Basic Information

Insect: Drosophila carrolli
Gene Symbol: RREB1
Assembly: GCA_018152295.1
Location: JAECXJ010000002.1:3785732-3792321[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0052 0.39 11.3 0.6 1 21 242 262 242 264 0.96

2 12 0.0003 0.022 15.2 0.2 1 23 274 296 274 296 0.98

3 12 1.8 1.4e+02 3.2 3.7 2 19 540 557 540 559 0.97

4 12 0.0078 0.59 10.7 0.1 1 23 711 733 711 733 0.97

5 12 1.1e-05 0.00082 19.7 0.7 1 23 743 765 743 765 0.99

6 12 0.00073 0.055 13.9 2.0 1 23 771 794 771 794 0.97

7 12 0.0027 0.21 12.1 2.1 1 23 1076 1099 1076 1099 0.95

8 12 7.6e-05 0.0058 17.0 0.3 2 23 1479 1500 1478 1500 0.97

9 12 0.13 9.7 6.9 6.3 1 23 1506 1529 1506 1529 0.97

10 12 6.8 5.2e+02 1.4 2.0 1 23 1642 1665 1642 1665 0.83

11 12 0.0074 0.56 10.8 0.5 3 23 1728 1748 1726 1748 0.96

12 12 0.0012 0.093 13.2 4.8 1 23 1754 1776 1754 1776 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0052	0.39	11.3	0.6	1	21	242	262	242	264	0.96
2	12	0.0003	0.022	15.2	0.2	1	23	274	296	274	296	0.98
3	12	1.8	1.4e+02	3.2	3.7	2	19	540	557	540	559	0.97
4	12	0.0078	0.59	10.7	0.1	1	23	711	733	711	733	0.97
5	12	1.1e-05	0.00082	19.7	0.7	1	23	743	765	743	765	0.99
6	12	0.00073	0.055	13.9	2.0	1	23	771	794	771	794	0.97
7	12	0.0027	0.21	12.1	2.1	1	23	1076	1099	1076	1099	0.95
8	12	7.6e-05	0.0058	17.0	0.3	2	23	1479	1500	1478	1500	0.97
9	12	0.13	9.7	6.9	6.3	1	23	1506	1529	1506	1529	0.97
10	12	6.8	5.2e+02	1.4	2.0	1	23	1642	1665	1642	1665	0.83
11	12	0.0074	0.56	10.8	0.5	3	23	1728	1748	1726	1748	0.96
12	12	0.0012	0.093	13.2	4.8	1	23	1754	1776	1754	1776	0.99

