Basic Information

Insect: Drosophila rhopaloa
Gene Symbol: RREB1
Assembly: GCA_018152115.1
Location: JAECXI010000003.1:22747674-22754309[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0047 0.34 11.4 0.6 1 21 244 264 244 266 0.96

2 12 0.0035 0.25 11.8 0.1 1 20 276 295 276 297 0.94

3 12 1.7 1.2e+02 3.3 3.7 2 19 412 429 412 431 0.97

4 12 0.0071 0.52 10.8 0.1 1 23 583 605 583 605 0.97

5 12 1e-05 0.00072 19.8 0.7 1 23 615 637 615 637 0.99

6 12 0.00067 0.049 14.0 2.0 1 23 643 666 643 666 0.97

7 12 0.0025 0.18 12.2 2.1 1 23 928 951 928 951 0.95

8 12 7e-05 0.0051 17.1 0.3 2 23 1330 1351 1329 1351 0.97

9 12 0.12 8.5 7.0 6.3 1 23 1357 1380 1357 1380 0.97

10 12 6.3 4.5e+02 1.6 2.0 1 23 1495 1518 1495 1518 0.83

11 12 0.0068 0.49 10.9 0.5 3 23 1583 1603 1581 1603 0.96

12 12 0.0011 0.082 13.3 4.8 1 23 1609 1631 1609 1631 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0047	0.34	11.4	0.6	1	21	244	264	244	266	0.96
2	12	0.0035	0.25	11.8	0.1	1	20	276	295	276	297	0.94
3	12	1.7	1.2e+02	3.3	3.7	2	19	412	429	412	431	0.97
4	12	0.0071	0.52	10.8	0.1	1	23	583	605	583	605	0.97
5	12	1e-05	0.00072	19.8	0.7	1	23	615	637	615	637	0.99
6	12	0.00067	0.049	14.0	2.0	1	23	643	666	643	666	0.97
7	12	0.0025	0.18	12.2	2.1	1	23	928	951	928	951	0.95
8	12	7e-05	0.0051	17.1	0.3	2	23	1330	1351	1329	1351	0.97
9	12	0.12	8.5	7.0	6.3	1	23	1357	1380	1357	1380	0.97
10	12	6.3	4.5e+02	1.6	2.0	1	23	1495	1518	1495	1518	0.83
11	12	0.0068	0.49	10.9	0.5	3	23	1583	1603	1581	1603	0.96
12	12	0.0011	0.082	13.3	4.8	1	23	1609	1631	1609	1631	0.99

