Basic Information

Insect: Drosophila quinaria
Gene Symbol: zfh1
Assembly: GCA_035047525.1
Location: JAWNPO010000470.1:662735-667631[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.2e-05 0.0026 18.5 1.0 1 23 149 171 149 171 0.97

2 15 0.00099 0.079 13.8 1.2 3 23 179 199 177 199 0.94

3 15 0.00011 0.0085 16.8 0.1 1 23 366 388 366 388 0.98

4 15 0.00083 0.067 14.0 0.8 1 23 394 416 394 416 0.98

5 15 3.4e-05 0.0027 18.4 2.0 1 23 448 471 448 471 0.95

6 15 0.00071 0.057 14.3 1.9 1 23 508 530 508 530 0.95

7 15 0.046 3.7 8.6 0.7 1 23 536 559 536 559 0.93

8 15 0.031 2.5 9.1 0.4 3 19 568 584 567 585 0.95

9 15 0.00019 0.015 16.1 5.6 1 23 594 616 594 616 0.97

10 15 0.048 3.9 8.5 1.2 2 23 622 643 621 643 0.96

11 15 1.1e-05 0.00087 20.0 1.0 1 23 652 674 652 674 0.98

12 15 0.0012 0.099 13.5 0.1 3 23 682 702 680 702 0.97

13 15 6.6e-05 0.0053 17.5 0.5 1 23 708 730 708 731 0.95

14 15 0.061 4.9 8.2 0.4 1 23 741 763 741 763 0.97

15 15 0.0035 0.28 12.1 0.1 1 23 1313 1335 1313 1335 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.2e-05	0.0026	18.5	1.0	1	23	149	171	149	171	0.97
2	15	0.00099	0.079	13.8	1.2	3	23	179	199	177	199	0.94
3	15	0.00011	0.0085	16.8	0.1	1	23	366	388	366	388	0.98
4	15	0.00083	0.067	14.0	0.8	1	23	394	416	394	416	0.98
5	15	3.4e-05	0.0027	18.4	2.0	1	23	448	471	448	471	0.95
6	15	0.00071	0.057	14.3	1.9	1	23	508	530	508	530	0.95
7	15	0.046	3.7	8.6	0.7	1	23	536	559	536	559	0.93
8	15	0.031	2.5	9.1	0.4	3	19	568	584	567	585	0.95
9	15	0.00019	0.015	16.1	5.6	1	23	594	616	594	616	0.97
10	15	0.048	3.9	8.5	1.2	2	23	622	643	621	643	0.96
11	15	1.1e-05	0.00087	20.0	1.0	1	23	652	674	652	674	0.98
12	15	0.0012	0.099	13.5	0.1	3	23	682	702	680	702	0.97
13	15	6.6e-05	0.0053	17.5	0.5	1	23	708	730	708	731	0.95
14	15	0.061	4.9	8.2	0.4	1	23	741	763	741	763	0.97
15	15	0.0035	0.28	12.1	0.1	1	23	1313	1335	1313	1335	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCGGCATCCAATGGATACAGCAGCACGCATCTGCTGTCGACTCCGAGTCGGATATGCTGGAAGGCGGCGCTGCCGACAGCGAGGTGACTGCGGCCTATTTGGTGAATGGCAACGCGACCGACGAGGACCTCGACCATATGGCGGCCGAGAATCTCATCTTCATGGCGCGCGACGGACAGCTGAGCGAGATTATCGCTGCCAACGAGTCGGGTGGCGGCACAGTTCTAATCACGGACAGCGGCGTAGCGTACGCCGAGTCCTTCGACGATGACGCCCAGGTGGTCACCGAGGAGATCATTACCGACGACTGGGTGCAGCACCAAGGCGCCGAACGTGTCGAGATTGCTGCGGAGCAAATAGCCGGAAATGTCAATTCGCTGGAGCTACTGGATATGGAGCAGGATGAGTATACGGCGCTGCGTCCATAtccttgtgatttctgtagccGGCGTTTTCGCAAGAAGGCCAGCCTCAACAATCACATGCTGGCCCATCAAAACGATCGTCCGCATCTGTGCAAATTGTGCGGAGCACGATTCTCGCGTCGCGCCGAGCTCATCAGTCACTTCAAGGCACATGCCGAGGCTCAGGATGCAGCGGATGCGGAGGCCGCCGCGGCGGCCTCTATTAAATTTGAGCCACAGCAGCACAGACAAGTCGATGATCATTTCTACGAGCAGGAATGGCCCCTGTATCAGGATCAGGAGCACGAGCATGAACAAATgcaggagcaacagcagcagcagcagcaacaaatggaCCAGGAGCAATTAACCGTGGCCAGCCAGGAGGTGCAACAGGCCAGCTATGCAGCCGTGAGCGATGTGCCCGCTCCAACTACCGCCCGGGGTCGCATTAGTCGCCTCAAGCCCAAGGAGGAGAGCACGCAGTATATTGTGATTGCCGAGAAGCAGCCAACCGACGACATGCAGCAGTTTGTGGACTGCGGAGGCTTGGCGCCAACGCTGCCCGCCAATGCGACGTCAAGCCAAGACGTCGATGAGACAGACAATACGGCGGACAACGGCCAGGCCATGAATGCATCACGTTTCCCCGTGCTGGACGATAGCAAACCCTTTGTGTGCCAGCAATGCGGCTTGGCATTTGCGCGAGAGAAGGCGCTCGTCTCCCATATCAAGAATCATCGCGTGGACTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGATAATCAGAGTCTGCAGGAGCATCAAAAGACACATCAGTTCGAGGAGAGCAATTCAGAGTACGATCCTGCCTCGGCGGGGGATGACAGTGCCACCGAGGAATCGGAGCCGGATCAGCTCTATGGCGACTTCTACTGCAGCGAGTGCGGCATCTCGTTCCACAGGCAGGATCTGCTCCGTCGCCATGCCAAGCAGATGCACAAGCTGGGCATTTCATCCACTGTCAACTCTGTCGATGTGGATGGCAGTGCAGATGCCGATGGTGATGGTGTTGGTGATATCGATGCCGAGAATACCAAAGATGCGCCGCATTGTTGTCATACGTGTGGCAAGTCATTCCCCAGCGCATTGGAGCTGCTCGCCCATGCCGAGATTCATGCCCGTTTCCCGCCATTCAAATGCGTCTTGTGCGGCATTAGCTTTTACGAGGAGCAGGCCATCAAGCGGCATTTGCACGCTCGCCATCCGCACGAGCTCAAGCAAAATTCATGTGTGCTCTGTGGTAAGGAGTGTCGCGATCGCAAGGCGCTGATCAAGCACGCCTGGGATCATTCCCGCGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTTCACAACAAGGCGCGTCTGAAGCGACACATGGCCTCGCATCGCGACAAGTCGGTGGTGTGCGAGGTGTGCCACGAGGAGTTCCCAGACGGACGCACCTTGTCCAATCATCGCCATTCGCATAGCACCACGTCGCCGGGCAAACTGTTTCCTTGCCACGAGTGCGGGAAAACTTTTGGCTCACGGAGCTCACAGCAGATCCACGTGCGCATCCACACGGGCGAACGGCCTTACGGATGTCGCTATTGCTGGAAGGCCTTTGCCGATGGCGGAACGCTGCGCAAGCACGAGAGGATTCACACTGGCGAGAAGCCATATGCCTGCTCCGTCTGTCCGCGTGCGTTTAATCAGCGGGTTGTGCTCAGGGAACACATACGCTCCCATCATTCGGGCTTGGATGAAGTGCGTGGCACGTATCATTGCACCGTCTGCACAGCGGACTTATCCTCATCCAATGAGCTCATACAGCATCTCATTCAACACAGCGACACGAACACAGCCAAACAGCGACAACCGATTACGGGTCCCCGCAAGTACAAGCGTCGACGGAAACTGCAGCCGCATGAGATTGCACACATGCGGGCCGAGCACAAGGATGGCGACGACTATGTCAGCGACATGGATCTCTGCGATCTGGATGTGGAAAACGTGGACGATCTGTTTGACGCGACGGAAGCAACGCCGCCCAAAAAGGAGAAGCGCAAACGCACTGCGGCCAGTCAAGCGAAACCAGCGTCAAACGGCGTCTCAACATCCGCGCCAAGCAACAACGCAACTTCATCAGCTAAATCCGCCAGTGGGAATCAGGATCGCCTGTGGGAGGAGAAATTCTTGCAGgcaaatggcaatggcaatggcaatgccaaCAATCAGTTGAATGATGATGCATTCAAGAACATCTTTCAAATTGATTCGCTGGTGGTGATAAATGATACCACGTTGCAGCCTGTAAGCTCATCCAGTGGAGTCAATGCGTCCAAGACGCGGCGTGGTGTCAAGCACACGCAACAGACGCAACAGTTGCAGacaaaaagcagcaacaacaacaagtcgaCGACTGCAACGACAACCACAGTTGGAGAGGATTGCAGCAAGTCCAGTGCCTCCGTATCATCGAGCAGCCGGAGCAGCAGCCGTAAGAAAGCAGCCAAGTCCACGAAGAACGCGACCAGCACGGCATCCACGTCGAGCAGCTCGCGTCCCCGGATGATACACACGGAAAAGACACGTGTGCCGCCAGAGAATGCGTCGAAGAGGACGCGAGGAAGGTCCTACATCACGAGGACGAGCACCAGCGAGAGCAGCCAGCTGGGTCTGGTCAAGTCGAGTGGCGTTGGCAGCTCCTCGCGCATTGTGGACGACTATGAGATAATATCACCCGCCACACAGCCACCGAACCAGATCAGCTCCAGTCCGCTGCATATcaagcaggagcaggagcagcaccAACAGCGTGGCCCACTCATGTATGATGACACACATCTGCTGATCGATGCGGCCCTGTTGCGCGAGAAGACCTATGAGAAGTTCAATCCCAGCATTGTCAATGATCTGGAGGAGATACTGCGCAGTCCGCTCAAGCATGATCGCAATTCGCGGCTGCGCTTCACCAGCGAATCCTCGACAACGCCACAGTTCCTGCCCGAGGAGGAGCAGAATCTGATTAAGATCGAGCCAACGTCACCGGACTTGCGTGAAATGGTTGAGAGCCAGCAGCGTGTCAGTTCCACGGGACACACAACCATCACCACCACGCCCTCCTCATCATTGTCATCCTCGTCAGCGGCACGCACTTCCCGCCACCTGCGACAGCTCACTGCCGCCTTGAACCAGACTAGGACGGCAGTGAAacgccacagcagcaacaaacaagTTTCTGCCTCCAGTTCCAAGaaatccgcatccgcatcatCCTCGTCGGCAGCATCTGTTGCATCTGTGAGCAAGGCAACCAACTCGTACCTCAGCTATGACGTGGACTCCTACAATGTGGGTGTGGCTGCCAATGCCAACTCATCAGATGTAAGCTCGGGATTCTTTTCCATCTCGGAGGTCGTGTCCGCGGCAGATGCCGCCGATGCAGCCGCCAAGGCAGCGGCGGCCAACAAACCGGAGCGTCGAGCCCGTTGCTATGAGTGCGAAATGTGCTCGGCCAATTTTCCGGATCGCGCCCAGCTGCTGGAGCATGTGCATATACACATCTGA
Protein Sequence: MNNQDYGGIQWIQQHASAVDSESDMLEGGAADSEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANESGGGTVLITDSGVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNVNSLELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAASIKFEPQQHRQVDDHFYEQEWPLYQDQEHEHEQMQEQQQQQQQQMDQEQLTVASQEVQQASYAAVSDVPAPTTARGRISRLKPKEESTQYIVIAEKQPTDDMQQFVDCGGLAPTLPANATSSQDVDETDNTADNGQAMNASRFPVLDDSKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNQSLQEHQKTHQFEESNSEYDPASAGDDSATEESEPDQLYGDFYCSECGISFHRQDLLRRHAKQMHKLGISSTVNSVDVDGSADADGDGVGDIDAENTKDAPHCCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHARHPHELKQNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDEVRGTYHCTVCTADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDGDDYVSDMDLCDLDVENVDDLFDATEATPPKKEKRKRTAASQAKPASNGVSTSAPSNNATSSAKSASGNQDRLWEEKFLQANGNGNGNANNQLNDDAFKNIFQIDSLVVINDTTLQPVSSSSGVNASKTRRGVKHTQQTQQLQTKSSNNNKSTTATTTTVGEDCSKSSASVSSSSRSSSRKKAAKSTKNATSTASTSSSSRPRMIHTEKTRVPPENASKRTRGRSYITRTSTSESSQLGLVKSSGVGSSSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQHQQRGPLMYDDTHLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHDRNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVSSTGHTTITTTPSSSLSSSSAARTSRHLRQLTAALNQTRTAVKRHSSNKQVSASSSKKSASASSSSAASVASVSKATNSYLSYDVDSYNVGVAANANSSDVSSGFFSISEVVSAADAADAAAKAAAANKPERRARCYECEMCSANFPDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579414;
90% Identity: iTF_00533988; iTF_00528970; iTF_00601973; iTF_00586105;
80% Identity: -