Basic Information

Insect: Drosophila kurseongensis
Gene Symbol: RREB1
Assembly: GCA_018153305.1
Location: JAECXX010000141.1:1858682-1865221[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0051 0.38 11.3 0.6 1 21 242 262 242 264 0.96

2 12 0.00029 0.022 15.2 0.2 1 23 274 296 274 296 0.98

3 12 1.8 1.4e+02 3.2 3.7 2 19 543 560 543 562 0.97

4 12 0.0077 0.57 10.7 0.1 1 23 714 736 714 736 0.97

5 12 1.1e-05 0.0008 19.7 0.7 1 23 746 768 746 768 0.99

6 12 0.00072 0.054 13.9 2.0 1 23 774 797 774 797 0.97

7 12 0.0027 0.2 12.1 2.1 1 23 1075 1098 1075 1098 0.95

8 12 7.5e-05 0.0056 17.0 0.3 2 23 1470 1491 1469 1491 0.97

9 12 0.13 9.4 6.9 6.3 1 23 1497 1520 1497 1520 0.97

10 12 5.5 4.1e+02 1.7 1.7 1 23 1633 1656 1633 1656 0.82

11 12 0.0074 0.55 10.8 0.5 3 23 1718 1738 1716 1738 0.96

12 12 0.0056 0.41 11.1 5.7 1 23 1744 1766 1744 1766 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0051	0.38	11.3	0.6	1	21	242	262	242	264	0.96
2	12	0.00029	0.022	15.2	0.2	1	23	274	296	274	296	0.98
3	12	1.8	1.4e+02	3.2	3.7	2	19	543	560	543	562	0.97
4	12	0.0077	0.57	10.7	0.1	1	23	714	736	714	736	0.97
5	12	1.1e-05	0.0008	19.7	0.7	1	23	746	768	746	768	0.99
6	12	0.00072	0.054	13.9	2.0	1	23	774	797	774	797	0.97
7	12	0.0027	0.2	12.1	2.1	1	23	1075	1098	1075	1098	0.95
8	12	7.5e-05	0.0056	17.0	0.3	2	23	1470	1491	1469	1491	0.97
9	12	0.13	9.4	6.9	6.3	1	23	1497	1520	1497	1520	0.97
10	12	5.5	4.1e+02	1.7	1.7	1	23	1633	1656	1633	1656	0.82
11	12	0.0074	0.55	10.8	0.5	3	23	1718	1738	1716	1738	0.96
12	12	0.0056	0.41	11.1	5.7	1	23	1744	1766	1744	1766	0.99

