Basic Information

Insect: Drosophila jambulina
Gene Symbol: ZNF296
Assembly: GCA_018152175.1
Location: JAECXH010000012.1:29066702-29071121[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0014 0.1 13.0 1.4 1 23 210 232 210 232 0.96

2 25 2.3 1.6e+02 2.9 3.8 1 21 239 259 239 261 0.84

3 25 0.025 1.8 9.1 0.4 2 23 293 314 292 314 0.95

4 25 0.022 1.6 9.3 1.1 1 23 387 410 387 410 0.94

5 25 0.075 5.4 7.6 0.7 1 23 451 473 451 473 0.98

6 25 0.013 0.97 9.9 0.1 2 23 485 506 484 506 0.96

7 25 0.003 0.22 12.0 1.1 1 23 587 610 587 610 0.97

8 25 0.0011 0.083 13.3 1.2 2 22 621 641 620 641 0.94

9 25 5.4 3.9e+02 1.7 5.8 1 23 650 672 650 673 0.92

10 25 0.0024 0.17 12.3 1.5 2 23 692 713 691 713 0.97

11 25 4.5e-06 0.00033 20.9 4.3 1 23 720 742 720 742 0.98

12 25 0.0033 0.24 11.8 1.6 1 23 877 900 877 900 0.95

13 25 0.021 1.5 9.3 0.8 2 22 908 928 907 928 0.93

14 25 0.027 2 9.0 3.3 1 23 937 960 937 960 0.93

15 25 3.5e-05 0.0025 18.1 1.4 2 23 979 1000 978 1000 0.97

16 25 5e-05 0.0036 17.6 0.4 1 23 1007 1029 1007 1029 0.98

17 25 0.027 2 8.9 0.0 2 21 1056 1075 1055 1076 0.93

18 25 0.034 2.4 8.7 4.0 1 23 1122 1145 1122 1145 0.96

19 25 0.0021 0.15 12.5 0.9 1 23 1182 1205 1182 1205 0.97

20 25 0.00038 0.028 14.8 1.4 1 23 1229 1252 1229 1252 0.97

21 25 4.9e-06 0.00036 20.7 0.2 2 23 1279 1300 1278 1300 0.95

22 25 0.0026 0.19 12.2 2.6 1 23 1306 1328 1306 1328 0.99

23 25 1.9e-06 0.00014 22.0 2.0 1 23 1334 1356 1334 1356 0.97

24 25 1.7e-07 1.2e-05 25.3 2.4 1 23 1362 1384 1362 1384 0.99

25 25 0.0011 0.083 13.3 0.1 1 21 1390 1410 1390 1414 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0014	0.1	13.0	1.4	1	23	210	232	210	232	0.96
2	25	2.3	1.6e+02	2.9	3.8	1	21	239	259	239	261	0.84
3	25	0.025	1.8	9.1	0.4	2	23	293	314	292	314	0.95
4	25	0.022	1.6	9.3	1.1	1	23	387	410	387	410	0.94
5	25	0.075	5.4	7.6	0.7	1	23	451	473	451	473	0.98
6	25	0.013	0.97	9.9	0.1	2	23	485	506	484	506	0.96
7	25	0.003	0.22	12.0	1.1	1	23	587	610	587	610	0.97
8	25	0.0011	0.083	13.3	1.2	2	22	621	641	620	641	0.94
9	25	5.4	3.9e+02	1.7	5.8	1	23	650	672	650	673	0.92
10	25	0.0024	0.17	12.3	1.5	2	23	692	713	691	713	0.97
11	25	4.5e-06	0.00033	20.9	4.3	1	23	720	742	720	742	0.98
12	25	0.0033	0.24	11.8	1.6	1	23	877	900	877	900	0.95
13	25	0.021	1.5	9.3	0.8	2	22	908	928	907	928	0.93
14	25	0.027	2	9.0	3.3	1	23	937	960	937	960	0.93
15	25	3.5e-05	0.0025	18.1	1.4	2	23	979	1000	978	1000	0.97
16	25	5e-05	0.0036	17.6	0.4	1	23	1007	1029	1007	1029	0.98
17	25	0.027	2	8.9	0.0	2	21	1056	1075	1055	1076	0.93
18	25	0.034	2.4	8.7	4.0	1	23	1122	1145	1122	1145	0.96
19	25	0.0021	0.15	12.5	0.9	1	23	1182	1205	1182	1205	0.97
20	25	0.00038	0.028	14.8	1.4	1	23	1229	1252	1229	1252	0.97
21	25	4.9e-06	0.00036	20.7	0.2	2	23	1279	1300	1278	1300	0.95
22	25	0.0026	0.19	12.2	2.6	1	23	1306	1328	1306	1328	0.99
23	25	1.9e-06	0.00014	22.0	2.0	1	23	1334	1356	1334	1356	0.97
24	25	1.7e-07	1.2e-05	25.3	2.4	1	23	1362	1384	1362	1384	0.99
25	25	0.0011	0.083	13.3	0.1	1	21	1390	1410	1390	1414	0.91

