Basic Information

Insect: Drosophila bakoue
Gene Symbol: ZNF296
Assembly: GCA_008044335.1
Location: VNJL01012914.1:10321-14744[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0013 0.15 13.2 1.6 1 23 211 233 211 233 0.96

2 25 2.3 2.8e+02 2.9 3.8 1 21 240 260 240 262 0.84

3 25 0.022 2.6 9.3 0.4 2 23 294 315 293 315 0.95

4 25 0.07 8.4 7.7 0.2 1 23 388 411 388 411 0.94

5 25 0.36 43 5.5 0.9 1 23 452 474 452 474 0.97

6 25 0.019 2.3 9.5 0.0 2 23 486 507 485 507 0.96

7 25 0.0035 0.42 11.8 0.9 1 23 588 611 588 611 0.97

8 25 0.0012 0.14 13.3 1.1 2 22 622 642 621 642 0.94

9 25 0.11 13 7.1 4.4 1 23 651 673 651 674 0.94

10 25 0.0024 0.29 12.3 1.5 2 23 693 714 692 714 0.97

11 25 4.6e-06 0.00055 20.9 4.3 1 23 721 743 721 743 0.98

12 25 0.0077 0.92 10.7 0.6 1 23 878 901 878 901 0.91

13 25 0.02 2.4 9.4 0.7 2 22 909 929 908 929 0.91

14 25 0.028 3.3 9.0 3.3 1 23 938 961 938 961 0.93

15 25 3.6e-05 0.0043 18.1 1.4 2 23 980 1001 979 1001 0.97

16 25 8.5e-05 0.01 16.9 0.4 1 23 1008 1030 1008 1030 0.98

17 25 0.14 17 6.8 0.0 2 20 1057 1075 1056 1077 0.92

18 25 0.042 5.1 8.4 4.2 1 23 1123 1146 1123 1146 0.96

19 25 0.0017 0.2 12.8 0.8 1 23 1183 1206 1183 1206 0.97

20 25 0.001 0.12 13.5 1.3 1 23 1230 1253 1230 1253 0.97

21 25 5e-06 0.0006 20.7 0.2 2 23 1280 1301 1279 1301 0.95

22 25 0.0026 0.31 12.2 2.6 1 23 1307 1329 1307 1329 0.99

23 25 2e-06 0.00024 22.0 2.0 1 23 1335 1357 1335 1357 0.97

24 25 1.7e-07 2.1e-05 25.3 2.4 1 23 1363 1385 1363 1385 0.99

25 25 0.00065 0.078 14.1 0.1 1 21 1391 1411 1391 1415 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0013	0.15	13.2	1.6	1	23	211	233	211	233	0.96
2	25	2.3	2.8e+02	2.9	3.8	1	21	240	260	240	262	0.84
3	25	0.022	2.6	9.3	0.4	2	23	294	315	293	315	0.95
4	25	0.07	8.4	7.7	0.2	1	23	388	411	388	411	0.94
5	25	0.36	43	5.5	0.9	1	23	452	474	452	474	0.97
6	25	0.019	2.3	9.5	0.0	2	23	486	507	485	507	0.96
7	25	0.0035	0.42	11.8	0.9	1	23	588	611	588	611	0.97
8	25	0.0012	0.14	13.3	1.1	2	22	622	642	621	642	0.94
9	25	0.11	13	7.1	4.4	1	23	651	673	651	674	0.94
10	25	0.0024	0.29	12.3	1.5	2	23	693	714	692	714	0.97
11	25	4.6e-06	0.00055	20.9	4.3	1	23	721	743	721	743	0.98
12	25	0.0077	0.92	10.7	0.6	1	23	878	901	878	901	0.91
13	25	0.02	2.4	9.4	0.7	2	22	909	929	908	929	0.91
14	25	0.028	3.3	9.0	3.3	1	23	938	961	938	961	0.93
15	25	3.6e-05	0.0043	18.1	1.4	2	23	980	1001	979	1001	0.97
16	25	8.5e-05	0.01	16.9	0.4	1	23	1008	1030	1008	1030	0.98
17	25	0.14	17	6.8	0.0	2	20	1057	1075	1056	1077	0.92
18	25	0.042	5.1	8.4	4.2	1	23	1123	1146	1123	1146	0.96
19	25	0.0017	0.2	12.8	0.8	1	23	1183	1206	1183	1206	0.97
20	25	0.001	0.12	13.5	1.3	1	23	1230	1253	1230	1253	0.97
21	25	5e-06	0.0006	20.7	0.2	2	23	1280	1301	1279	1301	0.95
22	25	0.0026	0.31	12.2	2.6	1	23	1307	1329	1307	1329	0.99
23	25	2e-06	0.00024	22.0	2.0	1	23	1335	1357	1335	1357	0.97
24	25	1.7e-07	2.1e-05	25.3	2.4	1	23	1363	1385	1363	1385	0.99
25	25	0.00065	0.078	14.1	0.1	1	21	1391	1411	1391	1415	0.91

