Dsub006340.1
Basic Information
- Insect
- Drosophila subobscura
- Gene Symbol
- lrrfip2
- Assembly
- GCA_008121235.1
- Location
- NC:8962231-8965501[+]
Transcription Factor Domain
- TF Family
- LRRFIP
- Domain
- LRRFIP domain
- PFAM
- PF09738
- TF Group
- Unclassified Structure
- Description
- LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.7e-116 3.5e-112 374.1 22.4 1 299 38 327 38 328 0.96 2 2 0.032 4.2e+02 -0.4 3.7 210 241 347 377 329 401 0.50
Sequence Information
- Coding Sequence
- atgtacatagtacattttaatgaaatgGAAAGCACAAGCGTCACTGGTCGACGACGAAACAATACACGAGTGAATGCAGAGGACAACGCTCTAGATCAAATCACAAAAGAGGCTGAAGCGCGTCTTGCTGCACGTCGTCAGGCACGTGCTGAAGCGCGCGAGATACGTATGAGAGAGCTTGAACGCCAACAAAaggaacaagaacaaaatgcTGACCGGGTATTTGATATGCACAACTCGAGTGCCAGTTTTGGTAGTGACTCGATCTCGGCACATCCTGCACGTCTCGTCTTTGGCGgattaataaatattactcGAAATACGGCATCCCGACGTAGTAGTGAAGATTCTTTGGAGGATGAAGGCAGAAGCTTACGCGACTTCAAGCACGAGCTTAACgATGTCGAAGAACGTTTCCGGAAAGCTATGATAACCAATGCACAGCTAGACAATGATCGTGCATCACAGTCGTACGAAGTCAAATTACTTAAGGACAAATGTGAAACCATGCAAGAGGCATTCGCACAGCTGCAGCGCGAGTTTAAAGAGAAGTCGCGTGACTGCAACGCAATTAAACGAAACTTAGACCGCACCACTGTTGAGCTTAAGCTAGTTCAAGGTCAGCTTAGCGAGCGAGATTCATTGATTGCAGAGCAGGGCCTTGTGATTgttgcaattgaaaatgccGATGGCAGTGATGCCAAGCGAGCTCTAGTCAGTGTTGAAAATGCTAATGTACTGGCTTCCGTTCAGGGTTCTTTAGATGTAAGAATACAAAAGTTTAGCGATGAAAAGCAGCAATTACTATCCGAAGTGcagaagctgcaaaaaataattaaagagtATAAAAGCGAAGGAATTGTTGGAACTGGCTCACCGGGTCCCTTTGGTAAAGACAACGATTATGAGGCTCAAAgagaagcaaacaaaatcatATCAGACTATAAATATAAGCTACAAAAGGCTGAACAAGAAATGGCTAATCTTCAATCGAGCTTAGCCCGTTCAGAGACGCAAGTTATTCGATACAAAAGCACCGCAGAAGCCGCCGaaaaggcagaagcagaattAAAAGTGGAACGCCGTAAGCTACAACGTGAGCACCGTGAAGTTTTGGAAAAACTGGAAGAAACAGAGACAGCTAATAACCATTTATTGAAACGACttgacaaattaaaaaatgcgAAAAGTGCCATTCTTAAGGACCTATGA
- Protein Sequence
- MYIVHFNEMESTSVTGRRRNNTRVNAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKEQEQNADRVFDMHNSSASFGSDSISAHPARLVFGGLINITRNTASRRSSEDSLEDEGRSLRDFKHELNDVEERFRKAMITNAQLDNDRASQSYEVKLLKDKCETMQEAFAQLQREFKEKSRDCNAIKRNLDRTTVELKLVQGQLSERDSLIAEQGLVIVAIENADGSDAKRALVSVENANVLASVQGSLDVRIQKFSDEKQQLLSEVQKLQKIIKEYKSEGIVGTGSPGPFGKDNDYEAQREANKIISDYKYKLQKAEQEMANLQSSLARSETQVIRYKSTAEAAEKAEAELKVERRKLQREHREVLEKLEETETANNHLLKRLDKLKNAKSAILKDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00336724;
- 90% Identity
- iTF_00514877;
- 80% Identity
- -