Basic Information

Insect: Drosophila rellima
Gene Symbol: zfh1
Assembly: GCA_035043635.1
Location: JAWNMV010000811.1:3407373-3411702[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.9e-05 0.002 18.5 1.0 1 23 149 171 149 171 0.97

2 15 0.00088 0.061 13.8 1.2 3 23 179 199 177 199 0.94

3 15 9.5e-05 0.0067 16.9 0.1 1 23 358 380 358 380 0.98

4 15 0.00071 0.049 14.1 0.8 1 23 386 408 386 408 0.98

5 15 3e-05 0.0021 18.4 2.0 1 23 439 462 439 462 0.95

6 15 0.00063 0.044 14.3 1.9 1 23 499 521 499 521 0.95

7 15 0.041 2.9 8.6 0.7 1 23 527 550 527 550 0.93

8 15 0.028 1.9 9.1 0.4 3 19 559 575 558 576 0.95

9 15 0.00017 0.012 16.1 5.6 1 23 585 607 585 607 0.97

10 15 0.043 3 8.5 1.2 2 23 613 634 612 634 0.96

11 15 9.7e-06 0.00068 20.0 1.0 1 23 643 665 643 665 0.98

12 15 0.0011 0.077 13.5 0.1 3 23 673 693 671 693 0.97

13 15 5.9e-05 0.0041 17.5 0.5 1 23 699 721 699 722 0.95

14 15 0.054 3.8 8.2 0.4 1 23 732 754 732 754 0.97

15 15 0.0031 0.22 12.1 0.1 1 23 1291 1313 1291 1313 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.9e-05	0.002	18.5	1.0	1	23	149	171	149	171	0.97
2	15	0.00088	0.061	13.8	1.2	3	23	179	199	177	199	0.94
3	15	9.5e-05	0.0067	16.9	0.1	1	23	358	380	358	380	0.98
4	15	0.00071	0.049	14.1	0.8	1	23	386	408	386	408	0.98
5	15	3e-05	0.0021	18.4	2.0	1	23	439	462	439	462	0.95
6	15	0.00063	0.044	14.3	1.9	1	23	499	521	499	521	0.95
7	15	0.041	2.9	8.6	0.7	1	23	527	550	527	550	0.93
8	15	0.028	1.9	9.1	0.4	3	19	559	575	558	576	0.95
9	15	0.00017	0.012	16.1	5.6	1	23	585	607	585	607	0.97
10	15	0.043	3	8.5	1.2	2	23	613	634	612	634	0.96
11	15	9.7e-06	0.00068	20.0	1.0	1	23	643	665	643	665	0.98
12	15	0.0011	0.077	13.5	0.1	3	23	673	693	671	693	0.97
13	15	5.9e-05	0.0041	17.5	0.5	1	23	699	721	699	722	0.95
14	15	0.054	3.8	8.2	0.4	1	23	732	754	732	754	0.97
15	15	0.0031	0.22	12.1	0.1	1	23	1291	1313	1291	1313	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGGACTATGGCGGCATCCAATGGATACAGCAGCACGCATCTGCGGTCGACTCCGAGTCTGATATGCTGGAAAGCGGCGCTGCCGACAGCGAGGTGACTGCGGCCTATTTGGTGAATGGCAATGCAACCGACGAGGACCTCGACCATATGGCGGCCGAGAATCTCATCTTTATGGCGCGAGACGGTCAGCTGAGCGAGATTATCGCTGCCAACGAATCGGGCGGCGGCACAGTTCTAATCACTGACAGCGGCGTTGCATACGCCGAGTCATTCGATGATGACGCACAGGTGGTCACCGAGGAGATCATTACCGATGATTGGGTGCAGCATCAAGGCGCCGAACGTGTCGAGATCGCTGCGGAGCAAATTGCTGGAAATGTTAATTCGCTGGAGCTACTGGATATGGAGCAGGATGAGTATACGGCACTGCGACCCTATCCTTGTGATTTCTGTAGCCGGCGTTTTCGCAAAAAGGCAAGCCTCAACAATCACATGCTGGCGCATCAAAACGATCGTCCGCATTTGTGTAAATTGTGCGGAGCAAGATTTTCGCGTCGCGCCGAGCTCATCAGTCACTTTAAGGCACATGCCGAGGCTCAGGATGCAGCCGATGCGGAGGCTGCAGCGGCGGCTTCGATTAAATTTGAGCCACAACAGCACAGACAAGTCGATGATCATTTCTACGAACAGGAATGGCCACTGTATCAGGAGCAGGACCAGGAGCACGATCAAATGCAGGAGCAACAAATGGAGCAGGAGCAGTTAACCGTTGCCAACCAGGAGATGCAACAAGCCAGCTATGCAGCAGTGAGCGATGTGCCCGCTCCAACTGCCGCCCGAGGTCGTATAAGTCGCCTCAAGCCCAAGGAGGAGAGCACGCAGTATATTGTGATTGCTGAGAAGCAGACAACAGATGTCTTGCAACAGTTTGTAGACTGTGAAGGCTTGGCGCCAACGCTGCCTGCCAATGCGACGTCAAGCGACGTCGATGCCAACAATGCGACAGAGAACGGTCAAGCAATGAATGCATCACGTTTCCCAGTACTGGATGATAGCAAACCCTTTGTGTGCCAACAATGTGGCTTGGCATTTGCGCGAGAGAAGGCGCTCGTCTCCCATATCAAGAATCATCGCGTGGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGATAGCCAGAGTCTGCAGGAGCATCAGAAGACACATCAGTTCGAGGAGAGCAATTCAGAGTACGATCCTGCCTCGGCAGGGGATGACAGTGCCAGTGAATCGGAGCCAGATCAGCTCTATGGTGACTTCTACTGTAGTGAGTGCGGCATTTCGTTTCACAGGCAGGACCTGCTCCGTCGCCATGCCAAGCAGATGCATAAGTTGGGCATGGGGAGCGCTGTGGCATCCACGGTCAACTCTGTCGATGTGGATGGCAGTGcagatgctgatgctgatgccgatgccgaGAATACCAAAGATGCGCCGCATTGTTGTCATACGTGTGGAAAGTCATTCCCCAGCGCATTGGAGCTGCTCGCCCATGCCGAGATTCATGCCCGTTTCCCGCCATTCAAATGTGTCTTATGTGGCATAAGCTTTTACGAGGAACAGGCCATCAAAAGGCATTTGCACGCTCGTCATCCGCACGAGCTTAAGCCAAATTCATGTGTGCTCTGTGGCAAGGAGTGTCGCGATCGCAAGGCGTTGATTAAACACGCCTGGGATCATTCCCGTGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTTCACAACAAGGCGCGTCTGAAGCGACACATGGCCTCGCATCGCGATAAGTCGGTGGTGTGCGAGGTGTGCCACGAGGAGTTCCCCGACGGACGCACCCTTTCCAATCATCGTCATTCGCATAGCACAACGTCGCCGGGCAAACTGTTCCCCTGCCATGAATGCGGGAAAACTTTTGGCTCCCGCAGCTCACAGCAGATTCATGTGCGCATCCACACCGGCGAAAGGCCTTACGGTTGTCGCTATTGCTGGAAGGCCTTTGCCGATGGCGGTACGCTGCGCAAGCACGAAAGGATTCACACTGGCGAGAAGCCATATGCCTGCTCCGTTTGTCCCCGTGCGTTTAATCAGCGTGTTGTGCTGAGGGAGCACATACGCTCCCATCATTCTGGATTAGATGCAGTGCGTGGCACGTATCATTGCACCGTCTGCACAGCAGATTTATCCTCATCCAATGAGCTCATACAGCATCTCATTCAACACAGCGACACGAACACAGccaaacaacgacaaccaatTACGGGTCCCCGGAAATACAAACGTCGAAGGAAACTGCAGCCTCATGAAATTGCACACATGCGTGCGGAGCACAAGGATGGCGACGATTATGTCAGCGACATGGATCTCTGCGATCTGGATGTGGAAAATGTGGACGATCTGTTTGATGCGGCGGAAACAACGCCGCCCAAAAGGGAGAAGCGTAAACGCAATGCTGCAGGTCAAACGAAAGCAGCGTCAAATGTCGTCTCAGCATCCGCgctaaacaacaacacaactttATCAGCTAAATCCGCCAATGGCAACCAGGATCGCCTGTGGGAGGAGAAATTCCTGCAGGCAAAtagcaatggcaatgccaacagTCAGTTGAATGATGATGCATTCAAGAACATCTTTCAAATTGATTCGCTGGTGGTAATTAATGATACCACGTTGCAACCTGTTAGCTCATCCAGTACCAGTGGTGCCCCTGCGTCCAAGACGCGGCGCAGCGTCAAAAACACTCAACAGACACAACAGTTGCAGACGAGCAGCAGGAAGTCAAcgacagcagcggcaacaacagggGGTGATGATTGCAGCAAGTCCAGTGCCTCCGTGTCATCAAACAGTCGGAGCAGCAGCCGTAAGAAAACAGCCAAGTCCACAAAGAACGCGGCCAGCACGGCGTCCACATCGAGCAGCTCGCGTCCACGCATGATACACACGGAAAAGTCACGGGTGCCGCCAGAGAATGCGTCGAGGAGGACACGAGGAAGGTCTTATATCACGAGGACGAGTACCAGCGAGAGCAACCAGCTGGGTCTGGTCAAGTCGAGTGGCGTTGGGAGCTCACGCATTGTGGATGACTATGAGATTATATCACCTGCCACACAGCCACCGAATCAGATAAGCTCCAGTCCGTTGCACATTAagcaggaacaggagcagcagcaacagcgtgTGCCACTCATGTATGATGATACGCATCTGCTGATCGATGCGGCCTTGTTGCGTGAGAAGACCTATGAGAAGTTCAATCCCAGCATTGTTAATGACCTGGAGGAGATACTGCGTAGTCCTCTTAAGCATGATCGCAATTCGCGTCTGCGTTTCACCAGCGAATCATCGACAACGCCACAGTTCCTGCCCGAGGAGGAGCAGAATCTTATTAAAATCGAGCCTACGTCACCGGATTTGCGTGAAATGGTTGAGAGCCAGCAGCGTGTGAGTTCCTCAGGACACACAACCATAACGACGCCCTCATCGTCATTCTCGTCAGCGGCACGCACTTCCCGCCACCTGCGACAGCTTACTGCCAACTCCGGTTCAAGGGCGACAACGAAACGccacagcggcaacaaaacAGTTTCCACCTCCAGTTCCAAGAAATCCGCATTATCTTCATCTGCAACGTCTGTAAGCAAAACAAGCAACTCGTACCTCAGCTATGGCGTGGACTCCTACAATGTGAATGTTGCTGGCAATGCCAACTCATCGGATGTCAGCTCTGGATTCTTTTCCATCTCGGAAGTCGTGTCCGCTGCAGATGCCGCCGATGCAGCCGCCAAAGCGGCGGCGGCCAACAAACCGGAGCGTCGAGCCCGTTGCTATGAGTGTGAAATGTGCTCGGCCAATTTTCCGGATCGGGCCCAGCTGCTGGAGCATGTGCATATACACATCTGA
Protein Sequence: MNNQDYGGIQWIQQHASAVDSESDMLESGAADSEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANESGGGTVLITDSGVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNVNSLELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAASIKFEPQQHRQVDDHFYEQEWPLYQEQDQEHDQMQEQQMEQEQLTVANQEMQQASYAAVSDVPAPTAARGRISRLKPKEESTQYIVIAEKQTTDVLQQFVDCEGLAPTLPANATSSDVDANNATENGQAMNASRFPVLDDSKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDSQSLQEHQKTHQFEESNSEYDPASAGDDSASESEPDQLYGDFYCSECGISFHRQDLLRRHAKQMHKLGMGSAVASTVNSVDVDGSADADADADAENTKDAPHCCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHARHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCTADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDGDDYVSDMDLCDLDVENVDDLFDAAETTPPKREKRKRNAAGQTKAASNVVSASALNNNTTLSAKSANGNQDRLWEEKFLQANSNGNANSQLNDDAFKNIFQIDSLVVINDTTLQPVSSSSTSGAPASKTRRSVKNTQQTQQLQTSSRKSTTAAATTGGDDCSKSSASVSSNSRSSSRKKTAKSTKNAASTASTSSSSRPRMIHTEKSRVPPENASRRTRGRSYITRTSTSESNQLGLVKSSGVGSSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQRVPLMYDDTHLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHDRNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVSSSGHTTITTPSSSFSSAARTSRHLRQLTANSGSRATTKRHSGNKTVSTSSSKKSALSSSATSVSKTSNSYLSYGVDSYNVNVAGNANSSDVSSGFFSISEVVSAADAADAAAKAAAANKPERRARCYECEMCSANFPDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579414;
90% Identity: iTF_00585360;
80% Identity: -