Basic Information

Insect: Drosophila seguyi
Gene Symbol: -
Assembly: GCA_008042675.1
Location: VNJU01010397.1:1964-6389[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0017 0.12 12.8 1.5 1 23 211 233 211 233 0.96

2 25 2.3 1.6e+02 2.9 3.8 1 21 240 260 240 262 0.84

3 25 0.022 1.6 9.3 0.4 2 23 294 315 293 315 0.95

4 25 0.096 7 7.2 0.5 1 23 386 409 386 409 0.94

5 25 0.52 38 4.9 2.0 1 23 450 472 450 472 0.97

6 25 0.12 8.5 7.0 0.0 2 23 484 505 483 505 0.96

7 25 0.002 0.14 12.5 1.1 1 23 586 609 586 609 0.97

8 25 0.0012 0.085 13.3 1.1 2 22 620 640 619 640 0.94

9 25 0.037 2.7 8.5 4.6 1 23 649 671 649 672 0.95

10 25 0.0024 0.17 12.3 1.5 2 23 691 712 690 712 0.97

11 25 4.5e-06 0.00033 20.9 4.3 1 23 719 741 719 741 0.98

12 25 0.0074 0.54 10.7 0.5 1 23 877 900 877 900 0.91

13 25 0.021 1.5 9.3 0.8 2 22 908 928 907 928 0.93

14 25 0.027 2 9.0 3.3 1 23 937 960 937 960 0.93

15 25 3.5e-05 0.0026 18.1 1.4 2 23 979 1000 978 1000 0.97

16 25 8.4e-05 0.0061 16.9 0.4 1 23 1007 1029 1007 1029 0.98

17 25 0.079 5.8 7.5 0.0 2 21 1056 1075 1055 1076 0.92

18 25 0.03 2.2 8.8 4.8 1 23 1122 1145 1122 1145 0.96

19 25 0.0019 0.14 12.6 1.0 1 23 1182 1205 1182 1205 0.97

20 25 0.00038 0.028 14.8 1.4 1 23 1229 1252 1229 1252 0.97

21 25 4.9e-06 0.00036 20.7 0.2 2 23 1279 1300 1278 1300 0.95

22 25 0.0025 0.18 12.2 2.6 1 23 1306 1328 1306 1328 0.99

23 25 1.9e-06 0.00014 22.0 2.0 1 23 1334 1356 1334 1356 0.97

24 25 1.7e-07 1.2e-05 25.3 2.4 1 23 1362 1384 1362 1384 0.99

25 25 0.00064 0.046 14.1 0.1 1 21 1390 1410 1390 1414 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0017	0.12	12.8	1.5	1	23	211	233	211	233	0.96
2	25	2.3	1.6e+02	2.9	3.8	1	21	240	260	240	262	0.84
3	25	0.022	1.6	9.3	0.4	2	23	294	315	293	315	0.95
4	25	0.096	7	7.2	0.5	1	23	386	409	386	409	0.94
5	25	0.52	38	4.9	2.0	1	23	450	472	450	472	0.97
6	25	0.12	8.5	7.0	0.0	2	23	484	505	483	505	0.96
7	25	0.002	0.14	12.5	1.1	1	23	586	609	586	609	0.97
8	25	0.0012	0.085	13.3	1.1	2	22	620	640	619	640	0.94
9	25	0.037	2.7	8.5	4.6	1	23	649	671	649	672	0.95
10	25	0.0024	0.17	12.3	1.5	2	23	691	712	690	712	0.97
11	25	4.5e-06	0.00033	20.9	4.3	1	23	719	741	719	741	0.98
12	25	0.0074	0.54	10.7	0.5	1	23	877	900	877	900	0.91
13	25	0.021	1.5	9.3	0.8	2	22	908	928	907	928	0.93
14	25	0.027	2	9.0	3.3	1	23	937	960	937	960	0.93
15	25	3.5e-05	0.0026	18.1	1.4	2	23	979	1000	978	1000	0.97
16	25	8.4e-05	0.0061	16.9	0.4	1	23	1007	1029	1007	1029	0.98
17	25	0.079	5.8	7.5	0.0	2	21	1056	1075	1055	1076	0.92
18	25	0.03	2.2	8.8	4.8	1	23	1122	1145	1122	1145	0.96
19	25	0.0019	0.14	12.6	1.0	1	23	1182	1205	1182	1205	0.97
20	25	0.00038	0.028	14.8	1.4	1	23	1229	1252	1229	1252	0.97
21	25	4.9e-06	0.00036	20.7	0.2	2	23	1279	1300	1278	1300	0.95
22	25	0.0025	0.18	12.2	2.6	1	23	1306	1328	1306	1328	0.99
23	25	1.9e-06	0.00014	22.0	2.0	1	23	1334	1356	1334	1356	0.97
24	25	1.7e-07	1.2e-05	25.3	2.4	1	23	1362	1384	1362	1384	0.99
25	25	0.00064	0.046	14.1	0.1	1	21	1390	1410	1390	1414	0.91