Sequence Information

Coding Sequence: ATGCTTCCCTCAAATATTTGCCGCACTTGTGCGGTTCAGAACGCGGATTTGAGGCCATTGTCCACCTGTCTGGCCAAAGACGCCTCAAAAAGTTTCTATGATGTACTCCAGGAGCTAACGCAAATCGATCCCCTGGTTGAGGGCTCGGGTGACTATCTGCCGCAGCATCTGTGCACCGAATGCCTGGCGAGATTGGAAAGTGCCTACGCCTTTGTGGAACAGGCCAGAAAAGTCAACGGCGAGCTGTTGGTTCGTCTGCGAGAATGCCTCGATGAAGTCCCCATAGATATTCCCCAGGAGCAGCCACTCATCAAAACCGAAATAGATATCGATGAGGCGACTGCCAAGTTTGCTGTGGATGTAGATTCCACCGGAATTTCGTCTGTGGTGTTAAAATGGCAGCCGGAAAGTGACAGCGATAGGGATTCTGCTGGAGCAGCATCCAGTGATGAGAATGATGTCGAGCAGAAGCCCTATTCTCTAAGACGCAGTGCGCGTAAAAACAAGCAACCTGCAGAGAATGGTAATGAGGAGCCAGATTTGCCAACAGAACCATCGCCCAGCAAACGTCGTCGAGGCCGTCCGCCCGGCCCGGCCAAGCGTCAGTCGATGACCTCCGATGGACGCCACGCCTGTAAGGTGTGCGGAAAGTCCTTCTCCTGGTTCCGTGATATGCAACGCCATGCTCGCATCCATTTCGAAAAATCCGACGCGTTCGTTTGTGATACCTGCGGCAAGGGGTTCTTACGCAAGGACAAATACACATTCCACCTGCGCTGCCATGAAAAGCGTGAAGCCAAACGCAAGGCTCTGCAGCTAGGTAACGAGTGGCGCTTCGCCGAGCGGCTGTACAGTTCCGGCAGGCTGAAGAGAATCGAGTGCAAGCTGTGTGGCTTAAAGTGTCCCCGAATTCAGGAGCTCAGAATTCACTTGGGCAGCCATCAGAACGAGGAGAGCCTGCTCCAGTTGAGGGAAAACAGCGATGTGATAAAGGAACACTACGCCGACCAGCCAGGCGACTTGGACGGCATCAAGCAGCAAATTATTAGAGACATAACGGCGGGGCATTTGGAAAAGTTTGCTTCTGTGGTGAATTTTCATGGCTACGAGTTGGGATTGTATGACTCGGACGAGGAATCTGTTAGCGGAGAGTCCAAATATGAGTGCACGGCTTGCAATTTTCCCTTTGGGAGGAAACATCAAATGGTGAGGCATACGCTGGAGGAGCACGCTCAATCCCCCCCTTCAGAGCTTCCCTGGCAACGCTGCAGCTGCTGTAAAATTGGATTCCTCTGCTCCAGACTCTACGATTGCCATGTGAGTACCCAGTGTGACAGCAAACTAAAGGGGTATCGGTGCGCAAAGTGCCCTGGGAAGTTTATGTGGCCGGAGAATCTACAGAGGCATGCCTGCTCCCATCGCCACCAGGAAGCGACGTCTGCCCGCCAGATCACCTGCTCCTTGTGCGATGAATTCCTGCCCACATTGGCCCAATTGCGGATACACTTGGTAACCCACCAGAGAAACATGAATGGCATCGATCCGAAGCACAGTTCCACGTTCTTTCGATCGTTTTATCCCAACGGACTGGACTGCACCGCGGAGGAGTTGGGTGTTCGTATAGCCGAGGACTTTGAGGTGCAGGACTTTGATCGCTACTACAACGCCTGCACTGGCAGTGGCCAAGAGCTGGATCTCTTTGATTCCGAGACGGAGCAGAGCGGGGACGATCGGGAGGAGGACGAAAAGCCCACCTGCCACACCTGTTTGCTCTGTGGAGAGGTGACAAACAGACTCACGACCCTGCTGCAGCATCAGAAAAGAGCCCATTCAAAAGCGACGACGAAAGATTTGCCTTGTTCCTGCCACGACTGTGGTGCTAGCTTCATAAGTGATGGCCTGCTACAACAGCACCGCCGGCGTGTTTGCGCCAAGAAACATTTCCGTCATTGCTGCCTGAGCTGCAATCTCCGATTCATCTGGCCGAACAACTACGAGCAGCATCTGAAGACCCACCATACCCACTTGGAGGAAGACCAACTCGAAGAGGGTGAGCATCGTGACGCAAAGCTCCAGTGCGACGAGTGCGAAAAGGTCTTCATCTGGCACAAGGATCTGACGCGTCACAAGCGCTTGCACTTGCCGCAGTCGGCGCAGTTCGAGTGTCCGCATTGCGACCGAAAGTTCCACCGCAAGGATGGCCTCAAGTCCCACTTGAGGGTCCATACAGAGGAACAGCTGGTAGAGCAGCCTCTCACATCCGACAGCTGTGAGGTTCTTGCCCTGCTCTCCCGCCCTCATGGCTGCAAGCAGATCCAATGCATGATCTGTCTCTCACGCCACTCTAAGATCTCTGACCTGCGAACCCACCTGGGCGCCCATCAATACGGATTGTGCTTTTCCACAGAGACCGATATTTCCAGTATCTCAAAGTCGCTGTATCCGGAAGTGGGAACCGCCTTGGGCAGAGATGAACTGGCGGAGAGAATTATGGCAGATATAGAACAAGGAGTGGAGCTAGATCGATTTATTTCCATCACCAATGAGGCTGGGTTGGAGCTTAACTTGGACAGCAGCGAAACGGACACTGAATCCGAAGAAGAGGAGGAAGACCCGTCCAGTCAGAGCTACTCTTGCAATCTCTGTCCGACGGAGGTAAAGAGAAAGCATCAGCTTTATGCACACCAAGGGAAAAGTCATCAGTGGGAGGAGGCACCGCTCGTTTGCTCGCACTGCCAGGCTAGGTTTGTCAGCGAATCCCTACTGGATCATCACTCCAGGACCTACTGCGGTAATGTCCAGAAGCGCTTCCAGTGCCGCAAATGCCCGCTTCGCTTCCGCTGGCGTGAGAACCTGAAACACCACCTATATTTGTCCCATCAGCAGGCTGAGATACCAACTGCAGAGGATTCTTTGCCAGCAGATGCCGAACTACAATGTGGGGAGTGCCAGCGAACGTTCAAGATGCAAAAGGATCTCACACGGCACACCTTGATGCACGCCCGGGAGGCGACGATCTATCGGTGCCGCTGGTGTGCTCGTCGATTCTACCGCTGGGCCAATCTCATACAGCACATCGCACGCCACGGTATCCGGGCTAGTGAGTTGCCCTATGCCGAGGCTCTCCTTGACTCCTATGGACATCCAGGCGGTCAGAAAACCGTGGAATGCCGGGTGTGCAATGTCAGCTTCTCCAGTATCGCCGCCCTGCGTCTGCATCTGGAAACCATGCCGGCAGGAAGCCACCATGAGCTATCCTCGTTGAAGAACTACTCGATCACCAACCAAATGGGCTTCGAGCTGGAGCTCCAGGACTCGGAAACGGATGAGGAGCAGTCAAAACCGCCGGGTGTGCCCGCCTACTACACGTGCGGCATGTGCCAGTTGAGGTGTGTACGGAAATTTGAGCTGCACCAGCACCAACAGGCCATGCATCGGCTGGAGAAGATTCCCGATGGCTGCGATCAGTGCATCTTCAAGAGCGTCTGTCCCGATCTCATTAGCCATCACAAGAGGACGCAGTGCGGTAACCGGGAGAAGCAGTTTACGTGCTCTCGCTGCGGCTACAAGTTCATGTGGGAGTCAAACCTGCTTTCACACATGCAGATGCAGCACGGAAAGGCGGACGATCCAGAGCAGGAGGAGGGCAAGGGGGCAGAAGAGCCTAAGGTTGAGAGCCCGGTTTTCCAGTGTGCCCTGTGCCCTAGGAAGTACAACCGAAAGGACCGGCTTACAGCACACGTGAAAAAGTTCCATGGGCCCGGTGGCAAGGGCCCGGAGGTGGAAAAGGTTCCCCCTACCAGAGCCGCCTCCCCCAAGGAACCGAAACGTTTCTTATGCGCATTCTGCGGCAAGGCCGTCAGCTCCTCCTCCAACCTGATCATCCATATGCGCCGCCACACGGGCGAAAAGCCTTTCAAGTGCGACTTCTGCGCAATGGCCTTCCCACGATCCTCAGACCTTCAGTGCCACCGGCGGACTCATACAGGAGAGCGGCCGCATGTTTGTACCGTGTGCCAGAAGGGATTCGCCCGCTCCTACAAGCTGCAGCAGCACATGCGCATCCACAGCGGCGAGCGGCCGTACAAGTGCACCTACTGCGAGAAAAGCTTCACTCAGTCCAACGACCTGACACTCCACATTCGTCGGCACACGGGCGAGCGGCCTTACCAGTGTGGCGTCTGCGGGGAACGGTTCATCCAGGGGACGGCGTTGAAAAATCATCGCCTGCAACAGGGACACTTCGAGGAGGGTCAGAATTCTGGGGAGCCAGCAAGACGCACGGTTTTGGAACAGTTTAATGTATGA
Protein Sequence: MLPSNICRTCAVQNADLRPLSTCLAKDASKSFYDVLQELTQIDPLVEGSGDYLPQHLCTECLARLESAYAFVEQARKVNGELLVRLRECLDEVPIDIPQEQPLIKTEIDIDEATAKFAVDVDSTGISSVVLKWQPESDSDRDSAGAASSDENDVEQKPYSLRRSARKNKQPAENGNEEPDLPTEPSPSKRRRGRPPGPAKRQSMTSDGRHACKVCGKSFSWFRDMQRHARIHFEKSDAFVCDTCGKGFLRKDKYTFHLRCHEKREAKRKALQLGNEWRFAERLYSSGRLKRIECKLCGLKCPRIQELRIHLGSHQNEESLLQLRENSDVIKEHYADQPGDLDGIKQQIIRDITAGHLEKFASVVNFHGYELGLYDSDEESVSGESKYECTACNFPFGRKHQMVRHTLEEHAQSPPSELPWQRCSCCKIGFLCSRLYDCHVSTQCDSKLKGYRCAKCPGKFMWPENLQRHACSHRHQEATSARQITCSLCDEFLPTLAQLRIHLVTHQRNMNGIDPKHSSTFFRSFYPNGLDCTAEELGVRIAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDDREEDEKPTCHTCLLCGEVTNRLTTLLQHQKRAHSKATTKDLPCSCHDCGASFISDGLLQQHRRRVCAKKHFRHCCLSCNLRFIWPNNYEQHLKTHHTHLEEDQLEEGEHRDAKLQCDECEKVFIWHKDLTRHKRLHLPQSAQFECPHCDRKFHRKDGLKSHLRVHTEEQLVEQPLTSDSCEVLALLSRPHGCKQIQCMICLSRHSKISDLRTHLGAHQYGLCFSTETDISSISKSLYPEVGTALGRDELAERIMADIEQGVELDRFISITNEAGLELNLDSSETDTESEEEEEDPSSQSYSCNLCPTEVKRKHQLYAHQGKSHQWEEAPLVCSHCQARFVSESLLDHHSRTYCGNVQKRFQCRKCPLRFRWRENLKHHLYLSHQQAEIPTAEDSLPADAELQCGECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLIQHIARHGIRASELPYAEALLDSYGHPGGQKTVECRVCNVSFSSIAALRLHLETMPAGSHHELSSLKNYSITNQMGFELELQDSETDEEQSKPPGVPAYYTCGMCQLRCVRKFELHQHQQAMHRLEKIPDGCDQCIFKSVCPDLISHHKRTQCGNREKQFTCSRCGYKFMWESNLLSHMQMQHGKADDPEQEEGKGAEEPKVESPVFQCALCPRKYNRKDRLTAHVKKFHGPGGKGPEVEKVPPTRAASPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHFEEGQNSGEPARRTVLEQFNV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00593959;
80% Identity: -