Dfuy004174.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila fuyamai
Gene Symbol
RREB1
Assembly
GCA_018153365.1
Location
JAECXW010000062.1:19020556-19027095[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0051 0.4 11.3 0.6 1 21 241 261 241 263 0.96
2 12 0.00029 0.023 15.2 0.2 1 23 273 295 273 295 0.98
3 12 1.8 1.4e+02 3.2 3.7 2 19 542 559 542 561 0.97
4 12 0.0077 0.6 10.7 0.1 1 23 713 735 713 735 0.97
5 12 1.1e-05 0.00083 19.7 0.7 1 23 745 767 745 767 0.99
6 12 0.00072 0.056 13.9 2.0 1 23 773 796 773 796 0.97
7 12 0.0027 0.21 12.1 2.1 1 23 1077 1100 1077 1100 0.95
8 12 7.5e-05 0.0058 17.0 0.3 2 23 1476 1497 1475 1497 0.97
9 12 0.13 9.8 6.9 6.3 1 23 1503 1526 1503 1526 0.97
10 12 6.7 5.2e+02 1.4 2.0 1 23 1641 1664 1641 1664 0.83
11 12 0.0073 0.57 10.8 0.5 3 23 1727 1747 1725 1747 0.96
12 12 0.0012 0.094 13.2 4.8 1 23 1753 1775 1753 1775 0.99

Sequence Information

Coding Sequence
ATGCTCGCCGCACAGCAGCAGCACAACAACAGCACGGCGGAGTCGGAGATGGAGCGCCAGCGGCGGGACTCCACCACCTCGGAGTCCTCCCTGGAGCACCTGGACCTGGGTCGCACGCCCAAGAAACTGGGGGGCACCGGCGGCTCCACTCAGACCACATCCACTCCCCACGAACTGGTGGTCACATCGCGCAAGCGCAAACTACGTCAGTTGCAACAGCACCAGCCCTTGAGTCACATGCAGCAGGATCTGCTCACCGACGAGGAGGAGGAGGAGGAGGAGGATAGGGATGGGGACGCGGAGGAGCAGGTGTCCGCCACCGGGACCAGGAGTCTGGGACGCCACAAGCAGCGACGCAGTGGCGCCACCACCCAGGCCTCCATTGTGGTGGACTACAGCAGTGGCGATGCCAGTTCGCTGCGCAAGAAGTTCCGCCTCAATCGCTCCGCCGGCAGTCTCTCGGAATCGGGATTCGTGGACGCCAGCAGCACGGCGCACAGTAGTGGCTATCTGGGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGATCCGGCGGCTCCTCGCCCCAGGGACTGTGCCTCTCCAGCGGCGAGTCGGGAATCGGGGCCGGGGACGAGCACATGAAGTACGTGTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCCGGTGCCACAATTACGCCAACGGCGACACGGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCATCCGCCTCGTCTCTGGACAGACACGTGCTGGTCCACACGGGCGAACGACCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCGCACAAGGCTAACAACAATCTCAAGGATTTGGTGGAGCTGGAGGACGACCAGGATGAGGAGGCGTCGGAGAAGAGGCGTCTGCGGACGACCATCAACAACAACATCATAGATAGGGAAACGCAGGAGGAGATCGAGGAGGAGGACGACGCGGATGTGGCCATGCTGACCAGCACACCGGATGTGGCCACCCTGCTGGCCGGAGCCAGTGCATCCGGCGCAGCCTCGCGCTCGCCCTCACCCTCGCCATCCGACGATCACGGCCTGCTCCTCAGCTGTCCCGCCTGCGGAGCCTCCGACTTCGAGACCCTGCCTGCCTTGTGCGCCCACCTGGATGCCCGCCACTCGGACATCCCGGCCAAGTGCCGCGACTGCGAGGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCCCACTGCTGCCGCGGTCCATCCCTGGGCCTCGGCGGGATGGCTCCACTGTTGGGAGCCAGCAGCTCGCCGCTGCACGACGAGGAGCCCGAGGATGTGGACAGGGAGGAGGAGGAGGAAGAGGAGGATCGCGACCGCAAGGAGCGCATGCCGCACCAGGGCGAGGACTTCTTCCACCAGCTGTACCTCAGGCAGAAGGCGGCCGGCGGAGCAGCCAGTGGCGGTGGATCCGCCATCTCGCATCCCCCCTCCCCCATCAAACACGAGCCGGCGGACAGCAAGGACCTGGCCGACATCCAGAGCATCCTGAACATGACCAGCTCCAGCTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAGTACAGCCTGGACGGGCGGGACCTGGAGGAGGAGGCCCAGGACGCGTTCACCTCGGAGTTCCGCCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCTCGGCGGTGTTCCCCAACCTGCGGGCCCTGAAGGGCCACAACCGGGTGCACCTGGGCGCAGTGGGTCCTGCGGGTCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGCGACCGACCCTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGCGAGCGGCACCTGCGCAACCGGCACGGGAAGACCAGTCGCGAGGAGGTGAAGCGGGCCATCGTCTACCACCCGGCGGAGGACGCGAACGGCTGCGAGGACGGCAAGTCGCGTCTGGGCGAGGACCTGGCCGACATGAGTTTCCGCTCGATCAGTCCCACGCCGCCGCCGCCACCAGCTCCTCCGATCTCGGAGAGCCCCGTCTCCGTCTCCGCCGGCTGCCAGCTGAAGCACATGCTCCTGGGCGAGAGCCACCTGAGTGCGCCAGTGGTGCAGCAGCAGCCCCCCTCGAAGATCCAGGTGAAGAGCCTGGACCAGTTGGTAGACAAGAAGCCGTCGGTCTCCGATGCTGCCCACCATCAGCAGCAGCAGGAGAAGGGCCTGGACTTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCCACGGCAGGAGCACCGGCCACGCCCTCGGTCAGTCCGCCCATGGCCATGCCGCCCGTGGTGGCTCCTCCCGTTGGCCAGGCCACTCCCGATCTGGCCGCCGCCCTGGAGCAGCAGCAGTTGCTCCTCGCCCAGCAGCAGCTCTTCGGCGTGGGTGGAGATACCGCCTCGCAGTACATGCAGCAGCTGTTCCGCAGCCTGATGTTCCAGTCGCAGTCGCCGGGATTCCCCTTCTTCCCCTTCATGGCCCCGCCCCCGCCGCCGCAGCAGGCTGCCAATCCGGAGAAGCCCCCGTTGGTGAGTCCGCCCAGCCACCGGCTGAATCCCATGGCCGTCGGTGTGGGCGTGGGCGTGCCAGTGCCTCCGGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGCCCAAGCAGAAGCAGCGACGCTACCGCACCGAGCGCCCCTTCGCCTGCGACCACTGCTCGGCGAGATTCACCCTGCGCTCGAACATGGAGCGCCACGTGAAGCAGCAGCACCCGCAGTTCTACGCCCAGCGCCAGAGGAATGGCCACCACGTGATGAGGGGCAGAGGTGCCTCCAATGCCGCCGCCGCCGCCGCTGCCGCCGCAGCAGCTGCCGCCGTGATGGGACATGGCGGTGCCTCCGCCGGCTCCAACTCATCCGCCGCCGCCGCCAACCACCACCACGGCCACGCCCCCATCTCGGAGCAGGTGAAGTACGCCATTCTGGCGCAGCAGCTGAAGGCCCACAAGAACACCGATCTCCTGCAGCAGGCCCTGGCCCACGGCTCCAGCAGCGTGGCCGGCAATCCCCTCCTGCACTTCGGCTACCCGCTGGCCAACCCCGCTGCCCTGCACAACGGTGTCCAGGGGAACGGCCAGAGCCAGTCCCTGGCCATGGACGACGACGAGCCCAAGCTGGTCATCGACGAGGACGAGAACGAGCACGAGCACGAGGTGCCCGAGGAGGTGGACGACTTCGAGGAGGACGAGGACGAGGAGGAGCTGGAGCTGGAGGAGCCGGAGGAGGAGGCGGAAGCAGAGGCGGAAGCCAACCAGGCTCGTGAGGAGTTCGAGGAGGAGGATGAGGAGGAGGAGGAGCTGGCCAAGCCATTGGACCAGCCCGCCAACGAGGCGGCCCAGAAAATGGCCGAGACCATCTTGGAGCAGGCCATCAAGGCGGGCAAGCCCTCGAGGAGTCCCTCCATCGAGCCACCGCCAGCCAATCCCTCCCAGACGACCGCCACCAGCATGCAGGAGCCACAGGCCACACCCGCCGCCACTCCCACGCCCACGACCACACCCACCAACCCGAGCAGTCTGAAGACCATGATCGCCCAGGCCGAGTCCGTGGGCAAGTCCCTTAAAGAGGTGGCCAGCTCGCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGGAGCGCCAGCGAGAGCAACAACAGCGGCACCGAGGACGTCACGAGCAGCAGCTCCGGCTCCGAACCGAAGAAGAAGTCCGCCTATAGCCTGGCCCCCAACCGCGTCTCCTGCCCCTACTGCCAGCGGATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACGAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTCGAGTCGGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCCATCCCGGTGCCCAAGTCCGTGGAGGAGATCGAGCTGGAGGAGCAGCGCCGCCGCCGCGAGGCGGAGCGGGAGAAGGAGCGCGAGCGGGAGCTGGAGCGGGAGCGGGAGCGGGAGCGCGAGAGGGAGCTGGAGCTGGAGCGGGAGCGCGAGCTGGAGAAGGAGAAGGAGCGGGAGCGGCAGCAGCTCATCCAGAAGCTGGCGGCCCAGATGAATGCCGCCGCCGCTGCCGCAGCTGGAGCAGCTGGCGGTCCGCTCGGGGATGCAATGGCTGGCGGGGATCTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTCGCGGAGCGGCTGCAGTGCCTGGAGCACATCAAGCAGGCCCACGCCCACGAGTTCGCCCTGCTGCTGGCCAAGGGGGCCATCGAGAACGAGTGCCTGGATCCCCAGCAGGCCGCCAATCCCGCCAATCCCGCCCAGCAGTCGGCGGCCCACTCCGACGACGAGGGCCTGGCCTCCAACGGCGGCGGCAGCCGGGGCAAGTACCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACCGAGGACCTGCGTCGCCACATGCGCACCCACTCCGGCGAGCGGCCCTTCCAGTGCGACATCTGCCTGCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGCGGACGGGCCCACAACGGCGACAACCCGGGCTCCGACTGCTCCGACGACGAGCAGGTGGCCAGTCCGCCCAGCACCCCCCTCCCCGTGCCCGCCGTGCCCCAGACGCACAACAACAACCAGAACAGCTGCCACAACAACAACAATACCAACTCCAGCTCCAAGCTGGGCCTGAAGCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCCAGCGAGTGGCGGGCCAGTCGGCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCCACGCCCTCGGGCGGAGGAGCCGTCGCAGGATCGGACCTCATCGGCAACCTGCTGGGCATCAGCGACCAGGGCATCCTCAACAAGCTCCTCTCCTCCGCCGACGAGGCGGCCAAGCTGCTCGGCGTGGACAACAAGTAG
Protein Sequence
MLAAQQQHNNSTAESEMERQRRDSTTSESSLEHLDLGRTPKKLGGTGGSTQTTSTPHELVVTSRKRKLRQLQQHQPLSHMQQDLLTDEEEEEEEDRDGDAEEQVSATGTRSLGRHKQRRSGATTQASIVVDYSSGDASSLRKKFRLNRSAGSLSESGFVDASSTAHSSGYLGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSGGSSPQGLCLSSGESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSHKANNNLKDLVELEDDQDEEASEKRRLRTTINNNIIDRETQEEIEEEDDADVAMLTSTPDVATLLAGASASGAASRSPSPSPSDDHGLLLSCPACGASDFETLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGPSLGLGGMAPLLGASSSPLHDEEPEDVDREEEEEEEDRDRKERMPHQGEDFFHQLYLRQKAAGGAASGGGSAISHPPSPIKHEPADSKDLADIQSILNMTSSSSSFLRNFEQSVNTPSSSQYSLDGRDLEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDANGCEDGKSRLGEDLADMSFRSISPTPPPPPAPPISESPVSVSAGCQLKHMLLGESHLSAPVVQQQPPSKIQVKSLDQLVDKKPSVSDAAHHQQQQEKGLDFSMDVLDLSKKPTAGAPATPSVSPPMAMPPVVAPPVGQATPDLAAALEQQQLLLAQQQLFGVGGDTASQYMQQLFRSLMFQSQSPGFPFFPFMAPPPPPQQAANPEKPPLVSPPSHRLNPMAVGVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACDHCSARFTLRSNMERHVKQQHPQFYAQRQRNGHHVMRGRGASNAAAAAAAAAAAAAVMGHGGASAGSNSSAAAANHHHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLANPAALHNGVQGNGQSQSLAMDDDEPKLVIDEDENEHEHEVPEEVDDFEEDEDEEELELEEPEEEAEAEAEANQAREEFEEEDEEEEELAKPLDQPANEAAQKMAETILEQAIKAGKPSRSPSIEPPPANPSQTTATSMQEPQATPAATPTPTTTPTNPSSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRREAEREKERERELERERERERERELELERERELEKEKERERQQLIQKLAAQMNAAAAAAAGAAGGPLGDAMAGGDLPYKCHLCEGSFAERLQCLEHIKQAHAHEFALLLAKGAIENECLDPQQAANPANPAQQSAAHSDDEGLASNGGGSRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVASPPSTPLPVPAVPQTHNNNQNSCHNNNNTNSSSKLGLKLPKLHELLDKASEWRASRLGEHKENLGEATPSGGGAVAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00494606;
90% Identity
iTF_00588365;
80% Identity
-