Basic Information

Insect: Drosophila bocqueti
Gene Symbol: ZNF296
Assembly: GCA_018151655.1
Location: JAECXF010000001.1:13745476-13749902[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0016 0.12 12.8 1.5 1 23 210 232 210 232 0.96

2 23 2.2 1.7e+02 2.9 3.8 1 21 239 259 239 261 0.84

3 23 0.0084 0.64 10.6 0.3 2 23 293 314 292 314 0.96

4 23 0.094 7.1 7.3 0.5 1 23 387 410 387 410 0.94

5 23 0.001 0.077 13.4 0.8 1 23 563 586 563 586 0.97

6 23 0.0011 0.087 13.3 1.1 2 22 597 617 596 617 0.94

7 23 0.1 7.8 7.1 4.4 1 23 626 648 626 649 0.94

8 23 0.0023 0.18 12.3 1.5 2 23 669 690 668 690 0.97

9 23 2.3e-05 0.0017 18.6 5.6 1 23 697 719 697 719 0.98

10 23 0.0023 0.17 12.3 0.9 1 23 854 877 854 877 0.94

11 23 0.02 1.5 9.4 0.8 2 22 885 905 884 905 0.93

12 23 0.026 2 9.0 3.3 1 23 914 937 914 937 0.93

13 23 3.4e-05 0.0026 18.1 1.4 2 23 956 977 955 977 0.97

14 23 8.2e-05 0.0062 16.9 0.4 1 23 984 1006 984 1006 0.98

15 23 0.077 5.9 7.5 0.0 2 21 1033 1052 1032 1053 0.92

16 23 0.033 2.5 8.7 4.0 1 23 1099 1122 1099 1122 0.96

17 23 0.0019 0.14 12.6 1.0 1 23 1159 1182 1159 1182 0.97

18 23 0.00037 0.028 14.8 1.4 1 23 1207 1230 1207 1230 0.97

19 23 4.8e-06 0.00036 20.8 0.2 2 23 1257 1278 1256 1278 0.95

20 23 0.0024 0.19 12.2 2.6 1 23 1284 1306 1284 1306 0.99

21 23 1.9e-06 0.00014 22.0 2.0 1 23 1312 1334 1312 1334 0.97

22 23 1.7e-07 1.3e-05 25.4 2.4 1 23 1340 1362 1340 1362 0.99

23 23 0.00062 0.047 14.1 0.1 1 21 1368 1388 1368 1392 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0016	0.12	12.8	1.5	1	23	210	232	210	232	0.96
2	23	2.2	1.7e+02	2.9	3.8	1	21	239	259	239	261	0.84
3	23	0.0084	0.64	10.6	0.3	2	23	293	314	292	314	0.96
4	23	0.094	7.1	7.3	0.5	1	23	387	410	387	410	0.94
5	23	0.001	0.077	13.4	0.8	1	23	563	586	563	586	0.97
6	23	0.0011	0.087	13.3	1.1	2	22	597	617	596	617	0.94
7	23	0.1	7.8	7.1	4.4	1	23	626	648	626	649	0.94
8	23	0.0023	0.18	12.3	1.5	2	23	669	690	668	690	0.97
9	23	2.3e-05	0.0017	18.6	5.6	1	23	697	719	697	719	0.98
10	23	0.0023	0.17	12.3	0.9	1	23	854	877	854	877	0.94
11	23	0.02	1.5	9.4	0.8	2	22	885	905	884	905	0.93
12	23	0.026	2	9.0	3.3	1	23	914	937	914	937	0.93
13	23	3.4e-05	0.0026	18.1	1.4	2	23	956	977	955	977	0.97
14	23	8.2e-05	0.0062	16.9	0.4	1	23	984	1006	984	1006	0.98
15	23	0.077	5.9	7.5	0.0	2	21	1033	1052	1032	1053	0.92
16	23	0.033	2.5	8.7	4.0	1	23	1099	1122	1099	1122	0.96
17	23	0.0019	0.14	12.6	1.0	1	23	1159	1182	1159	1182	0.97
18	23	0.00037	0.028	14.8	1.4	1	23	1207	1230	1207	1230	0.97
19	23	4.8e-06	0.00036	20.8	0.2	2	23	1257	1278	1256	1278	0.95
20	23	0.0024	0.19	12.2	2.6	1	23	1284	1306	1284	1306	0.99
21	23	1.9e-06	0.00014	22.0	2.0	1	23	1312	1334	1312	1334	0.97
22	23	1.7e-07	1.3e-05	25.4	2.4	1	23	1340	1362	1340	1362	0.99
23	23	0.00062	0.047	14.1	0.1	1	21	1368	1388	1368	1392	0.91

