Basic Information

Insect: Drosophila santomea
Gene Symbol: -
Assembly: GCA_016746245.1
Location: NC:18903367-18907260[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.37 24 5.3 2.5 2 23 330 352 329 352 0.95

2 18 0.2 13 6.1 0.2 1 23 359 384 359 384 0.94

3 18 0.27 17 5.8 4.5 3 23 396 416 395 416 0.93

4 18 0.036 2.3 8.5 0.1 3 23 457 478 456 478 0.95

5 18 0.0015 0.097 12.8 1.0 3 23 486 506 484 506 0.95

6 18 0.11 7.1 6.9 0.1 1 23 514 537 514 537 0.96

7 18 0.00045 0.029 14.5 0.3 2 23 542 563 541 563 0.97

8 18 2.3 1.5e+02 2.8 0.1 1 20 571 590 571 592 0.91

9 18 0.0032 0.2 11.8 0.4 1 22 611 632 611 635 0.90

10 18 0.17 11 6.3 1.5 3 21 642 660 642 661 0.90

11 18 0.0039 0.25 11.5 0.8 1 23 680 705 680 705 0.96

12 18 0.13 8.5 6.7 1.3 2 23 723 745 722 745 0.94

13 18 0.00078 0.05 13.7 0.3 2 23 751 773 750 773 0.93

14 18 0.0085 0.54 10.5 0.1 2 23 777 799 776 799 0.95

15 18 2.3e-05 0.0015 18.5 2.2 1 23 805 827 805 827 0.98

16 18 0.0093 0.59 10.3 2.2 1 23 831 854 831 854 0.93

17 18 4.7e-06 0.0003 20.7 1.1 1 23 860 883 860 883 0.97

18 18 1.3e-05 0.00082 19.3 0.2 1 23 887 915 887 915 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.37	24	5.3	2.5	2	23	330	352	329	352	0.95
2	18	0.2	13	6.1	0.2	1	23	359	384	359	384	0.94
3	18	0.27	17	5.8	4.5	3	23	396	416	395	416	0.93
4	18	0.036	2.3	8.5	0.1	3	23	457	478	456	478	0.95
5	18	0.0015	0.097	12.8	1.0	3	23	486	506	484	506	0.95
6	18	0.11	7.1	6.9	0.1	1	23	514	537	514	537	0.96
7	18	0.00045	0.029	14.5	0.3	2	23	542	563	541	563	0.97
8	18	2.3	1.5e+02	2.8	0.1	1	20	571	590	571	592	0.91
9	18	0.0032	0.2	11.8	0.4	1	22	611	632	611	635	0.90
10	18	0.17	11	6.3	1.5	3	21	642	660	642	661	0.90
11	18	0.0039	0.25	11.5	0.8	1	23	680	705	680	705	0.96
12	18	0.13	8.5	6.7	1.3	2	23	723	745	722	745	0.94
13	18	0.00078	0.05	13.7	0.3	2	23	751	773	750	773	0.93
14	18	0.0085	0.54	10.5	0.1	2	23	777	799	776	799	0.95
15	18	2.3e-05	0.0015	18.5	2.2	1	23	805	827	805	827	0.98
16	18	0.0093	0.59	10.3	2.2	1	23	831	854	831	854	0.93
17	18	4.7e-06	0.0003	20.7	1.1	1	23	860	883	860	883	0.97
18	18	1.3e-05	0.00082	19.3	0.2	1	23	887	915	887	915	0.89