Sequence Information

Coding Sequence: ATGCTCGCCGCACAGCAGCAGCACAACAACAGCACGGCGGAGTCGGAGATGGAGCGCCAGCGGCGGGACTCCACCACCTCGGAGTCCTCCCTGGAGCACCTCGACCTGGGTCGCACGCCCAAGAAACTGGGGGGCACCGGCGGCTCCACTCAGACCACATCCACTCCCCACGAACTGGTGGTCACATCGCGCAAGCGCAAACTGCGTCAGTTGCAACAGCACCAGCCCTTGAGTCACATGCAGCAGGATCTGCTCACTGACGAGGAGGAGGAGGAGGAGGAGGATAGGGATGGGGACGCGGAGGAGCAGGTGGCCGCCACTGGGGCCAGGAGCCTGGGGCGCCACAAGCAGCGACGCAGTGGCGCCACCACGCAGGCCTCCATTGTGGTGGACTACAGCAGCGGCGATGCCAGTTCGCTGCGCAAGAAGTTCCGCCTCAATCGCTCCGCCGGCAGTCTCTCGGAATCGGGATTCGTGGACGCCAGCAGCACGGCGCACAGTAGTGGCTATCTGGGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTCCTCGCCCCAGGGACTGTGCCTCTCCAGCGGCGAGTCGGGAATCGGGGCCGGGGACGAGCACATGAAGTACGTGTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCCGGTGCCACAATTACGCCAACGGCGACACGGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCATCCGCCTCGTCTCTGGACAGACACGTGCTGGTCCACACGGGCGAACGACCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAACTCGCACAAGGCTAACAACAATCTCAAGGATTTGGTGGAGCTGGAGGACGACCAGGATGAGGAGGCGTCGGAGAAGAGGCGTCTGCGGACGACCATCAACAACAACATCATAGATAGGGAAACGCAGGAGGAGATCGAGGAGGAGGACGATGCGGATGTGGCCATGCTGACCAGCACACCGGATGTGGCCACCTTGCTGGCCGGAGCCAGTGCATCCGGCGCAGCCTCCCGCTCGCCCTCACCCTCGCCATCCGACGATCACGGCCTGCTCCTCAGCTGTCCCGCCTGCGGAGCCTCCGACTTCGAGACCCTGCCCGCCTTGTGCGCCCACCTGGATGCGCGCCACTCGGACATCCCGGCCAAGTGCCGCGACTGCGAGGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCCCACTGCTGCCGCGGTCCATCCCTGGGCCTCGGCGGGATGCCTCCACTGTTGGGAGCCAGCAGCTCGCCGCTGCACGACGAGGAGCCCGAGGATGTGGACAGGGAGGAGGAGGAGGAGGAGGAGGATCGCGACCGCAAGGAGCGCATGCCGCACCAGGGCGAGGACTTCTTCCACCAGCTGTACCTCAGGCAGAAGGCGGCCAGCGGAGCAGCCAGTGGCGGTGGATCCGCCATCTCGCATCCCCCCTCCCCCATCAAACACGAGCCGGCGGACAGCAAGGACCTGGCCGACATCCAGAGCATCCTGAACATGACCAGCTCCAGCTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAGTACAGCCTGGACGGGCGTGACCTGGAGGAGGAGGCCCAGGACGCGTTCACCTCGGAGTTCCGCCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCTCGGCGGTGTTCCCCAACCTGCGTGCCCTGAAGGGCCACAACCGGGTGCACCTGGGTGCAGTGGGTCCCGCCGGTCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGCGACCGACCCTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGCGAGCGGCACCTGCGCAACCGGCACGGGAAGACCAGTCGCGAGGAGGTGAAGCGGGCCATCGTCTACCACCCGGCGGAGGATGCCAACGGCTGCGAGGACGGCAAGTCGCGTCTGGGCGAGGACCTGGCCGACATGAGCTTCCGCTCGATCAGTCCCACGCCGCCGCCGCCACCAGCTCCTCCGATCTCGGAGAGCCCCGTCTCCGTCACCGCCGGCTGCCAGCTGAAGCACATGCTCCTGGGCGAGAGCCACCTGGGTGCGCCAGTGGTGCAGCAGCAGCCCCCCTCGAAGATCCAGGTCAAGAGCCTGGACCAGCTGGTGGACAAGAAGCCGTCGGTCTCCGATGCTGCCCATCATCAGCAGCAGGAGAAGGGCCTGGACTTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCCACGGCAGGAGCACCGGCCACGCCCTCGGTCAGTCCGCCCATGGCCATGCCGCCCGTGGTGGCACCTCCCGTTGGCCCAGCCACTCCCGATCTGGCCGCCGCCCTGGAGCAGCAGCAGTTGCTCCTGGCCCAGCAGCAACTATTCGGCGTGGGTGGAGATACCGCCTCGCAGTACATGCAGCAGCTGTTCCGCAGCCTGATGTTCCAGTCGCAGTCGCCGGGATTCCCCTTCTTCCCCTTCATGGCCCCGCCCCCGCCGCCGCAGCAGGCGGCCAATCCGGAGAAGCCACCGCTGGTGAGTCCGCCCAGCCACCGGCTGAATCCCATGGCCGTCGGAGTGGGCGTGGGCGTGGGCGTGCCAGTGCCTCCGGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGCCCAAGCAGAAGCAGCGTCGCTACCGCACCGAGCGCCCCTTCGCCTGCGACCACTGCTCGGCGAGATTCACCCTGCGCTCGAACATGGAGCGCCATGTGAAGCAGCAGCACCCGCAGTTCTACGCCCAGCGCCAAAGGAATGGCCACCACGTGATGAGGGGCAGAGGTGCCTCCAATGCCGCCGCCGCCGCCGCTGCCGCCGCAGCAGCTGCAGCCGTGATGGGACATGGCGGCGCCTCCGCCGGCTCCAACTCATCGGCCGCCGCCGCCAACCACCACCACGGCCACGCCCCCATCTCGGAGCAGGTGAAGTACGCCATTCTGGCGCAGCAGCTGAAGGCCCACAAGAACACCGATCTCCTGCAGCAGGCCCTGGCCCACGGCTCCAGCAGCGTGGCCGGCAATCCCCTCCTGCACTTCGGCTACCCGCTGGCCAACCCCGCTGCCCTGCACAACGGCGTCCAGGGGAACGGCCAGAGCCAGTCCCTGGCCATGGACGACGACGAGCCCAAGCTGGTCATCGACGAGGACGAGAACGAGCACGAGCACGAGCACGAGGTGCCCGAGGAGGTGGACGACTTCGAGGAGGACGAGGACGAGGAGGAGCTGGAGCTGGAGGAGCCGGAGGAGGAGGCGGAAGTGGAAGCGGAAGCCAACCAGGCTCGTGAGGAGTTCGAGGAGGATGATGAAGAGGAGGAGGAGCTGGCCAAGCCATTGGACCAGCCAGCCAACGAGGCGGCCCAGAAAATGGCCGAGACCATCTTGGAGCAGGCCATCAAGGCGGGCAAGCCCTCGAGGAGTCCCTCCATCGAGCCACCGCCGGCCAATCCCTCCCAGACGACCACCACCAGCATGCAGGAGCCACAGGCCACACCCGCAGCCACTCCCACTCCCTCGACCACGACCACACCCACCAACCCCAGCAGTCTGAAGACCATGATCGCCCAGGCCGAGTCCGTGGGCAAGTCCCTTAAGGAGGTGGCCAGCTCGCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGGAGCGCCAGCGAGAGCAACAACAGCGGCACCGAGGACGTCACGAGCAGCAGCTCCAGCTCGGAACCAAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAACCGCGTCTCCTGCCCCTACTGCCAGCGGATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACGAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTGGAGTCTGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCCATCCCGGTGCCCAAGTCCGTGGAGGAGATCGAGCTGGAGGAGCAGCGCCGCCGCCGCGAGGCGGAGCGGGAGAAGGAGCGCGAGCGGGAGCTGGAGCGAGAGCGCGAGCGGGAGAGGGAGCTGGAGCTGGAGCGGGAGCGCGAGCTGGAGAAGGAGAAGGAGCGGGAGCGGCAGCAGCTCATCCAGAAGCTGGCGGCCCAGATGAATGCCGCCGCCGCTGCCGCAGCTGGAGCAGCTGGCGGTCCGCTCGGGGATGCAATGGCTGGCGGGGATCTGCCCTACAAGTGCCATCTGTGCGAGGGCTCCTTCGCGGAGCGGCTGCAGTGCCTGGAGCACATCAAGCAGGCCCACGCCCACGAGTTCGCCCTGCTGCTGGCCAAGGGGGCCATCGAGAACGAGTGCCTGGATCCCCAGCAGGCCGCCAATCCCAATCCCGGCCAACAGCAGTCGGCGGCCCACTCCGACGACGAGGGCCTGGCCTCCAACGGCGGCGGCAGCCGGGGCAAGTACCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACCGAGGACCTGCGTCGCCACATGCGCACCCACTCCGGCGAGCGGCCCTTCCAGTGCGACATCTGCCTGCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACGGGCCCACAACGGCGACAATCCGGGCTCCGACTGCTCCGATGACGAACAGGTGGCCAGTCCGCCCAGCACCCCCCTCCCCGTGCCCGCCGTGCCCCAGTCGCACAACAACAACCAGAACAGCTGCCACAATAACAACAACACCAACTCCAGCTCCAAGCTGGGTCTGAAGCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCCAGCGAGTGGCGGGCCAGTCGGCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCCACGCCCTCGGGCGGAGGAGCCGTCGCTGGATCGGACCTCATCGGCAACCTGCTGGGCATCAGCGACCAGGGCATCCTCAACAAGCTCCTCTCCTCCGCCGACGAGGCGGCCAAGCTGCTCGGCGTGGACAACAAGTAG
Protein Sequence: MLAAQQQHNNSTAESEMERQRRDSTTSESSLEHLDLGRTPKKLGGTGGSTQTTSTPHELVVTSRKRKLRQLQQHQPLSHMQQDLLTDEEEEEEEDRDGDAEEQVAATGARSLGRHKQRRSGATTQASIVVDYSSGDASSLRKKFRLNRSAGSLSESGFVDASSTAHSSGYLGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSPQGLCLSSGESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSHKANNNLKDLVELEDDQDEEASEKRRLRTTINNNIIDRETQEEIEEEDDADVAMLTSTPDVATLLAGASASGAASRSPSPSPSDDHGLLLSCPACGASDFETLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGPSLGLGGMPPLLGASSSPLHDEEPEDVDREEEEEEEDRDRKERMPHQGEDFFHQLYLRQKAASGAASGGGSAISHPPSPIKHEPADSKDLADIQSILNMTSSSSSFLRNFEQSVNTPSSSQYSLDGRDLEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDANGCEDGKSRLGEDLADMSFRSISPTPPPPPAPPISESPVSVTAGCQLKHMLLGESHLGAPVVQQQPPSKIQVKSLDQLVDKKPSVSDAAHHQQQEKGLDFSMDVLDLSKKPTAGAPATPSVSPPMAMPPVVAPPVGPATPDLAAALEQQQLLLAQQQLFGVGGDTASQYMQQLFRSLMFQSQSPGFPFFPFMAPPPPPQQAANPEKPPLVSPPSHRLNPMAVGVGVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACDHCSARFTLRSNMERHVKQQHPQFYAQRQRNGHHVMRGRGASNAAAAAAAAAAAAAVMGHGGASAGSNSSAAAANHHHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLANPAALHNGVQGNGQSQSLAMDDDEPKLVIDEDENEHEHEHEVPEEVDDFEEDEDEEELELEEPEEEAEVEAEANQAREEFEEDDEEEEELAKPLDQPANEAAQKMAETILEQAIKAGKPSRSPSIEPPPANPSQTTTTSMQEPQATPAATPTPSTTTTPTNPSSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRREAEREKERERELERERERERELELERERELEKEKERERQQLIQKLAAQMNAAAAAAAGAAGGPLGDAMAGGDLPYKCHLCEGSFAERLQCLEHIKQAHAHEFALLLAKGAIENECLDPQQAANPNPGQQQSAAHSDDEGLASNGGGSRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVASPPSTPLPVPAVPQSHNNNQNSCHNNNNTNSSSKLGLKLPKLHELLDKASEWRASRLGEHKENLGEATPSGGGAVAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00588365; iTF_00529779; iTF_00512223;
90% Identity: iTF_00588365;
80% Identity: -