Sequence Information

Coding Sequence: ATGCTCGCCGCACAGCAGCAGCACAACAACAGCACGGCGGAGTCGGAGATGGAGCGCCAGCGACGGGACTCCACCACCTCGGAGTCCTCCCTGGAGCACCTGGACCTGGGTCGCACGCCCAAGAAACTGGGGGGCACCGGCGGCTCCACTCAGACCACATCCACTCCCCACGAACTGGTGGTCACATCGCGCAAGCGCAAACTGCGTCAGTTGCAACAGCACCAGCCCTTGAGTCACATGCAGCAGGATCTGCTCACTGACGAGGAGGAGGATGAGGAGGAGGAGGAGGATAGGGATGGGGACGCGGAGGAGCAGGTGGCCGCCACTGGGGCCAGGAGCCTGGGGCGCCACAAGCAGCGACGCAGTGGCGCCACCACCCAGGCCTCCATTGTGGTGGACTACAGCAGTGGCGATGCCAGTTCGCTGCGCAAGAAGTTCCGCCTCAATCGCTCCGCCGGCAGTCTCTCGGAATCGGGATTCGTGGACGCCAGCAGCACGGCGCACAGTAGTGGCTATCTGGGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTCCTCGCCCCAGGGACTGTGCCTCTCCAGCGGCGAGTCGGGAATCGGGGCCGGGGACGAGCACATGAAGTACGTGTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCCGGTGCCACAATTACGCCAACGGCGACACGGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCATCCGCCTCGTCTCTGGACAGACACGCTAACAACAATCTCAAGGATTTGGTGGAGCTGGAGGACGACCAGGATGAGGAGGCGTCGGAGAAGAGGCGTCTGCGAACGACCATCAACAACAACATCATAGATAGGGAAACGCAGGAGGAGATCGAGGAGGAGGACGATGCGGATGTGGCCATGCTGACCAGCACACCGGATGTGGCCACCCTGCTGGCCGGAGCCAGTGCATCCGGGGCAGCCTCTCGCTCGCCCTCACCCTCGCCATCCGACGATCACGGCCTGCTCCTCAGCTGTCCCGCCTGCGGAGCCTCCGACTTTGAGACCCTGCCCGCCTTGTGCGCCCACCTGGATGCGCGCCACTCGGACATCCCGGCCAAGTGCCGCGACTGCGAGGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCCCACTGCTGCCGCGGTCCATCCCTGGGCCTCGGCGGAATGCCTCCACTGTTGGGAGCCAGCAGCTCGCCGCTGCACGACGAGGAGCCCGAGGATGTGGACAGGGAGGAGGAGGAGGAGGAGGAGGATCGCGACCGCAAGGAGCGCATGCCGCACCAGGGCGAGGACTTCTTCCACCAGCTGTACCTCAGGCAGAAGGCGGCCGGCGGAGCAGCCAGTGGCGGTGGATCCGCCATCTCGCATCCCCCCTCCCCCATCAAACACGAGCCGGCGGACAGCAAGGACCTGGCCGACATCCAGAGCATCCTGAACATGACCAGCTCCAGCTCCAGCTTCCTGCGCAACTTTGAGCAGTCGGTGAACACACCCAGCTCCAGCCAGTACAGCCTGGACGGGCGGGACCTGGAGGAGGAGGCCCAGGACGCGTTCACCTCGGAGTTCCGCCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCTCGGCGGTGTTCCCCAACCTGCGTGCCCTGAAGGGCCACAACCGCGTGCACCTGGGTGCAGTGGGTCCCGCCGGTCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGCGACCGACCCTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGCGAGCGGCACCTGCGCAATCGGCACGGGAAGACCAGTCGCGAGGAGGTGAAGCGGGCCATCGTCTACCATCCGGCGGAGGATGCCAACGGCTGCGAGGACGGCAAGTCGCGTCTGGGCGAGGACCTGGCCGACATGAGTTTCCGCTCGATCAGTCCCACGCCGCCGCCGCCACCAGCTCCTCCGATCTCGGAGAGCCCCGTCTCCGTCACCGCCGGCTGCCAGCTGAAGCACATGCTCCTGGGCGAGAGCCACCTGGGTGCGCCATTGCTGGTGGACAAGAAGCCGTCGGTCTCCGATGCTGCCCATCATCAGCAGCAGGAGAAGGGCCTGGACTTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCCACGGCAGGAGCACCGGCCACGCCCTCGGTCAGTCCGCCCATGGTCATGCCGCCCGTGGTGGCACCTCCCGTTGGCCCAGCCACTCCCGATCTGGCCGCCGCCCTGGAGCAGCAGCAGTTGCTCCTCGCCCAGCAGCAACTCTTCGGCGTGGGTGGAGATACCGCCTCGCAGTACATGCAGCAGCTGTTCCGCAGCCTGATGTTCCAGTCGCAGTCGCCGGGATTCCCCTTCTTCCCCTTCATGGCACCGCCCCCGCCGCCGCAGCAGGCGGCCAATCCGGAGAAGCCACCGCTGGTGAGTCCGCCCAGCCACCGGCTGAATCCCATGGCCGTCGGAGTGGGCGTGCCAGTGCCTCCGGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGCCCAAGCAGAAGCAGCGTCGCTACCGCACCGAGCGCCCCTTCGCCTGCGACCACTGCTCGGCGAGATTCACCCTGCGCTCGAACATGGAGCGCCATGTGAAGCAACAGCACCCGCAGTTCTACGCCCAGCGCCAAAGGAATGGCCACCACGTGATGAGGGGCAGAGGTGCCTCCAATGCCGCCGCCGCCGCCGCTGCCGCCGCAGCAGCAGCAGCCGTGATGGGACATGGTGGCGCCTCCGCCGGCTCCAATTCATCCGCAGCCGCCGCCAACCATCACCACGGCCACGCCCCCATCTCAGAGCAGGTGAAGTACGCCATTCTGGCGCAGCAGCTGAAGGCCCACAAGAACACCGATCTCCTGCAGCAGGCCCTGGCCCACGGCTCCAGCAGCGTGGCCGGCAATCCCCTCCTGCACTTCGGCTACCCGCTGGCCAATCCCGCTGCCCTGCACAACGGCGTCCAGGCGAACGGCCAGAGCCAGTCCCTGGCCATGGACGATGACGAGCCCAAGCTGGTCATCGACGAGGACGAGAACGAGCACGAGCACGAGGTGCCCGAGGAGGTGGACGACTTCGAAGAGGACGAGGACGAGGAGGAGCTGGAGCTGGAGGAGCCGGAGGAGGAGGCGGAAGTGGAAGCGGAAGCCAACCAGGCTCGTGAGGAGTTCGACGAGGAGGATGAAGAGGAGGAGGAGCTGGCCAAGCCATTGGACCAGCCAGCCAACGAGGCAGCCCAGAAAATGGCCGAGACCATCTTGGAGCAGGCCATCAAGGCGGGCAAGCCCTCGAGGAGTCCCTCCATCGAGCCACCGCCAGCCAATCCCTCCCAGACGACCACCACCACCAGCATGCAGGAGCCACAGGCCACACCCGCAGCCACTCCCACTCCCACAACCACGACCACACCCACCAACCCCAGCAGTCTGAAGACCATGATCGCCCAGGCCGAGTCCGTGGGCAAGTCCCTAAAAGAGGTGGCCAGCTCGCCGTTCAAGGACGAGTCACAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGTCTGGTGGCCTCCGGGAGCGCCAGCGAGAGCAACAACAGCGGCACCGAGGACGTCACGAGCAGCAGCTCCGGCTCCGAACCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAACCGCGTCTCCTGCCCCTACTGCCAGCGGATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTTACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACGAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTGGAGTCGGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCCATCCCGGTGCCCAAGTCCGTGGAGGAGATCGAGCTGGAGGAGCAGCGCCGCCGTCGCGAGGCGGAGCGGGAGAAGGAGCGCGAGCGAGAGCTGGAGCGGGAGCGCGAGCGGGAGAGGGAGCTGGAGCTGGAGCGGGAGCGGGAGCGCGAGCTGGAGAAGGAGAAGGAGCGGGAGCGGCAGCAGCTCATCCAGAAGCTGGCGGCCCAGATGAATGCCGCCGCCGCTGCAGCAGCTGGAGCAGCTGGCGGTCCGCTCGGGGATGCAATGGCTGGCGGGGATCTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTCGCAGAGCGGCTGCAGTGCCTAGAGCACATCAAGCAGGCCCACGCCCACGAGTTCGCCCTGCTGCTGGCCAAGGGGGCCATCGAGAACGAGTGCCTGGATCCCCAGCAGGCCGCCAATCCCAATCCCAATCCCGGCCAGCAGCAGTCGGCGGCCCACTCCGACGACGAGGGCCTGGCCTCCAACGGCGGCAGCAGCCGGGGCAAGTACCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACCGAGGACCTGCGTCGCCACATGCGCACCCACTCCGGCGAGCGGCCCTTCCAGTGCGACATCTGCCTGCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGCCGCGCCCACAACGGCGACAATCCGGGCTCCGACTGCTCCGACGACGAGCAGGTGGCCAGTCCGCCCAACACCCCCCTTCCCGTGCCCGCCGTGCCCCAGTCGCACAACAACAACCAGAACAGCTGCCACAATAATAACAACACCAACTCCAGCTCCAAGCTGGGCCTGAAGCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCCAGCGAGTGGCGGGCCAGTCGGCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCCACGCCCTCGGGCGGAGGAGCCGTCGCAGGATCGGACCTCATCGGCAACCTGCTGGGCATCAGCGACCAGGGCATCCTCAACAAGCTCCTCTCCTCCGCCGACGAGGCGGCCAAGCTGCTCGGCGTGGACAACAAGTAG
Protein Sequence: MLAAQQQHNNSTAESEMERQRRDSTTSESSLEHLDLGRTPKKLGGTGGSTQTTSTPHELVVTSRKRKLRQLQQHQPLSHMQQDLLTDEEEDEEEEEDRDGDAEEQVAATGARSLGRHKQRRSGATTQASIVVDYSSGDASSLRKKFRLNRSAGSLSESGFVDASSTAHSSGYLGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSPQGLCLSSGESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHANNNLKDLVELEDDQDEEASEKRRLRTTINNNIIDRETQEEIEEEDDADVAMLTSTPDVATLLAGASASGAASRSPSPSPSDDHGLLLSCPACGASDFETLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGPSLGLGGMPPLLGASSSPLHDEEPEDVDREEEEEEEDRDRKERMPHQGEDFFHQLYLRQKAAGGAASGGGSAISHPPSPIKHEPADSKDLADIQSILNMTSSSSSFLRNFEQSVNTPSSSQYSLDGRDLEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDANGCEDGKSRLGEDLADMSFRSISPTPPPPPAPPISESPVSVTAGCQLKHMLLGESHLGAPLLVDKKPSVSDAAHHQQQEKGLDFSMDVLDLSKKPTAGAPATPSVSPPMVMPPVVAPPVGPATPDLAAALEQQQLLLAQQQLFGVGGDTASQYMQQLFRSLMFQSQSPGFPFFPFMAPPPPPQQAANPEKPPLVSPPSHRLNPMAVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACDHCSARFTLRSNMERHVKQQHPQFYAQRQRNGHHVMRGRGASNAAAAAAAAAAAAAVMGHGGASAGSNSSAAAANHHHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLANPAALHNGVQANGQSQSLAMDDDEPKLVIDEDENEHEHEVPEEVDDFEEDEDEEELELEEPEEEAEVEAEANQAREEFDEEDEEEEELAKPLDQPANEAAQKMAETILEQAIKAGKPSRSPSIEPPPANPSQTTTTTSMQEPQATPAATPTPTTTTTPTNPSSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRREAEREKERERELERERERERELELERERERELEKEKERERQQLIQKLAAQMNAAAAAAAGAAGGPLGDAMAGGDLPYKCHLCEGSFAERLQCLEHIKQAHAHEFALLLAKGAIENECLDPQQAANPNPNPGQQQSAAHSDDEGLASNGGSSRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVASPPNTPLPVPAVPQSHNNNQNSCHNNNNTNSSSKLGLKLPKLHELLDKASEWRASRLGEHKENLGEATPSGGGAVAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00494606;
90% Identity: iTF_00494606; iTF_00529779; iTF_00512223;
80% Identity: -