Basic Information

Insect: Drosophila biarmipes
Gene Symbol: gfi1b
Assembly: GCA_018148935.1
Location: JAECYG010000101.1:25002986-25010976[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.8e-06 0.00016 21.7 0.9 1 23 282 305 282 305 0.95

2 10 2.3e-05 0.0014 18.7 0.7 2 23 319 341 318 341 0.93

3 10 1.1e-05 0.00068 19.7 0.5 1 23 437 460 437 460 0.95

4 10 2.9e-05 0.0017 18.5 1.1 3 23 472 492 471 492 0.99

5 10 1.9e-06 0.00011 22.1 0.7 2 23 502 524 502 524 0.92

6 10 1.9e-05 0.0011 19.0 0.2 1 23 530 552 530 552 0.97

7 10 0.0003 0.018 15.2 0.7 1 23 558 580 558 580 0.97

8 10 0.00095 0.057 13.7 1.0 1 23 585 607 585 607 0.98

9 10 5.8e-06 0.00035 20.6 0.4 1 23 613 635 613 635 0.97

10 10 0.006 0.36 11.2 3.4 1 23 641 664 641 664 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.8e-06	0.00016	21.7	0.9	1	23	282	305	282	305	0.95
2	10	2.3e-05	0.0014	18.7	0.7	2	23	319	341	318	341	0.93
3	10	1.1e-05	0.00068	19.7	0.5	1	23	437	460	437	460	0.95
4	10	2.9e-05	0.0017	18.5	1.1	3	23	472	492	471	492	0.99
5	10	1.9e-06	0.00011	22.1	0.7	2	23	502	524	502	524	0.92
6	10	1.9e-05	0.0011	19.0	0.2	1	23	530	552	530	552	0.97
7	10	0.0003	0.018	15.2	0.7	1	23	558	580	558	580	0.97
8	10	0.00095	0.057	13.7	1.0	1	23	585	607	585	607	0.98
9	10	5.8e-06	0.00035	20.6	0.4	1	23	613	635	613	635	0.97
10	10	0.006	0.36	11.2	3.4	1	23	641	664	641	664	0.98