Sequence Information

Coding Sequence: ATGCTCGCCGCACAGCAGCAGCACAACAACAGCACGGCGGAGTCGGAGATGGAGCGCCAGCGGCGGGACTCCACCACCTCGGAGTCCTCCCTGGAGCACCTGGACCTGGGTCGCACGCCCAAGAAACTGGCGGGCACCGGCGGCTCCACTCAGACCACATCCACTCCCCACGAACTGGTGGTCACATCGCGCAAGCGCAAACTGCGCCAGTTGCAACAGCACCAGCCCTTGAGTCACATGCAGCAGGATCTGCTCACTGACGAGGAGGAGGAGGAGGAGGAGGATAGGGATGGGGACGCGGAGGAGCAGGTGGCCGCCACCGGGGCCAGGAGTCTGGGGCGCCACAAGCAGCGACGCAGTGGCGCCACCACCCAGGCCTCCATTGTGGTGGACTACAGCAGTGGCGATGCCAGTTCGCTGCGCAAGAAGTTCCGCCTCAATCGCTCCGCCGGCAGTCTCTCGGAATCGGGATTCGTGGACGCCAGCAGCACGGCGCACAGTAGTGGCTATCTGGGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTCCTCGCCCCAGGGACTGTGCCTCTCCAGCGGCGAGTCGGGAATCGGGGCCGGGGACGAGCACATGAAGTACGTGTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCCGGTGCCACAATTACGCCAACGGCGACACGGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCATCCGCCTCGTCTCTGGACAGACACGTGCTAGTCCACACGGGCGAACGACCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCGCACAAGGCTAACAACAATCTCAAGGATTTGGTGGAGCTGGAGGACGACCAGGATGAGGAGGCGTCGGAGAAGAGGCATCTGCGGACGACCATTAACAACAACATCATAGATAGGGAAACGCAGGAGGAGATCGAGGAGGAGGACGATGCGGATGTGGCCATGCTGACCAGCACACCGGATGTGGCCACCCTGCTGGCCGGAGCCAGTGCATCCGGCGCAGCCTCGCGCTCGCCCTCACCCTCGCCATCCGACGATCACGGCCTGCTCCTCAGCTGTCCCGCCTGCGGAGCCTCCGACTTCGAGACCCTGCCCGCCTTGTGCGCCCACTTGGATGCGCGCCACTCGGACATCCCGGCCAAGTGCCGCGACTGCGAGGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCCCACTGCTGCCGCGGTCCATCCCTGGGCCTCGGCGGGATGCCTCCACTGTTGGGAGCCAGCAGCTCGCCGCTGCACGACGAGGAGCCCGAGGATGTGGACAGGGAGGAGGAGGAGGAGGAGGAGGATCGCGACCGAAAGGAGCGCATGCCGCACCAGGGCGAGGACTTCTTCCACCAGCTGTACCTCAGGCAGAAGGCGGCCGGCGGAGCAGCCAGTGGCGGTGGATCGGCCATCTCGCATCCCCCCTCCCCCATCAAACACGAGCCGGCGGACAGCAAGGACCTGGCCGACATCCAGAGCATCCTGAACATGACCAGCTCCAGCTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAGTACAGCCTGGACGGGCGGGACCTGGAGGAGGAGGCCCAGGACGCGTTCACCTCGGAGTTCCGCCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCTCGGCGGTGTTCCCCAACCTGCGTGCCCTCAAGGGCCACAACCGGGTGCACCTGGGTGCAGTGGGTCCCGCCGGTCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGCGACCGACCCTACGAGTGCGCCGTCTGCAACTACGCCTTTACCACCAAGGCCAACTGCGAGCGGCACCTGCGCAACCGGCACGGGAAGACCAGTCGCGAGGAGGTGAAGCGGGCCATCGTCTACCACCCGGCGGAGGATGCCAACGGCTGCGAGGACGGCAAGTCGCGTCTGGGCGAGGACCTGGCCGACATGAGTTTCCGCTCGATCAGTCCCACACCGCCGCCGCCACCAGCTCCTCCGATCTCGGAGAGCCCCGTCTCCGTCTCCGCCGGCTGCCAGCTGAAGCACATGCTCCTGGGCGAGAGCCACCTGGCTGCGCCAGTGGTGCAGCAGCAGCCCCCCTCGAAGATCCAGGTCAAGAGCCTGGACCAGCTGGTGGACAAGAAGCCGTCGGTCTCTGAGGCTGCCCATCATCAGCAGCAGGAGAAGGGCCTGGACTTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCCACGGCAGGAGCACCGGCCACGCCCTCGGTCAGTCCGCCCATGGCCATGCCGACCGTGGTGGCTCCTCCAGTTGGCCAGGCCACTCCCGATCTGGCCGCCGCCCTGGAGCAGCAGCAGTTGCTCCTCGCCCAGCAGCAACTCTTCGGCGTGGGTGGAGATACCGCCTCGCAGTACATGCAGCAGCTGTTCCGCAGCCTGATGTTCCAGTCGCAGTCGCCGGGATTCCCCTTCTTCCCCTTCATGGCCCCGCCCCCGCCGCCGCAGCAGGCGGCCAATCCGGAGAAGCCACCGCTGGTGAGTCCGCCCAGCCACCGGCTGAATCCCATGGCCGTCGGAGTGGGCGTGCCAGTGCCTCCGGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTTCTGATGCCCAAGCAGAAGCAGCGGCGCTACCGCACCGAGCGCCCCTTCGCCTGCGACCACTGCTCGGCGAGATTCACCCTGCGCTCGAACATGGAGCGCCACGTGAAGCAGCAGCACCCGCAGTTCTACGCCCAGCGCCAGAGGAATGGCCACCACGTGATGAGGGGCAGAGGTGCCTCCAATGCCGCCGCCGCCGCCGCGGCCGCCGCAGCAGCTGCAGCCGTGATGGGACATGGCGGCGCCTCCGCCGGCTCCAACTCATCCGTCACCGGAGCCAACCACCACCACGGCCACGCCCCCATCTCGGAGCAGGTGAAGTACGCCATTCTGGCGCAGCAGCTGAAGGCCCACAAGAACACCGACCTCCTGCAGCAGGCCCTGGCCCACGGCTCCAGCAGCGTGGCCGGCAATCCCCTCCTGCACTTCGGCTACCCGCTGACCAACCCCGCTGCCCTGCACAACGGCGTCCAGGGGAACGGCCAGAGCCAGTCACTGGCCATGGACGACGACGAGCCCAAGCTGGTCATCGACGAGGACGAGAACGAGCACGAGCACGAGGTGCCGGAGGAGGTGGACGACTTCGAGGAGGACGAGGACGAGGAGGAGCTGGAGCTGGAGGAGCCGGAGGAGGAGGCGGAAGCAGAAGCGGAAGCCAACCACGCTCGTGAGGAGTTCGAGGAGGAGGATGATGAGGAGGAGGAGCTGGCCAAGCCATTGGACCAGCCAGCCAACGAGGCGGCCCAGAAAATGGCCGAGACCATCTTGGAGCAGGCCATCAAGGCGGGCAAGCCCTCGAGGAGTCCCTCCATCGAGCCACCGCCAGCCAATCCCTCCCAGACGACCACCACCAGCATGCAGGAGCCACAGACCACACCCGCAGCCACTCCCACACCCACCAACCCCAGCAGTCTGAAGACCATGATCGCCCAGGCCGAGTCCGTGGGCAAGTCCCTTAAAGAGGTGGCCAGCTCGCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCAGTGGCCAAGCTTGTGGACAACGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGCCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGGAGCGCCAGCGAGAGCAACAACAGCGGCACCGAGGACGTCACGAGCAGCAGCTCCGGCTCCGAACCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAACCGCGTCTCCTGCCCCTACTGCCAGCGGATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACGAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTGGAGTCGGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAACCCATCCCGGTGCCCAAGTCCGTGGAGGAGATCGAGCTGGAGGAGCAGCGCCGCCGCCGCGAGGCGGAGCGGGAGAAGGAGCGCGAGCGGGAGCTGGAGCGGGAGCGCGAGCGCGAGAGGGAGCTGGAGCTGGAGCGGGAGCGCGAGCTGGAGAAGGAGAAGGAGCGGGAGCGACAGCAGCTCATCCAGAAGCTGGCGGCCCAGATGAATGCCGCCGCCGCTGCCGCAGCTGGAGCAGCTAGCGGTCCGCTCGGGGATGCAATGGCTGGCGGGGATCTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTCGCGGAGCGGCTGCAGTGCCTGGAGCACATCAAGCTGGCCCACGCCCACGAGTTCGCCCTGCTGCTGGCCAAGGGGGCCATCGAGAACGAGTGCCTGGATCCCCAGCAGGCCGCCCATCCCAATCCCGCCCAGCAGTCGGCGGCCCACTCCGACGACGAGGGCCTGGCCTCCAACGGCGGCGGCAGCCGGGGCAAGTACCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACCGAGGACCTGCGTCGCCACATGCGCACCCACTCCGGCGAGCGGCCCTTCCAGTGCGAAACCTGCCTGCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACGGGCCCACAACGGCGACAATCCGGGCTCCGACTGCTCCGACGACGAGCAGGTGGCCAGTCCGCCCAGCACCCCCCTCCCCGTGCCCGCCGTGCCCCAGTCGCACAACAACAACCAGAACAGCTGCCACAACAACAACAATACCAACTCCAGCTCCAAGCTGGGCCTGAAGCTGCCCAAGCTCCACGAGCTGCTGGACAAGGCCAGCGAGTGGCGGGCCAGTCGGCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCCACGCCCTCGAGCGGAGGCGCCGTCGCCGGATCGGACCTCATCGGCAACCTGCTGGGCATCAGCGACCAGGGCATCCTCAACAAGCTCCTCTCCTCCGCCGACGAGGCGGCCAAGCTGCTCGGCGTGGACAACAAGTAG
Protein Sequence: MLAAQQQHNNSTAESEMERQRRDSTTSESSLEHLDLGRTPKKLAGTGGSTQTTSTPHELVVTSRKRKLRQLQQHQPLSHMQQDLLTDEEEEEEEDRDGDAEEQVAATGARSLGRHKQRRSGATTQASIVVDYSSGDASSLRKKFRLNRSAGSLSESGFVDASSTAHSSGYLGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSPQGLCLSSGESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSHKANNNLKDLVELEDDQDEEASEKRHLRTTINNNIIDRETQEEIEEEDDADVAMLTSTPDVATLLAGASASGAASRSPSPSPSDDHGLLLSCPACGASDFETLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGPSLGLGGMPPLLGASSSPLHDEEPEDVDREEEEEEEDRDRKERMPHQGEDFFHQLYLRQKAAGGAASGGGSAISHPPSPIKHEPADSKDLADIQSILNMTSSSSSFLRNFEQSVNTPSSSQYSLDGRDLEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDANGCEDGKSRLGEDLADMSFRSISPTPPPPPAPPISESPVSVSAGCQLKHMLLGESHLAAPVVQQQPPSKIQVKSLDQLVDKKPSVSEAAHHQQQEKGLDFSMDVLDLSKKPTAGAPATPSVSPPMAMPTVVAPPVGQATPDLAAALEQQQLLLAQQQLFGVGGDTASQYMQQLFRSLMFQSQSPGFPFFPFMAPPPPPQQAANPEKPPLVSPPSHRLNPMAVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACDHCSARFTLRSNMERHVKQQHPQFYAQRQRNGHHVMRGRGASNAAAAAAAAAAAAAVMGHGGASAGSNSSVTGANHHHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLTNPAALHNGVQGNGQSQSLAMDDDEPKLVIDEDENEHEHEVPEEVDDFEEDEDEEELELEEPEEEAEAEAEANHAREEFEEEDDEEEELAKPLDQPANEAAQKMAETILEQAIKAGKPSRSPSIEPPPANPSQTTTTSMQEPQTTPAATPTPTNPSSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRREAEREKERERELERERERERELELERERELEKEKERERQQLIQKLAAQMNAAAAAAAGAASGPLGDAMAGGDLPYKCHLCEGSFAERLQCLEHIKLAHAHEFALLLAKGAIENECLDPQQAAHPNPAQQSAAHSDDEGLASNGGGSRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCETCLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVASPPSTPLPVPAVPQSHNNNQNSCHNNNNTNSSSKLGLKLPKLHELLDKASEWRASRLGEHKENLGEATPSSGGAVAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00494606;
90% Identity: iTF_00588365;
80% Identity: -