Basic Information

Gene Symbol
-
Assembly
GCA_013340165.1
Location
WWNF01000009.1:4843001-4845470[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 1.4e-05 0.00094 19.4 0.5 1 23 279 302 279 302 0.95
2 11 0.0008 0.055 13.8 3.3 3 23 314 334 313 334 0.98
3 11 1.6e-05 0.0011 19.2 3.1 2 23 344 366 344 366 0.91
4 11 2.7e-05 0.0018 18.5 0.5 1 23 461 484 461 484 0.95
5 11 4.6e-06 0.00031 20.9 1.0 3 23 496 516 495 516 0.99
6 11 1.7e-05 0.0011 19.1 0.5 2 23 526 548 526 548 0.92
7 11 5.2e-05 0.0035 17.6 0.2 1 23 554 576 554 576 0.96
8 11 0.00029 0.02 15.2 0.7 1 23 582 604 582 604 0.97
9 11 0.00051 0.035 14.4 1.4 1 23 609 631 609 631 0.98
10 11 6.2e-06 0.00042 20.5 1.4 1 23 637 659 637 659 0.97
11 11 0.0059 0.4 11.1 3.4 1 23 665 688 665 688 0.98

Sequence Information

Coding Sequence
aTGTCGAGTACTCCTGCAGAAAAGGAAGCCACCCATGAAGATCCAGCAATTTGGCACCGATGGTGTCGCCTGTGTGCCCAAGATCATCTGACCAACCGGAATGTGTACTCCAGGGAGGAGCATCAGAACTCGGGGACGAGCATGTTGGCCATGACCGTTGGCAAATACTTCTGGGTGGATATCAAAAAGGAGGATGAGCTGAGCAATTATCTGTGTTCCGAATGCTTCACTTTGATGGATTGCCTCATGGAATTCTCGGAGAGAGTTCGCAAAGTGCAGACCCTTTTCAACAGACTGCAGGCCCTAAAACCGGATACTTCGGTAAACTATGAGGAACTACGAGCAGACTGCGGATTGGCCACCGATGAATGGAAGCATATTATGTACAGAGCAGTGGTACTTCCTCCCCCTAAAGAAGAAGAGTTCATTGATGAGGACCAACCAATAGTCGTGGAAGAACTGAAAAACCAAGAATTTGTCCAGGATCTGCATATCGCTGGAGATGAACTACAAATCGTTGGAATGGAAGAGGAAATCTTAGAAGACGGAGGTGAGCACCTCGTGGAGGAAGAGGTCGAAAcagtggaggaggaggtgcagCAACAGGAACCCACCGATTGCTTGGTAGAAGTGGATCGCAGCGCAGAGGATGAGGACTACATCGAAGCATCGAAGATAATAGTAGAAAGCCAAGTTGAAGATTTCCACGTTGAAACATATGAAGTAATATCCCAAGCACGCCCAGAAGAACCCCTTAAATCGAAAGCAGTCGAAGAAACTATAGAATCCGAGGAAGATACCCATGCGGATGAAATTTCCGTGGAACCAACCAATTATAAATGCAGCATTTGCAATAAGTCGTACATAAAACCCATGGCCTACAAGCGACACATGGAGGAAGTCCACAACACTGTGCCCAAAGATCTACCACAACTGCTATGCAACCGGTGCGGATTATGCTTTCCCACAGCCACCCAGCTAGCCTCCCACTACTGCACCCATTTACCCGCCAAAATGAAGTCTGATAACTCCTGTCCGCACTGCGAAAAGCATTTTACCACTTCGGCATCCCTTAAACGACATATAGATGGGTTTCACAAGCAGATCAAGCCTTACGTCGGCGAAACCTCAGATGGCCTTGTTGAAGTGGAAAACATCCCGGAAGAGGACTACATCGAAGAATCGCAGATAATAGAAGAAAGCCAAGTAGAAGATTTCCAGATTGAAACATATGAAGTAATATCCCAAGCACGCCCAGAAGAACTCCTTAAATCGAAAGCAGTCGAAGAAACTATAGAGTCCGAGGACGATACCCATGAAGATCTTTTATCTGAGCATCTCATAGAAGATGAAGATGACGAGATTCCAGATCCAACCATCTACAAATGCAGCATTTGCAATAAGCCTTACAAGTTACCCAAGGCCTATAAGCGACACATGGAAGAGGTCCACAACACCGTGCCCAAAGATCTACCACAGCTGTTATGCAACCAATGCGGACTATGCTTTCCCTCGGCCTCCCAGCTGAACGCCCACTACCGAAGCCATTTACCCGCCATAACTAAGTCCGATAACTCCTGTCCGCACTGCGATAAGCGTTTGACCACACCGGGAACACTGAAGCGACACATAGAAGGGGTTCACAAGCAGATCAAGCCCTATGTTTGCGACATCTGCGGCAAGAGCTTCAACTATGTCACCGGTCTCAAAGATCACAAGGTGGTCCACACCGAGGAGTGTCCCTTCGAGTGTCCCGTGTGCTTGCGACGCTTTAAAAACAAGGCTAGATTAAAGATCCATTCCGATACTCACAGTGCCCAAATCTACGAGTGTACAATATGCGGCGTGAAACTCAAGACCCGTCGCACCTTCAACAAGCACAAATTGGTCCACTCAGATGAACGGCAATATAAGTGTGATGTCTGTGGATCAACGTTCAAGCGGAGTAAGACCCTAAAGACGCATCTCATCCTGCACACTGGCATTCGGCCGTACAAGTGCAACTTCTGCGGAATAGACTTCTCCAACGGCTCCAATTGTCGATCGCACAAGCGAAAGGCGCATCCGAAAGAACTGGCCGAGGAGGAATCGCGCGGAGTCTCGCGGTCCACGCTACTTCCTATGCTAGATGAACTTACCAAGGCATCCAAGCTCATAAAAACACCTGCAAAACCCAGCAAAAACAAGGGAAGTAGGCCAAAAGTTCCGCCCAAAGCTGAATCTTCCTCAAAGGACACTGATGGGAATGCTATCCTTTACGAACTTGTCGAGGAGCTTGAATATTCCTag
Protein Sequence
MSSTPAEKEATHEDPAIWHRWCRLCAQDHLTNRNVYSREEHQNSGTSMLAMTVGKYFWVDIKKEDELSNYLCSECFTLMDCLMEFSERVRKVQTLFNRLQALKPDTSVNYEELRADCGLATDEWKHIMYRAVVLPPPKEEEFIDEDQPIVVEELKNQEFVQDLHIAGDELQIVGMEEEILEDGGEHLVEEEVETVEEEVQQQEPTDCLVEVDRSAEDEDYIEASKIIVESQVEDFHVETYEVISQARPEEPLKSKAVEETIESEEDTHADEISVEPTNYKCSICNKSYIKPMAYKRHMEEVHNTVPKDLPQLLCNRCGLCFPTATQLASHYCTHLPAKMKSDNSCPHCEKHFTTSASLKRHIDGFHKQIKPYVGETSDGLVEVENIPEEDYIEESQIIEESQVEDFQIETYEVISQARPEELLKSKAVEETIESEDDTHEDLLSEHLIEDEDDEIPDPTIYKCSICNKPYKLPKAYKRHMEEVHNTVPKDLPQLLCNQCGLCFPSASQLNAHYRSHLPAITKSDNSCPHCDKRLTTPGTLKRHIEGVHKQIKPYVCDICGKSFNYVTGLKDHKVVHTEECPFECPVCLRRFKNKARLKIHSDTHSAQIYECTICGVKLKTRRTFNKHKLVHSDERQYKCDVCGSTFKRSKTLKTHLILHTGIRPYKCNFCGIDFSNGSNCRSHKRKAHPKELAEEESRGVSRSTLLPMLDELTKASKLIKTPAKPSKNKGSRPKVPPKAESSSKDTDGNAILYELVEELEYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00602762;
90% Identity
iTF_00604990;
80% Identity
-