Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: GFI1B
Assembly: GCA_014743375.2
Location: NC:15301088-15304197[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 1.5e-05 0.00085 19.4 0.5 1 23 279 302 279 302 0.95

2 11 0.0035 0.2 11.9 3.3 3 23 314 334 313 334 0.97

3 11 9.5e-06 0.00055 20.0 2.3 2 23 344 366 344 366 0.91

4 11 2.9e-05 0.0016 18.5 0.5 1 23 462 485 462 485 0.95

5 11 8.5e-06 0.00049 20.1 1.2 3 23 497 517 496 517 0.99

6 11 1.8e-05 0.001 19.1 0.5 2 23 527 549 527 549 0.92

7 11 0.00013 0.0074 16.4 0.1 1 23 555 577 555 577 0.95

8 11 0.00032 0.018 15.2 0.7 1 23 583 605 583 605 0.97

9 11 0.0013 0.074 13.3 0.8 1 23 610 632 610 632 0.98

10 11 6.7e-06 0.00038 20.5 1.4 1 23 638 660 638 660 0.97

11 11 0.0063 0.36 11.1 3.4 1 23 666 689 666 689 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	1.5e-05	0.00085	19.4	0.5	1	23	279	302	279	302	0.95
2	11	0.0035	0.2	11.9	3.3	3	23	314	334	313	334	0.97
3	11	9.5e-06	0.00055	20.0	2.3	2	23	344	366	344	366	0.91
4	11	2.9e-05	0.0016	18.5	0.5	1	23	462	485	462	485	0.95
5	11	8.5e-06	0.00049	20.1	1.2	3	23	497	517	496	517	0.99
6	11	1.8e-05	0.001	19.1	0.5	2	23	527	549	527	549	0.92
7	11	0.00013	0.0074	16.4	0.1	1	23	555	577	555	577	0.95
8	11	0.00032	0.018	15.2	0.7	1	23	583	605	583	605	0.97
9	11	0.0013	0.074	13.3	0.8	1	23	610	632	610	632	0.98
10	11	6.7e-06	0.00038	20.5	1.4	1	23	638	660	638	660	0.97
11	11	0.0063	0.36	11.1	3.4	1	23	666	689	666	689	0.98

