Basic Information

Insect: Drosophila limbata
Gene Symbol: zfh1
Assembly: GCA_963924055.1
Location: OZ001352.1:25494629-25498960[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3e-05 0.003 18.5 1.0 1 23 149 171 149 171 0.97

2 15 0.00092 0.093 13.8 1.2 3 23 179 199 177 199 0.94

3 15 0.00033 0.033 15.3 0.1 1 23 362 384 362 384 0.98

4 15 0.00078 0.079 14.1 0.8 1 23 390 412 390 412 0.98

5 15 3.2e-05 0.0032 18.4 2.0 1 23 444 467 444 467 0.95

6 15 0.00066 0.067 14.3 1.9 1 23 502 524 502 524 0.95

7 15 0.043 4.4 8.6 0.7 1 23 530 553 530 553 0.93

8 15 0.029 3 9.1 0.4 3 19 562 578 561 579 0.95

9 15 0.00017 0.018 16.1 5.6 1 23 588 610 588 610 0.97

10 15 0.045 4.6 8.5 1.2 2 23 616 637 615 637 0.96

11 15 1e-05 0.001 20.0 1.0 1 23 646 668 646 668 0.98

12 15 0.0012 0.12 13.5 0.1 3 23 676 696 674 696 0.97

13 15 6.2e-05 0.0062 17.5 0.5 1 23 702 724 702 725 0.95

14 15 0.057 5.7 8.2 0.4 1 23 735 757 735 757 0.97

15 15 0.0033 0.33 12.1 0.1 1 23 1293 1315 1293 1315 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3e-05	0.003	18.5	1.0	1	23	149	171	149	171	0.97
2	15	0.00092	0.093	13.8	1.2	3	23	179	199	177	199	0.94
3	15	0.00033	0.033	15.3	0.1	1	23	362	384	362	384	0.98
4	15	0.00078	0.079	14.1	0.8	1	23	390	412	390	412	0.98
5	15	3.2e-05	0.0032	18.4	2.0	1	23	444	467	444	467	0.95
6	15	0.00066	0.067	14.3	1.9	1	23	502	524	502	524	0.95
7	15	0.043	4.4	8.6	0.7	1	23	530	553	530	553	0.93
8	15	0.029	3	9.1	0.4	3	19	562	578	561	579	0.95
9	15	0.00017	0.018	16.1	5.6	1	23	588	610	588	610	0.97
10	15	0.045	4.6	8.5	1.2	2	23	616	637	615	637	0.96
11	15	1e-05	0.001	20.0	1.0	1	23	646	668	646	668	0.98
12	15	0.0012	0.12	13.5	0.1	3	23	676	696	674	696	0.97
13	15	6.2e-05	0.0062	17.5	0.5	1	23	702	724	702	725	0.95
14	15	0.057	5.7	8.2	0.4	1	23	735	757	735	757	0.97
15	15	0.0033	0.33	12.1	0.1	1	23	1293	1315	1293	1315	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGGACTATGGCGGCATCCAATGGATACAGCAGCACGCATCTGCGGTCGACTCCGAGTCAGATATGCTGGAAAGCGGCGCTGCCGACAGCGAGGTGACTGCGGCCTATTTGGTGAATGGCAATGCAACCGACGAGGACCTCGACCATATGGCGGCCGAGAATCTCATCTTTATGGCGCGAGACGGTCAGCTGAGCGAGATTATCGCTGCCAACGAATCGGGGGGCGGCACAGTTCTAATCACTGACAGCGGCGTTGCATATGCCGAGTCATTCGACGATGACGCACAGGTGGTCACCGAGGAGATCATTACCGATGATTGGGTGCAGCACCAAGGCGCCGAACGTGTCGAAATCGCTGCGGAGCAAATTGCTGGAAATGTCAATTCGCTGGAGCTACTGGATATGGAGCAGGATGAGTATACGGCACTGCGTCCATATCCTTGTGATTTCTGTAGCCGGCGTTTTCGCAAGAAGGCAAGCCTCAACAATCACATGCTGGCGCATCAGAACGATCGTCCGCATCTGTGCAAATTGTGCGGTGCACGATTTTCCCGTCGCGCCGAGCTCATCAGTCATTTCAAGGCACATGCCGAGGCTCAGGATGCTGCCGATGCGGAGGCCGCTGCGGCGgcatcaattaaatttgagcCACAGCAGCATAGACAAGTCGATGATCATTTCTACGAACAGGAATGGCCACTATATCAGGACCAGGATCAGGAACACGAACAAatgcaggagcagcagcagcaacaacaaatggacCAGGAGCAGTTAAGCGTTGCCAGCCAGGAGGTGCAGCAGGCCAGCTATGCAGCAGTAAGCGATGTGCCCGCTCCAATTGCCGCCCGGGGTCGGATAAGTCGCCTCAAGCCCAAGGAGGAGAGCACGCAGTATATTGTGATTGCTGAGAAGCAGACAACCGACGACATGCAACAGTTTGTGGATTGTGGAGGCTTGGCGCCAACGCTGCCTGCCAATGCGACGTCCAGCGTCGTCGATGCCAACAATGCGACAGACAACGGTCAGGCAATGAGTGCATCGCGTTTCCCAGTGCTGGACGATAGCAAACCCTTTGTGTGCCAACAATGTGGCTTGGCATTTGCGCGAGAGAAGGCGCTCGTCTCCCATGTCAAGAATCATCGCGTGGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGATAATCAGAGTCTGCAGGAGCATCAGAAGACACATCAGTTCGAGGAGAGCAACTCTGAGTACGATCCCGCCTCGGCGGGGGACGACAGTGCCACTGAAGAATCGGAGCCAGATCAGCTCTATGGTGACTTCTACTGCAGTGAGTGCGGCATTTCGTTTCACAGGCAGGATCTGCTCCGTCGCCATGCCAAGCAGATGCATAAGATGGGCATGGCGTCCACTGTCAACTCTGTCGATGTGGATGGCAGTGCAGATGCtgatggtgatggtgatgTTGATGCCGAGAATACCAAAGATGCGCCGCATTGCTGTCATACGTGTGGCAAGTCATTCCCCAGCGCATTGGAGCTGCTCGCCCATGCCGAGATTCATGCCCGTTTCCCGCCATTCAAATGCGTCTTGTGTGGCATTAGCTTTTACGAGGAACAGGCCATCAAAAGGCATTTGCACGCTCGTCATCCGCACGAGCTGAAGCCAAATTCATGTGTGCTCTGTGGCAAGGAGTGTCGCGATCGCAAGGCGTTGATCAAACACGCCTGGGATCATTCCCGTGAGAAGTGTCACTCGTGCTCCAAGTGCGGCAAGAACTTTCACAACAAGGCGCGTCTGAAGCGACACATGGCCTCGCATCGCGACAAGTCGGTTGTGTGCGAGGTGTGCCACGAGGAGTTCCCCGACGGACGCACCCTTTCCAATCATCGTCATTCGCACAGCACTACGTCGCCAGGCAAACTGTTTCCCTGCCATGAGTGCGGCAAAACTTTTGGCTCCCGCAGCTCACAGCAGATCCACGTACGCATCCACACGGGCGAAAGACCTTATGGTTGTCGCTATTGCTGGAAGGCCTTCGCCGATGGCGGTACGCTGCGCAAGCACGAGAGGATTCACACTGGCGAGAAGCCATATGCGTGCTCCGTCTGTCCGCGTGCGTTTAATCAGCGTGTTGTGCTTAGGGAACACATACGCTCCCATCATTCGGGATTGGATGCAGTGCGCGGCACGTATCATTGCACCGTCTGCACAGCGGATTTGTCCTCATCCAATGAGCTTATACAGCATCTCATTCAACACAGCGACACGAACACAGCCAAACAGCGACAACCAATTACGGGTCCCCGTAAATACAAGCGTCGAAGGAAACTTCAGCCGCATGAGATTGCACACATGCGTGCGGAGCACAAGGATGGCGACGATTATGTCAGCGACATGGATCTCTGCGACCTGGATGTGGAAAATGTGGACGATCTGTTTGACGCGGCTGAAGCATCGCCACCCAAAAAGGAGAAGCGTAAACGCAATGCTGCCAGTCAAGCGAAACCAGCGTCAAATGGCGTCTCGACTTCCGCgcttaacaacaacacaacttCATCGGTTAAATCCTCCAGTGGGAATCAGGATCGCCTGTGGGAGGAGAAGTTCCTGCAGGCAAatggcaatgccaatgccaataaTCAGTTGAATGATGATGCGTTCAAGAACATCTTTCAAATTGATTCGCTGGTGGTGATAAATGATACCACGCTGCAGCCTGTAAGCTCATCCAGTGGAGTCACTGCGTCCAAGACGCGGCGTGGTGTTAAAAACACGCAACAGTTGCAgacaagcaacagcagcagcaacaagtcaGTGACAGCTGGAGAGGAGTGCAGCAAGTCCAGTGCCTCCGTATCATCAAGCAGTCGGAGCAGCAGCCGTAAGAAAGCAGCCAAGTCCACGAAGAACGCGTCCAGCACGGCATCCACATCGAGCAGCTCGCGTCCACGGATGATTCACACGGAAAAGTCTCGTGTGCCGCCAGAGAATGCGTCGAAGAGGACACGAGGAAGGTCCTACATCACAAGGACGAGCACCAGCGAGAGCAACCAGCTGGGTCTGGTCAAGTCGAGTGGCGTTGGGAGCTCCTCGCGCATTGTGGATGACTATGAGATTATATCACCTGCCACACAGCCACCGAATCAGATCAGCTCCAGTCCGTTGCACATCAAGCAggaacaggagcagcagcaacagcgtgTCCCACTCATGTATGATGACACGCATCTGCTGATCGATGCGGCCCTGTTGCGTGAAAAGGCCTATGAGAAGTTCAATCCCAGCATTGTCAATGATCTGGAGGAGATACTGCGTAGTCCGCTCAAGCATGATCGCAATTCGCGATTGCGCTTCACCAGCGAATCATCGACAACGCCACAGTTCCTGCCCGAGGAGGAGCAGAATCTGATTAAGATCGAGCCAACGTCACCGGACTTGCGTGAAATGGTTGAGAGCCAGCAGCGTGTCAGTTCCACAGGACACACAACCATAACCACGCCCTCAACATCTTCATCCTCGTCAGCGGCACGCACTTCCCGCCACCTGCGACAGCTCACTACCAACTCCGGTTCACGGGCGGCAACGAAACGCcacagcagcagtagcaacaaAACAGTTTCCGCCTCCAGCTCCAAGaaatccgcatccgcatcatCCTCGTCAGCAGCATCTGTGAGCAAAGCAACCAACTCGTACCTCAGCTATGGCGTGGACTCCTACAATGTGAATGTTGCCACCAATGCCAACTCATCGGATGTCAGCTCCGGATTCTTCTCCATCTCGGAGGTCGTCTCAGCTGCCGATGCCGCCGATGCAGCGGCCAAAGCGGCGGCGGCCAACAAACCGGAGCGTCGAGCCCGTTGCTATGAGTGCGAAATGTGCTCGGCCAATTTTCCGGATCGCGCCCAGCTGCTGGAGCATGTGCATATACACATCTGA
Protein Sequence: MNNQDYGGIQWIQQHASAVDSESDMLESGAADSEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANESGGGTVLITDSGVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNVNSLELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAASIKFEPQQHRQVDDHFYEQEWPLYQDQDQEHEQMQEQQQQQQMDQEQLSVASQEVQQASYAAVSDVPAPIAARGRISRLKPKEESTQYIVIAEKQTTDDMQQFVDCGGLAPTLPANATSSVVDANNATDNGQAMSASRFPVLDDSKPFVCQQCGLAFAREKALVSHVKNHRVDSPFECNQCQEMFWDNQSLQEHQKTHQFEESNSEYDPASAGDDSATEESEPDQLYGDFYCSECGISFHRQDLLRRHAKQMHKMGMASTVNSVDVDGSADADGDGDVDAENTKDAPHCCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHARHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCTADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDGDDYVSDMDLCDLDVENVDDLFDAAEASPPKKEKRKRNAASQAKPASNGVSTSALNNNTTSSVKSSSGNQDRLWEEKFLQANGNANANNQLNDDAFKNIFQIDSLVVINDTTLQPVSSSSGVTASKTRRGVKNTQQLQTSNSSSNKSVTAGEECSKSSASVSSSSRSSSRKKAAKSTKNASSTASTSSSSRPRMIHTEKSRVPPENASKRTRGRSYITRTSTSESNQLGLVKSSGVGSSSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQRVPLMYDDTHLLIDAALLREKAYEKFNPSIVNDLEEILRSPLKHDRNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVSSTGHTTITTPSTSSSSSAARTSRHLRQLTTNSGSRAATKRHSSSSNKTVSASSSKKSASASSSSAASVSKATNSYLSYGVDSYNVNVATNANSSDVSSGFFSISEVVSAADAADAAAKAAAANKPERRARCYECEMCSANFPDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579414;
90% Identity: iTF_00585360;
80% Identity: -