Sequence Information

Coding Sequence: ATGTCGGAAAACGCGAAAAACAATAGCTGCCTGCATTGCAGCGTACTCAGTACGAAATACCAGTACCAGGAGATCTTCGATGAGTTCGGAATTGAACTGGGACTGCAGTCCCTACTGGCCAAGCACTTCCTGTTCGAAGTGTCTCCCGATCCGCGGAAGCAGCAGCTTCTGTGCGAAGTTTGTGTCAACAATCTCATCCGCCTTTTTGATATTGATGAACTGGAAAGAGAAAGAGATGCTGCGAAGGATGTGGCTCAGTGCAAAGATCCCAAGGCGGAGGACCCCATCATCATTACCGATGTCCAAGCAACTTCACCAGCTGCAAAGCCCGTCAAGAAAGCTGCGCCCTCCAGACCCTTCACTAAGGTCCTGCGACCAGTGCCCATTATTCCCATCCGGGAACCAAGTGCCCGGATAAGAAAtaaagctgctgctgcttcccATGTAACACCTGATGCATCTAGATCTCCTGAGCCATCACCACAGCCGTCTTCCCCAGAAGCTTCTGTCCTTAAAAACGATAATAATCTGGTTGTGAAAGTCGCAGATCAGGAGCAGTTCAGTGTCCTTATACAAAATATTCTGGACGGAGAGGAAGCTATTGTTGAGGATGACACCGCAGTGAAAGAAGAGTCCAGTGAAGCTGTCCCCGTGGAAACAGAAACCCCGGGTCAAATAGTCATCCTAAACAGCGAGGCTGGGGCAGAAACTAATCTGGATGAGAATGTTTACATATACGAGCATAATGATGTTATGGATCCCAATTTGGACAATGTTAAGGTAAAACCAATAAGTTGTTCGTCTAGATTGGTAGCTCAAGCTGAAGAAAGTCAAAGCGATGATGACATTGACGAGGGAGAGACTAGCAATATTGTTCTGTTTAACTTTGTGGACATCAAAGAAAAGGATGATGTTGATAATATACCAGAGTACTTGTCCACCGTGGTGAAGACAAGCTTTGAAAAGCTGACATTTGAGTGGTGCACTGTGTGCAAGCACTGCTCCCTGAAGTGTCCCACATTCGAGAGCCTTCTTGGTCATTTGTTAAAGGCCCACAAAACACGAAAAGATGTCCACCAGTGTCCCATTGAAGGATGCAACAAGGAGTTGAAAGGACGCAAATTCTTAGCCATGCATCTTGTTATGTTGCACGCACCAGTTGCTGAAATTGCTATCTATGGCTGCTGTCCGGAATGTAAACTGACGttttcaaacattttgcaGTACAACAAGCATTCTTGTGCtcatgtaattaaaaaaaagcgAGGTATTCGCTCATTTTGTGAAATGTGTTCGCTAGAGTTTCCTTCTTGGAAGCGttttaatttcCACAACCAGTTCCATCTAGAAAAGCATAGACCTCGAGCGTGCTTCGTCTGTGACTATGCCAGTACAAACATAGATGAACTTTTCCAGCATTTGAATTATGCGCATGAGCCAGTGGGAACCTTATTCTGCGACCTTTGCGACCGTACTTTCCGGGACTCTTCTGTTTTTATGGAGCACAATAAGTCACATGCCAATGTTAGCAGCACGACCTACTCTTGCGGCGAATGTATGGCGAACTTTGAGTCGCGGGGTCGGCTAAATGGACACATGAGAGCGATGCATGGCAGCGTAATAAGCTGTGAACTCTGTTCCCGCGAATTTGCCACTGAAGCTACTTACAATATTCACATGAAGAAGCATCTGATTATCGAAAAAGATGTGCACGTGTGCAGAACATGCGGTCTTTTAAGTGACAGCCGCGAAACCCTTCTTGCGCATGTGGAATCCGTGAAGACTGCCTGTTTTGGCTCCAAGATATACGTGGAGCTCCTACGGGATGCTTATGTGTGCGAGTACTGCTCCTCGTACTTCAAAGAAAAGGACAGTCTCCAAGCCCATCGTGACTCCGGGGTACATAAGGATGGAGTGTTTTGGTGTCAGCCCTGCGGCAAAGAATTCGCGCATATGAAACTATATCGCCATCACCTTCGGAACTATCAACAACTTCGAGCGGACTCAACACATCGCAGGCTAGAAATTTGTGTTTACTACATGTGCGATCAAGAGaACTGCTCAGAGTCTTACGTGAACTGGAACTCCTTGTACACACACAAGCGCCGCACACACGAATCTTCGAATAAGCAAGCGGAGAGGAGTTCAAGGTCTGCCCAGGAATGGGTTTGTCAGTTTTGCTTAAAAGAATGCCGGTCCAAAATGTCCTTGTCCGTTCATGTGGCTAGGAGTCATAACAATGATAACGTCACCTGTCCTTTATGCAATGCCTCATACAAGAGCCGTGATGCTCTGGCTAAGCACCATGCCTATTGGCATGAACCAATAGAGTGTCCGGAATGCTTTAAAATAGTCAAAAATCGACGGAATTATGACACTCATGTAAATGTTGTGCATTCGAATAAGAAGCGCTATTCTTGCAATGTCTGTCAAAAGGGGTTTTATCACAAAAGTGAAATGGAGGCTCATCAAAAGCTTCATGGACAGTCTTACAACTGCGAACACTGCAGCTTCACCACCAGGAACAAAAAGTCCCTTTCTGTTCATGTTCTTGGTCAGCACTATAAGCGGTTTGCTTTCGAGTGCAACGTGTGTAAGAAGAGGTTTGGACGCAGTCAGGGATTGAAGACGCACATGCAGCGAGCCCATGGGGATAAATACACGTGCCGCGACTACTTCGACGGCGGCTGTGGACGGACCTTTGTAAACAGTTCCCAGTTGAATGTGCATGTCCGAAAGGTCCACGACGGCATTATTTTGCTACAGGAGGATGTGGTTGAAGAGGACGAATGCATTACCGATGATGTTCCATCCACATCTAAAAAGCGCTGCCTTCGCTTGAGTGAAAACAATATTGAGTTTATAGAGGAAGCAGATGGGGATGATATAGAAATGGGAgaggatgacgatgaggacgaCGATTTTATCGACGAGATCCAAGATCAGGATCCACAAAATTGA
Protein Sequence: MSENAKNNSCLHCSVLSTKYQYQEIFDEFGIELGLQSLLAKHFLFEVSPDPRKQQLLCEVCVNNLIRLFDIDELERERDAAKDVAQCKDPKAEDPIIITDVQATSPAAKPVKKAAPSRPFTKVLRPVPIIPIREPSARIRNKAAAASHVTPDASRSPEPSPQPSSPEASVLKNDNNLVVKVADQEQFSVLIQNILDGEEAIVEDDTAVKEESSEAVPVETETPGQIVILNSEAGAETNLDENVYIYEHNDVMDPNLDNVKVKPISCSSRLVAQAEESQSDDDIDEGETSNIVLFNFVDIKEKDDVDNIPEYLSTVVKTSFEKLTFEWCTVCKHCSLKCPTFESLLGHLLKAHKTRKDVHQCPIEGCNKELKGRKFLAMHLVMLHAPVAEIAIYGCCPECKLTFSNILQYNKHSCAHVIKKKRGIRSFCEMCSLEFPSWKRFNFHNQFHLEKHRPRACFVCDYASTNIDELFQHLNYAHEPVGTLFCDLCDRTFRDSSVFMEHNKSHANVSSTTYSCGECMANFESRGRLNGHMRAMHGSVISCELCSREFATEATYNIHMKKHLIIEKDVHVCRTCGLLSDSRETLLAHVESVKTACFGSKIYVELLRDAYVCEYCSSYFKEKDSLQAHRDSGVHKDGVFWCQPCGKEFAHMKLYRHHLRNYQQLRADSTHRRLEICVYYMCDQENCSESYVNWNSLYTHKRRTHESSNKQAERSSRSAQEWVCQFCLKECRSKMSLSVHVARSHNNDNVTCPLCNASYKSRDALAKHHAYWHEPIECPECFKIVKNRRNYDTHVNVVHSNKKRYSCNVCQKGFYHKSEMEAHQKLHGQSYNCEHCSFTTRNKKSLSVHVLGQHYKRFAFECNVCKKRFGRSQGLKTHMQRAHGDKYTCRDYFDGGCGRTFVNSSQLNVHVRKVHDGIILLQEDVVEEDECITDDVPSTSKKRCLRLSENNIEFIEEADGDDIEMGEDDDEDDDFIDEIQDQDPQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00619305; iTF_00539813; iTF_00596804; iTF_00504843; iTF_00592540; iTF_00607923; iTF_00543221;
90% Identity: iTF_00619305; iTF_00504843;
80% Identity: -