Sequence Information

Coding Sequence: ATGTCGAGTACTTCCGCAGCAAATGTAGCCACCCATGAAGATCCAGCAATTTGGCACAAATGGTGTCGCCTATGTTCCCAAGATCATCCGACCAACCGGAATGTGTACTCCAGGGAGGAGCAGCCGAACTCCTGGACGAGCATGTTGGCCATGACCGTGGGCAAATACTTCTGGGTGGATATCAAAAAGGAGGATGAGCTGAGCAACTACCTGTGCTCAGAGTGCTTCACATTGATGGATTGCCTCATGGAATTCTCGGAGAGAGTTCGCAAAGTACAGATCCTCTTCAACAGATTGCAGGCCTTAAAACCGGAAGCTGTGGTAAACTATGAGGAACTACGAGAGGATTGCGGCTTGGCCAGCGACGAATGGAAGCATATAATGTACAGAGCAGTGGCACTTCCTCCTTACAAACAAGAAGAACTCAAAACCAATGGAATGGAACAGCAAGTTATAGTGATAGAACAGGAACAGCAGCAAACTCAAGAGTTTGTCCAGGAGCTACATATCGCTGGAGAGGCACTACAAACCGCTGGAATGGAAGAGGAAATCCTAGAGGACGAGGGTGAGCACCTTGCAGAGGAAGAGGTCGAAACTATGGAGGAGGAAGTGCAGCAGCAGGAAACCTCAGATTGCCTGGTTGAAGTGGATCGCATAGCGGAGGAGGAATTCATCGAAGAATCAAGGCTAACAGAAAACCAAGTTGAAGATTTTCAAGTTAACACATATGAAGCTATATCCCAAGCCCGCCCACACGAACTTCTTAGATCGAAAGCTGTCGAAGAAGCTATGGAGCCCGAAGACGATGCCTTTGAAGAGGAAACATCCGAGGAGCCAGCCCCATACAAGTGCAGCATTTGCAAAAAGTCGTACAAGAGACCCAACGCCTACATGCGACACATGGAGGAAGTCCACAAAACCGTACCCAGAGATCTCCCACAAGTGCTATGCAACACTTGTCCCCACTGCGAAAAGCGTTTTACCGCTCCTGCATCTCTTCGGAGACATATAGAAGGGTTTCACAAGCAAGTCAAGCCTTATGTCGCCGAAGCCTCTGATTGCCTGGTCGAAGTAGAGCATATCGCGGAGGAGGACTACATCGAAGAATCGCAGATCATAGAAGAAGGCCAAGTGGAAGACTTCCAGATTGAAACTTATGAAGTAATATCCACAGCGCAGCCAGCAGAACTCCTTAAATCAAAAGCCGCGGAGGAAGCTCTAGAATCCGATGACGATACACATGAAGATGTTTCATCTGAGCATCTCATAGAAGATGAAGAAGAGGGGATTCCAGAGGAGCCAACCATCTACAAGTGCAGCATTTGCAACAAGCCGTACAAGAAACCCAAAGCCTACATGCGTCACATGGAAGAAGTGCACAACACCGTGCCCAAAGATCTTCCACAACTGCTGTGCAACCAGTGCGGATTATGTTTCCCCTCGGCCACTCAGCTGGCCTCCCACTACCGAACCCATTTACCCCCCGCAGTGAAGTCCGATAACTCCTGTCCGCACTGTGAAAAGCGTTTCACCACTCCGGGAACACTGAAGCGGCACATAGAGGGGGTTCACAAGCAGATCAAGCCCTATGTTTGTGACATCTGCGGCAAGAGCTTCAACTATGTCACCGGGCTCAAAGATCACAAGCTGGTCCACACCGAGGAATGTCCCTTCGAGTGTCCCGTGTGCCTGCGACGCTTTAAAAACAAAGCTAGATTAAAGATTCATTCCGATACCCACAGTGCCCAAATCTACGAGTGTGCCATATGCGGCTTGAAGCTCAAGACCCGCCGAACCTTCAACAAGCACAAATTGGTCCACTCAGATGAACGGCAGTACAAATGTGATGTCTGTGGATCGGCATTCAAGCGGAGCAAGACCCTGAAGGCGCATCTCATTCTGCACACTGGCATCCGGCCGTATAAGTGCAACTTCTGCGGCATAGACTTCTCCAACGGCTCCAACTGTCGTTCGCACAAGCGAAAAGCGCATCCCAAGGAACTGGCCGAGGAGGAATCGCGCGGAGTTTCGCGGTCCACGCTACTTCCTATGCTGGATGAACTTACCAAGGCATCCAAGCTTATTAAAACACCCGCTAAGCCGAGCAAAACCAAGGGTAGTAGGCCAAAAGTTCCGCCGAAAGCAGAATCATCCGCAAAGGACACTGATGGAAATGCTATCCTCTACGAACTTGTTGAGGAGCTTGATTACTCCTAG
Protein Sequence: MSSTSAANVATHEDPAIWHKWCRLCSQDHPTNRNVYSREEQPNSWTSMLAMTVGKYFWVDIKKEDELSNYLCSECFTLMDCLMEFSERVRKVQILFNRLQALKPEAVVNYEELREDCGLASDEWKHIMYRAVALPPYKQEELKTNGMEQQVIVIEQEQQQTQEFVQELHIAGEALQTAGMEEEILEDEGEHLAEEEVETMEEEVQQQETSDCLVEVDRIAEEEFIEESRLTENQVEDFQVNTYEAISQARPHELLRSKAVEEAMEPEDDAFEEETSEEPAPYKCSICKKSYKRPNAYMRHMEEVHKTVPRDLPQVLCNTCPHCEKRFTAPASLRRHIEGFHKQVKPYVAEASDCLVEVEHIAEEDYIEESQIIEEGQVEDFQIETYEVISTAQPAELLKSKAAEEALESDDDTHEDVSSEHLIEDEEEGIPEEPTIYKCSICNKPYKKPKAYMRHMEEVHNTVPKDLPQLLCNQCGLCFPSATQLASHYRTHLPPAVKSDNSCPHCEKRFTTPGTLKRHIEGVHKQIKPYVCDICGKSFNYVTGLKDHKLVHTEECPFECPVCLRRFKNKARLKIHSDTHSAQIYECAICGLKLKTRRTFNKHKLVHSDERQYKCDVCGSAFKRSKTLKAHLILHTGIRPYKCNFCGIDFSNGSNCRSHKRKAHPKELAEEESRGVSRSTLLPMLDELTKASKLIKTPAKPSKTKGSRPKVPPKAESSAKDTDGNAILYELVEELDYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602762;
90% Identity: iTF_00486691;
80% Identity: iTF_00486691;