Sequence Information

Coding Sequence: ATGCTGCCCTCAAATATTTGCCGCACTTGTGCGGCTCAGAACACGGATTTACGGCCATTGTCCACCTGTCTGGCCAAAGACGCCTCAAAAAGCTTCTATGATGTACTCCAGGAGCTAACGCAAATCGATCCTCTGGTTGAGAGCTCGGGCGACAACCTGCCGCAGCATCTGTGCACCGAATGCCTGGCGAGATTGGAAAGTGCTTATGCCTTTGTAGAGCAGGCCAGAAAAGTCAACGGCGAGCTGTTGGTTCGTCTGCGGGAATGCCTCGATGAAATGCCCATTGACATTCCCCAGGAGCAGCCACACATAAAAACCGAAGTAGATATCGATGAGGCGACTCCCAAGTTTGTTGTGGATGTCGATGCCACCGGAATCTCGTCTGTGGAGTTCAAATGGCGGCCGGAAAGTGACAGCGATAGGGAATCTGCTGGAGCAGCATCCAGTGATGATGAGAATGGTGTCGAGAAGAAGCCCTATTCTCTTAGACGCAGTGCGCGTAAAATCAAGCAGCCTGTAGAGAATAATAATGAGGAGCCAGAGTTGCCAACAGAACCATCGCCCAGCAAACGTCGCCGAGGCCGTCCGCCCGGCCCGGCCAAGTGCCAGTCAATGACCTCCGATGGACGCCATGCCTGCAAGGTGTGCGGAAAGACCTTCTCCTGGTTCCGCGATATGCAACGACATGCTCGCATCCATTGCGAGAAATCCAATTCGTTCGTTTGTGACACCTGCGGCAAGGGGTTTCTACGCAAGGACAAGTACACATTCCACCTGCGCTGCCACGAAAAGCGGGAAGCCAAATCCAAGGCTCTGCAGCTGGGTAACGAGTGGCGCTTCGCTGAACGGCTGTACAGTTCCGGCAGGCTGGAGAGAATCGAGTGCAAGCTGTGTGGCCTAAAGTGTCCCCGAATTCAGGAGCTCAGAATCCACTTGGTCAGCCATCAGAACGTGGAGAGCCTGCTCCAGTTGAGGGAGAACAGCGATGTGATACTGGAGCACTATGCCGACCAGCCAGTGGACTTGGACGGCGTCAAGCAGCTAGTTATCAAGGACCTAACGGCGGGGCACTTGGAAAAGTTTGCTTCCGTGGTGAATTTCCACGGATACGAGTTGGGATTGTATGACTCGGACGAGGAATCTGCTAGCGGAGAGTATGAGTGCACGGCGTGCAATCTTTCTTTAGCGAGGAAACATCAAGTGGTGAGGCACACCCTGGAGGAGCACGCTCAATCCTCCCCTTCTGAGCTTCCCTGGCAACGCTGCGGCAACTGTAAAATTGGATTCCTTTGCTCCAGACTCTACGATTGCCATGTGAATACCCAGTGTGAAAGCAAATTGAAGCGATATCGGTGCGCAAAGTGCCCGGGGAAGTTTATGTGGCCGGAGAACCTGCACAGGCACGCCTGCTCCCATCGCCACCAGGAAGCGACGCGTGCCCGCAAGATCTCCTGCTCCTTGTGCGATGAACTCCTGCCCACGTTGGCCCAATTGCGTATACACTTGGTTACCCACCAGAGGAACATGAGTGGCATCGATCCGGAGCACAGTTCCACGTTTTTTCGGTCGTTCTATCCCAACGGACTGGACTGCACGCCGGAGGAGTTAGGTGTCCGCATATCCGAGGACTTCGAGGTGCAGGACTTTGATCGCTACTACAACGCCTGCACGGGCAGTGGCCAAGAGCTGGATCTCTTTGATTCCGAGACGGAGCAGAGCGGAGACGATCGCGAGGAGGACGAGAAGCCGACCTGCCACACCTGTTTGCTGTGCGGAGAGGTGACAAAGAGACTCACGACCCTGCTGCAGCACCAAAACAGAGCCCATTCAAAGGCGACAACGAAAGATTTGCCTTGTTCCTGCCACGACTGTGGTGCTAGTTTCATAAGTGATGCCCTGCTGCAACAGCACCGCCGGCGTATCTGCGCCAAGAAACATTTCCGTCATCACTGCCCGACCTGCAATCTCCGCTTCATCTGGCCAAGCAACTATGAGCTGCATCTGAAGACCCACCATAGCCACTTGGAGGAAGACCAACTCGAGGAGGGTGAGCAGCGGGACGCAAAGCTGCAGTGCGACGAGTGCGAAAAGGTCTTCATCTGGCACAAGGATCTCACGCGTCACAAGCGCTTGCACCTGCCGCAGTCGGCGCAGTTCGAGTGTCCGCATTGCGACCGAAAGTTCCACCGCAAGGATGGCCTCAAGTCCCACTTGCGGGTCCATACCGAGGAACAGCTGGTGGAGCAGCCTCTCACATCCGACAGCAGTGAGGTTCTTGCCCTGCTCTCCCGTCCCCATGGCTGCAAGCAGATCCAATGCATGATCTGTCTCTCGCGCCACTCCAAGATCTCTGATCTGCGAACTCACCTGGGCGCCCATCAATACGGATTGAGCTTTTCCACAGAGACCGATATTTCCAGTGTCTCAAAGTCGCTGTATCCGGAGGTGGGAACGGCCTTGGGCAGAGATGAACTGGCGGAACGAATTATGGCAGATATCGACCAAGGCGTGGATCTGGATCGATTTATTTCCATCACTAATGAGGCTGGGCTGGAGCTCAACTTGGACAGCAGCGAAACGGACACTGAATCCGAGAAAGATGAGGAGGATGACCCGTCCAGACAGAACTACGCCTGCAATCTCTGTCCCACGGAGGTAAGGAGAAAGCATCAGCTTTATGCCCACCAAGGGGAAAGTCATCAGTGGGAAGAGGCTGCACTCGTTTGCTCGCACTGCCAGGCTAGGTTCGTCAGCGAATCCCTGCTAGATCATCACTCCAGGACCTTCTGCGGCAATGTCCAGAAGCGCTTCCAGTGCCGCAAATGCCCGCTTCGCTTTCGCTGGCGTGAGAACCTGAAGCACCACCTATATTTGTCCCATCAACAGGCTGAGATGCCAGCTGCAGAGGATTCTTCGCAGGCGGACGCCGAACTGCAATGTGGCGAGTGCCAGCGAACGTTTAAGATGCAAAAAGATCTCACACGGCACACCTTGATGCACGCCCGGGAGGCGACGATCTATCGGTGCCGCTGGTGTGCTCGTCGATTCTACCGCTGGGCCAATCTTCTACAGCACATCGCACGCCACGGCATCCGGGCTAGTGAGTTGCACTATGCCGAGGCTCTCCTCGACTTCTATGGACATCCAGGCGGTCAGAAAACCGTGGAATGCCGGGTGTGCAATGTCAGCTTCGCCAGTATCGCCGCCCTGCGTCTGCATCTGGAAACCATGCCGGAGGGGAGCCACCATGAGATCTCCTCGTTGAAAAACTACTCGATTACCAACCAAATGGGCTTCGAGCTGGAGCTCCAGGACTCGGAAACGGATGAGGACCAGTCAAAGCCGCCCGGTGTGCCTGCCTACTACACGTGCAGCATGTGCCAGTTGAGGTGTGTACGGAAATTCGAGctgcaccagcaccagcaggcCATGCATCGGCTGGAGAAGATTCCCGACGGTTGCGATCAGTGCATCTTCAAGAGCGTCTGTCCCGATCTCATTGCCCATCACAAGAGGACGCAGTGCGATAACCGGGAGAAGCAGTTCACGTGTTCCCGCTGCGGCTATAAATTCATGTGGGAGTCTAACCTGCTGACGCACATGCAGATGCAGCACGGGAAGGCGGACGAACCGGAGCAGGAGGGAGGCAAGGAGGCAGAAGAACCGAAGGCCGGGAGCCCGGTTTTCCAGTGTGCCCTGTGTCCCAGGAAGTACAACCGAAAGGACCGCCTTACGGCACACGTGAAAAAGTTTCATGGGCCCGACGGCAAGGGCCCTGAGGTGGTAAAGGTTCCCCCTACGAGAGCCACCTCACCCAAGGAACCGAAACGTTTCCTGTGCGCATTCTGCGGCAAGGCGGtcagctcctcctccaacCTGATCATCCACATGCGCCGTCACACGGGCGAAAAGCCCTTCAAGTGCGAGTTCTGCGCCATGGCCTTCCCACGATCCTCAGACCTTCAGTGCCACCGGCGGACTCACACAGGAGAGCGCCCCCATGTGTGTACCGTGTGCCAGAAGGGATTCGCCCGCTcctacaagctgcagcagcacatGCGCATCCACAGCGGCGAGCGACCGTACAAGTGCACCTACTGCGAGAAGAGCTTCACCCAGTCCAACGACCTGACACTCCACATCCGGCGGCACACAGGCGAGCGGCCTTACCAGTGCGGCATCTGCGGGGAACGTTTCATTCAGGGAACGGCTTTGAAAAATCATCGCCTGCAGCAGGGACACTTCGAGGAGGGTCAGAATTCTGGGGAGCCAGCAAGGCGCACGGTTTTGGAACAGTTTACTGTATGA
Protein Sequence: MLPSNICRTCAAQNTDLRPLSTCLAKDASKSFYDVLQELTQIDPLVESSGDNLPQHLCTECLARLESAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEQPHIKTEVDIDEATPKFVVDVDATGISSVEFKWRPESDSDRESAGAASSDDENGVEKKPYSLRRSARKIKQPVENNNEEPELPTEPSPSKRRRGRPPGPAKCQSMTSDGRHACKVCGKTFSWFRDMQRHARIHCEKSNSFVCDTCGKGFLRKDKYTFHLRCHEKREAKSKALQLGNEWRFAERLYSSGRLERIECKLCGLKCPRIQELRIHLVSHQNVESLLQLRENSDVILEHYADQPVDLDGVKQLVIKDLTAGHLEKFASVVNFHGYELGLYDSDEESASGEYECTACNLSLARKHQVVRHTLEEHAQSSPSELPWQRCGNCKIGFLCSRLYDCHVNTQCESKLKRYRCAKCPGKFMWPENLHRHACSHRHQEATRARKISCSLCDELLPTLAQLRIHLVTHQRNMSGIDPEHSSTFFRSFYPNGLDCTPEELGVRISEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDDREEDEKPTCHTCLLCGEVTKRLTTLLQHQNRAHSKATTKDLPCSCHDCGASFISDALLQQHRRRICAKKHFRHHCPTCNLRFIWPSNYELHLKTHHSHLEEDQLEEGEQRDAKLQCDECEKVFIWHKDLTRHKRLHLPQSAQFECPHCDRKFHRKDGLKSHLRVHTEEQLVEQPLTSDSSEVLALLSRPHGCKQIQCMICLSRHSKISDLRTHLGAHQYGLSFSTETDISSVSKSLYPEVGTALGRDELAERIMADIDQGVDLDRFISITNEAGLELNLDSSETDTESEKDEEDDPSRQNYACNLCPTEVRRKHQLYAHQGESHQWEEAALVCSHCQARFVSESLLDHHSRTFCGNVQKRFQCRKCPLRFRWRENLKHHLYLSHQQAEMPAAEDSSQADAELQCGECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHIARHGIRASELHYAEALLDFYGHPGGQKTVECRVCNVSFASIAALRLHLETMPEGSHHEISSLKNYSITNQMGFELELQDSETDEDQSKPPGVPAYYTCSMCQLRCVRKFELHQHQQAMHRLEKIPDGCDQCIFKSVCPDLIAHHKRTQCDNREKQFTCSRCGYKFMWESNLLTHMQMQHGKADEPEQEGGKEAEEPKAGSPVFQCALCPRKYNRKDRLTAHVKKFHGPDGKGPEVVKVPPTRATSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRLQQGHFEEGQNSGEPARRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00613615; iTF_00561899; iTF_00485271; iTF_00524536; iTF_00490202;
80% Identity: -