Sequence Information

Coding Sequence: ATGTCGAGTATTTCCGCATCAAAGGAAGCCACCCGCAAAGATCCAGCAATTTGGCACCGATGGTGTCGCCTGTGTGCCCAAGATCATCTGACCAATCGGAATGTGTACTCCAGGGAGGAGCATCAGAACTCGTGGACGAGCAAGTTGGCCATGACCGTTGGCAAATACTTCTGGGTGGATATCAAAAAGGAGGATGAGCTAAGCAATTATCTGTGTTCCGAATGCTTCACTTTGATGGATTGCCTCATGGAATTCTCGGAGAGAGTTCGCAAAGTGCAGACCCTTTTCAACAGATTGCAGGCCCTAAAACCAAATACTTCGGTAAACTATGAGGAACTACGAGCAGACTGCGGTTTGGCCACCGATGAATGGAAGCATATTATGTACAGAGCAGTGGTACTTCCTCCCCCGAAAGAAGAGGAGTTCATTGATGAGGACCAACCAATAGTCGTGGAAGAACTGAAAAACCAAGAATTTGCCCAGGAGCTACATATCGCTGGAGAGGAACTACAAATCGTTGGAATGGAAGAGGAAATCTTAGAAGACGGAGGTGAGCACCTCGCGGAGGAAGAGGTCGAAACAGTGGAGGAGGAGGTGCAGCAACAGGAACCCTCAGATTGCTTGGTAGAAGTGGATCGCATCGCAGAGGATGAGGACTACGTCGAAGCATCGAAGATTATAGTAGAAAGCCAAGTTGACGATTTCCACGTTGAAACGTATGAAGTAATATCTCAATCACGCCCAGAAGAACTCATTAAATCGAAAGCTATCGAGGAAACTATAGAATCCGAGGAAGATACCCATGAAGATGCAATTTCCGTGGAGCCAACCAACTATAAATGCAGCATTTGCAATAAGTCGTACATAAAACCCATGGCCTACAAGCGACACATGGAGGAAGTCCACAACACTGTGCCCAAAGATCTACCACAACTGCTGTGCAACCGGTGCGGATTATGCTTTCCCACGGCCACCCAGCTGGCCTCCCACTACTGCAACCATTTACCCGCCAAAATGAAGTCGGATAACTCCTGTCCGCACTGTGAAAAGCATTTTACCACTCCGGCATCCCTTAAGCGACATATAGATGGTTTTCACAAGCAGATCAAGCCTTATGTCAGCGAAACCTCAGATTGCCTTGTTGAAGTCGAAAACATCCCGGAAGAGGACTACATCGAAGAATCGCAGATAATAGAAGAAAGCCAAGTGGAAGATTTCCAGATTGAAACGTATGAAGTAATATCCCAAGCACGGCCAGAAGAACTCCTTAAATCGAAAGCAGTCGAAGAAACTATAGAGTCCGAGGACGATACACATGAAGATCTTTTATCTGAGCATCTCATAGAAGATGAAGAAGACGAGATTCCAGAAGAGCCAACCATCTACAAATGCAGCATTTGCAATAAGCCTTACAAGTTACCCAAGGCCTATAAGCGACACATGGAAGAAGTCCACAACACCGTGCCCAAAGATCTACCACAGCTGTTATGCAACCAGTGCGGACTATGCTTTCCCTCGGCCACCCAGCTGACCGCCCACTACCGAACCCATTTACCCGCCATAACTAAGTCCGATAACTCCTGTCCGCACTGCGATAAGCGTTTGACCACACCGGGAACACTGAAGCGTCATATAGAGGGGGTTCACAAGCAGATCAAGCCCTATGCTTGCGACATCTGCGGCAAGAGCTTCAACTATGTCACCGGGCTCAAAGATCACAAGGTGGTCCACACCGAGGAGTGTCCCTTCGAGTGTCCCGTGTGCTTGCGACGCTTTAAAAACAAGGCTAGATTAAAGATCCATTCCGATACTCACAGTGCCCAAATCTACGAGTGTGCTATATGCGGCGTGAAGCTCAAGACCCGTCGCACCTTCAACAAGCACAAATTGGTCCACTCAGATGAACGGCAATATAAGTGTGATGTCTGTGGATCAACGTTCAAGCGGAGCAAGACCCTAAAGACGCATCTCATCCTGCACACTGGCATTCGGCCGTACAAGTGCAACTTCTGCGGAATAGACTTCTCCAATGGCTCCAATTGTCGATCGCACAAGCGAAAGGCGCATCCAAAGGAACTGGCCGAGGAGGAATCGCGCGGAGTCTCGCGGTCCACGCTACTTCCTATGCTAGATGAACTTACCAAGGCATCCAAGCTCATTAAAACACCCGCAAAGCCCAGCAAAAACAAGGGAAGTAGGCCAAAAGTTCCGCCCAAAGCTGAATCTTCCTCAAAGGACACTGATGGGAATGCTATCCTTTACGAACTTGTCGAGGAGCTTGAATACTCCTAG
Protein Sequence: MSSISASKEATRKDPAIWHRWCRLCAQDHLTNRNVYSREEHQNSWTSKLAMTVGKYFWVDIKKEDELSNYLCSECFTLMDCLMEFSERVRKVQTLFNRLQALKPNTSVNYEELRADCGLATDEWKHIMYRAVVLPPPKEEEFIDEDQPIVVEELKNQEFAQELHIAGEELQIVGMEEEILEDGGEHLAEEEVETVEEEVQQQEPSDCLVEVDRIAEDEDYVEASKIIVESQVDDFHVETYEVISQSRPEELIKSKAIEETIESEEDTHEDAISVEPTNYKCSICNKSYIKPMAYKRHMEEVHNTVPKDLPQLLCNRCGLCFPTATQLASHYCNHLPAKMKSDNSCPHCEKHFTTPASLKRHIDGFHKQIKPYVSETSDCLVEVENIPEEDYIEESQIIEESQVEDFQIETYEVISQARPEELLKSKAVEETIESEDDTHEDLLSEHLIEDEEDEIPEEPTIYKCSICNKPYKLPKAYKRHMEEVHNTVPKDLPQLLCNQCGLCFPSATQLTAHYRTHLPAITKSDNSCPHCDKRLTTPGTLKRHIEGVHKQIKPYACDICGKSFNYVTGLKDHKVVHTEECPFECPVCLRRFKNKARLKIHSDTHSAQIYECAICGVKLKTRRTFNKHKLVHSDERQYKCDVCGSTFKRSKTLKTHLILHTGIRPYKCNFCGIDFSNGSNCRSHKRKAHPKELAEEESRGVSRSTLLPMLDELTKASKLIKTPAKPSKNKGSRPKVPPKAESSSKDTDGNAILYELVEELEYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486718; iTF_00486691; iTF_00604990; iTF_00604991;
90% Identity: iTF_00604990;
80% Identity: -