Sequence Information

Coding Sequence: ATGCTTCCCTCAAATATTTGCCGCACTTGTGCGGTTCAGAACACGGATTTGCGGCCATTGTCCACCTGTCTGGCCAAAGACGCCTCAAAGAGTTGCTATGATGTACTCCAGGAGCTTACGCAAATTGATCCCCTGGTTGAGAGCTCGGGTGACAATTTGCCGCAGCATCTGTGCGCCGAATGCCTGGCGAGATTGGAGAGTGCCTACGCCTTTGTAGAACAGGCCAGAAAAGTGAACGGCGAGCTGTTGGTTCGTCTGCGAGAATGCCTCGAGGAAGTGCCCATTGACATTCCTCAGGAGCAGCCACACATCAAAACCGAAGTAGACATCGATGAGGCGACTCCCAAGTTTGTTGTGGATGTAGACTCCACCGGAATATCGTCTGTGGAGTTCAAGTGGCAGCCGGAAAGTGACAGCGATAGGGAATCCGCTGGAGTAGTATCCAGTGACGAGAATGATGTCGAGAAGAAGCCCTATACCTTAAGACGCAGTGCGCGTAAAATCAAGCAGCCGGTAGAGAATAATAATGAGGAGCCAGAGTTGCCAGCAGAACCATCGCCCAACAAACGTCGCCGCGGCCGTCCGCCCGGCCCGGCCAAGTGCCAGTCGATGACCTCCGATGGACGCCACGCCTGCAAGGTGTGCGGGAAGACCTTCTCCTGGTTCCGCGATATGCAACGCCATGCCCGCATCCATTTCGAGAAATCCAAGGCGTTCGTTTGTGACACCTGCGGCAAGGGGTTCCTACGCAAGGACAAGTACACATTCCACCTGCGATGCCACGAAAAGCGGGAAGCCAAATGCAAGGCTTTGCAGCTCGGTAACGAGTGGCGCTTCGCCGAACGCCTGTACAGTTCCGGCAGGCTGAAGAGAATCGAGTGCAAGCTGTGTGGCCTAAAGTGTCCCCGAATCCAGGACCTCAGAGTTCACTTGGCCAGCCATCAGAACGTGGAGGGCCTGCTCCAGTTGAGGGAGAACAGCGATGTGATAAAGGAGCACTATGCCGACCAGCCAGGCGACTTGGACGGCGTCAAGCAGCGAATTATCAAGGATCTAACGGAGGGGCACTTGCAAAAGTTTGCTTCCGTGGTGAATTTCCACGGTTACGAGTTGGGATTGTATGATTCGGACGAGGAATCTGCTAGCGGAGAGTCCAAATATGAGTGCACGGCGTGCAATCTTTCCTTGGCGAGAAAACATCAAGTGGTGAGGCACACGCTGGAGGAGCACGCCCAATCCTCCCCTTCAGAGCTTCCCTGGCAGCGCTGCGGCTCCTGTAAAATTGGATTCCTCTGCTCCAGACTCTACTACTCCCACGTGAACACCCAGTGTGACAGCAAACTGAAGCGGTATCGGAAGCGACGTCTGTCCGCCAGATCTCCTGCACCTTGTGCGACGAATTCCCTGCCCACATTGGCCCAATTACGGATACACTTGGTTACCCACCAGAGTAACATGAGTGGCATCGATCCGGAGCACAGTTCCACATTCTTTCGGTCGTTCCATCCCAACGGCCTGGACAGCACCCCGGAGGAGTTGGGTGTCCGCATAGCCGAGGACTTCGAGGTGCAGGACTTTGATCGCTACTACAACGCCTGCACGGGCAGTGGCCAAGAGCTGGATCTCTTTGATTCCGAGACGGAGCAGAGCGGGGACGATCGGAATGAGGACGAGAAGCCGACCTGCCACACATGTTTGCTGTGCGGAGAGGTGACGAGCAGACTGACGTCCCTGCTGCAGCACCAGAACAGAGCCCATTCGAAGGCGACGACAAAAGATTTGCCTTGCTCCTGCCACGACTGTGGTGCTAGCTTCATAAGTGATGCCCTGCTGCAACAGCACCGCCGGCGTATCTGCGCCAAGAAACATTTCCGTCACCACTGCCCGAGCTGCAATCTGCGATTCATCTGGCCGAGCAACTATGAGCTGCACCTGAAGACCCACCACAGCCACTTGGAGGAAGACCAACTCGAGGAGGGTGGTGAGCATCGGGACGCGAAGCTGCAGTGTGACGAGTGCGAAAAGGTCTTCATCTGGCACAAGGATCTGACGCGTCACAAGCGCTTGCACCTGCCGCAGTCGGCGCAGTTCGAGTGTACGCACTGCGACCGAAAGTTCCACCGCAAGGATGGCCTCAAGTCCCACCTGCGGGTCCATACAGAGGCACAGCTGGTGGAGCAGCCTCTCACATCCGACAGCAGTGGGGTTCTTGCCCTGCTCTCCCGTCCCCATGGCTGCAAGCAAATCCAATGCATGATCTGTCTCTCACGCCACTCCAAGATCTCTGATCTGCGAACCCACCTGGGCGCCCATCGATACGGATTAAGCTTCACCACAGAGACCGATATTTCCAGTATCTCAAAGTCTCTGTATCCGGAAGTGGAAGCGGCCTTGGGCACAGATGAGCTGGCGGAGAGAATTATGGCAGATATCGGCCAAGGAGTGGAGCTGGATCGTTTCATTTCCATCACCAATGAGGCTGGGTTGGAGCTCAACTTGGACAGCAGCGAAACGGACACTGAATCCGAGGAAGAGGAGGAGGGCCCGTCCAGTCAGAACTACGCCTGCAATCTCTGTCCCACCGAGGTAAAGAGAAAGCATCAGCTCTTTGCCCACCAAGAGGAGAGGCATCAGTGGGAGGAAGCTACGCTCGTTTGCTCGCACTGCCAGGCTAGGTTCGTCAGCGAATCCCTGCTAGATCATCACTCCAGGACCTTCTGCGGCAATGTCCAGAAGCGCTTCCAGTGCCGCAAATGCCCGCTTCGCTTCCGCTGGCGTGAGAACCTGAAGCACCACCTTTATTTGTCCCATCAGCAGGCTGAGATGCCGGCTGCAGAGGATTCTTCGCAAGCGGATGCCGAACTGCAATGTGGCGAGTGCCAGCGAACGTTCAAGATGCAAAAGGATCTCACACGGCACACCTTGATGCACGCCCGGGAGGCGACGATCTATCGGTGTCGTTGGTGTGCTCGTCGATTCTACCGCTGGGCCAATCTCCTGCAGCACATTGCACGGCACGGCATCCGGGCTAGTGAGTTGCACTATGCTGAGGCTCTCCTGGACGCCTATGGACATCCAGGCGGTCAGAAAACCGTGGAATGCCGGGTGTGCAATGTCAGCTTCGCCAGTATCGCCGCCCTGCGTCTGCATCTGGAAACCATGCCGGCAGGGAGCCACCATGAGCTCTCCTCGTTGAAGAACTACTCGATCACCAACCAAATGGGCTTCGAGCTGGAGCTGCAGGACTCGGAAACGGATGAGGATCAGCCAAAGCCGCCCGGTGTGCCTGCCTACTACACGTGCGGCATGTGCCAGTTGAGGTGTGTACGTAAATTCGAGCTGCACCAGCACCAGCAGGCCATGCATCGGCTGGAGAAGATTCCCGACGGCTGCGATCAGTGCATCTTCAAGAGCGTCTGTCCCGATCTCATTGCCCATCACAAGAGGACGCAGTGCGGTAACCAGGAGAAGCAGTTCACGTGCTCCCGCTGCGGCTACAAGTTCATGTGGGAGTCAAACCTGCTTACGCACATGCAGATGCAGCACGGAAAGACGGACGACCCGGACGGGGAGGAAGGAAAGGAGGCAGAAGCAGAGCCCAAGGCCGGGAGCCCGGTTTTCCAGTGTGCCCTGTGCCCCAGGAAGTACAACCGAAAGGACCGGCTTACAGCACATGTGAAAAAGTTCCATGGGCCCGATGGCAAGGGCCCCGAGGTGGTAAAGGTTCCCCCTACCAGAGCCGCCTCCCCCAAGGAACCGAAACGTTTCCTGTGCGCATTCTGCGGCAAGGCGGTCAGCTCCTCCTCCAACCTGATCATTCACATGCGCCGTCACACGGGCGAAAAGCCTTTCAAGTGCGAGTTTTGCGCGATGGCCTTCCCACGATCCTCAGACCTTCAGTGCCACCGGCGGACTCATACAGGAGAGCGTCCGCATGTGTGCACCGTGTGCCAGAAGGGATTCGCCCGCTCCTACAAGCTGCAGCAGCACATGCGCATCCACAGCGGCGAGCGACCGTACAAGTGCACCTACTGCGAGAAAAGCTTCACCCAGTCCAACGACCTGACACTCCACATCCGTCGGCACACGGGCGAGCGGCCTTACCAGTGTGGCATCTGCGGGGAACGTTTCATCCAGGGAACGGCGTTGAAAAATCATCGCCTGCAGCAGGGACACTTCGAGGAGGGTCAGAATTCTGGGGAGCCAGCAAGGCGCACGGTTTTGGAACAGTTTACTGTATGA
Protein Sequence: MLPSNICRTCAVQNTDLRPLSTCLAKDASKSCYDVLQELTQIDPLVESSGDNLPQHLCAECLARLESAYAFVEQARKVNGELLVRLRECLEEVPIDIPQEQPHIKTEVDIDEATPKFVVDVDSTGISSVEFKWQPESDSDRESAGVVSSDENDVEKKPYTLRRSARKIKQPVENNNEEPELPAEPSPNKRRRGRPPGPAKCQSMTSDGRHACKVCGKTFSWFRDMQRHARIHFEKSKAFVCDTCGKGFLRKDKYTFHLRCHEKREAKCKALQLGNEWRFAERLYSSGRLKRIECKLCGLKCPRIQDLRVHLASHQNVEGLLQLRENSDVIKEHYADQPGDLDGVKQRIIKDLTEGHLQKFASVVNFHGYELGLYDSDEESASGESKYECTACNLSLARKHQVVRHTLEEHAQSSPSELPWQRCGSCKIGFLCSRLYYSHVNTQCDSKLKRYRKRRLSARSPAPCATNSLPTLAQLRIHLVTHQSNMSGIDPEHSSTFFRSFHPNGLDSTPEELGVRIAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDDRNEDEKPTCHTCLLCGEVTSRLTSLLQHQNRAHSKATTKDLPCSCHDCGASFISDALLQQHRRRICAKKHFRHHCPSCNLRFIWPSNYELHLKTHHSHLEEDQLEEGGEHRDAKLQCDECEKVFIWHKDLTRHKRLHLPQSAQFECTHCDRKFHRKDGLKSHLRVHTEAQLVEQPLTSDSSGVLALLSRPHGCKQIQCMICLSRHSKISDLRTHLGAHRYGLSFTTETDISSISKSLYPEVEAALGTDELAERIMADIGQGVELDRFISITNEAGLELNLDSSETDTESEEEEEGPSSQNYACNLCPTEVKRKHQLFAHQEERHQWEEATLVCSHCQARFVSESLLDHHSRTFCGNVQKRFQCRKCPLRFRWRENLKHHLYLSHQQAEMPAAEDSSQADAELQCGECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHIARHGIRASELHYAEALLDAYGHPGGQKTVECRVCNVSFASIAALRLHLETMPAGSHHELSSLKNYSITNQMGFELELQDSETDEDQPKPPGVPAYYTCGMCQLRCVRKFELHQHQQAMHRLEKIPDGCDQCIFKSVCPDLIAHHKRTQCGNQEKQFTCSRCGYKFMWESNLLTHMQMQHGKTDDPDGEEGKEAEAEPKAGSPVFQCALCPRKYNRKDRLTAHVKKFHGPDGKGPEVVKVPPTRAASPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRLQQGHFEEGQNSGEPARRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00593959;
80% Identity: -