Sequence Information

Coding Sequence: ATGCTTCCCTCAAATATTTGCCGCACTTGTGCGGCTCAGAACACGGACTTGCGACCATTGTCCACCTGTCTGGCCAAAGACGCCTCAAAAAGTTTCTATGATGTGCTCCAGGAGCTAACGCAAATCGATCCTCTGATTGAGAGCTCTGGCGACAATCTGCCGCAGCATCTGTGCACCGAATGCCTGGCGAGATTGGAAAGTGCCTACGACTTTGTAGAACAGGCCAGAAAAGTTAACGGCGAGCTGTTGGTTCGTCTGCGAGAATGCCTCGAGGAAGTGCCCATTGACATTCCCCAGGAGCAGCCACACATCAAAACCGAAGTGGATATCGATGAGGCGACTCCCAAGTTTATTGTGGATATGGATTCCGCCGGAATATCGTCTGTTGAGTTCAAATGGAAGCCGGAAAGTGACAGTGATGGGGAATCTGCAGGGGCAGCATCCAGTGATGAGAATGCTGTCGAGAAGAAGCCCTATTCCTTAAGACGCAGTGCTCGTAAAATCAAGCAGCCTGTAGAGAATACCAATGGGAAGCCAGAGTTGCCAACAGAAGAACCATCGCCCAGCAAACGTCGTCGAGGCCGTCCGCCAGGCCCGGCCAAGCGCCAGGCGATGACCTCCGACGGACGCCACGCTTGCAAGGAGTGCGGAAAGACCTTCTCCTGGTTCCGCGATATGCAACGCCATGCCCGTATCCATTTCGAGAAATCCAACGCGTTCGTTTGTGACACCTGCGGCAAGGGCTTCCTGCGCAAGGACAAGTACACATTCCACCTGCGCTGCCACGAAAAGCGTGAAGCGAAATGCAAGGCTCTTCAGCTTGGTAACGAGTGGCGCTTCGCCGAACGGCTGTACAGTTCCGGCAGGCTGAAGAGAATCGAGTGCAAGCTGTGTGGCCTTAAATGTCCCCGAATTCAGGAGCTCAGAATTCACTTGGTCAGCCATCAGAATGTGGAGAGCCTGAAACAGTTGAGTGGGAACAGCGAAGTGATAAAGGAACACTATGCCGACCAGCCAGGTGACTTGGACGGCGTCAGGCAGCAAATTATCAAGGACCTAACGGCGGGGCACTTGGAAAAGTACGCTTCCGTGGTGAATTTCCATGGGTATGAGTTGGGATTGTATGACTCGGACGAGGAATCTGCCAGCGGAGAGTTCAAATATGAGTGCACGGCGTGCAATCTTTCCTTAGCGAGAAAATATCAAGTGGTGAGGCACACGCTGGAGGAGCACGCCCAATCCTCATCTTCAGAGCTACCCTGGAAACGCTGCGGCTTCTGTAAAATTGGATTCCTCTGCTCCACACTCTACGATTGCCATGTGAATACCCAGTGTGAGAGCAAACTGAAGCGGTATCGGTGCGCCAAGTGCCCGGGGAAGTTTATGTGGCCGGAGAATCTGTACAGGCACGCCTGCTCCCATCGCCACCAGGAAGTGACGTCTGCCCGCCAGATCTCCTGCTCCTTGTGCGATGAATTCCTGCCCACATTGGCCCAGTTGCGGATACACTTGGTTACTCACCAGTGCAGCATGAGTGGCATCGATCCGGAGCTCAGTTCCACGTTCTTTCGGTCCTTCTATCCCAACGGGCTGGACTGCAGCCCGGAGGAGATGGGTGTCCGCATAGCCGAGGACTTCGAGGTCCAGGACTTCGATCGCTACTACAACGCTTGCACGGGCAGTGGACAAGAGCTGGATCTCTTTGATTCCGAGACGGAGCAGAGCGGGGACGAGCGCGAGGAGGACGAAAAGCCGACCTGCCACACCTGTTTGCTGTGTGGAGAGGTGACGAACAGACTCACGACCCTGCTGCAGCACCAGAACAGAGCCCATTCAATAGCGACGACGAAAGATTTGCCTTGTTCCTGCCACGACTGTGGCGCTAGCTTCATAAGTGATGCCTTGCTGCAACAGCACCGCCGGCGTATCTGCGCCAAGAAGCATTTCCGTCATCACTGCCCGAGCTGCAATCTCCGATTCATCTGGCCGAGCAACTATGAGTTACATCTGAAGACCCACCATAGCCATTTGGAGGACGACCAACTCGGGGAGGGTGAGCATCGGGACGCAAAGCTGCAGTGCGACGAGTGCGAAAAGGTCTTCATTTGGCACAAGGATCTGACGCGTCACAAGCGCTTGCACCTACCGCAGTCGGCGCAGTTCGAGTGTCCGCATTGCGACCGAAAGTTTCACCGCAAGGATGGCCTCAAGTCCCACCTGCGGGTCCATACAGAGGAACAGCTGGTGGAGCAGCCTCTTAAGTCCGACAGCAGTGAGGTTCTTGCCCTGCTCTCCCGTCCCCATGGCTGCAAGCAGATCCAATGCATGATCTGTCTCTCACGCCACTCCACGATCTCTGATCTGCGAACCCACCTGGGCGCCCATCAATACGGATTAAGCTTTTCCACAGAGACCGATATTTCCAGTATCTCAAAGTCGCTGTATCCGGAATTGGTAGCGGCCTTGGGCAGAGGTGAACTGGCGGAGAGAATTATGACAGATGTCGACCAAGGAGTGGAGCTGGATCGATTTATTTCCATCACCAATGAGGCCGGGTTGGAGCTCAGCTTGGACAGCAGCGAAACGGACACTGAATCCGAGGAAGAAAGGAAAGACCCGTCCAGTCGGAACTACGCCTGCAATCTGTGTCCCACGGAGGTAAAGCGAAAGCATCAGCTTTATGCCCACCAAGGGGAAACTCATCGGTGGGAGGAGGCACCGCTCGTTTGCTCGCACTGCCAGGCTAGGTTTGTCAGCGCGTCCCTGCTAGATCATCACTCCAAAACCTTCTGCGGCAATGTTCAGAAGCGCTTCCAGTGCCGCAAATGCCCGCTTCGCTTCCGCTGGCGTGAGAACCTGAAGCACCACCTATATTTGTCCCATCAGCAGGCTGAGGTACCAGCTGCAGAGGATCCTTCGCAACCGGATGCCGAATTGCAATGTGGCGAGTGCCAGCGAACGTTCAAGATGCAAAAGGATCTCACACGGCACACCTTGATGCACGCCCGGGAGGCGACGATCTATCGGTGCCGCTGGTGTGCTCGTCGATTCTACCGCTGGGCCAATCTCCTACAGCACATCGCACGTCACGGCATCCAGGCTAGTGAGTTGCACTATGCCGAGGCTCTCCTGGACTCCTATGGACATCCAGGCGGTCAGAAAACCGTGGAGTGCCGAGTGTGCAATGTCAGCTTCGCAAGCATCGCTGCCCTGCGTCTGCATTTGGGAACCATGCCGGCAGGCAGCCACCATGAGCTCTCCTCGTTGAAGAACTACTCGATCACCAACCAAATGGGCTTCGAGCTTGAGCTTCAGGACTCGGAAACGGATGAAGAGCAGTCAAAGCCGCCCGGTGTGCCTGCCTACTACACGTGCGGCATGTGCCAGTTGAAGTGTGTGCGGAAATTTGAgctccaccagcaccagcaagcCATGCATCGGCTGGAGAAGATTCCCGACGGCTGCGATCAGTGCATCTTCAAGAGCGTCTGTCCCGATCTCATTGCCCATCACAAGAGGACGCAGTGCGGTAACCGAGAGAAGCAGTTCACGTGCTCCCGCTGCGGCTACAAGTTCATGTGGGAGTCAAACCTGCTTACGCACATGCAGATGCTGCACGGAAAGGCGCACGATCCGGACCAGGAGGAAGACAAGGAGGCAGAAGGACCTAAGGCCGGAAGCCTGGTGTTCCAGTGTGCCCTGTGCCCCAGGAAGTACAACCGAAAGGACCGGCTTTCAGCACACGTTAAAAAGTTCCACGGGCCCGATGGCAAGGGCCCCGAGGTGGTAAAGGTTCCCCCAACCAGAGTCGCCTCCCCCAAGGAACCGAAACGTTTCCTGTGCGCATTCTGCGGCAAGGCGGtcagctcctcctccaacCTGATCATCCACATGCGCCGGCACACGGGCGAAAAGCCTTTCAAGTGCGAGTTCTGCGCAATGGCCTTCCCACGATCCTCAGACCTTCAGTGCCACCGACGGACTCATACAGGAGAGCGGCCGCATGTGTGCACCGTGTGCCAGAAGGGGTTCGCCCGCTcctacaagctgcagcagcacatGCGCATCCACAGCGGCGAGCGACCGTACAAGTGCACCTACTGCGAGAAGAGCTTTACCCAGTCCAATGACCTGACACTCCACATCCGTCGGCACACGGGCGAGCGGCCTTACCAGTGTGGCATCTGCGGGGAGCGTTTTATCCAGGGAACGGCGTTGAAAAATCATCGCCTGCAGCAGGGACACTTCGAGGAGGGTCAGAATTCTGGGGAGCCAGCAAGGCGCACGGTTTTGGAACAGTTTACTGTAtga
Protein Sequence: MLPSNICRTCAAQNTDLRPLSTCLAKDASKSFYDVLQELTQIDPLIESSGDNLPQHLCTECLARLESAYDFVEQARKVNGELLVRLRECLEEVPIDIPQEQPHIKTEVDIDEATPKFIVDMDSAGISSVEFKWKPESDSDGESAGAASSDENAVEKKPYSLRRSARKIKQPVENTNGKPELPTEEPSPSKRRRGRPPGPAKRQAMTSDGRHACKECGKTFSWFRDMQRHARIHFEKSNAFVCDTCGKGFLRKDKYTFHLRCHEKREAKCKALQLGNEWRFAERLYSSGRLKRIECKLCGLKCPRIQELRIHLVSHQNVESLKQLSGNSEVIKEHYADQPGDLDGVRQQIIKDLTAGHLEKYASVVNFHGYELGLYDSDEESASGEFKYECTACNLSLARKYQVVRHTLEEHAQSSSSELPWKRCGFCKIGFLCSTLYDCHVNTQCESKLKRYRCAKCPGKFMWPENLYRHACSHRHQEVTSARQISCSLCDEFLPTLAQLRIHLVTHQCSMSGIDPELSSTFFRSFYPNGLDCSPEEMGVRIAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDEREEDEKPTCHTCLLCGEVTNRLTTLLQHQNRAHSIATTKDLPCSCHDCGASFISDALLQQHRRRICAKKHFRHHCPSCNLRFIWPSNYELHLKTHHSHLEDDQLGEGEHRDAKLQCDECEKVFIWHKDLTRHKRLHLPQSAQFECPHCDRKFHRKDGLKSHLRVHTEEQLVEQPLKSDSSEVLALLSRPHGCKQIQCMICLSRHSTISDLRTHLGAHQYGLSFSTETDISSISKSLYPELVAALGRGELAERIMTDVDQGVELDRFISITNEAGLELSLDSSETDTESEEERKDPSSRNYACNLCPTEVKRKHQLYAHQGETHRWEEAPLVCSHCQARFVSASLLDHHSKTFCGNVQKRFQCRKCPLRFRWRENLKHHLYLSHQQAEVPAAEDPSQPDAELQCGECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHIARHGIQASELHYAEALLDSYGHPGGQKTVECRVCNVSFASIAALRLHLGTMPAGSHHELSSLKNYSITNQMGFELELQDSETDEEQSKPPGVPAYYTCGMCQLKCVRKFELHQHQQAMHRLEKIPDGCDQCIFKSVCPDLIAHHKRTQCGNREKQFTCSRCGYKFMWESNLLTHMQMLHGKAHDPDQEEDKEAEGPKAGSLVFQCALCPRKYNRKDRLSAHVKKFHGPDGKGPEVVKVPPTRVASPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRLQQGHFEEGQNSGEPARRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00593959;
80% Identity: -