAACGGCGTAAACTGCAACGTGAGCATCGAGAAATACTGGAGCGCCTTGAAGAAGCAGAAACTGCAAATAATCATTTACTGAAACGTCTTGATAAactaaaaaatgcaaaaagcacTATCTTGAAGGATTTATGA
- Protein Sequence
- MDTTSTTGRRRNNLCANAEDNALDQITKEAEARLAARRQARVEAREIRMRELERQQKEQEQNADRAFDMHNISGNDTHPTRLAYGGLINLTRAGASRRSSEDSLEEEGRSFRDVKHELKDVEERFRKAMITNAQLDNDRSSQTYEVKLLKDKSETMQEAFAQLQRELKNKLRDCNALKRNLDRTTLELSLVQGQLSERDTLIAEHGLVIVAIENTDGSDAKRALVSVENANILATVQGSLDVRLKKFTEEKQRLLKEVQVLHEQLDAYKTEGRAGRSSSLNGSLGYDDDYDVQREANKIVSDYKYKLQKAEQEIANLQASLSRSESQVIRYKSTAEAAEKVEAELKVERRKLQREHREILERLEEAETANNHLLKRLDKLKNAKSTILKDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00336724;
- 90% Identity
- iTF_00472354;
- 80% Identity
- -